-
1
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson S, Bartek J. 2009. The DNA-damage response in human biology and disease. Nature 461(7267):1071-78
-
(2009)
Nature
, vol.461
, Issue.7267
, pp. 1071-1078
-
-
Jackson, S.1
Bartek, J.2
-
2
-
-
77951974344
-
Dealing with DNA damage: Relationships between checkpoint and repair pathways
-
Warmerdam D, Kanaar R. 2010. Dealing with DNA damage: relationships between checkpoint and repair pathways. Mutat. Res. 704(1-3):2-11
-
(2010)
Mutat. Res.
, vol.704
, Issue.1-3
, pp. 2-11
-
-
Warmerdam, D.1
Kanaar, R.2
-
3
-
-
77953229115
-
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
-
Lieber MR. 2010. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu. Rev. Biochem. 79(1):181-211
-
(2010)
Annu. Rev. Biochem.
, vol.79
, Issue.1
, pp. 181-211
-
-
Lieber, M.R.1
-
4
-
-
50649100744
-
Mechanism of eukaryotic homologous recombination
-
San Filippo J, Sung P, Klein H. 2008. Mechanism of eukaryotic homologous recombination. Annu. Rev. Biochem. 77(1):229-57
-
(2008)
Annu. Rev. Biochem.
, vol.77
, Issue.1
, pp. 229-257
-
-
San Filippo, J.1
Sung, P.2
Klein, H.3
-
5
-
-
79952762235
-
Factors determining DNA double-strand break repair pathway choice in G2 phase
-
Shibata A, Conrad S, Birraux J, Geuting V, Barton O, et al. 2011. Factors determining DNA double-strand break repair pathway choice in G2 phase. EMBO J. 30(6):1079-92
-
(2011)
EMBO J.
, vol.30
, Issue.6
, pp. 1079-1092
-
-
Shibata, A.1
Conrad, S.2
Birraux, J.3
Geuting, V.4
Barton, O.5
-
6
-
-
70350763838
-
ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
-
Beucher A, Birraux J, Tchouandong L, Barton O, Shibata A, et al. 2009. ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2. EMBO J. 28(21):3413-27
-
(2009)
EMBO J.
, vol.28
, Issue.21
, pp. 3413-3427
-
-
Beucher, A.1
Birraux, J.2
Tchouandong, L.3
Barton, O.4
Shibata, A.5
-
7
-
-
67650725820
-
The biology of chromatin remodeling complexes
-
Clapier C, Cairns B. 2009. The biology of chromatin remodeling complexes. Annu. Rev. Biochem. 78:273-304
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 273-304
-
-
Clapier, C.1
Cairns, B.2
-
8
-
-
65149084552
-
Crosstalk between histone modifications during the DNA damage response
-
van Attikum H, Gasser S. 2009. Crosstalk between histone modifications during the DNA damage response. Trends Cell Biol. 19(5):207-17
-
(2009)
Trends Cell Biol.
, vol.19
, Issue.5
, pp. 207-217
-
-
Van Attikum, H.1
Gasser, S.2
-
9
-
-
0035313706
-
DNA-PK, ATM and ATR as sensors of DNA damage: Variations on a theme?
-
Durocher D, Jackson SP. 2001. DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme? Curr. Opin. Cell Biol. 13(2):225-31
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, Issue.2
, pp. 225-231
-
-
Durocher, D.1
Jackson, S.P.2
-
10
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
Rogakou E, Boon C, Redon C, Bonner W. 1999. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 146(5):905-16
-
(1999)
J. Cell Biol.
, vol.146
, Issue.5
, pp. 905-916
-
-
Rogakou, E.1
Boon, C.2
Redon, C.3
Bonner, W.4
-
11
-
-
65549129613
-
Formation of dynamic γ-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin
-
Savic V, Yin B, Maas N, Bredemeyer A, Carpenter A, et al. 2009. Formation of dynamic γ-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin. Mol. Cell 34(3):298-310
-
(2009)
Mol. Cell
, vol.34
, Issue.3
, pp. 298-310
-
-
Savic, V.1
Yin, B.2
Maas, N.3
Bredemeyer, A.4
Carpenter, A.5
-
12
-
-
0037062492
-
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX
-
Bassing C, Chua K, Sekiguchi J, Suh H, Whitlow S, et al. 2002. Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX. Proc. Natl. Acad. Sci. USA 99(12):8173-78
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, Issue.12
, pp. 8173-8178
-
-
Bassing, C.1
Chua, K.2
Sekiguchi, J.3
Suh, H.4
Whitlow, S.5
-
13
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
Celeste A, Petersen S, Romanienko P, Fernandez-Capetillo O, Chen H, et al. 2002. Genomic instability in mice lacking histone H2AX. Science 296(5569):922-27
-
(2002)
Science
, vol.296
, Issue.5569
, pp. 922-927
-
-
Celeste, A.1
Petersen, S.2
Romanienko, P.3
Fernandez-Capetillo, O.4
Chen, H.5
-
14
-
-
0036903037
-
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1
-
Fernandez-Capetillo O, Chen H, Celeste A, Ward I, Romanienko P, et al. 2002. DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1. Nat. Cell Biol. 4(12):993-97
-
(2002)
Nat. Cell Biol.
, vol.4
, Issue.12
, pp. 993-997
-
-
Fernandez-Capetillo, O.1
Chen, H.2
Celeste, A.3
Ward, I.4
Romanienko, P.5
-
15
-
-
0037711771
-
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
-
Celeste A, Fernandez-Capetillo O, Kruhlak M, Pilch D, Staudt D, et al. 2003. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat. Cell Biol. 5(7):675-79
-
(2003)
Nat. Cell Biol.
, vol.5
, Issue.7
, pp. 675-679
-
-
Celeste, A.1
Fernandez-Capetillo, O.2
Kruhlak, M.3
Pilch, D.4
Staudt, D.5
-
16
-
-
42249102663
-
γh2AX foci form preferentially in euchromatin after ionising-radiation
-
Cowell I, Sunter N, Singh P, Austin C, Durkacz B, Tilby M. 2007. γH2AX foci form preferentially in euchromatin after ionising-radiation. PLoS ONE 2(10):e1057
-
(2007)
PLoS ONE
, vol.2
, Issue.10
-
-
Cowell, I.1
Sunter, N.2
Singh, P.3
Austin, C.4
Durkacz, B.5
Tilby, M.6
-
17
-
-
34447532525
-
Heterochromatin is refractory to γ-H2AX modification in yeast and mammals
-
Kim J, Kruhlak M, Dotiwala F, Nussenzweig A, Haber J. 2007. Heterochromatin is refractory to γ-H2AX modification in yeast and mammals. J. Cell Biol. 178(2):209-18
-
(2007)
J. Cell Biol.
, vol.178
, Issue.2
, pp. 209-218
-
-
Kim, J.1
Kruhlak, M.2
Dotiwala, F.3
Nussenzweig, A.4
Haber, J.5
-
18
-
-
33644905252
-
Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
-
Kruhlak M, Celeste A, Dellaire G, Fernandez-Capetillo O, Muller W, et al. 2006. Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks. J. Cell Biol. 172(6):823-34
-
(2006)
J. Cell Biol.
, vol.172
, Issue.6
, pp. 823-834
-
-
Kruhlak, M.1
Celeste, A.2
Dellaire, G.3
Fernandez-Capetillo, O.4
Muller, W.5
-
19
-
-
31444445458
-
A phosphatase complex that dephosphorylates γh2AX regulates DNA damage checkpoint recovery
-
Keogh M, Kim J, Downey M, Fillingham J, Chowdhury D, et al. 2006. A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery. Nature 439(7075):497-501
-
(2006)
Nature
, vol.439
, Issue.7075
, pp. 497-501
-
-
Keogh, M.1
Kim, J.2
Downey, M.3
Fillingham, J.4
Chowdhury, D.5
-
20
-
-
46149117962
-
A PP4-phosphatase complex dephosphorylates γ-H2AX generated during DNA replication
-
Chowdhury D, Xu X, Zhong X, Ahmed F, Zhong J, et al. 2008. A PP4-phosphatase complex dephosphorylates γ-H2AX generated during DNA replication. Mol. Cell 31(1):33-46
-
(2008)
Mol. Cell
, vol.31
, Issue.1
, pp. 33-46
-
-
Chowdhury, D.1
Xu, X.2
Zhong, X.3
Ahmed, F.4
Zhong, J.5
-
21
-
-
77749334700
-
Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates γ-H2AX
-
Douglas P, Zhong J, Ye R, Moorhead G, Xu X, Lees-Miller S. 2010. Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates γ-H2AX. Mol. Cell. Biol. 30(6):1368-81
-
(2010)
Mol. Cell. Biol.
, vol.30
, Issue.6
, pp. 1368-1381
-
-
Douglas, P.1
Zhong, J.2
Ye, R.3
Moorhead, G.4
Xu, X.5
Lees-Miller, S.6
-
22
-
-
53249100305
-
PP4 is a γh2AX phosphatase required for recovery from the DNA damage checkpoint
-
Nakada S, Chen G, Gingras A, Durocher D. 2008. PP4 is a γH2AX phosphatase required for recovery from the DNA damage checkpoint. EMBO Rep. 9(10):1019-26
-
(2008)
EMBO Rep.
, vol.9
, Issue.10
, pp. 1019-1026
-
-
Nakada, S.1
Chen, G.2
Gingras, A.3
Durocher, D.4
-
23
-
-
77951064789
-
Wip1 phosphatase is associated with chromatin and dephosphorylates γh2AX to promote checkpoint inhibition
-
Macurek L, Lindqvist A, Voets O, Kool J, Vos H, Medema R. 2010. Wip1 phosphatase is associated with chromatin and dephosphorylates γH2AX to promote checkpoint inhibition. Oncogene 29(15):2281-91
-
(2010)
Oncogene
, vol.29
, Issue.15
, pp. 2281-2291
-
-
Macurek, L.1
Lindqvist, A.2
Voets, O.3
Kool, J.4
Vos, H.5
Medema, R.6
-
24
-
-
77952825226
-
Wip1 directly dephosphorylates γ-H2AX and attenuates the DNA damage response
-
Cha H, Lowe J, Li H, Lee J, Belova G, et al. 2010. Wip1 directly dephosphorylates γ-H2AX and attenuates the DNA damage response. Cancer Res. 70(10):4112-22
-
(2010)
Cancer Res.
, vol.70
, Issue.10
, pp. 4112-4122
-
-
Cha, H.1
Lowe, J.2
Li, H.3
Lee, J.4
Belova, G.5
-
25
-
-
77953323484
-
-
Nguyen T, Slattery S, Moon S, Darlington Y, Lu X, Donehower L. 2010. The oncogenic phosphatase WIP1 negatively regulates nucleotide excision repair. DNA Repair 9(7):813-23
-
(2010)
The Oncogenic Phosphatase WIP1 Negatively Regulates Nucleotide Excision Repair. DNA Repair
, vol.9
, Issue.7
, pp. 813-823
-
-
Nguyen, T.1
Slattery, S.2
Moon, S.3
Darlington, Y.4
Lu, X.5
Donehower, L.6
-
26
-
-
77949267720
-
A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination
-
Lee D, Pan Y, Kanner S, Sung P, Borowiec J, Chowdhury D. 2010. A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination. Nat. Struct. Mol. Biol. 17(3):365-72
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, Issue.3
, pp. 365-372
-
-
Lee, D.1
Pan, Y.2
Kanner, S.3
Sung, P.4
Borowiec, J.5
Chowdhury, D.6
-
27
-
-
47349107760
-
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
-
Goodarzi A, Noon A, Deckbar D, Ziv Y, Shiloh Y, et al. 2008. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol. Cell 31(2):167-77
-
(2008)
Mol. Cell
, vol.31
, Issue.2
, pp. 167-177
-
-
Goodarzi, A.1
Noon, A.2
Deckbar, D.3
Ziv, Y.4
Shiloh, Y.5
-
28
-
-
84861185981
-
Phosphoproteomic analysis reveals that PP4 dephosphorylates KAP-1 impacting the DNA damage response
-
LeeD-H, Goodarzi AA, Adelmant GO, Pan Y, Jeggo PA, et al. 2012. Phosphoproteomic analysis reveals that PP4 dephosphorylates KAP-1 impacting the DNA damage response. EMBO J. 31(10):2403-15
-
(2012)
EMBO J.
, vol.31
, Issue.10
, pp. 2403-2415
-
-
Leed-H Goodarzi, A.A.1
Adelmant, G.O.2
Pan, Y.3
Jeggo, P.A.4
-
29
-
-
70350335541
-
Wip1 confersG2 checkpoint recovery competence by counteracting p53-dependent transcriptional repression
-
Lindqvist A, deBruijn M, Macurek L, Bras A, Mensinga A, et al. 2009. Wip1 confersG2 checkpoint recovery competence by counteracting p53-dependent transcriptional repression. EMBO J. 28(20):3196-206
-
(2009)
EMBO J.
, vol.28
, Issue.20
, pp. 3196-3206
-
-
Lindqvist, A.1
Debruijn, M.2
Macurek, L.3
Bras, A.4
Mensinga, A.5
-
30
-
-
70350223615
-
Phosphorylation and degradation of MdmX is inhibited byWip1 phosphatase in the DNA damage response
-
Zhang X, Lin L, Guo H, Yang J, Jones S, et al. 2009. Phosphorylation and degradation of MdmX is inhibited byWip1 phosphatase in the DNA damage response. Cancer Res. 69(20):7960-68
-
(2009)
Cancer Res.
, vol.69
, Issue.20
, pp. 7960-7968
-
-
Zhang, X.1
Lin, L.2
Guo, H.3
Yang, J.4
Jones, S.5
-
31
-
-
70349441058
-
Ubiquitin-binding domains-from structures to functions
-
Dikic I, Wakatsuki S, Walters K. 2009. Ubiquitin-binding domains-from structures to functions. Nat. Rev. Mol. Cell Biol. 10(10):659-71
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, Issue.10
, pp. 659-671
-
-
Dikic, I.1
Wakatsuki, S.2
Walters, K.3
-
32
-
-
27144529182
-
Ubiquitylation and cell signaling
-
Haglund K, Dikic I. 2005. Ubiquitylation and cell signaling. EMBO J. 24(19):3353-59
-
(2005)
EMBO J.
, vol.24
, Issue.19
, pp. 3353-3359
-
-
Haglund, K.1
Dikic, I.2
-
34
-
-
63049101044
-
Regulatory ubiquitylation in response to DNA double-strand breaks
-
Panier S, Durocher D. 2009. Regulatory ubiquitylation in response to DNA double-strand breaks. DNA Repair 8(4):436-43
-
(2009)
DNA Repair
, vol.8
, Issue.4
, pp. 436-443
-
-
Panier, S.1
Durocher, D.2
-
35
-
-
36749084931
-
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
-
Kolas N, Chapman J, Nakada S, Ylanko J, Chahwan R, et al. 2007. Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science 318(5856):1637-40
-
(2007)
Science
, vol.318
, Issue.5856
, pp. 1637-1640
-
-
Kolas, N.1
Chapman, J.2
Nakada, S.3
Ylanko, J.4
Chahwan, R.5
-
36
-
-
33847413700
-
A critical role for the ubiquitinconjugating enzyme Ubc13 in initiating homologous recombination
-
Zhao G, Sonoda E, Barber L, Oka H, Murakawa Y, et al. 2007. A critical role for the ubiquitinconjugating enzyme Ubc13 in initiating homologous recombination. Mol. Cell 25(5):663-75
-
(2007)
Mol. Cell
, vol.25
, Issue.5
, pp. 663-675
-
-
Zhao, G.1
Sonoda, E.2
Barber, L.3
Oka, H.4
Murakawa, Y.5
-
37
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil C, Mailand N, Bekker-Jensen S, Menard P, Larsen D, et al. 2009. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 136(3):435-46
-
(2009)
Cell
, vol.136
, Issue.3
, pp. 435-446
-
-
Doil, C.1
Mailand, N.2
Bekker-Jensen, S.3
Menard, P.4
Larsen, D.5
-
38
-
-
36249031962
-
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
-
Huen M, Grant R, Manke I, Minn K, Yu X, et al. 2007. RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell 131(5):901-14
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 901-914
-
-
Huen, M.1
Grant, R.2
Manke, I.3
Minn, K.4
Yu, X.5
-
39
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
Mailand N, Bekker-Jensen S, Faustrup H, Melander F, Bartek J, et al. 2007. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 131(5):887-900
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
-
40
-
-
67649404816
-
RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX
-
Pinato S, Scandiuzzi C, Arnaudo N, Citterio E, Gaudino G, Penengo L. 2009. RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX. BMC Mol. Biol. 10:55
-
(2009)
BMC Mol. Biol.
, vol.10
, pp. 55
-
-
Pinato, S.1
Scandiuzzi, C.2
Arnaudo, N.3
Citterio, E.4
Gaudino, G.5
Penengo, L.6
-
41
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
Stewart G, Panier S, Townsend K, Al-Hakim A, Kolas N, et al. 2009. The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell 136(3):420-34
-
(2009)
Cell
, vol.136
, Issue.3
, pp. 420-434
-
-
Stewart, G.1
Panier, S.2
Townsend, K.3
Al-Hakim, A.4
Kolas, N.5
-
42
-
-
84863793933
-
A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase
-
Gatti M, Pinato S, Maspero E, Soffientini P, Polo S, Penengo L. 2012. A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase. Cell Cycle 11(13):2538-44
-
(2012)
Cell Cycle
, vol.11
, Issue.13
, pp. 2538-2544
-
-
Gatti, M.1
Pinato, S.2
Maspero, E.3
Soffientini, P.4
Polo, S.5
Penengo, L.6
-
43
-
-
79951974992
-
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks
-
Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, et al. 2011. Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Mol. Cell 41(5):529-42
-
(2011)
Mol. Cell
, vol.41
, Issue.5
, pp. 529-542
-
-
Moyal, L.1
Lerenthal, Y.2
Gana-Weisz, M.3
Mass, G.4
So, S.5
-
44
-
-
79951971464
-
Regulation of homologous recombination by RNF20-dependent H2B ubiquitination
-
Nakamura K, Kato A, Kobayashi J, Yanagihara H, Sakamoto S, et al. 2011. Regulation of homologous recombination by RNF20-dependent H2B ubiquitination. Mol. Cell 41(5):515-28
-
(2011)
Mol. Cell
, vol.41
, Issue.5
, pp. 515-528
-
-
Nakamura, K.1
Kato, A.2
Kobayashi, J.3
Yanagihara, H.4
Sakamoto, S.5
-
45
-
-
84866388311
-
RNF168 targets a novel ubiquitination site on H2A/H2AX to drive DNA damage signaling
-
Mattirolli F, Vissers JHA, van Dijk WJ, Ikpa P, Cittero E, et al. 2012. RNF168 targets a novel ubiquitination site on H2A/H2AX to drive DNA damage signaling. Cell 150(6):1182-95
-
(2012)
Cell
, vol.150
, Issue.6
, pp. 1182-1195
-
-
Mattirolli, F.1
Vissers, J.H.A.2
Van Dijk, W.J.3
Ikpa, P.4
Cittero, E.5
-
46
-
-
79960034248
-
Chfr and RNF8 synergistically regulate ATM activation
-
Wu J, Chen Y, Lu L-Y, Wu Y, Paulsen MT, et al. 2011. Chfr and RNF8 synergistically regulate ATM activation. Nat. Struct. Mol. Biol. 18(7):761-68
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, Issue.7
, pp. 761-768
-
-
Wu, J.1
Chen, Y.2
Lu, L.-Y.3
Wu, Y.4
Paulsen, M.T.5
-
47
-
-
84862986431
-
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes
-
Bekker-Jensen S, Rendtlew D, Fugger K, Gromova I, Nerstedt A, et al. 2010. HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes. Nat. Cell Biol. 12(1):80-86
-
(2010)
Nat. Cell Biol.
, vol.12
, Issue.1
, pp. 80-86
-
-
Bekker-Jensen, S.1
Rendtlew, D.2
Fugger, K.3
Gromova, I.4
Nerstedt, A.5
-
48
-
-
84861941745
-
DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding zinc finger
-
Rendtlew D, Povlsen L, Villumsen B, Streicher W, Nilsson J, et al. 2012. DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding zinc finger. J. Cell Biol. 197(2):179-87
-
(2012)
J. Cell Biol.
, vol.197
, Issue.2
, pp. 179-187
-
-
Rendtlew, D.1
Povlsen, L.2
Villumsen, B.3
Streicher, W.4
Nilsson, J.5
-
49
-
-
69149088033
-
Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80
-
Sato Y, Yoshikawa A, Mimura H, Yamashita M, Yamagata A, Fukai S. 2009. Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80. EMBO J. 28(16):2461-68
-
(2009)
EMBO J.
, vol.28
, Issue.16
, pp. 2461-2468
-
-
Sato, Y.1
Yoshikawa, A.2
Mimura, H.3
Yamashita, M.4
Yamagata, A.5
Fukai, S.6
-
50
-
-
34249946686
-
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
-
Wang B, Matsuoka S, Ballif B, Zhang D, Smogorzewska A, et al. 2007. Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science 316(5828):1194-98
-
(2007)
Science
, vol.316
, Issue.5828
, pp. 1194-1198
-
-
Wang, B.1
Matsuoka, S.2
Ballif, B.3
Zhang, D.4
Smogorzewska, A.5
-
51
-
-
58549098527
-
E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks
-
Reid L, Shakya R, Modi A, Lokshin M, Cheng J, et al. 2008. E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks. Proc. Natl. Acad. Sci. USA 105(52):20876-81
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, Issue.52
, pp. 20876-20881
-
-
Reid, L.1
Shakya, R.2
Modi, A.3
Lokshin, M.4
Cheng, J.5
-
52
-
-
79953869356
-
The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection
-
Coleman K, Greenberg R. 2011. The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection. J. Biol. Chem. 286(15):13669-80
-
(2011)
J. Biol. Chem.
, vol.286
, Issue.15
, pp. 13669-13680
-
-
Coleman, K.1
Greenberg, R.2
-
53
-
-
79954528832
-
RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci
-
Hu Y, Scully R, Sobhian B, Xie A, Shestakova E, Livingston D. 2011. RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev. 25(7):685-700
-
(2011)
Genes Dev.
, vol.25
, Issue.7
, pp. 685-700
-
-
Hu, Y.1
Scully, R.2
Sobhian, B.3
Xie, A.4
Shestakova, E.5
Livingston, D.6
-
54
-
-
67349168142
-
RAD18 transmits DNA damage signaling to elicit homologous recombination repair
-
Huang J, Huen M, Kim H, Leung C, Glover J, et al. 2009. RAD18 transmits DNA damage signaling to elicit homologous recombination repair. Nat. Cell Biol. 11(5):592-603
-
(2009)
Nat. Cell Biol.
, vol.11
, Issue.5
, pp. 592-603
-
-
Huang, J.1
Huen, M.2
Kim, H.3
Leung, C.4
Glover, J.5
-
55
-
-
84864919890
-
Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks
-
Panier S, Ichijima Y, Fradet-Turcotte A, Leung CCY, Kaustov L, et al. 2012. Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks. Mol. Cell 47:383-95
-
(2012)
Mol. Cell
, vol.47
, pp. 383-395
-
-
Panier, S.1
Ichijima, Y.2
Fradet-Turcotte, A.3
Leung, C.C.Y.4
Kaustov, L.5
-
56
-
-
77957748289
-
BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair
-
Ismail I, Andrin C, McDonald D, Hendzel M. 2010. BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair. J. Cell Biol. 191(1):45-60
-
(2010)
J. Cell Biol.
, vol.191
, Issue.1
, pp. 45-60
-
-
Ismail, I.1
Andrin, C.2
McDonald, D.3
Hendzel, M.4
-
57
-
-
80051494784
-
Monoubiquitination of H2AX regulates DNA damage response signaling
-
Pan M, Peng G, Hung W, Lin S. 2011. Monoubiquitination of H2AX regulates DNA damage response signaling. J. Biol. Chem. 286:28599-607
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 28599-28607
-
-
Pan, M.1
Peng, G.2
Hung, W.3
Lin, S.4
-
58
-
-
77955381770
-
BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery
-
Facchino S, Abdouh M, Chatoo W, Bernier G. 2010. BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery. J. Neurosci. 30(30):10096-111
-
(2010)
J. Neurosci.
, vol.30
, Issue.30
, pp. 10096-10111
-
-
Facchino, S.1
Abdouh, M.2
Chatoo, W.3
Bernier, G.4
-
59
-
-
79956086415
-
BMI1 is recruited to DNA breaks and contributes to DNA damage induced H2A ubiquitination and repair
-
Ginjala V, Nacerddine K, Kulkarni A, Oza J, Hill S, et al. 2011. BMI1 is recruited to DNA breaks and contributes to DNA damage induced H2A ubiquitination and repair. Mol. Cell. Biol. 31:1972-82
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 1972-1982
-
-
Ginjala, V.1
Nacerddine, K.2
Kulkarni, A.3
Oza, J.4
Hill, S.5
-
60
-
-
80052238249
-
The critical role of monoubiquitination of histone H2AX in histone H2AX phosphorylation and DNA damage response
-
Wu C-Y, Kang H-Y, Yang W-L, Wu J, Jeong YS, et al. 2011. The critical role of monoubiquitination of histone H2AX in histone H2AX phosphorylation and DNA damage response. J. Biol. Chem. 286:30806-15
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 30806-30815
-
-
Wu, C.-Y.1
Kang, H.-Y.2
Yang, W.-L.3
Wu, J.4
Jeong, Y.S.5
-
61
-
-
78649349810
-
A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
-
Chou D, Adamson B, Dephoure N, Tan X, Nottke A, et al. 2010. A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage. Proc. Natl. Acad. Sci. USA 107(43):18475-80
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, Issue.43
, pp. 18475-18480
-
-
Chou, D.1
Adamson, B.2
Dephoure, N.3
Tan, X.4
Nottke, A.5
-
62
-
-
84863198650
-
CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage
-
Ismail IH, Gagne JP, Caron MC, McDonald D, Xu Z, et al. 2012. CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage. Nucleic Acids Res. 40(12):5497-510
-
(2012)
Nucleic Acids Res.
, vol.40
, Issue.12
, pp. 5497-5510
-
-
Ismail, I.H.1
Gagne, J.P.2
Caron, M.C.3
McDonald, D.4
Xu, Z.5
-
63
-
-
78650238493
-
The ACF1 complex is required for DNA double-strand break repair in human cells
-
Lan L, Ui A, Nakajima S, Hatakeyama K, Hoshi M, et al. 2010. The ACF1 complex is required for DNA double-strand break repair in human cells. Mol. Cell 40(6):976-87
-
(2010)
Mol. Cell
, vol.40
, Issue.6
, pp. 976-987
-
-
Lan, L.1
Ui, A.2
Nakajima, S.3
Hatakeyama, K.4
Hoshi, M.5
-
64
-
-
77955867565
-
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1
-
Nakada S, Tai I, Panier S, Al-Hakim A, Iemura S, et al. 2010. Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1. Nature 466(7309):941-46
-
(2010)
Nature
, vol.466
, Issue.7309
, pp. 941-946
-
-
Nakada, S.1
Tai, I.2
Panier, S.3
Al-Hakim, A.4
Iemura, S.5
-
65
-
-
84862806447
-
The mechanism of OTUB1-mediated inhibition of ubiquitination
-
Wiener R, Zhang X, Wang T, Wolberger C. 2012. The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature 483(7391):618-22
-
(2012)
Nature
, vol.483
, Issue.7391
, pp. 618-622
-
-
Wiener, R.1
Zhang, X.2
Wang, T.3
Wolberger, C.4
-
66
-
-
84864386119
-
Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin- conjugating enzyme UBC13
-
Sato Y, Yamagata A, Goto-Ito S, Kubota K, Miyamoto R, et al. 2012. Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin- conjugating enzyme UBC13. J. Biol. Chem. 287:25860-68
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 25860-25868
-
-
Sato, Y.1
Yamagata, A.2
Goto-Ito, S.3
Kubota, K.4
Miyamoto, R.5
-
67
-
-
84856801739
-
OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function
-
Juang Y-C, Landry M-C, Sanches M, Vittal V, Leung C, et al. 2012. OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function. Mol. Cell 45(3):384-97
-
(2012)
Mol. Cell
, vol.45
, Issue.3
, pp. 384-397
-
-
Juang, Y.-C.1
Landry, M.-C.2
Sanches, M.3
Vittal, V.4
Leung, C.5
-
68
-
-
84861948252
-
Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks
-
Poulsen M, Lukas C, Lukas J, Bekker-Jensen S, Mailand N. 2012. Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks. J. Cell Biol. 197(2):189-99
-
(2012)
J. Cell Biol.
, vol.197
, Issue.2
, pp. 189-199
-
-
Poulsen, M.1
Lukas, C.2
Lukas, J.3
Bekker-Jensen, S.4
Mailand, N.5
-
69
-
-
84864977706
-
Ring finger protein RNF169 antagonises the ubiquitin-dependent signaling cascade at sites of DNA damage
-
Chen J, Feng W, Jiang J, Deng Y, Huen MSY. 2012. Ring finger protein RNF169 antagonises the ubiquitin-dependent signaling cascade at sites of DNA damage. J. Biol. Chem. 287:27715-22
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 27715-27722
-
-
Chen, J.1
Feng, W.2
Jiang, J.3
Deng, Y.4
Huen, M.S.Y.5
-
70
-
-
84865232294
-
TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes
-
Gudjonsson T, Altmeyer M, Savic V, Toledo L, Dinant C, Grfte M, et al. 2012. TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes. Cell 150:697-709
-
(2012)
Cell
, vol.150
, pp. 697-709
-
-
Gudjonsson, T.1
Altmeyer, M.2
Savic, V.3
Toledo, L.4
Dinant, C.5
Grfte, M.6
-
71
-
-
34547683267
-
SUMO junction-whats your function? New insights through SUMO-interacting motifs
-
Kerscher O. 2007. SUMO junction-whats your function? New insights through SUMO-interacting motifs. EMBO Rep. 8(6):550-55
-
(2007)
EMBO Rep.
, vol.8
, Issue.6
, pp. 550-555
-
-
Kerscher, O.1
-
72
-
-
72449175818
-
Mammalian SUMO E3- ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
-
Galanty Y, Belotserkovskaya R, Coates J, Polo S, Miller K, Jackson S. 2009. Mammalian SUMO E3- ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. Nature 462(7275):935-39
-
(2009)
Nature
, vol.462
, Issue.7275
, pp. 935-939
-
-
Galanty, Y.1
Belotserkovskaya, R.2
Coates, J.3
Polo, S.4
Miller, K.5
Jackson, S.6
-
73
-
-
72449163470
-
The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress
-
Morris J, Boutell C, Keppler M, Densham R, Weekes D, et al. 2009. The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress. Nature 462(7275):886-90
-
(2009)
Nature
, vol.462
, Issue.7275
, pp. 886-890
-
-
Morris, J.1
Boutell, C.2
Keppler, M.3
Densham, R.4
Weekes, D.5
-
74
-
-
84861765707
-
RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair
-
Galanty Y, Belotserkovskaya R, Coates J, Jackson SP. 2012. RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair. Genes Dev. 26(11):1179-95
-
(2012)
Genes Dev.
, vol.26
, Issue.11
, pp. 1179-1195
-
-
Galanty, Y.1
Belotserkovskaya, R.2
Coates, J.3
Jackson, S.P.4
-
75
-
-
84861784690
-
SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage
-
Yin Y, Seifert A, Chua JS, Maure JF, Golebiowski F, Hay RT. 2012. SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage. Genes Dev. 26(11):1196-208
-
(2012)
Genes Dev.
, vol.26
, Issue.11
, pp. 1196-1208
-
-
Yin, Y.1
Seifert, A.2
Chua, J.S.3
Maure, J.F.4
Golebiowski, F.5
Hay, R.T.6
-
76
-
-
84873704658
-
RNF4 is required for DNA double-strand break repair in vivo
-
Vyas R, Kumar R, Clermont F, Helfricht A, Kalev P, et al. 2012. RNF4 is required for DNA double-strand break repair in vivo. Cell Death Differ. 20(3):490-502
-
(2012)
Cell Death Differ.
, vol.20
, Issue.3
, pp. 490-502
-
-
Vyas, R.1
Kumar, R.2
Clermont, F.3
Helfricht, A.4
Kalev, P.5
-
77
-
-
84863846456
-
Sumoylation of MDC1 is important for proper DNA damage response
-
Luo K, Zhang H, Wang L, Yuan J, Lou Z. 2012. Sumoylation of MDC1 is important for proper DNA damage response. EMBO J. 31(13):3008-19
-
(2012)
EMBO J.
, vol.31
, Issue.13
, pp. 3008-3019
-
-
Luo, K.1
Zhang, H.2
Wang, L.3
Yuan, J.4
Lou, Z.5
-
78
-
-
79952256559
-
Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining
-
Fnu S, Williamson E, De Haro L, Brenneman M, Wray J, et al. 2011. Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining. Proc. Natl. Acad. Sci. USA 108(2):540-45
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, Issue.2
, pp. 540-545
-
-
Fnu, S.1
Williamson, E.2
De Haro, L.3
Brenneman, M.4
Wray, J.5
-
79
-
-
82955249089
-
Double-strand breakinduced transcriptional silencing is associated with loss of tri-methylation at H3K4
-
Seiler DM, Rouquette J, Schmid VJ, Strickfaden H, Ottmann C, et al. 2011. Double-strand breakinduced transcriptional silencing is associated with loss of tri-methylation at H3K4. Chromosome Res. 19(7):883-99
-
(2011)
Chromosome Res.
, vol.19
, Issue.7
, pp. 883-899
-
-
Seiler, D.M.1
Rouquette, J.2
Schmid, V.J.3
Strickfaden, H.4
Ottmann, C.5
-
80
-
-
33845666681
-
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
-
Botuyan M, Lee J, Ward I, Kim J, Thompson J, et al. 2006. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 127(7):1361-73
-
(2006)
Cell
, vol.127
, Issue.7
, pp. 1361-1373
-
-
Botuyan, M.1
Lee, J.2
Ward, I.3
Kim, J.4
Thompson, J.5
-
81
-
-
33847247383
-
Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain
-
Grenon M, Costelloe T, Jimeno S, OShaughnessy A, Fitzgerald J, et al. 2007. Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain. Yeast 24(2):105-19
-
(2007)
Yeast
, vol.24
, Issue.2
, pp. 105-119
-
-
Grenon, M.1
Costelloe, T.2
Jimeno, S.3
Oshaughnessy, A.4
Fitzgerald, J.5
-
82
-
-
25444466892
-
Role of Dot1-dependent histoneH3methylation in G1 and S phase DNA damage checkpoint functions of Rad9
-
Wysocki R, Javaheri A, Allard S, Sha F, Čoté J, Kron S. 2005. Role of Dot1-dependent histoneH3methylation in G1 and S phase DNA damage checkpoint functions of Rad9. Mol. Cell. Biol. 25(19):8430-43
-
(2005)
Mol. Cell. Biol.
, vol.25
, Issue.19
, pp. 8430-8443
-
-
Wysocki, R.1
Javaheri, A.2
Allard, S.3
Sha, F.4
Čoté, J.5
Kron, S.6
-
83
-
-
9244252580
-
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
-
Huyen Y, Zgheib O, Ditullio R, Gorgoulis V, Zacharatos P, et al. 2004. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature 432(7015):406-11
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 406-411
-
-
Huyen, Y.1
Zgheib, O.2
Ditullio, R.3
Gorgoulis, V.4
Zacharatos, P.5
-
84
-
-
79952074043
-
Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor
-
Fitzgerald J, Moureau S, Drogaris P, OConnell E, Abshiru N, et al. 2011. Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor. PLoS ONE 6(2):e14714
-
(2011)
PLoS ONE
, vol.6
, Issue.2
-
-
Fitzgerald, J.1
Moureau, S.2
Drogaris, P.3
Oconnell, E.4
Abshiru, N.5
-
85
-
-
79551665780
-
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites
-
Pei H, Zhang L, Luo K, Qin Y, Chesi M, et al. 2011. MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites. Nature 470(7332):124-28
-
(2011)
Nature
, vol.470
, Issue.7332
, pp. 124-128
-
-
Pei, H.1
Zhang, L.2
Luo, K.3
Qin, Y.4
Chesi, M.5
-
86
-
-
78149423004
-
Regulation of the histone H4 monomethylase PR-Set7 by CRL4Cdt2-mediated PCNA-dependent degradation during DNA damage
-
Oda H, Hübner M, Beck D, Vermeulen M, Hurwitz J, et al. 2010. Regulation of the histone H4 monomethylase PR-Set7 by CRL4Cdt2-mediated PCNA-dependent degradation during DNA damage. Mol. Cell 40(3):364-76
-
(2010)
Mol. Cell
, vol.40
, Issue.3
, pp. 364-376
-
-
Oda, H.1
Hübner, M.2
Beck, D.3
Vermeulen, M.4
Hurwitz, J.5
-
87
-
-
70349759491
-
BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response
-
Yan Q, Dutt S, Xu R, Graves K, Juszczynski P, et al. 2009. BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response. Mol. Cell 36(1):110-20
-
(2009)
Mol. Cell
, vol.36
, Issue.1
, pp. 110-120
-
-
Yan, Q.1
Dutt, S.2
Xu, R.3
Graves, K.4
Juszczynski, P.5
-
88
-
-
82955233157
-
The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks
-
Acs K, Luijsterburg MS, Ackermann L, Salomons FA, Hoppe T, Dantuma NP. 2011. The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks. Nat. Struct. Mol. Biol. 18(12):1345-50.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, Issue.12
, pp. 1345-1345
-
-
Acs, K.1
Luijsterburg, M.S.2
Ackermann, L.3
Salomons, F.A.4
Hoppe, T.5
Dantuma, N.P.6
-
89
-
-
80455145246
-
The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks
-
Meerang M, Ritz D, Paliwal S, Garajova Z, Bosshard M, et al. 2011. The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks. Nat. Cell Biol. 13(11):1376-82
-
(2011)
Nat. Cell Biol.
, vol.13
, Issue.11
, pp. 1376-1382
-
-
Meerang, M.1
Ritz, D.2
Paliwal, S.3
Garajova, Z.4
Bosshard, M.5
-
90
-
-
84859895529
-
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
-
Mallette FA, Mattiroli F, Cui G, Young LC, Hendzel MJ, et al. 2012. RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites. EMBO J. 31(8):1865-78
-
(2012)
EMBO J.
, vol.31
, Issue.8
, pp. 1865-1878
-
-
Mallette, F.A.1
Mattiroli, F.2
Cui, G.3
Young, L.C.4
Hendzel, M.J.5
-
91
-
-
35148894396
-
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics
-
Ikura T, Tashiro S, Kakino A, Shima H, Jacob N, et al. 2007. DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics. Mol. Cell. Biol. 27(20):7028-40
-
(2007)
Mol. Cell. Biol.
, vol.27
, Issue.20
, pp. 7028-7040
-
-
Ikura, T.1
Tashiro, S.2
Kakino, A.3
Shima, H.4
Jacob, N.5
-
92
-
-
30344444484
-
Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks
-
Murr R, Loizou J, Yang Y, Cuenin C, Li H, et al. 2006. Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks. Nat. Cell Biol. 8(1):91-99
-
(2006)
Nat. Cell Biol.
, vol.8
, Issue.1
, pp. 91-99
-
-
Murr, R.1
Loizou, J.2
Yang, Y.3
Cuenin, C.4
Li, H.5
-
93
-
-
79955613209
-
Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors
-
Ogiwara H, Ui A, Otsuka A, Satoh H, Yokomi I, et al. 2011. Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors. Oncogene 30(18):2135-46
-
(2011)
Oncogene
, vol.30
, Issue.18
, pp. 2135-2146
-
-
Ogiwara, H.1
Ui, A.2
Otsuka, A.3
Satoh, H.4
Yokomi, I.5
-
94
-
-
77953729074
-
Acetylation of H2AX on lysine 36 plays a key role in the DNA double-strand break repair pathway
-
Jiang X, Xu Y, Price B. 2010. Acetylation of H2AX on lysine 36 plays a key role in the DNA double-strand break repair pathway. FEBS Lett. 584(13):2926-30
-
(2010)
FEBS Lett.
, vol.584
, Issue.13
, pp. 2926-2930
-
-
Jiang, X.1
Xu, Y.2
Price, B.3
-
95
-
-
65549113750
-
CBP/p300-mediated acetylation of histone H3 on lysine 56
-
Das C, Lucia M, Hansen K, Tyler J. 2009. CBP/p300-mediated acetylation of histone H3 on lysine 56. Nature 459(7243):113-17
-
(2009)
Nature
, vol.459
, Issue.7243
, pp. 113-117
-
-
Das, C.1
Lucia, M.2
Hansen, K.3
Tyler, J.4
-
96
-
-
77956553913
-
P300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals
-
Vempati R, Jayani R, Notani D, Sengupta A, Galande S, Haldar D. 2010. p300-mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals. J. Biol. Chem. 285(37):28553-64
-
(2010)
J. Biol. Chem.
, vol.285
, Issue.37
, pp. 28553-28564
-
-
Vempati, R.1
Jayani, R.2
Notani, D.3
Sengupta, A.4
Galande, S.5
Haldar, D.6
-
97
-
-
77956341931
-
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining
-
Miller K, Tjeertes J, Coates J, Legube G, Polo S, et al. 2010. Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining. Nat. Struct. Mol. Biol. 17(9):1144-51
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, Issue.9
, pp. 1144-1151
-
-
Miller, K.1
Tjeertes, J.2
Coates, J.3
Legube, G.4
Polo, S.5
-
98
-
-
67650409769
-
Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells
-
Tjeertes J, Miller K, Jackson S. 2009. Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells. EMBO J. 28(13):1878-89
-
(2009)
EMBO J.
, vol.28
, Issue.13
, pp. 1878-1889
-
-
Tjeertes, J.1
Miller, K.2
Jackson, S.3
-
99
-
-
78649533191
-
MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1
-
Li X, Corsa C, Pan P, Wu L, Ferguson D, et al. 2010. MOF and H4 K16 acetylation play important roles in DNA damage repair by modulating recruitment of DNA damage repair protein Mdc1. Mol. Cell. Biol. 30(22):5335-47
-
(2010)
Mol. Cell. Biol.
, vol.30
, Issue.22
, pp. 5335-5347
-
-
Li, X.1
Corsa, C.2
Pan, P.3
Wu, L.4
Ferguson, D.5
-
100
-
-
22544480772
-
HMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells
-
Taipale M, Rea S, Richter K, Vilar A, Lichter P, et al. 2005. hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells. Mol. Cell. Biol. 25(15):6798-810
-
(2005)
Mol. Cell. Biol.
, vol.25
, Issue.15
, pp. 6798-6810
-
-
Taipale, M.1
Rea, S.2
Richter, K.3
Vilar, A.4
Lichter, P.5
-
101
-
-
77954360144
-
MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair
-
Sharma G, So S, Gupta A, Kumar R, Cayrou C, et al. 2010. MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair. Mol. Cell. Biol. 30(14):3582-95
-
(2010)
Mol. Cell. Biol.
, vol.30
, Issue.14
, pp. 3582-3595
-
-
Sharma, G.1
So, S.2
Gupta, A.3
Kumar, R.4
Cayrou, C.5
-
103
-
-
1642308537
-
Poly(ADP-ribosyl)ated chromatin domains: Access granted
-
Rouleau M, Aubin R, Poirier G. 2004. Poly(ADP-ribosyl)ated chromatin domains: access granted. J. Cell Sci. 117:815-25
-
(2004)
J. Cell Sci.
, vol.117
, pp. 815-825
-
-
Rouleau, M.1
Aubin, R.2
Poirier, G.3
-
104
-
-
67649888368
-
Molecular mechanism of poly(ADPribosyl) ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites
-
Altmeyer M, Messner S, Hassa P, Fey M, Hottiger M. 2009. Molecular mechanism of poly(ADPribosyl) ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites. Nucleic Acids Res. 37(11):3723-38
-
(2009)
Nucleic Acids Res.
, vol.37
, Issue.11
, pp. 3723-3738
-
-
Altmeyer, M.1
Messner, S.2
Hassa, P.3
Fey, M.4
Hottiger, M.5
-
105
-
-
77950915348
-
PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA
-
Loseva O, Jemth A, Bryant H, Schuler H, Lehtio L, et al. 2010. PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA. J. Biol. Chem. 285(11):8054-60
-
(2010)
J. Biol. Chem.
, vol.285
, Issue.11
, pp. 8054-8060
-
-
Loseva, O.1
Jemth, A.2
Bryant, H.3
Schuler, H.4
Lehtio, L.5
-
106
-
-
79959363092
-
-
Mao Z, Hine C, Tian X, Van Meter M, Au M, et al. 2011. SIRT6 promotes DNA repair under stress by activating PARP1. Science 332(6036):1443-46
-
(2011)
SIRT6 Promotes DNA Repair under Stress by Activating PARP1. Science
, vol.332
, Issue.6036
, pp. 1443-1446
-
-
Mao, Z.1
Hine, C.2
Tian, X.3
Van Meter, M.4
Au, M.5
-
107
-
-
38049064044
-
Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins
-
Ahel I, Ahel D, Matsusaka T, Clark A, Pines J, et al. 2008. Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins. Nature 451(7174):81-85
-
(2008)
Nature
, vol.451
, Issue.7174
, pp. 81-85
-
-
Ahel, I.1
Ahel, D.2
Matsusaka, T.3
Clark, A.4
Pines, J.5
-
108
-
-
0038641860
-
A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins
-
Gagne J, Hunter J, Labrecque B, Chabot B, Poirier G. 2003. A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins. Biochem. J. 371(Pt. 2):331-40
-
(2003)
Biochem. J.
, vol.371
, Issue.PART 2
, pp. 331-340
-
-
Gagne, J.1
Hunter, J.2
Labrecque, B.3
Chabot, B.4
Poirier, G.5
-
109
-
-
0027943462
-
Poly(ADP-ribose) catabolism in mammalian cells
-
Lagueux J, Shah G, Menard L, Thomassin H, Duchaine C, et al. 1994. Poly(ADP-ribose) catabolism in mammalian cells. Mol. Cell. Biochem. 138(1-2):45-52
-
(1994)
Mol. Cell. Biochem.
, vol.138
, Issue.1-2
, pp. 45-52
-
-
Lagueux, J.1
Shah, G.2
Menard, L.3
Thomassin, H.4
Duchaine, C.5
-
110
-
-
0034731455
-
Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins
-
Pleschke J, Kleczkowska H, Strohm M, Althaus F. 2000. Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins. J. Biol. Chem. 275(52):40974-80
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.52
, pp. 40974-40980
-
-
Pleschke, J.1
Kleczkowska, H.2
Strohm, M.3
Althaus, F.4
-
111
-
-
69949133036
-
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation
-
Timinszky G, Till S, Hassa P, Hothorn M, Kustatscher G, et al. 2009. A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat. Struct. Mol. Biol. 16(9):923-29
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, Issue.9
, pp. 923-929
-
-
Timinszky, G.1
Till, S.2
Hassa, P.3
Hothorn, M.4
Kustatscher, G.5
-
112
-
-
38049007502
-
Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells
-
Mortusewicz O, Amé J, Schreiber V, Leonhardt H. 2007. Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells. Nucleic Acids Res. 35(22):7665-75
-
(2007)
Nucleic Acids Res.
, vol.35
, Issue.22
, pp. 7665-7675
-
-
Mortusewicz, O.1
Amé, J.2
Schreiber, V.3
Leonhardt, H.4
-
113
-
-
2942703171
-
Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure
-
Poirier G, de Murcia G, Jongstra-Bilen J, Niedergang C, Mandel P. 1982. Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure. Proc. Natl. Acad. Sci. USA 79(11):3423-27
-
(1982)
Proc. Natl. Acad. Sci. USA
, vol.79
, Issue.11
, pp. 3423-3427
-
-
Poirier, G.1
De Murcia, G.2
Jongstra-Bilen, J.3
Niedergang, C.4
Mandel, P.5
-
114
-
-
0142009654
-
A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage
-
Khamisy El S, Masutani M, Suzuki H, Caldecott K. 2003. A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage. Nucleic Acids Res. 31(19):5526-33
-
(2003)
Nucleic Acids Res.
, vol.31
, Issue.19
, pp. 5526-5533
-
-
Khamisy El, S.1
Masutani, M.2
Suzuki, H.3
Caldecott, K.4
-
115
-
-
0031844311
-
XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage
-
Masson M, Niedergang C, Schreiber V, Muller S, Menissier-deMurcia J, de Murcia G. 1998. XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage. Mol. Cell. Biol. 18(6):3563-71
-
(1998)
Mol. Cell. Biol.
, vol.18
, Issue.6
, pp. 3563-3571
-
-
Masson, M.1
Niedergang, C.2
Schreiber, V.3
Muller, S.4
Menissier-Demurcia, J.5
De Murcia, G.6
-
116
-
-
0026507413
-
Role of poly(ADP-ribose) formation inDNArepair
-
Satoh M, Lindahl T. 1992. Role of poly(ADP-ribose) formation inDNArepair. Nature 356(6367):356-58
-
(1992)
Nature
, vol.356
, Issue.6367
, pp. 356-358
-
-
Satoh, M.1
Lindahl, T.2
-
117
-
-
78049376054
-
PARP1 ADP-ribosylates lysine residues of the core histone tails
-
Messner S, Altmeyer M, Zhao H, Pozivil A, Roschitzki B, et al. 2010. PARP1 ADP-ribosylates lysine residues of the core histone tails. Nucleic Acids Res. 38(19):6350-62
-
(2010)
Nucleic Acids Res.
, vol.38
, Issue.19
, pp. 6350-6362
-
-
Messner, S.1
Altmeyer, M.2
Zhao, H.3
Pozivil, A.4
Roschitzki, B.5
-
118
-
-
69949123856
-
Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1
-
Ahel D, Horejsi Z, Wiechens N, Polo S, Garcia-Wilson E, et al. 2009. Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. Science 325(5945):1240-43
-
(2009)
Science
, vol.325
, Issue.5945
, pp. 1240-1243
-
-
Ahel, D.1
Horejsi, Z.2
Wiechens, N.3
Polo, S.4
Garcia-Wilson, E.5
-
119
-
-
69549083315
-
Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler
-
Gottschalk A, Timinszky G, Kong S, Jin J, Cai Y, et al. 2009. Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler. Proc. Natl. Acad. Sci. USA 106(33):13770-74
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, Issue.33
, pp. 13770-13774
-
-
Gottschalk, A.1
Timinszky, G.2
Kong, S.3
Jin, J.4
Cai, Y.5
-
120
-
-
78650745979
-
DNA repair factor APLF is a histone chaperone
-
Mehrotra P, Ahel D, Ryan D, Weston R, Wiechens N, et al. 2011. DNA repair factor APLF is a histone chaperone. Mol. Cell 41(1):46-55
-
(2011)
Mol. Cell
, vol.41
, Issue.1
, pp. 46-55
-
-
Mehrotra, P.1
Ahel, D.2
Ryan, D.3
Weston, R.4
Wiechens, N.5
-
121
-
-
34547116653
-
Human Xip1 (C2orf13) is a novel regulator of cellular responses to DNA strand breaks
-
Bekker-Jensen S, Fugger K, Danielsen J, Gromova I, Sehested M, et al. 2007. Human Xip1 (C2orf13) is a novel regulator of cellular responses to DNA strand breaks. J. Biol. Chem. 282(27):19638-43
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.27
, pp. 19638-19643
-
-
Bekker-Jensen, S.1
Fugger, K.2
Danielsen, J.3
Gromova, I.4
Sehested, M.5
-
122
-
-
34248157719
-
APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks
-
Iles N, Rulten S, Khamisy El S, Caldecott K. 2007. APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks. Mol. Cell. Biol. 27(10):3793-803
-
(2007)
Mol. Cell. Biol.
, vol.27
, Issue.10
, pp. 3793-3803
-
-
Iles, N.1
Rulten, S.2
Khamisy El, S.3
Caldecott, K.4
-
123
-
-
34247245102
-
A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses
-
Kanno S, Kuzuoka H, Sasao S, Hong Z, Lan L, et al. 2007. A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses. EMBO J. 26(8):2094-103
-
(2007)
EMBO J.
, vol.26
, Issue.8
, pp. 2094-2103
-
-
Kanno, S.1
Kuzuoka, H.2
Sasao, S.3
Hong, Z.4
Lan, L.5
-
124
-
-
78650756134
-
PARP-3 and APLF function together to accelerate nonhomologous end-joining
-
Rulten S, Fisher A, Robert I, Zuma M, Rouleau M, et al. 2011. PARP-3 and APLF function together to accelerate nonhomologous end-joining. Mol. Cell 41(1):33-45
-
(2011)
Mol. Cell
, vol.41
, Issue.1
, pp. 33-45
-
-
Rulten, S.1
Fisher, A.2
Robert, I.3
Zuma, M.4
Rouleau, M.5
-
125
-
-
79952599748
-
Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
-
Boehler C, Gauthier L, Mortusewicz O, Biard D, Saliou J, et al. 2011. Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression. Proc. Natl. Acad. Sci. USA 108(7):2783-88
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, Issue.7
, pp. 2783-2788
-
-
Boehler, C.1
Gauthier, L.2
Mortusewicz, O.3
Biard, D.4
Saliou, J.5
-
126
-
-
79960844248
-
Cancer biology and NuRD: A multifaceted chromatin remodeling complex
-
Lai A, Wade P. 2011. Cancer biology and NuRD: a multifaceted chromatin remodeling complex. Nat. Rev. Cancer 11(8):588-96
-
(2011)
Nat. Rev. Cancer
, vol.11
, Issue.8
, pp. 588-596
-
-
Lai, A.1
Wade, P.2
-
127
-
-
70349645266
-
Ageing-related chromatin defects through loss of the NURD complex
-
Pegoraro G, Kubben N, Wickert U, Göhler H, Hoffmann K, Misteli T. 2009. Ageing-related chromatin defects through loss of the NURD complex. Nat. Cell Biol. 11(10):1261-67
-
(2009)
Nat. Cell Biol.
, vol.11
, Issue.10
, pp. 1261-1267
-
-
Pegoraro, G.1
Kubben, N.2
Wickert, U.3
Göhler, H.4
Hoffmann, K.5
Misteli, T.6
-
128
-
-
0033517797
-
Molecular association between ATR and two components of the nucleosome remodeling and deacetylating complex, HDAC2 and CHD4
-
Schmidt D, Schreiber S. 1999. Molecular association between ATR and two components of the nucleosome remodeling and deacetylating complex, HDAC2 and CHD4. Biochemistry 38(44):14711-17
-
(1999)
Biochemistry
, vol.38
, Issue.44
, pp. 14711-14717
-
-
Schmidt, D.1
Schreiber, S.2
-
129
-
-
79960055393
-
KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response
-
Goodarzi A, Kurka T, Jeggo P. 2011. KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response. Nat. Struct. Mol. Biol. 18(7):831-39
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, Issue.7
, pp. 831-839
-
-
Goodarzi, A.1
Kurka, T.2
Jeggo, P.3
-
130
-
-
77956379478
-
The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage
-
Larsen D, Poinsignon C, Gudjonsson T, Dinant C, Payne M, et al. 2010. The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage. J. Cell Biol. 190(5):731-40
-
(2010)
J. Cell Biol.
, vol.190
, Issue.5
, pp. 731-740
-
-
Larsen, D.1
Poinsignon, C.2
Gudjonsson, T.3
Dinant, C.4
Payne, M.5
-
131
-
-
77956387556
-
The NuRD chromatinremodeling complex regulates signaling and repair of DNA damage
-
Smeenk G, Wiegant W, Vrolijk H, Solari A, Pastink A, van Attikum H. 2010. The NuRD chromatinremodeling complex regulates signaling and repair of DNA damage. J. Cell Biol. 190(5):741-49
-
(2010)
J. Cell Biol.
, vol.190
, Issue.5
, pp. 741-749
-
-
Smeenk, G.1
Wiegant, W.2
Vrolijk, H.3
Solari, A.4
Pastink, A.5
Van Attikum, H.6
-
132
-
-
77956870690
-
Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodeling factor CHD4
-
Polo S, Kaidi A, Baskcomb L, Galanty Y, Jackson S. 2010. Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodeling factor CHD4. EMBO J. 29(18):3130-39
-
(2010)
EMBO J.
, vol.29
, Issue.18
, pp. 3130-3139
-
-
Polo, S.1
Kaidi, A.2
Baskcomb, L.3
Galanty, Y.4
Jackson, S.5
-
133
-
-
34249947699
-
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
-
Matsuoka S, Ballif B, Smogorzewska A, McDonald E, Hurov K, et al. 2007. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 316(5828):1160-66
-
(2007)
Science
, vol.316
, Issue.5828
, pp. 1160-1166
-
-
Matsuoka, S.1
Ballif, B.2
Smogorzewska, A.3
McDonald, E.4
Hurov, K.5
-
134
-
-
79960021121
-
ATM mediated phosphorylation of CHD4 contributes to genome maintenance
-
Urquhart A, Gatei M, Richard D, Khanna K. 2011. ATM mediated phosphorylation of CHD4 contributes to genome maintenance. Genome Integr. 2(1):1
-
(2011)
Genome Integr.
, vol.2
, Issue.1
, pp. 1
-
-
Urquhart, A.1
Gatei, M.2
Richard, D.3
Khanna, K.4
-
135
-
-
84861895067
-
A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure
-
Luijsterburg MS, Acs K, Ackermann L, Wiegant WW, Bekker-Jensen S, et al. 2012. A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure. EMBO J. 31(11):2511-27
-
(2012)
EMBO J.
, vol.31
, Issue.11
, pp. 2511-2527
-
-
Luijsterburg, M.S.1
Acs, K.2
Ackermann, L.3
Wiegant, W.W.4
Bekker-Jensen, S.5
-
136
-
-
84863166648
-
Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombination DNA repair, and its deficiency sensitizes cells to poly(ADP-ribose) polymerase (PARP) inhibitor treatment
-
Pan M, Hsieh H, Dai H, Hung W, Li K, et al. 2012. Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombination DNA repair, and its deficiency sensitizes cells to poly(ADP-ribose) polymerase (PARP) inhibitor treatment. J. Biol. Chem. 287(9):6764-72
-
(2012)
J. Biol. Chem.
, vol.287
, Issue.9
, pp. 6764-6772
-
-
Pan, M.1
Hsieh, H.2
Dai, H.3
Hung, W.4
Li, K.5
-
137
-
-
64949113367
-
The SWI/SNF complex and cancer
-
Reisman D, Glaros S, Thompson E. 2009. The SWI/SNF complex and cancer. Oncogene 28(14):1653-68
-
(2009)
Oncogene
, vol.28
, Issue.14
, pp. 1653-1668
-
-
Reisman, D.1
Glaros, S.2
Thompson, E.3
-
138
-
-
0034704078
-
A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1
-
Underhill C, Qutob M, Yee S, Torchia J. 2000. A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1. J. Biol. Chem. 275(51):40463-70
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.51
, pp. 40463-40470
-
-
Underhill, C.1
Qutob, M.2
Yee, S.3
Torchia, J.4
-
139
-
-
77951498720
-
A cooperative activation loop among SWI/SNF, γ-H2AX and H3 acetylation for DNA double-strand break repair
-
Lee H, Park J, Kim S, Kwon S, Kwon J. 2010. A cooperative activation loop among SWI/SNF, γ-H2AX and H3 acetylation for DNA double-strand break repair. EMBO J. 29(8):1434-45
-
(2010)
EMBO J.
, vol.29
, Issue.8
, pp. 1434-1445
-
-
Lee, H.1
Park, J.2
Kim, S.3
Kwon, S.4
Kwon, J.5
-
140
-
-
33748367886
-
Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting γ-H2AX induction
-
Park J, Park E, Lee H, Kim S, Hur S, et al. 2006. Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting γ-H2AX induction. EMBO J. 25(17):3986-97
-
(2006)
EMBO J.
, vol.25
, Issue.17
, pp. 3986-3997
-
-
Park, J.1
Park, E.2
Lee, H.3
Kim, S.4
Hur, S.5
-
141
-
-
67650034511
-
BRIT1/MCPH1 links chromatin remodeling to DNA damage response
-
Peng G, Yim E, Dai H, Jackson A, Burgt I, et al. 2009. BRIT1/MCPH1 links chromatin remodeling to DNA damage response. Nat. Cell Biol. 11(7):865-72
-
(2009)
Nat. Cell Biol.
, vol.11
, Issue.7
, pp. 865-872
-
-
Peng, G.1
Yim, E.2
Dai, H.3
Jackson, A.4
Burgt, I.5
-
142
-
-
33746857684
-
BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer
-
Rai R, Dai H, Multani A, Li K, Chin K, et al. 2006. BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer. Cancer Cell 10(2):145-57
-
(2006)
Cancer Cell
, vol.10
, Issue.2
, pp. 145-157
-
-
Rai, R.1
Dai, H.2
Multani, A.3
Li, K.4
Chin, K.5
-
143
-
-
36849000716
-
MCPH1 functions in an H2AX-dependent but MDC1- independent pathway in response to DNA damage
-
Wood J, Singh N, Mer G, Chen J. 2007. MCPH1 functions in an H2AX-dependent but MDC1- independent pathway in response to DNA damage. J. Biol. Chem. 282(48):35416-23
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.48
, pp. 35416-35423
-
-
Wood, J.1
Singh, N.2
Mer, G.3
Chen, J.4
-
144
-
-
27244445051
-
BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly
-
Lin S, Rai R, Li K, Xu Z, Elledge S. 2005. BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly. Proc. Natl. Acad. Sci. USA 102(42):15105-9
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, Issue.42
, pp. 15105-15109
-
-
Lin, S.1
Rai, R.2
Li, K.3
Xu, Z.4
Elledge, S.5
-
145
-
-
79952468153
-
SnapShot: Chromatin remodeling: ISWI
-
Yadon A, Tsukiyama T. 2011. SnapShot: chromatin remodeling: ISWI. Cell 144(3):453-53
-
(2011)
Cell
, vol.144
, Issue.3
, pp. 453-553
-
-
Yadon, A.1
Tsukiyama, T.2
-
146
-
-
63849187827
-
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions
-
Cook P, Ju B, Telese F, Wang X, Glass C, Rosenfeld M. 2009. Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature 458(7238):591-96
-
(2009)
Nature
, vol.458
, Issue.7238
, pp. 591-596
-
-
Cook, P.1
Ju, B.2
Telese, F.3
Wang, X.4
Glass, C.5
Rosenfeld, M.6
-
147
-
-
80455149670
-
Role for hACF1 in the G2/M damage checkpoint
-
Sánchez-Molina S, Mortusewicz O, Bieber B, Auer S, Eckey M, et al. 2011. Role for hACF1 in the G2/M damage checkpoint. Nucleic Acids Res. 39:8445-56
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 8445-8456
-
-
Sánchez-Molina, S.1
Mortusewicz, O.2
Bieber, B.3
Auer, S.4
Eckey, M.5
-
148
-
-
58149242430
-
WSTF regulates the H2A. X DNA damage response via a novel tyrosine kinase activity
-
Xiao A, Li H, Shechter D, Ahn S, Fabrizio L, et al. 2009. WSTF regulates the H2A. X DNA damage response via a novel tyrosine kinase activity. Nature 457(7225):57-62
-
(2009)
Nature
, vol.457
, Issue.7225
, pp. 57-62
-
-
Xiao, A.1
Li, H.2
Shechter, D.3
Ahn, S.4
Fabrizio, L.5
-
149
-
-
78650536985
-
Human ISWI chromatin-remodeling complexes sample nucleosomes via transient binding reactions and become immobilized at active sites
-
Erdel F, Schubert T, Marth C, Langst G, Rippe K. 2010. Human ISWI chromatin-remodeling complexes sample nucleosomes via transient binding reactions and become immobilized at active sites. Proc. Natl. Acad. Sci. USA 107(46):19873-78
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, Issue.46
, pp. 19873-19878
-
-
Erdel, F.1
Schubert, T.2
Marth, C.3
Langst, G.4
Rippe, K.5
-
150
-
-
84876328368
-
Poly(ADPribosyl) ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling
-
In press
-
Smeenk G, Wiegant WW, Marteijn JA, Luijsterburg MS, Srcoczynski N, et al. 2013. Poly(ADPribosyl) ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling. J. Cell Sci. In press
-
(2013)
J. Cell Sci.
-
-
Smeenk, G.1
Wiegant, W.W.2
Marteijn, J.A.3
Luijsterburg, M.S.4
Srcoczynski, N.5
-
151
-
-
0032493889
-
Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage
-
Lee S, Moore J, Holmes A, Umezu K, Kolodner R, Haber J. 1998. Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell 94(3):399-409
-
(1998)
Cell
, vol.94
, Issue.3
, pp. 399-409
-
-
Lee, S.1
Moore, J.2
Holmes, A.3
Umezu, K.4
Kolodner, R.5
Haber, J.6
-
152
-
-
0036828213
-
Ku affects the CHK1-dependent G2 checkpoint after ionizing radiation
-
Wang X, Li G, Iliakis G, Wang Y. 2002. Ku affects the CHK1-dependent G2 checkpoint after ionizing radiation. Cancer Res. 62(21):6031-34
-
(2002)
Cancer Res.
, vol.62
, Issue.21
, pp. 6031-6034
-
-
Wang, X.1
Li, G.2
Iliakis, G.3
Wang, Y.4
-
153
-
-
67650230540
-
Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A. X is mediated by the protein phosphatase eyes absent
-
Krishnan N, Jeong D, Jung S, Ryu S, Xiao A, et al. 2009. Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A. X is mediated by the protein phosphatase eyes absent. J. Biol. Chem. 284(24):16066-70
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.24
, pp. 16066-16070
-
-
Krishnan, N.1
Jeong, D.2
Jung, S.3
Ryu, S.4
Xiao, A.5
-
154
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
-
Stucki M, Clapperton J, Mohammad D, Yaffe M, Smerdon S, Jackson S. 2005. MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 123(7):1213-26
-
(2005)
Cell
, vol.123
, Issue.7
, pp. 1213-1226
-
-
Stucki, M.1
Clapperton, J.2
Mohammad, D.3
Yaffe, M.4
Smerdon, S.5
Jackson, S.6
-
155
-
-
67349084662
-
Histone H2A. X Tyr142 phosphorylation: A novel sWItCH for apoptosis?
-
Stucki M. 2009. Histone H2A. X Tyr142 phosphorylation: a novel sWItCH for apoptosis? DNA Repair 8(7):873-76
-
(2009)
DNA Repair
, vol.8
, Issue.7
, pp. 873-876
-
-
Stucki, M.1
-
156
-
-
84857033669
-
Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure
-
Shao Z, Li F, Sy SM, Yan W, Zhang Z, et al. 2012. Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure. J. Struct. Biol. 177(2):459-68
-
(2012)
J. Struct. Biol.
, vol.177
, Issue.2
, pp. 459-468
-
-
Shao, Z.1
Li, F.2
Sy, S.M.3
Yan, W.4
Zhang, Z.5
-
157
-
-
84865975058
-
Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A. X by DNA damage response protein MCPH1
-
Singh N, Basnet H, Wiltshire TD, Mohammad DH, Thompson JR, et al. 2012. Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A. X by DNA damage response protein MCPH1. Proc. Natl. Acad. Sci. USA 109(36):14381-86.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, Issue.36
, pp. 14381-14386
-
-
Singh, N.1
Basnet, H.2
Wiltshire, T.D.3
Mohammad, D.H.4
Thompson, J.R.5
-
158
-
-
84866898711
-
The yeast Fun30 and human SMARCAD1 chromatin remodelers promote DNA end resection
-
Costelloe T, Louge R, Tomimatsu N, Mukherjee B, Martini E, et al. 2012. The yeast Fun30 and human SMARCAD1 chromatin remodelers promote DNA end resection. Nature 489:581-84
-
(2012)
Nature
, vol.489
, pp. 581-584
-
-
Costelloe, T.1
Louge, R.2
Tomimatsu, N.3
Mukherjee, B.4
Martini, E.5
-
159
-
-
84866954195
-
The Fun30 ATP-dependent nucleosome remodeler promotes resection of DNA double-strand break ends
-
Chen X, Cui D, Papusha A, Zhang X, Chu C-D, et al. 2012. The Fun30 ATP-dependent nucleosome remodeler promotes resection of DNA double-strand break ends. Nature 489:576-80
-
(2012)
Nature
, vol.489
, pp. 576-580
-
-
Chen, X.1
Cui, D.2
Papusha, A.3
Zhang, X.4
Chu, C.-D.5
-
160
-
-
84868694661
-
The Saccharomyces cerevisiae chromatin remodeler Fun30 regulates DNA end resection and checkpoint deactivation
-
Eapen VV, Sugawara N, Tsabar M, Wu WH, Haber JE. 2012. The Saccharomyces cerevisiae chromatin remodeler Fun30 regulates DNA end resection and checkpoint deactivation. Mol. Cell. Biol. 32(22):4727-40.
-
(2012)
Mol. Cell. Biol.
, vol.32
, Issue.22
, pp. 4727-4727
-
-
Eapen, V.V.1
Sugawara, N.2
Tsabar, M.3
Wu, W.H.4
Haber, J.E.5
-
161
-
-
78649447860
-
The mammalian INO80 complex is recruited to DNA damage sites in an ARP8 dependent manner
-
Kashiwaba S, Kitahashi K, Watanabe T, Onoda F, Ohtsu M, Murakami Y. 2010. The mammalian INO80 complex is recruited to DNA damage sites in an ARP8 dependent manner. Biochem. Biophys. Res. Commun. 402(4):619-25
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.402
, Issue.4
, pp. 619-625
-
-
Kashiwaba, S.1
Kitahashi, K.2
Watanabe, T.3
Onoda, F.4
Ohtsu, M.5
Murakami, Y.6
-
162
-
-
57749191712
-
The human actin-related protein hArp5: Nucleo-cytoplasmic shuttling and involvement in DNA repair
-
Kitayama K, Kamo M, Oma Y, Matsuda R, Uchida T, et al. 2009. The human actin-related protein hArp5: nucleo-cytoplasmic shuttling and involvement in DNA repair. Exp. Cell Res. 315(2):206-17
-
(2009)
Exp. Cell Res.
, vol.315
, Issue.2
, pp. 206-217
-
-
Kitayama, K.1
Kamo, M.2
Oma, Y.3
Matsuda, R.4
Uchida, T.5
-
163
-
-
8644273963
-
The INO80 protein controls homologous recombination in Arabidopsis thaliana
-
Fritsch O, Benvenuto G, Bowler C, Molinier J, Hohn B. 2004. The INO80 protein controls homologous recombination in Arabidopsis thaliana. Mol. Cell 16(3):479-85
-
(2004)
Mol. Cell
, vol.16
, Issue.3
, pp. 479-485
-
-
Fritsch, O.1
Benvenuto, G.2
Bowler, C.3
Molinier, J.4
Hohn, B.5
-
164
-
-
36849066365
-
A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair
-
Wu S, Shi Y, Mulligan P, Gay F, Landry J, et al. 2007. A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair. Nat. Struct. Mol. Biol. 14(12):1165-72
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, Issue.12
, pp. 1165-1172
-
-
Wu, S.1
Shi, Y.2
Mulligan, P.3
Gay, F.4
Landry, J.5
-
165
-
-
83255185774
-
Mammalian Ino80 mediates double-strand break repair through its role in DNA end strand resection
-
Gospodinov A, Vaissiere T, Krastev DB, Legube G, Anachkova B, Herceg Z. 2011. Mammalian Ino80 mediates double-strand break repair through its role in DNA end strand resection. Mol. Cell. Biol. 31(23):4735-45
-
(2011)
Mol. Cell. Biol.
, vol.31
, Issue.23
, pp. 4735-4745
-
-
Gospodinov, A.1
Vaissiere, T.2
Krastev, D.B.3
Legube, G.4
Anachkova, B.5
Herceg, Z.6
-
166
-
-
77957901471
-
Human INO80 chromatin-remodeling complex contributes to DNA double-strand break repair via the expression of Rad54B and XRCC3 genes
-
Park EJ, Hur SK, Kwon J. 2010. Human INO80 chromatin-remodeling complex contributes to DNA double-strand break repair via the expression of Rad54B and XRCC3 genes. Biochem. J. 431(2):179-87
-
(2010)
Biochem. J.
, vol.431
, Issue.2
, pp. 179-187
-
-
Park, E.J.1
Hur, S.K.2
Kwon, J.3
-
167
-
-
1942439646
-
The highly conserved and multifunctional NuA4 HAT complex
-
Doyon Y, Čoté J. 2004. The highly conserved and multifunctional NuA4 HAT complex. Curr. Opin. Genet. Dev. 14(2):147-54
-
(2004)
Curr. Opin. Genet. Dev.
, vol.14
, Issue.2
, pp. 147-154
-
-
Doyon, Y.1
Čoté, J.2
-
168
-
-
77957738825
-
The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair
-
Xu Y, Sun Y, Jiang X, Ayrapetov M, Moskwa P, et al. 2010. The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair. J. Cell Biol. 191(1):31-43
-
(2010)
J. Cell Biol.
, vol.191
, Issue.1
, pp. 31-43
-
-
Xu, Y.1
Sun, Y.2
Jiang, X.3
Ayrapetov, M.4
Moskwa, P.5
-
169
-
-
0034682736
-
Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis
-
Ikura T, Ogryzko V, Grigoriev M, Groisman R, Wang J, et al. 2000. Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell 102(4):463-73
-
(2000)
Cell
, vol.102
, Issue.4
, pp. 463-473
-
-
Ikura, T.1
Ogryzko, V.2
Grigoriev, M.3
Groisman, R.4
Wang, J.5
-
170
-
-
33746601439
-
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway
-
Ziv Y, Bielopolski D, Galanty Y, Lukas C, Taya Y, et al. 2006. Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway. Nat. Cell Biol. 8(8):870-76
-
(2006)
Nat. Cell Biol.
, vol.8
, Issue.8
, pp. 870-876
-
-
Ziv, Y.1
Bielopolski, D.2
Galanty, Y.3
Lukas, C.4
Taya, Y.5
-
171
-
-
75949122330
-
53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair
-
Noon A, Shibata A, Rief N, Lobrich M, Stewart G, et al. 2010. 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair. Nat. Cell Biol. 12(2):177-84
-
(2010)
Nat. Cell Biol.
, vol.12
, Issue.2
, pp. 177-184
-
-
Noon, A.1
Shibata, A.2
Rief, N.3
Lobrich, M.4
Stewart, G.5
-
172
-
-
0033601106
-
Sin meets NuRD and other tails of repression
-
Knoepfler P, Eisenman R. 1999. Sin meets NuRD and other tails of repression. Cell 99(5):447-50
-
(1999)
Cell
, vol.99
, Issue.5
, pp. 447-450
-
-
Knoepfler, P.1
Eisenman, R.2
-
173
-
-
79955507697
-
HP1α recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair
-
Baldeyron C, Soria G, Roche D, Cook A, Almouzni G. 2011. HP1α recruitment to DNA damage by p150CAF-1 promotes homologous recombination repair. J. Cell Biol. 193(1):81-95
-
(2011)
J. Cell Biol.
, vol.193
, Issue.1
, pp. 81-95
-
-
Baldeyron, C.1
Soria, G.2
Roche, D.3
Cook, A.4
Almouzni, G.5
-
174
-
-
44449136965
-
HP1-β mobilization promotes chromatin changes that initiate the DNA damage response
-
Ayoub N, Jeyasekharan A, Bernal J, Venkitaraman A. 2008. HP1-β mobilization promotes chromatin changes that initiate the DNA damage response. Nature 453(7195):682-86
-
(2008)
Nature
, vol.453
, Issue.7195
, pp. 682-686
-
-
Ayoub, N.1
Jeyasekharan, A.2
Bernal, J.3
Venkitaraman, A.4
-
175
-
-
66149094160
-
Heterochromatin protein 1 is recruited to various types of DNA damage
-
Luijsterburg M, Dinant C, Lans H, Stap J, Wiernasz E, et al. 2009. Heterochromatin protein 1 is recruited to various types of DNA damage. J. Cell Biol. 185(4):577-86
-
(2009)
J. Cell Biol.
, vol.185
, Issue.4
, pp. 577-586
-
-
Luijsterburg, M.1
Dinant, C.2
Lans, H.3
Stap, J.4
Wiernasz, E.5
-
176
-
-
71949105212
-
The emerging role of HP1 in the DNA damage response
-
Dinant C, Luijsterburg M. 2009. The emerging role of HP1 in the DNA damage response. Mol. Cell. Biol. 29(24):6335-40
-
(2009)
Mol. Cell. Biol.
, vol.29
, Issue.24
, pp. 6335-6340
-
-
Dinant, C.1
Luijsterburg, M.2
-
177
-
-
78649449767
-
The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax
-
Goodarzi A, Jeggo P, Lobrich M. 2010. The influence of heterochromatin on DNA double strand break repair: getting the strong, silent type to relax. DNA Repair 9(12):1273-82
-
(2010)
DNA Repair
, vol.9
, Issue.12
, pp. 1273-1282
-
-
Goodarzi, A.1
Jeggo, P.2
Lobrich, M.3
-
178
-
-
34250022502
-
The ATM repair pathway inhibits RNA polymerase i transcription in response to chromosome breaks
-
Kruhlak M, Crouch E, Orlov M, Montano C, Gorski S, et al. 2007. The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks. Nature 447(7145):730-34
-
(2007)
Nature
, vol.447
, Issue.7145
, pp. 730-734
-
-
Kruhlak, M.1
Crouch, E.2
Orlov, M.3
Montano, C.4
Gorski, S.5
-
179
-
-
34548692558
-
Inhibition of transcription at radiation-induced nuclear foci of phosphorylated histone H2AX in mammalian cells
-
Solovjeva L, Svetlova M, Chagin V, Tomilin N. 2007. Inhibition of transcription at radiation-induced nuclear foci of phosphorylated histone H2AX in mammalian cells. Chromosome Res. 15(6):787-97
-
(2007)
Chromosome Res.
, vol.15
, Issue.6
, pp. 787-797
-
-
Solovjeva, L.1
Svetlova, M.2
Chagin, V.3
Tomilin, N.4
-
180
-
-
77953720192
-
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks
-
Shanbhag N, Rafalska-Metcalf I, Balane-Bolivar C, Janicki S, Greenberg R. 2010. ATM-dependent chromatin changes silence transcription in cis to DNA
-
(2010)
Cell
, vol.141
, Issue.6
, pp. 970-981
-
-
Shanbhag, N.1
Rafalska-Metcalf, I.2
Balane-Bolivar, C.3
Janicki, S.4
Greenberg, R.5
-
181
-
-
39549087444
-
Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma
-
Ma N-F, Hu L, Fung JM, Xie D, Zheng B-J, et al. 2007. Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma. Hepatology 47(2):503-10
-
(2007)
Hepatology
, vol.47
, Issue.2
, pp. 503-510
-
-
Ma, N.-F.1
Hu, L.2
Fung, J.M.3
Xie, D.4
Zheng, B.-J.5
-
182
-
-
79251496644
-
SMARCA5 methylation and expression in gastric cancer
-
Gigek C, Lisboa L, Leal M, Silva P, Lima E, et al. 2011. SMARCA5 methylation and expression in gastric cancer. Cancer Investig. 29(2):162-66
-
(2011)
Cancer Investig.
, vol.29
, Issue.2
, pp. 162-166
-
-
Gigek, C.1
Lisboa, L.2
Leal, M.3
Silva, P.4
Lima, E.5
-
183
-
-
79952189457
-
A novel t(4;22) (q31;q12) produces an EWSR1-SMARCA5 fusion in extraskeletal Ewing sarcoma/primitive neuroectodermal tumor
-
Sumegi J, Nishio J, Nelson M, Frayer R, Perry D, Bridge J. 2011. A novel t(4;22) (q31;q12) produces an EWSR1-SMARCA5 fusion in extraskeletal Ewing sarcoma/primitive neuroectodermal tumor. Mod. Pathol. 24(3):333-42
-
(2011)
Mod. Pathol.
, vol.24
, Issue.3
, pp. 333-342
-
-
Sumegi, J.1
Nishio, J.2
Nelson, M.3
Frayer, R.4
Perry, D.5
Bridge, J.6
-
184
-
-
50049135067
-
Deletion mapping of chromosome 4q22-35 and identification of four frequently deleted regions in head and neck cancers
-
Cetin E, Cengiz B, Gunduz E, Gunduz M, Nagatsuka H, et al. 2008. Deletion mapping of chromosome 4q22-35 and identification of four frequently deleted regions in head and neck cancers. Neoplasma 55(4):299-304
-
(2008)
Neoplasma
, vol.55
, Issue.4
, pp. 299-304
-
-
Cetin, E.1
Cengiz, B.2
Gunduz, E.3
Gunduz, M.4
Nagatsuka, H.5
-
185
-
-
0033949274
-
Chromatin remodeling gene SMARCA5 is dysregulated in primitive hematopoietic cells of acute leukemia
-
Stopka T, Zakova D, Fuchs O, Kubrova O, Blafkova J, et al. 2000. Chromatin remodeling gene SMARCA5 is dysregulated in primitive hematopoietic cells of acute leukemia. Leukemia 14(7):1247-52
-
(2000)
Leukemia
, vol.14
, Issue.7
, pp. 1247-1252
-
-
Stopka, T.1
Zakova, D.2
Fuchs, O.3
Kubrova, O.4
Blafkova, J.5
-
186
-
-
36749029369
-
RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling
-
Stewart G, Stankovic T, Byrd P, Wechsler T, Miller E, et al. 2007. RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling. Proc. Natl. Acad. Sci. USA 104(43):16910-15
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, Issue.43
, pp. 16910-16915
-
-
Stewart, G.1
Stankovic, T.2
Byrd, P.3
Wechsler, T.4
Miller, E.5
-
187
-
-
84859423484
-
Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome
-
Van Houdt JKJ, Nowakowska BA, Sousa SB, van Schaik BDC, Seuntjens E, et al. 2012. Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome. Nat. Genet. 44(4):445-49
-
(2012)
Nat. Genet.
, vol.44
, Issue.4
, pp. 445-449
-
-
Van Houdt, J.K.J.1
Nowakowska, B.A.2
Sousa, S.B.3
Van Schaik, B.D.C.4
Seuntjens, E.5
-
188
-
-
84864135697
-
The Coffin-Siris syndrome: A proposed diagnostic approach and assessment of 15 overlapping cases
-
Schrier SA, Bodurtha JN, Burton B, Chudley AE, Chiong MAD, et al. 2012. The Coffin-Siris syndrome: a proposed diagnostic approach and assessment of 15 overlapping cases. Am. J. Med. Genet. 158A(8):1865-76
-
(2012)
Am. J. Med. Genet.
, vol.158 A
, Issue.8
, pp. 1865-1876
-
-
Schrier, S.A.1
Bodurtha, J.N.2
Burton, B.3
Chudley, A.E.4
Chiong, M.A.D.5
-
189
-
-
84862830331
-
Mutations in SWI/SNF chromatin remodeling complex gene ARID1B cause Coffin-Siris syndrome
-
Santen GWE, Aten E, Sun Y, Almomani R, Gilissen C, et al. 2012. Mutations in SWI/SNF chromatin remodeling complex gene ARID1B cause Coffin-Siris syndrome. Nat. Genet. 44(4):379-80
-
(2012)
Nat. Genet.
, vol.44
, Issue.4
, pp. 379-380
-
-
Santen, G.W.E.1
Aten, E.2
Sun, Y.3
Almomani, R.4
Gilissen, C.5
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