Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

Nature

Volumn 462, Issue 7275, 2009, Pages 935-939

  Galanty, Yaron ^a   Belotserkovskaya, Rimma ^a   Coates, Julia ^a   Polo, Sophie ^a   Miller, Kyle M ^a   Jackson, Stephen P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; BRCA1 PROTEIN; DNA; PROTEIN; PROTEIN P53 BINDING PROTEIN 1; PROTEIN PIAS1; PROTEIN PIAS2; PROTEIN RNF168; SUMO 1 PROTEIN; SUMO 2 PROTEIN; SUMO 3 PROTEIN; SUMO PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

AMINO ACID; BIOCHEMISTRY; CHEMICAL BINDING; DNA; ENZYME ACTIVITY; IONIZATION; MAMMAL;

ARTICLE; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; HUMAN; HUMAN CELL; IONIZING RADIATION; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RADIOSENSITIVITY; SUMOYLATION; UBIQUITINATION;

ANIMALS; BRCA1 PROTEIN; CELL LINE; CELL LINE, TUMOR; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-BINDING PROTEINS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; PHOSPHORYLATION; PROTEIN INHIBITORS OF ACTIVATED STAT; PROTEIN STRUCTURE, TERTIARY; REPLICATION PROTEIN A; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

MAMMALIA;

EID: 72449175818     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08657     Document Type: Article

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