MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage

Journal of Biological Chemistry

Volumn 282, Issue 48, 2007, Pages 35416-35423

  Wood, Jamie L ^a,c   Singh, Namit ^b   Mer, Georges ^b   Chen, Junjie ^c  

^a Department of Molecular Pharmacology and Experimental Therapeutics ^*

^b MAYO GRADUATE SCHOOL   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOSOMAL RECESSIVE DISORDERS; DNA DAMAGE RESPONSIVE PATHWAYS; MICROCEPHALIN; WILD TYPES;

BRAIN; CELLS; DNA; PEPTIDES; PHOSPHORYLATION;

GENES;

DOUBLE STRANDED DNA; HISTONE H2AX; MEMBRANE PROTEIN; PROTEIN BRCT; PROTEIN MCPH1; PROTEIN MDC1; PROTEIN S 100; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION;

CELL LINE; CELL NUCLEUS; CELL SEPARATION; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; FLOW CYTOMETRY; HELA CELLS; HISTONES; HUMANS; KINETICS; MODELS, BIOLOGICAL; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PHOSPHORYLATION; TRANS-ACTIVATORS;

EID: 36849000716     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M705245200     Document Type: Article

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