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Volumn 15, Issue 6, 2007, Pages 787-797

Inhibition of transcription at radiation-induced nuclear foci of phosphorylated histone H2AX in mammalian cells

Author keywords

Chromatin; DNA repair; Heterochromatin; Histone H2AX; Phosphorylation; Repressive histone H3 methylations; Transcription

Indexed keywords

5 BROMOURIDINE TRIPHOSPHATE; HISTONE GAMMA H2AX; HISTONE H2AX; HISTONE H3; LYSINE; PHOSPHATE; UNCLASSIFIED DRUG;

EID: 34548692558     PISSN: 09673849     EISSN: 15736849     Source Type: Journal    
DOI: 10.1007/s10577-007-1162-x     Document Type: Article
Times cited : (36)

References (24)
  • 1
    • 0347988236 scopus 로고    scopus 로고
    • Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains
    • Aten JA, Stap J, Krawczyk PM et al. (2004) Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains. Science 303: 92-95.
    • (2004) Science , vol.303 , pp. 92-95
    • Aten, J.A.1    Stap, J.2    Krawczyk, P.M.3
  • 2
    • 33646514631 scopus 로고    scopus 로고
    • Nuclear organization and dynamics of transcription sites in rat sensory ganglia neurons detected by incorporation of 5′-fluorouridine into nascent RNA
    • Casafont I, Navascues J, Pena E, Lafarga M, Berciano MT (2006) Nuclear organization and dynamics of transcription sites in rat sensory ganglia neurons detected by incorporation of 5′-fluorouridine into nascent RNA. Neuroscience 140: 453-462.
    • (2006) Neuroscience , vol.140 , pp. 453-462
    • Casafont, I.1    Navascues, J.2    Pena, E.3    Lafarga, M.4    Berciano, M.T.5
  • 3
    • 10644221120 scopus 로고    scopus 로고
    • Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome
    • Chadwick BP, Willard HF (2004) Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome. Proc Natl Acad Sci USA 101: 17450-17455.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 17450-17455
    • Chadwick, B.P.1    Willard, H.F.2
  • 4
    • 2242433534 scopus 로고    scopus 로고
    • A kinetic framework for a mammalian RNA polymerase in vivo
    • Dundr M, Hoffmann-Rohrer U, Hu Q et al. (2002) A kinetic framework for a mammalian RNA polymerase in vivo. Science 298: 1623-1626.
    • (2002) Science , vol.298 , pp. 1623-1626
    • Dundr, M.1    Hoffmann-Rohrer, U.2    Hu, Q.3
  • 5
    • 34248161049 scopus 로고    scopus 로고
    • Contribution of the serine 129 of histone H2A to chromatin structure
    • Fink M, Imholz D, Thoma F (2007) Contribution of the serine 129 of histone H2A to chromatin structure. Mol Cell Biol 27: 3589-3600.
    • (2007) Mol Cell Biol , vol.27 , pp. 3589-3600
    • Fink, M.1    Imholz, D.2    Thoma, F.3
  • 6
    • 0033628701 scopus 로고    scopus 로고
    • Topoisomerase II as a target for anticancer drugs: When enzymes stop being nice
    • Fortune JM, Osheroff N (2000) Topoisomerase II as a target for anticancer drugs: when enzymes stop being nice. Prog Nucleic Acid Res Mol Biol 6: 221-253.
    • (2000) Prog Nucleic Acid Res Mol Biol , vol.6 , pp. 221-253
    • Fortune, J.M.1    Osheroff, N.2
  • 7
    • 30744445418 scopus 로고    scopus 로고
    • H2AX prevents DNA breaks from progressing to chromosome breaks and translocations
    • Franco S, Gostissa M, Zha S et al. (2006) H2AX prevents DNA breaks from progressing to chromosome breaks and translocations. Mol Cell 21: 201-214.
    • (2006) Mol Cell , vol.21 , pp. 201-214
    • Franco, S.1    Gostissa, M.2    Zha, S.3
  • 9
    • 0037049641 scopus 로고    scopus 로고
    • The transcription cycle of RNA polymerase II in living cells
    • Kimura H, Sugaya K, Cook PR (2002) The transcription cycle of RNA polymerase II in living cells. J Cell Biol 159: 777-782.
    • (2002) J Cell Biol , vol.159 , pp. 777-782
    • Kimura, H.1    Sugaya, K.2    Cook, P.R.3
  • 10
    • 33644905252 scopus 로고    scopus 로고
    • Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
    • Kruhlak MJ, Celeste A, Dellaire G et al. (2006) Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks. J Cell Biol 172: 823-834.
    • (2006) J Cell Biol , vol.172 , pp. 823-834
    • Kruhlak, M.J.1    Celeste, A.2    Dellaire, G.3
  • 11
    • 0033590624 scopus 로고    scopus 로고
    • Inhibition of RNA polymerase II as a trigger for the p53 response
    • Ljungman M, Zhang F, Chen F, Rainbow AJ, McKay BC (1999) Inhibition of RNA polymerase II as a trigger for the p53 response. Oncogene 18: 583-592.
    • (1999) Oncogene , vol.18 , pp. 583-592
    • Ljungman, M.1    Zhang, F.2    Chen, F.3    Rainbow, A.J.4    McKay, B.C.5
  • 12
    • 13444273546 scopus 로고    scopus 로고
    • DNA repair: The importance of phosphorylating histone H2AX
    • Lowndes NF, Toh GW (2005) DNA repair: the importance of phosphorylating histone H2AX. Curr Biol 15: R99-R102.
    • (2005) Curr Biol , vol.15
    • Lowndes, N.F.1    Toh, G.W.2
  • 13
    • 15744362987 scopus 로고    scopus 로고
    • Actinomycin D induces histone gamma-H2AX foci and complex formation of gamma-H2AX with Ku70 and nuclear DNA helicase II
    • Mischo HE, Hemmerich P, Grosse F, Zhang S (2005) Actinomycin D induces histone gamma-H2AX foci and complex formation of gamma-H2AX with Ku70 and nuclear DNA helicase II. J Biol Chem 280: 9586-9594.
    • (2005) J Biol Chem , vol.280 , pp. 9586-9594
    • Mischo, H.E.1    Hemmerich, P.2    Grosse, F.3    Zhang, S.4
  • 14
    • 0042820464 scopus 로고    scopus 로고
    • Dephosphorylation of histone gamma-H2AX during repair of DNA double-strand breaks in mammalian cells and its inhibition by calyculin a
    • Nazarov IB, Smirnova AN, Krutilina RI et al. (2003) Dephosphorylation of histone gamma-H2AX during repair of DNA double-strand breaks in mammalian cells and its inhibition by calyculin A. Radiat Res 160: 309-317.
    • (2003) Radiat Res , vol.160 , pp. 309-317
    • Nazarov, I.B.1    Smirnova, A.N.2    Krutilina, R.I.3
  • 15
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM (1998) DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 273: 5858-5868.
    • (1998) J Biol Chem , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 16
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou EP, Boon C, Redon C, Bonner WM (1999) Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 146: 905-916.
    • (1999) J Cell Biol , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 17
    • 16644387794 scopus 로고    scopus 로고
    • Nascent RNA synthesis in the context of chromatin architecture
    • Sadoni N, Zink D (2004) Nascent RNA synthesis in the context of chromatin architecture. Chromosome Res 12: 439-451.
    • (2004) Chromosome Res , vol.12 , pp. 439-451
    • Sadoni, N.1    Zink, D.2
  • 18
    • 0035141289 scopus 로고    scopus 로고
    • Two-color fluorescence labeling of early and mid-to-late replicating chromatin in living cells
    • Schermelleh L, Solovei I, Zink D, Cremer T (2001) Two-color fluorescence labeling of early and mid-to-late replicating chromatin in living cells. Chromosome Res 9: 77-80.
    • (2001) Chromosome Res , vol.9 , pp. 77-80
    • Schermelleh, L.1    Solovei, I.2    Zink, D.3    Cremer, T.4
  • 19
    • 2642542643 scopus 로고    scopus 로고
    • A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
    • Schotta G, Lachner M, Sarma K et al. (2004). A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev 18: 1251-1262.
    • (2004) Genes Dev , vol.18 , pp. 1251-1262
    • Schotta, G.1    Lachner, M.2    Sarma, K.3
  • 20
    • 0037063355 scopus 로고    scopus 로고
    • End-joining of reconstituted histone H2AX-containing chromatin in vitro by soluble nuclear proteins from human cells
    • Siino JS, Nazarov IB, Zalenskaya IA, Yau PM, Bradbury EM, Tomilin NV (2002) End-joining of reconstituted histone H2AX-containing chromatin in vitro by soluble nuclear proteins from human cells. FEBS Lett 527: 105-108.
    • (2002) FEBS Lett , vol.527 , pp. 105-108
    • Siino, J.S.1    Nazarov, I.B.2    Zalenskaya, I.A.3    Yau, P.M.4    Bradbury, E.M.5    Tomilin, N.V.6
  • 21
    • 0034811207 scopus 로고    scopus 로고
    • Visualization of focal nuclear sites of DNA repair synthesis induced by bleomycin in human cells
    • Tomilin NV, Solovjeva LV, Svetlova MP et al. (2001) Visualization of focal nuclear sites of DNA repair synthesis induced by bleomycin in human cells. Radiat Res 156: 347-354.
    • (2001) Radiat Res , vol.156 , pp. 347-354
    • Tomilin, N.V.1    Solovjeva, L.V.2    Svetlova, M.P.3
  • 22
    • 2142765527 scopus 로고    scopus 로고
    • Nuclear architecture and genome functioning in plants and animals: What can we learn from both?
    • van Driel R, Fransz P (2004) Nuclear architecture and genome functioning in plants and animals: what can we learn from both? Exp Cell Res 296: 86-90.
    • (2004) Exp Cell Res , vol.296 , pp. 86-90
    • Van Driel, R.1    Fransz, P.2
  • 23
    • 0033523776 scopus 로고    scopus 로고
    • Spatial relationship between transcription sites and chromosome territories
    • Verschure PJ, van Der Kraan I, Manders EM, van Driel R (1999) Spatial relationship between transcription sites and chromosome territories. J Cell Biol 147: 13-24.
    • (1999) J Cell Biol , vol.147 , pp. 13-24
    • Verschure, P.J.1    Van Der Kraan, I.2    Manders, E.M.3    Van Driel, R.4
  • 24
    • 24944494068 scopus 로고    scopus 로고
    • A nanomachine for making ends meet: MRN is a flexing scaffold for the repair of DNA double-strand breaks
    • Williams RS, Tainer JA (2005) A nanomachine for making ends meet: MRN is a flexing scaffold for the repair of DNA double-strand breaks. Mol Cell 19: 724-726.
    • (2005) Mol Cell , vol.19 , pp. 724-726
    • Williams, R.S.1    Tainer, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.