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Volumn 197, Issue 2, 2012, Pages 189-199

Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; PROTEIN RNF 169; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; BRCA1 PROTEIN, HUMAN; CARRIER PROTEIN; DNA; DNA BINDING PROTEIN; NUCLEAR PROTEIN; RAP80 PROTEIN, HUMAN; RNF168 PROTEIN, HUMAN; RNF169 PROTEIN, HUMAN; RNF8 PROTEIN, HUMAN; SIGNAL PEPTIDE; SMALL INTERFERING RNA; TP53BP1 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE; ZINC FINGER PROTEIN;

EID: 84861948252     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201109100     Document Type: Article
Times cited : (108)

References (36)
  • 1
    • 82955233157 scopus 로고    scopus 로고
    • The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks
    • Acs, K., M.S. Luijsterburg, L. Ackermann, F.A. Salomons, T. Hoppe, and N.P. Dantuma. 2011. The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks. Nat. Struct. Mol. Biol. 18:1345-1350. http://dx.doi.org/10.1038/nsmb.2188
    • (2011) Nat. Struct. Mol. Biol , vol.18 , pp. 1345-1350
    • Acs, K.1    Luijsterburg, M.S.2    Ackermann, L.3    Salomons, F.A.4    Hoppe, T.5    Dantuma, N.P.6
  • 2
    • 78649450619 scopus 로고    scopus 로고
    • Assembly and function of DNA doublestrand break repair foci in mammalian cells
    • Bekker-Jensen, S., and N. Mailand. 2010. Assembly and function of DNA doublestrand break repair foci in mammalian cells. DNA Repair (Amst.). 9:1219- 1228. http://dx.doi.org/10.1016/j.dnarep.2010.09.010
    • (2010) DNA Repair (Amst. ) , vol.9 , pp. 1219-1228
    • Bekker-Jensen, S.1    Mailand, N.2
  • 3
    • 33646117239 scopus 로고    scopus 로고
    • Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
    • Bekker-Jensen, S., C. Lukas, R. Kitagawa, F. Melander, M.B. Kastan, J. Bartek, and J. Lukas. 2006. Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J. Cell Biol. 173:195-206. http://dx.doi.org/10.1083/jcb.200510130
    • (2006) J. Cell Biol , vol.173 , pp. 195-206
    • Bekker-Jensen, S.1    Lukas, C.2    Kitagawa, R.3    Melander, F.4    Kastan, M.B.5    Bartek, J.6    Lukas, J.7
  • 4
    • 77951057068 scopus 로고    scopus 로고
    • 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination
    • Bothmer, A., D.F. Robbiani, N. Feldhahn, A. Gazumyan, A. Nussenzweig, and M.C. Nussenzweig. 2010. 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination. J. Exp. Med. 207:855-865. http://dx.doi.org/10.1084/jem.20100244
    • (2010) J. Exp. Med , vol.207 , pp. 855-865
    • Bothmer, A.1    Robbiani, D.F.2    Feldhahn, N.3    Gazumyan, A.4    Nussenzweig, A.5    Nussenzweig, M.C.6
  • 7
    • 78649336706 scopus 로고    scopus 로고
    • The DNA damage response: making it safe to play with knives
    • Ciccia, A., and S.J. Elledge. 2010. The DNA damage response: making it safe to play with knives. Mol. Cell. 40:179-204. http://dx.doi.org/10.1016/j.molcel.2010.09.019
    • (2010) Mol. Cell , vol.40 , pp. 179-204
    • Ciccia, A.1    Elledge, S.J.2
  • 8
    • 79953869356 scopus 로고    scopus 로고
    • The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection
    • Coleman, K.A., and R.A. Greenberg. 2011. The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection. J. Biol. Chem. 286:13669-13680. http://dx.doi.org/10.1074/jbc.M110.213728
    • (2011) J. Biol. Chem , vol.286 , pp. 13669-13680
    • Coleman, K.A.1    Greenberg, R.A.2
  • 9
    • 59049091728 scopus 로고    scopus 로고
    • RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
    • Doil, C., N. Mailand, S. Bekker-Jensen, P. Menard, D.H. Larsen, R. Pepperkok, J. Ellenberg, S. Panier, D. Durocher, J. Bartek, et al. 2009. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell. 136:435-446. http://dx.doi.org/10.1016/j.cell.2008.12.041
    • (2009) Cell , vol.136 , pp. 435-446
    • Doil, C.1    Mailand, N.2    Bekker-Jensen, S.3    Menard, P.4    Larsen, D.H.5    Pepperkok, R.6    Ellenberg, J.7    Panier, S.8    Durocher, D.9    Bartek, J.10
  • 10
    • 72449175818 scopus 로고    scopus 로고
    • Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
    • Galanty, Y., R. Belotserkovskaya, J. Coates, S. Polo, K.M. Miller, and S.P. Jackson. 2009. Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. Nature. 462:935-939. http://dx.doi.org/10.1038/nature08657
    • (2009) Nature , vol.462 , pp. 935-939
    • Galanty, Y.1    Belotserkovskaya, R.2    Coates, J.3    Polo, S.4    Miller, K.M.5    Jackson, S.P.6
  • 11
    • 79954528832 scopus 로고    scopus 로고
    • RAP80- directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci
    • Hu, Y., R. Scully, B. Sobhian, A. Xie, E. Shestakova, and D.M. Livingston. 2011. RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev. 25:685-700. http://dx.doi.org/10.1101/gad.2011011
    • (2011) Genes Dev , vol.25 , pp. 685-700
    • Hu, Y.1    Scully, R.2    Sobhian, B.3    Xie, A.4    Shestakova, E.5    Livingston, D.M.6
  • 12
    • 36249031962 scopus 로고    scopus 로고
    • RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
    • Huen, M.S., R. Grant, I. Manke, K. Minn, X. Yu, M.B. Yaffe, and J. Chen. 2007. RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell. 131:901-914. http://dx.doi.org/10.1016/j.cell.2007.09.041
    • (2007) Cell , vol.131 , pp. 901-914
    • Huen, M.S.1    Grant, R.2    Manke, I.3    Minn, K.4    Yu, X.5    Yaffe, M.B.6    Chen, J.7
  • 13
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • Jackson, S.P., and J. Bartek. 2009. The DNA-damage response in human biology and disease. Nature. 461:1071-1078. http://dx.doi.org/10.1038/nature08467
    • (2009) Nature , vol.461 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 14
    • 34249950879 scopus 로고    scopus 로고
    • Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response
    • Kim, H., J. Chen, and X. Yu. 2007. Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response. Science. 316:1202-1205. http://dx.doi.org/10.1126/science.1139621
    • (2007) Science , vol.316 , pp. 1202-1205
    • Kim, H.1    Chen, J.2    Yu, X.3
  • 16
    • 38049115657 scopus 로고    scopus 로고
    • The mechanism of human nonhomologous DNA end joining
    • Lieber, M.R. 2008. The mechanism of human nonhomologous DNA end joining. J. Biol. Chem. 283:1-5. http://dx.doi.org/10.1074/jbc.R700039200
    • (2008) J. Biol. Chem , vol.283 , pp. 1-5
    • Lieber, M.R.1
  • 17
  • 18
    • 0037341599 scopus 로고    scopus 로고
    • Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
    • Lukas, C., J. Falck, J. Bartkova, J. Bartek, and J. Lukas. 2003. Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage. Nat. Cell Biol. 5:255-260. http://dx.doi.org/10.1038/ncb945
    • (2003) Nat. Cell Biol , vol.5 , pp. 255-260
    • Lukas, C.1    Falck, J.2    Bartkova, J.3    Bartek, J.4    Lukas, J.5
  • 19
    • 33746429958 scopus 로고    scopus 로고
    • Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress
    • Mailand, N., S. Bekker-Jensen, J. Bartek, and J. Lukas. 2006. Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress. Mol. Cell. 23:307-318. http://dx.doi.org/10.1016/j.molcel.2006.06.016
    • (2006) Mol. Cell , vol.23 , pp. 307-318
    • Mailand, N.1    Bekker-Jensen, S.2    Bartek, J.3    Lukas, J.4
  • 20
    • 36248966246 scopus 로고    scopus 로고
    • RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
    • Mailand, N., S. Bekker-Jensen, H. Faustrup, F. Melander, J. Bartek, C. Lukas, and J. Lukas. 2007. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell. 131:887-900. http://dx.doi.org/10.1016/j.cell.2007.09.040
    • (2007) Cell , vol.131 , pp. 887-900
    • Mailand, N.1    Bekker-Jensen, S.2    Faustrup, H.3    Melander, F.4    Bartek, J.5    Lukas, C.6    Lukas, J.7
  • 21
    • 62849083222 scopus 로고    scopus 로고
    • The emerging role of nuclear architecture in DNA repair and genome maintenance
    • Misteli, T., and E. Soutoglou. 2009. The emerging role of nuclear architecture in DNA repair and genome maintenance. Nat. Rev. Mol. Cell Biol. 10:243- 254. http://dx.doi.org/10.1038/nrm2651
    • (2009) Nat. Rev. Mol. Cell Biol , vol.10 , pp. 243-254
    • Misteli, T.1    Soutoglou, E.2
  • 25
    • 79955613209 scopus 로고    scopus 로고
    • Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors
    • Ogiwara, H., A. Ui, A. Otsuka, H. Satoh, I. Yokomi, S. Nakajima, A. Yasui, J. Yokota, and T. Kohno. 2011. Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors. Oncogene. 30:2135-2146. http://dx.doi.org/10.1038/onc.2010.592
    • (2011) Oncogene , vol.30 , pp. 2135-2146
    • Ogiwara, H.1    Ui, A.2    Otsuka, A.3    Satoh, H.4    Yokomi, I.5    Nakajima, S.6    Yasui, A.7    Yokota, J.8    Kohno, T.9
  • 26
    • 63049101044 scopus 로고    scopus 로고
    • Regulatory ubiquitylation in response to DNA double-strand breaks
    • Panier, S., and D. Durocher. 2009. Regulatory ubiquitylation in response to DNA double-strand breaks. DNA Repair (Amst.). 8:436-443. http://dx.doi.org/10.1016/j.dnarep.2009.01.013
    • (2009) DNA Repair (Amst. ) , vol.8 , pp. 436-443
    • Panier, S.1    Durocher, D.2
  • 27
    • 33646036373 scopus 로고    scopus 로고
    • Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin
    • Penengo, L., M. Mapelli, A.G. Murachelli, S. Confalonieri, L. Magri, A. Musacchio, P.P. Di Fiore, S. Polo, and T.R. Schneider. 2006. Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin. Cell. 124:1183-1195. http://dx.doi.org/10.1016/j.cell.2006.02.020
    • (2006) Cell , vol.124 , pp. 1183-1195
    • Penengo, L.1    Mapelli, M.2    Murachelli, A.G.3    Confalonieri, S.4    Magri, L.5    Musacchio, A.6    Di Fiore, P.P.7    Polo, S.8    Schneider, T.R.9
  • 28
    • 50649100744 scopus 로고    scopus 로고
    • Mechanism of eukaryotic homologous recombination
    • San Filippo, J., P. Sung, and H. Klein. 2008. Mechanism of eukaryotic homologous recombination. Annu. Rev. Biochem. 77:229-257. http://dx.doi.org/10.1146/annurev.biochem.77.061306.125255
    • (2008) Annu. Rev. Biochem. , vol.77 , pp. 229-257
    • San Filippo, J.1    Sung, P.2    Klein, H.3
  • 30
    • 38049155945 scopus 로고    scopus 로고
    • Regulation of DNA double-strand break repair pathway choice
    • Shrivastav, M., L.P. De Haro, and J.A. Nickoloff. 2008. Regulation of DNA double-strand break repair pathway choice. Cell Res. 18:134-147. http://dx.doi.org/10.1038/cr.2007.111
    • (2008) Cell Res , vol.18 , pp. 134-147
    • Shrivastav, M.1    De Haro, L.P.2    Nickoloff, J.A.3
  • 32
    • 33747889217 scopus 로고    scopus 로고
    • Differential usage of non-homologous end-joining and homologous recombination in double strand break repair
    • Sonoda, E., H. Hochegger, A. Saberi, Y. Taniguchi, and S. Takeda. 2006. Differential usage of non-homologous end-joining and homologous recombination in double strand break repair. DNA Repair (Amst.). 5:1021- 1029. http://dx.doi.org/10.1016/j.dnarep.2006.05.022
    • (2006) DNA Repair (Amst. ). , vol.5 , pp. 1021-1029
    • Sonoda, E.1    Hochegger, H.2    Saberi, A.3    Taniguchi, Y.4    Takeda, S.5
  • 34
    • 34249946686 scopus 로고    scopus 로고
    • Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
    • Wang, B., S. Matsuoka, B.A. Ballif, D. Zhang, A. Smogorzewska, S.P. Gygi, and S.J. Elledge. 2007. Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science. 316:1194-1198. http://dx.doi.org/10.1126/science.1139476
    • (2007) Science , vol.316 , pp. 1194-1198
    • Wang, B.1    Matsuoka, S.2    Ballif, B.A.3    Zhang, D.4    Smogorzewska, A.5    Gygi, S.P.6    Elledge, S.J.7
  • 35
    • 59249095962 scopus 로고    scopus 로고
    • Histone ubiquitination associates with BRCA1-dependent DNA damage response
    • Wu, J., M.S. Huen, L.Y. Lu, L. Ye, Y. Dou, M. Ljungman, J. Chen, and X. Yu. 2009. Histone ubiquitination associates with BRCA1-dependent DNA damage response. Mol. Cell. Biol. 29:849-860. http://dx.doi.org/10.1128/MCB.01302-08
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 849-860
    • Wu, J.1    Huen, M.S.2    Lu, L.Y.3    Ye, L.4    Dou, Y.5    Ljungman, M.6    Chen, J.7    Yu, X.8
  • 36
    • 33845604556 scopus 로고    scopus 로고
    • DNA double-strand break repair: all's well that ends well
    • Wyman, C., and R. Kanaar. 2006. DNA double-strand break repair: all's well that ends well. Annu. Rev. Genet. 40:363-383. http://dx.doi.org/10.1146/annurev.genet.40.110405.090451
    • (2006) Annu. Rev. Genet , vol.40 , pp. 363-383
    • Wyman, C.1    Kanaar, R.2


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