SUMO junction - What's your function? New insights through SUMO-interacting motifs

EMBO Reports

Volumn 8, Issue 6, 2007, Pages 550-555

  Kerscher, Oliver ^a  

^a The College of William and Mary   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SUMO PROTEIN; UBIQUITIN;

CELL NUCLEUS INCLUSION BODY; COVALENT BOND; DNA REPAIR; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REVIEW; TRANSCRIPTION INITIATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS;

EID: 34547683267     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/sj.embor.7400980     Document Type: Review

References (44)

1. Baba D, Maita N, Jee JG, Uchimura Y, Saitoh H, Sugasawa K, Hanaoka F, Tochio H, Hiroaki H, Shirakawa M (2005) Crystal structure of thymine DNA glycosylase conjugated to SUMO-1. Nature 435: 979-982
2. Baba D, Maita N, Jee JG, Uchimura Y, Saitoh H, Sugasawa K, Hanaoka F, Tochio H, Hiroaki H, Shirakawa M (2006) Crystal structure of SUMO-3-modified thymine-DNA glycosylase. J Mol Biol 359: 137-147
3. Boddy MN, Shanahan P, McDonald WH, Lopez-Girona A, Noguchi E, Yates IJ, Russell P (2003) Replication checkpoint kinase Cds1 regulates recombinational repair protein Rad60. Mol Cell Biol 23: 5939-5946
4. Borden KL (2002) Pondering the promyelocytic leukemia protein (PML) puzzle: Possible functions for PML nuclear bodies. Mol Gell Biol 22: 5259-5269
5. Branzei D, Sollier J, Liberi G, Zhao X, Maeda D, Seki M, Enomoto T, Ohta K, Foiani M (2006) Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks. Cell 127 509-522
6. Buchberger A (2002) From UBA to UBX: New words in the ubiquitin vocabulary. Trends Cell Biol 12: 216-221
7. Chupreta S, Holmstrom S, Subramanian L, Iniguez-Lluhi JA (2005) A small conserved surface in SUMO is the critical structural determinant of its transcriptional inhibitory properties. Mol Cell Biol 25: 4272-4282
8. Hannich JT, Lewis A, Kroetz MB, Li SJ, Heide H, Emili A, Hochstrasser M (2005) Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J Biol Chem 280: 4102-4110
9. Hardeland U, Steinacher R, Jiricny J, Schar P (2002) Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover. EMBO J 21: 1456-1464
10. Hartmann-Petersen R, Gordon.C (2004) Integral UBL domain proteins: A family of proteasome interacting proteins. Semin Cell Dev Biol 15: 247-259
11. Flecker CM, Rabiller M, Haglund K, Bayer P, Dikic I (2006) Specification of SUMO1- and SUMO2-interacting motifs. J Biol Chem 281: 16117-16127
12. Hicke L, Schubert HL, Hill CP (2005) Ubiquitin-binding domains. Nat Rev Mol Cell Biol 6: 610-621
13. Hoege C, Pfander B, Moldovan GL, Pyrowolakis G, Jentsch S (2002) RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419: 135-141
14. Hoeller D et al (2006) Regulation of ubiquitin-binding proteins by monoubiquitination. Nat Cell Biol 8: 163-169
15. Huang WC, Ko TP, Li SS, Wang AH (2004) Crystal structures of the human SUMO-2 protein at 1.6 Å and 1.2 Å resolution: Implication on the functional differences of SUMO proteins. Eur J Biochem 271: 4114-4122
16. Hurley JH, Lee S, Prag G (2006) Ubiquitin-binding domains. Biochem J 399: 361-372
17. Johnson ES (2004) Protein modification by SUMO. Annu Rev Biochem 73: 355-382
18. Kerscher O, Felberbaum R, Hochstrasser M (2006) Modification of proteins by ubiquitin and ubiquitin-like proteins. Annu Rev Cell Dev Biol 22: 159-180
19. Krejci L, Van Komen S, Li Y, Villemain J, Reddy MS, Klein H, Ellenberger T, Sung P (2003) DNA helicase Srs2 disrupts the Rad51 presynaptic filament. Nature 423: 305-309
20. Li W, Hesabi B, Babbo A, Pacione C, Liu J, Chen DJ, Nickoloff JA, Shen Z (2000) Regulation of double-strand break-induced mammalian homologous recombination by UBL1, a RAD51-interacting protein. Nucleic Acids Res 28: 1145-1153
21. Lin DY et al (2006) Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors. Mol Cell 24: 341-354
22. Macris MA, Sung P (2005) Multifaceted role of the Saccharomyces cerevisiae Srs2 helicase in homologous recombination regulation. Biochem Soc Trans 33: 1447-1450
23. Mahajan R, Delphin C, Guan T, Gerace L, Melchior F (1997) A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2. Cell 88: 97-107
24. Matunis MJ, Coutavas E, Blobel G (1996) A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex. J Cell Biol 135: 1457-1470
25. Matunis MJ, Zhang XD, Ellis NA (2006) SUMO: The glue that binds. Dev Cell 11: 596-597
26. Minty A, Dumont X, Kaghad M, Caput D (2000) Covalent modification of p73α by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif. J Biol Chem 275: 36316-36323
27. Novatchkova M, Bachmair A, Eisenhaber B, Eisenhaber F (2005) Proteins with two SUMO-like domains in chromatin-associated complexes: The RENi (Rad60-Esc2-NIP45) family. BMC Bioinformatics 6: 22
28. Papouli E, Chen S, Davies AA, Huttner D, Krejci L, Sung P, Ulrich HD (2005) Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p. Mol Cell 19: 123-133
29. Pfander B, Moldovan GL, Sacher M, Hoege C, Jentsch S (2005) SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase. Nature 436: 428-433
30. Quimby BB, Yong-Gonzalez V, Anan T, Strunnikov AV, Dasso M (2006) The promyelocytic leukemia protein stimulates SUMO conjugation in yeast. Oncogene 25: 2999-3005
31. Raffa GD, Wohlschlegel J, Yates JR 3rd, Boddy MN (2006) SUMO-binding motifs mediate the Rad60-dependent response to replicative stress and self association. J Biol Chem 281: 27973-27981
32. Reverter D, Lima CD (2005) Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex. Nature 435: 687-692
33. Rosendorff A, Illanes D, David G, Lin J, Kieff E, Johanssen E (2004) EBNA3C coactivation with EBNA2 requires a SUMO homology domain. J Virol 78: 367-377
34. Seeler JS, Dejean A (2003) Nuclear and unclear functions of SUMO. Nat Rev Mol Cell Biol 4: 690-699
35. Shen TH, Lin HK, Scaglioni PP, Yung TM, Pandolfi PP (2006) The mechanisms of PML-nuclear body formation. Mol Cell 24: 331-339
36. Shen Z, Pardington-Purtymun PE, Corneaux JC, Moyzis RK, Chen DJ (1996a) Associations of UBE21 with RAD52, UBL1, p53, and RAD51 proteins in a yeast two-hybrid system. Genomics 37: 183-186
37. Shen Z, Pardington-Purtymun PE, Corneaux JC, Moyzis RK, Chen DJ (1996b) UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteins. Genomics 36: 271-279
38. Song J, Durrin LK, Wilkinson TA, Krontiris TG, Chen Y (2004) Identification of a SUMO-binding motif that recognizes SUMO-modified proteins. Proc Natl Acad Sci USA 101: 14373-14378
39. Song J, Zhang Z, Hu W, Chen Y (2005) Small ubiquitin-like modifier (SUMO) recognition of a SUMO binding motif: A reversal of the bound orientation. J Biol Chem 280: 40122-40129
40. Steinacher R, Schar P (2005) Functionality of human thymine DNA glycosylase requires SUMO-regulated changes in protein conformation. Curr Biol 15: 616-623
41. Takahashi H, Hatakeyama S, Saitoh H, Nakayama KI (2005) Noncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia protein. J Biol Chem 280: 5611-5621
42. Tatham MH, Kim S, Jaffray E, Song J, Chen Y, Hay RT (2005) Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection. Nat Struct Mol Biol 12: 67-74
43. Ulrich HD (2005) Mutual interactions between the SUMO and ubiquitin systems: A plea of no contest. Trends Cell Biol 15: 525-532
44. Veaute X, Jeusset J, Soustelle C, Kowalczykowski SC, Le Cam E, Fabre F (2003) The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments. Nature 423: 309-312