Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  FitzGerald, Jennifer ^a   Moureau, Sylvie ^a   Drogaris, Paul ^b   O'Connell, Enda ^a   Abshiru, Nebiyu ^b   Verreault, Alain ^b,c   Thibault, Pierre ^b,c   Grenon, Muriel ^a   Lowndes, Noel F ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H4; HISTONE METHYLTRANSFERASE; MESSENGER RNA; PROTEIN 53BP1; PROTEIN DOT1L; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; DOT1L PROTEIN, MOUSE; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; LYSINE; METHYLTRANSFERASE; NONHISTONE PROTEIN; TRP53BP1 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DNA METHYLATION; DNA SEQUENCE; GENE CONTROL; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE LOSS; GENETIC RESISTANCE; GENETIC VARIABILITY; HUMAN VERSUS ANIMAL COMPARISON; IONIZING RADIATION; MASS SPECTROMETRY; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; SPECIES CONSERVATION; WILD TYPE; ANIMAL; CELL LINE; CHROMATIN; DOUBLE STRANDED DNA BREAK; GENE EXPRESSION PROFILING; GENE SILENCING; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA-BINDING PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; LYSINE; METHYLTRANSFERASES; MICE; MICROARRAY ANALYSIS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 79952074043     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014714     Document Type: Article

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