-
1
-
-
0029085781
-
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage
-
Paulovich, A. G., and Hartwell, L. H. A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage. Cell, 82: 841-847, 1995.
-
(1995)
Cell
, vol.82
, pp. 841-847
-
-
Paulovich, A.G.1
Hartwell, L.H.2
-
2
-
-
0030895204
-
When checkpoints fail
-
Paulovich, A. G., Toczyski, D. P., and Hartwell, L. H. When checkpoints fail. Cell, 88: 315-321, 1997.
-
(1997)
Cell
, vol.88
, pp. 315-321
-
-
Paulovich, A.G.1
Toczyski, D.P.2
Hartwell, L.H.3
-
3
-
-
0030052035
-
DNA damage enhances melanogenesis
-
Eller, M. S., Ostrom, K., and Gilchrest, B. A. DNA damage enhances melanogenesis. Proc. Natl. Acad. Sci. USA, 93: 1087-1092, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1087-1092
-
-
Eller, M.S.1
Ostrom, K.2
Gilchrest, B.A.3
-
4
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
Zhou, B-B. S., and Elledge, S. J. The DNA damage response: Putting checkpoints in perspective. Nature (Lond.), 408: 433-439, 2000.
-
(2000)
Nature (Lond.)
, vol.408
, pp. 433-439
-
-
Zhou, B.-B.S.1
Elledge, S.J.2
-
5
-
-
0031607707
-
DNA breakage and repair
-
Jeggo, P. A. DNA breakage and repair. Adv. Genet, 38: 186-218, 1998.
-
(1998)
Adv. Genet
, vol.38
, pp. 186-218
-
-
Jeggo, P.A.1
-
6
-
-
0035451068
-
Genomic integrity and the repair of double-strand DNA breaks
-
Pastink, A., Eeken, J. C. J., and Lohman, P. H. M. Genomic integrity and the repair of double-strand DNA breaks. Mutat. Res, 480-481: 37-50, 2001.
-
(2001)
Mutat. Res.
, vol.480
, Issue.481
, pp. 37-50
-
-
Pastink, A.1
Eeken, J.C.J.2
Lohman, P.H.M.3
-
7
-
-
0035796042
-
Homologous recombinational repair of DNA ensures mammalian chromosome stability
-
Thompson, L. H., and Schild, D. Homologous recombinational repair of DNA ensures mammalian chromosome stability. Mutat. Res., 477: 131-153, 2001.
-
(2001)
Mutat. Res.
, vol.477
, pp. 131-153
-
-
Thompson, L.H.1
Schild, D.2
-
8
-
-
0029778191
-
Requirement for Ku80 in growth and immunoglobulin V(D)J recombination
-
Nussenzweig, A., Chen, C., da Costa Scares, V., Sanchez, M., Kokol, K., Nussenzweig, M. C., and Li, G. C. Requirement for Ku80 in growth and immunoglobulin V(D)J recombination. Nature (Lond.), 382: 551-555, 1996.
-
(1996)
Nature (Lond.)
, vol.382
, pp. 551-555
-
-
Nussenzweig, A.1
Chen, C.2
Da Costa Scares, V.3
Sanchez, M.4
Kokol, K.5
Nussenzweig, M.C.6
Li, G.C.7
-
9
-
-
0030576534
-
Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
-
Zhu, C., Bogue, M. A., Lim, D-S., Hasty, P., and Roth, D. B. Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell, 86: 379-389, 1996.
-
(1996)
Cell
, vol.86
, pp. 379-389
-
-
Zhu, C.1
Bogue, M.A.2
Lim, D.-S.3
Hasty, P.4
Roth, D.B.5
-
10
-
-
0031471226
-
Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: The effects of ionizing radiation on growth, survival, and development
-
Nussenzweig, A., Sokol, K., Burgman, P., Li, L., and Li, G. C. Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: The effects of ionizing radiation on growth, survival, and development. Proc. Natl. Acad. Sci. USA, 94: 13588-13593, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13588-13593
-
-
Nussenzweig, A.1
Sokol, K.2
Burgman, P.3
Li, L.4
Li, G.C.5
-
11
-
-
0032113987
-
Ku70: A candidate tumor suppressor gene for murine T cell lymphoma
-
Li, G. C., Ouyang, H., Li, X., Nagasawa, H., Little, J. B., Chen, D. J., Ling, C. C., Fuks, Z., and Cordon-Cardo, C. Ku70: a candidate tumor suppressor gene for murine T cell lymphoma. Mol. Cell, 2: 1-8, 1998.
-
(1998)
Mol. Cell
, vol.2
, pp. 1-8
-
-
Li, G.C.1
Ouyang, H.2
Li, X.3
Nagasawa, H.4
Little, J.B.5
Chen, D.J.6
Ling, C.C.7
Fuks, Z.8
Cordon-Cardo, C.9
-
12
-
-
0035977007
-
Genetic analysis of the DNA-dependent protein kinase reveals an inhibitory role of Ku in late S-G2 phase DNA double-strand break repair
-
Fukushima, T., Takata, M., Morrison, C., Araki, R., Fujimori, A., Abe, M., Tatsumi, K., Jasin, M., Dhar, P. K., Sonoda, E., Chiba, T., and Takeda, S. Genetic analysis of the DNA-dependent protein kinase reveals an inhibitory role of Ku in late S-G2 phase DNA double-strand break repair. J Biol. Chem., 276: 44413-44418, 2001.
-
(2001)
J Biol. Chem.
, vol.276
, pp. 44413-44418
-
-
Fukushima, T.1
Takata, M.2
Morrison, C.3
Araki, R.4
Fujimori, A.5
Abe, M.6
Tatsumi, K.7
Jasin, M.8
Dhar, P.K.9
Sonoda, E.10
Chiba, T.11
Takeda, S.12
-
13
-
-
0035893363
-
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells
-
Pierce, A. J., Hu, P., Han, M., Ellis, N., and Jasin, M. Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev., 15: 3237-3242, 2001.
-
(2001)
Genes Dev.
, vol.15
, pp. 3237-3242
-
-
Pierce, A.J.1
Hu, P.2
Han, M.3
Ellis, N.4
Jasin, M.5
-
14
-
-
0032530658
-
Homologous recombination and non-homologous end-joining pathways of DNA double-strand break
-
Takata, M., Sasaki, M. S., Sonoda, E., Morrison, C., Hashimoto, M., Utsumi, H., Yamaguchi-Iwai, Y., Shinohara, A., and Takeda, S. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break. EMBO J. 17: 5497-5508, 1998.
-
(1998)
EMBO J.
, vol.17
, pp. 5497-5508
-
-
Takata, M.1
Sasaki, M.S.2
Sonoda, E.3
Morrison, C.4
Hashimoto, M.5
Utsumi, H.6
Yamaguchi-Iwai, Y.7
Shinohara, A.8
Takeda, S.9
-
15
-
-
0037068770
-
Ku affects the ATM-dependent S-phase checkpoint following ionizing radiation
-
Zhou, X-Y., Wang, X., Wang, H., Chen, D. J., Li, G. C., Iliakis, G., and Wang, Y. Ku affects the ATM-dependent S-phase checkpoint following ionizing radiation. Oncogene, 21: 6377-6381, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 6377-6381
-
-
Zhou, X.-Y.1
Wang, X.2
Wang, H.3
Chen, D.J.4
Li, G.C.5
Iliakis, G.6
Wang, Y.7
-
16
-
-
0032998125
-
Rejoining of DNA double strand breaks in Ku80-deficient mouse fibroblasts
-
Wachsberger, P. R., Li, W-H., Guo, M., Chen, D., Cheong, N., Ling, C. C., and Iliakis, G. Rejoining of DNA double strand breaks in Ku80-deficient mouse fibroblasts. Radial. Res, 151: 398-407, 1999.
-
(1999)
Radial. Res.
, vol.151
, pp. 398-407
-
-
Wachsberger, P.R.1
Li, W.-H.2
Guo, M.3
Chen, D.4
Cheong, N.5
Ling, C.C.6
Iliakis, G.7
-
17
-
-
0035947651
-
The radioresistance to killing of Al-5 cells derives from activation of the Chkl pathway
-
Hu, B., Zhou, X. Y., Wang, X., Zeng, Z. C., Iliakis, G., and Wang, Y. The radioresistance to killing of Al-5 cells derives from activation of the Chkl pathway. J. Biol. Chem, 276: 17693-17698, 2001.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 17693-17698
-
-
Hu, B.1
Zhou, X.Y.2
Wang, X.3
Zeng, Z.C.4
Iliakis, G.5
Wang, Y.6
-
18
-
-
0036569855
-
Ku affects the Ataxia and Rad 3-related/Chkl-dependent S-phase checkpoint response after camptothecin treatment
-
Wang, H., Wang, X., Zhou, X. Y., Chen, D. J., Li, G. C, Iliakis, G., and Wang, Y. Ku affects the Ataxia and Rad 3-related/Chkl-dependent S-phase checkpoint response after camptothecin treatment. Cancer Res., 62: 2483-2487. 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 2483-2487
-
-
Wang, H.1
Wang, X.2
Zhou, X.Y.3
Chen, D.J.4
Li, G.C.5
Iliakis, G.6
Wang, Y.7
-
19
-
-
0037085932
-
An ATM-independent S phase Checkpoint Response Involves CHKl Pathway
-
Zhou, X-Y., Wang, X., Hu, B., Guan, J., Iliakis, G., and Wang, Y. An ATM-independent S phase Checkpoint Response Involves CHKl Pathway. Cancer Res, 62: 1598-1603, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 1598-1603
-
-
Zhou, X.-Y.1
Wang, X.2
Hu, B.3
Guan, J.4
Iliakis, G.5
Wang, Y.6
-
20
-
-
0029829249
-
Defect in multiple cell cycle checkpoints in ataxia-telangiectasia postirradiation
-
Beamish, H., Williams, R., Chen, P., and Lavin, M. F. Defect in multiple cell cycle checkpoints in ataxia-telangiectasia postirradiation. J. Biol. Chem, 271: 20486-20493, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20486-20493
-
-
Beamish, H.1
Williams, R.2
Chen, P.3
Lavin, M.F.4
-
21
-
-
0030969423
-
Fragments of ATM which have dominant-negative or complementing activity
-
Morgan, S. E., Lovly, C., Pandita, T. K., Shiloh, Y., and Kastan, M. B. Fragments of ATM which have dominant-negative or complementing activity. Mol. Cell. Biol, 17: 2020-2029, 1997.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2020-2029
-
-
Morgan, S.E.1
Lovly, C.2
Pandita, T.K.3
Shiloh, Y.4
Kastan, M.B.5
-
22
-
-
0035032649
-
Involvement of Brcal in S-Phase and G2-phase checkpoints after ionizing irradiation
-
Xu, B., Kim, S-T., and Kastan, M. B. Involvement of Brcal in S-Phase and G2-phase checkpoints after ionizing irradiation. Mol. Cell. Biol, 21: 3445-3450, 2001.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3445-3450
-
-
Xu, B.1
Kim, S.-T.2
Kastan, M.B.3
-
23
-
-
0032189483
-
Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin
-
Sarkaria, J. N., Tibbetts, R. S., Busby, E. C., Kennedy, A. P., Hill, D. E., and Abraham, R. T. Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin. Cancer Res, 58: 4375-4382, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 4375-4382
-
-
Sarkaria, J.N.1
Tibbetts, R.S.2
Busby, E.C.3
Kennedy, A.P.4
Hill, D.E.5
Abraham, R.T.6
-
24
-
-
0033199892
-
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine
-
Sarkaria, J. N., Busby, E. C., Tibbetts, R. S., Roos, P., Taya, Y., Karnitz, L. M., and Abraham, R. T. Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res, 59: 4375-4382, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 4375-4382
-
-
Sarkaria, J.N.1
Busby, E.C.2
Tibbetts, R.S.3
Roos, P.4
Taya, Y.5
Karnitz, L.M.6
Abraham, R.T.7
-
25
-
-
0034053130
-
The Chkl protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01
-
Graves, P. R., Yu, L., Schwarz, J. K., Gales, J., Sausville, E. A., O’Connor, P. M., and Piwnica-Worms, H. The Chkl protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01. J Biol. Chem, 275: 5600-5605, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5600-5605
-
-
Graves, P.R.1
Yu, L.2
Schwarz, J.K.3
Gales, J.4
Sausville, E.A.5
O’Connor, P.M.6
Piwnica-Worms, H.7
-
26
-
-
0034655281
-
The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChkl
-
Busby, E. C., Leistritz, D. F., Abraham, R. T., Karnitz, L. M., and Sarkaria, J. N. The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChkl. Cancer Res, 60: 2108-2112, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 2108-2112
-
-
Busby, E.C.1
Leistritz, D.F.2
Abraham, R.T.3
Karnitz, L.M.4
Sarkaria, J.N.5
-
27
-
-
17644432403
-
2/M DNA damage checkpoint
-
2/M DNA damage checkpoint. Genes Dev, 14: 1448-1459, 2000.
-
(2000)
Genes Dev.
, vol.14
, pp. 1448-1459
-
-
Liu, Q.1
Guntuku, S.2
Cui, X.S.3
Matsuoka, S.4
Cortez, D.5
Tamai, K.6
Luo, G.7
Carattini-Rivera, S.8
DeMayo, F.9
Bradley, A.10
Donehower, L.A.11
Elledge, S.J.12
-
28
-
-
0036510163
-
BRCAl regulates the G2/M checkpoint by activating Chkl kinase upon DNA damage
-
Yarden, R. L., Pardo-Reoyo, S., Sgagias, M., Cowan, K. H., and Brody, L. C. BRCAl regulates the G2/M checkpoint by activating Chkl kinase upon DNA damage. Nat. Gen, 30: 285-289, 2002.
-
(2002)
Nat. Gen.
, vol.30
, pp. 285-289
-
-
Yarden, R.L.1
Pardo-Reoyo, S.2
Sgagias, M.3
Cowan, K.H.4
Brody, L.C.5
-
29
-
-
0034616329
-
2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity
-
2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity. J. Biol. Chem, 275: 10342-10348, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10342-10348
-
-
Zhou, B.-B.S.1
Chaturvedi, P.2
Spring, K.3
Scott, S.P.4
Johanson, R.A.5
Mishra, R.6
Mattern, M.R.7
Winkler, J.D.8
Khanna, K.K.9
-
30
-
-
0034306332
-
Threonine 68 is required for radiation-induced phosphorylation and activation of Cdsl
-
Melchionna, R., Chen, X. B., Blasina, A., and McGowan, C. H. Threonine 68 is required for radiation-induced phosphorylation and activation of Cdsl. Nat. Cell Biol, 2: 762-765, 2000.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 762-765
-
-
Melchionna, R.1
Chen, X.B.2
Blasina, A.3
McGowan, C.H.4
-
31
-
-
0035810054
-
Regulation of G2/M transition by p53
-
Taylor, W. R., and Stark, G. R. Regulation of G2/M transition by p53. Oncogene, 20: 1803-1815, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 1803-1815
-
-
Taylor, W.R.1
Stark, G.R.2
-
32
-
-
0035823105
-
Antisense inhibition of Chk2/ hCdsl expression attenuates DNA damage-induced S and G2 checkpoints and enhances apoptotic activity in HEK-293 cells
-
Yu, Q., Rose, J. H. L., Zhang, H., and Pommier, Y. Antisense inhibition of Chk2/ hCdsl expression attenuates DNA damage-induced S and G2 checkpoints and enhances apoptotic activity in HEK-293 cells. FEBS Lett, 505: 7-12. 2001.
-
(2001)
FEBS Lett.
, vol.505
, pp. 7-12
-
-
Yu, Q.1
Rose, J.H.L.2
Zhang, H.3
Pommier, Y.4
-
33
-
-
0033629383
-
Cell cycle regulation by the Cdc25 phosphatase family
-
Nilsson, I., and Hoffman, l. Cell cycle regulation by the Cdc25 phosphatase family. Prog. Cell Cycle Res, 4: 107-114, 2000.
-
(2000)
Prog. Cell Cycle Res.
, vol.4
, pp. 107-114
-
-
Nilsson, I.1
Hoffman, I.2
-
34
-
-
0035449355
-
Cell cycle checkpoint signaling through the ATM and ATR kinases
-
Abraham, R. T. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev, 15: 2177-2196, 2001.
-
(2001)
Genes Dev.
, vol.15
, pp. 2177-2196
-
-
Abraham, R.T.1
-
35
-
-
0036157566
-
Caffeine induces TP53-independent G(l)-phase arrest and apoptosis in human lung tumor cells in a dose-dependent manner
-
Qi, W., Qiao, D., and Martinez, J. D. Caffeine induces TP53-independent G(l)-phase arrest and apoptosis in human lung tumor cells in a dose-dependent manner. Radiat. Res, 157: 166-174, 2002.
-
(2002)
Radiat. Res.
, vol.157
, pp. 166-174
-
-
Qi, W.1
Qiao, D.2
Martinez, J.D.3
-
36
-
-
0034141562
-
The controlling role of ATM in homologous recombinational repair of DNA damage
-
Morrison, C., Sonoda, E., Takao., N., Shinohara, A., Yamato, K-i., and Takeda, S. The controlling role of ATM in homologous recombinational repair of DNA damage. EMBO J, 19: 463-471, 2000.
-
(2000)
EMBO J.
, vol.19
, pp. 463-471
-
-
Morrison, C.1
Sonoda, E.2
Takao, N.3
Shinohara, A.4
Yamato, K.-I.5
Takeda, S.6
-
37
-
-
0035577796
-
RPA2 phosphorylation after DNA damage by the coordinated action of ATM and DNA-PK
-
Wang, H., Guan, J., Wang, H. C., Perrault, A., Wang, Y., and Iliakis, G. RPA2 phosphorylation after DNA damage by the coordinated action of ATM and DNA-PK. Cancer Res., 61: 8554-8563, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 8554-8563
-
-
Wang, H.1
Guan, J.2
Wang, H.C.3
Perrault, A.4
Wang, Y.5
Iliakis, G.6
|