-
1
-
-
0034818446
-
Post-translational modifications and activation of p53 by genotoxic stresses
-
Appella E, Anderson CW (2001) Post-translational modifications and activation of p53 by genotoxic stresses. Eur J Biochem 268: 2764-2772
-
(2001)
Eur J Biochem
, vol.268
, pp. 2764-2772
-
-
Appella, E.1
Anderson, C.W.2
-
2
-
-
0032508504
-
Enhanced phosphorylation of p53 by ATM in response to DNA damage
-
Banin S, Moyal L, Shieh S, Taya Y, Anderson CW, Chessa L, Smorodinsky NI, Prives C, Reiss Y, Shiloh Y, Ziv Y (1998) Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 281: 1674-1677
-
(1998)
Science
, vol.281
, pp. 1674-1677
-
-
Banin, S.1
Moyal, L.2
Shieh, S.3
Taya, Y.4
Anderson, C.W.5
Chessa, L.6
Smorodinsky, N.I.7
Prives, C.8
Reiss, Y.9
Shiloh, Y.10
Ziv, Y.11
-
3
-
-
47549098471
-
The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint
-
Bassermann F, Frescas D, Guardavaccaro D, Busino L, Peschiaroli A, Pagano M (2008) The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint. Cell 134: 256-267
-
(2008)
Cell
, vol.134
, pp. 256-267
-
-
Bassermann, F.1
Frescas, D.2
Guardavaccaro, D.3
Busino, L.4
Peschiaroli, A.5
Pagano, M.6
-
4
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Andersen CL, Dyrskjot L, Orntoft T, Lukas J et al (2006) Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444: 633-637
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Andersen, C.L.1
Dyrskjot, L.2
Orntoft, T.3
-
5
-
-
42949171936
-
Recurrent initiation: A mechanism for triggering p53 pulses in response to DNA damage
-
Batchelor E, Mock CS, Bhan I, Loewer A, Lahav G (2008) Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage. Mol Cell 30: 277-289
-
(2008)
Mol Cell
, vol.30
, pp. 277-289
-
-
Batchelor, E.1
Mock, C.S.2
Bhan, I.3
Loewer, A.4
Lahav, G.5
-
6
-
-
0036613212
-
Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity
-
Bulavin DV, Demidov ON, Saito S, Kauraniemi P, Phillips C, Amundson SA, Ambrosino C, Sauter G, Nebreda AR, Anderson CW, Kallioniemi A, Fornace AJ, Appella E (2002) Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity. Nat Genet 31 : 210-215
-
(2002)
Nat Genet
, vol.31
, pp. 210-215
-
-
Bulavin, D.V.1
Demidov, O.N.2
Saito, S.3
Kauraniemi, P.4
Phillips, C.5
Amundson, S.A.6
Ambrosino, C.7
Sauter, G.8
Nebreda, A.R.9
Anderson, C.W.10
Kallioniemi, A.11
Fornace, A.J.12
Appella, E.13
-
7
-
-
1842483852
-
Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway
-
Bulavin DV, Phillips C, Nannenga B, Timofeev O, Donehower LA, Anderson CW, Appella E, Fornace AJ (2004) Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway. Nat Genet 36: 343-350
-
(2004)
Nat Genet
, vol.36
, pp. 343-350
-
-
Bulavin, D.V.1
Phillips, C.2
Nannenga, B.3
Timofeev, O.4
Donehower, L.A.5
Anderson, C.W.6
Appella, E.7
Fornace, A.J.8
-
8
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, Brown JP, Sedivy JM, Kinzler KW, Vogelstein B (1998) Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 282: 1497-1501
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
9
-
-
0032508608
-
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
-
Canman CE, Lim DS, Cimprich KA, Taya Y, Tamai K, Sakaguchi K, Appella E, Kastan MB, Siliciano JD (1998) Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281: 1677-1679
-
(1998)
Science
, vol.281
, pp. 1677-1679
-
-
Canman, C.E.1
Lim, D.S.2
Cimprich, K.A.3
Taya, Y.4
Tamai, K.5
Sakaguchi, K.6
Appella, E.7
Kastan, M.B.8
Siliciano, J.D.9
-
10
-
-
46149117962
-
A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication
-
Chowdhury D, Xu X, Zhong X, Ahmed F, Zhong J, Liao J, Dykxhoorn DM, Weinstock DM, Pfeifer GP, Lieberman J (2008) A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication. Mol Cell 31 : 33-46
-
(2008)
Mol Cell
, vol.31
, pp. 33-46
-
-
Chowdhury, D.1
Xu, X.2
Zhong, X.3
Ahmed, F.4
Zhong, J.5
Liao, J.6
Dykxhoorn, D.M.7
Weinstock, D.M.8
Pfeifer, G.P.9
Lieberman, J.10
-
11
-
-
34247099845
-
The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-driven mammary gland tumorigenesis
-
Demidov ON, Kek C, Shreeram S, Timofeev O, Fornace AJ, Appella E, Bulavin DV (2007a) The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-driven mammary gland tumorigenesis. Oncogene 26: 2502-2506
-
(2007)
Oncogene
, vol.26
, pp. 2502-2506
-
-
Demidov, O.N.1
Kek, C.2
Shreeram, S.3
Timofeev, O.4
Fornace, A.J.5
Appella, E.6
Bulavin, D.V.7
-
12
-
-
34547702285
-
Wip1 phosphatase regulates p53-dependent apoptosis of stem cells and tumorigenesis in the mouse intestine
-
Demidov ON, Timofeev O, Lwin HN, Kek C, Appella E, Bulavin DV (2007b) Wip1 phosphatase regulates p53-dependent apoptosis of stem cells and tumorigenesis in the mouse intestine. Cell Stem Cell 1: 180-190
-
(2007)
Cell Stem Cell
, vol.1
, pp. 180-190
-
-
Demidov, O.N.1
Timofeev, O.2
Lwin, H.N.3
Kek, C.4
Appella, E.5
Bulavin, D.V.6
-
13
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco R, Fumagalli M, Cicalese A, Piccinin S, Gasparini P, Luise C, Schurra C, Garre M, Nuciforo PG, Bensimon A, Maestro R, Pelicci PG, di Fagagna FD (2006) Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 444: 638-642
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
Piccinin, S.4
Gasparini, P.5
Luise, C.6
Schurra, C.7
Garre, M.8
Nuciforo, P.G.9
Bensimon, A.10
Maestro, R.11
Pelicci, P.G.12
Di Fagagna, F.D.13
-
14
-
-
36248983372
-
Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation
-
Evans PM, Zhang W, Chen X, Yang J, Bhakat KK, Liu C (2007) Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation. J Biol Chem 282: 33994-34002
-
(2007)
J Biol Chem
, vol.282
, pp. 33994-34002
-
-
Evans, P.M.1
Zhang, W.2
Chen, X.3
Yang, J.4
Bhakat, K.K.5
Liu, C.6
-
15
-
-
0030925222
-
Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner
-
Fiscella M, Zhang HL, Fan SJ, Sakaguchi K, Shen SF, Mercer WE, VandeWoude GF, Oconnor PM, Appella E (1997) Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner. Proc Natl Acad Sci USA 94: 6048-6053
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6048-6053
-
-
Fiscella, M.1
Zhang, H.L.2
Fan, S.J.3
Sakaguchi, K.4
Shen, S.F.5
Mercer, W.E.6
Vandewoude, G.F.7
Oconnor, P.M.8
Appella, E.9
-
16
-
-
0035913162
-
Cdc25B activity is regulated by 14-3-3
-
Forrest A, Gabrielli B (2001) Cdc25B activity is regulated by 14-3-3. Oncogene 20: 4393-4401
-
(2001)
Oncogene
, vol.20
, pp. 4393-4401
-
-
Forrest, A.1
Gabrielli, B.2
-
17
-
-
33745206498
-
Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase
-
Fujimoto H, Onishi N, Kato N, Takekawa M, Xu X, Kosugi A, Kondo T, Imamura M, Oishi I, Yoda A, Minami Y (2006) Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase. Cell Death Differ 13: 1170-1180
-
(2006)
Cell Death Differ
, vol.13
, pp. 1170-1180
-
-
Fujimoto, H.1
Onishi, N.2
Kato, N.3
Takekawa, M.4
Xu, X.5
Kosugi, A.6
Kondo, T.7
Imamura, M.8
Oishi, I.9
Yoda, A.10
Minami, Y.11
-
18
-
-
17044429330
-
A roller coaster ride with the mitotic cyclins
-
Fung TK, Poon RY (2005) A roller coaster ride with the mitotic cyclins. Semin Cell Dev Biol 16: 335-342
-
(2005)
Semin Cell Dev Biol
, vol.16
, pp. 335-342
-
-
Fung, T.K.1
Poon, R.Y.2
-
19
-
-
33645960654
-
Stabilizers and destabilizers controlling cell cycle oscillators
-
Guardavaccaro D, Pagano M (2006) Stabilizers and destabilizers controlling cell cycle oscillators. Mol Cell 22: 1-4
-
(2006)
Mol Cell
, vol.22
, pp. 1-4
-
-
Guardavaccaro, D.1
Pagano, M.2
-
20
-
-
34547946751
-
Chk1 instability is coupled to mitotic cell death of p53-deficient cells in response to virus-induced DNA damage signaling
-
Jurvansuu J, Fragkos M, Ingemarsdotter C, Beard P (2007) Chk1 instability is coupled to mitotic cell death of p53-deficient cells in response to virus-induced DNA damage signaling. J Mol Biol 372: 397-406
-
(2007)
J Mol Biol
, vol.372
, pp. 397-406
-
-
Jurvansuu, J.1
Fragkos, M.2
Ingemarsdotter, C.3
Beard, P.4
-
21
-
-
0033592868
-
Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage
-
Khosravi R, Maya R, Gottlieb T, Oren M, Shiloh Y, Shkedy D (1999) Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage. Proc Natl Acad Sci USA 96: 14973-14977
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14973-14977
-
-
Khosravi, R.1
Maya, R.2
Gottlieb, T.3
Oren, M.4
Shiloh, Y.5
Shkedy, D.6
-
22
-
-
0026006392
-
Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: Evidence for a double block to p34cdc2 kinase activation in vertebrates
-
Krek W, Nigg EA (1991) Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates. EMBO J 11 : 3331-3341
-
(1991)
EMBO J
, vol.11
, pp. 3331-3341
-
-
Krek, W.1
Nigg, E.A.2
-
23
-
-
0842332406
-
Dynamics of the p53-Mdm2 feedback loop in individual cells
-
Lahav G, Rosenfeld N, Sigal A, Geva-Zatorsky N, Levine AJ, Elowitz MB, Alon U (2004) Dynamics of the p53-Mdm2 feedback loop in individual cells. Nat Genet 36: 147-150
-
(2004)
Nat Genet
, vol.36
, pp. 147-150
-
-
Lahav, G.1
Rosenfeld, N.2
Sigal, A.3
Geva-Zatorsky, N.4
Levine, A.J.5
Elowitz, M.B.6
Alon, U.7
-
24
-
-
13944274222
-
FoxM1 is required for execution of the mitotic programme and chromosome stability
-
Laoukili J, Kooistra MRH, Bras A, Kauw J, Kerkhoven RM, Morrison A, Clevers H, Medema RH (2005) FoxM1 is required for execution of the mitotic programme and chromosome stability. Nat Cell Biol 7: 126-U134
-
(2005)
Nat Cell Biol
, vol.7
-
-
Laoukili, J.1
Kooistra, M.R.H.2
Bras, A.3
Kauw, J.4
Kerkhoven, R.M.5
Morrison, A.6
Clevers, H.7
Medema, R.H.8
-
25
-
-
0034633702
-
Generation of oscillations by the p53-Mdm2 feedback loop: A theoretical and experimental study
-
Lev Bar-Or R, Maya R, Segel LA, Alon U, Levine AJ, Oren M (2000) Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study. Proc Natl Acad Sci USA 97: 11250-11255
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11250-11255
-
-
Lev Bar-Or, R.1
Maya, R.2
Segel, L.A.3
Alon, U.4
Levine, A.J.5
Oren, M.6
-
26
-
-
8744229083
-
Characterisation of Cdc25B localisation and nuclear export during the cell cycle and in response to stress
-
Lindqvist A, Kallstrom H, Rosenthal CK (2004) Characterisation of Cdc25B localisation and nuclear export during the cell cycle and in response to stress. J Cell Sci 117: 4979-4990
-
(2004)
J Cell Sci
, vol.117
, pp. 4979-4990
-
-
Lindqvist, A.1
Kallstrom, H.2
Rosenthal, C.K.3
-
27
-
-
65349102972
-
The decision to enter mitosis: Feedback and redundancy in the mitotic entry network
-
Lindqvist A, Roudriguez-Bravo V, Medema RH (2009) The decision to enter mitosis: feedback and redundancy in the mitotic entry network. J Cell Biol 185: 193-202
-
(2009)
J Cell Biol
, vol.185
, pp. 193-202
-
-
Lindqvist, A.1
Roudriguez-Bravo, V.2
Medema, R.H.3
-
28
-
-
34249065507
-
Cyclin B1-Cdk1 activation continues after centrosome separation to control mitotic progression
-
Lindqvist A, van Zon W, Rosenthal CK, Wolthuis RMF (2007) Cyclin B1-Cdk1 activation continues after centrosome separation to control mitotic progression. PLoS Biol 5: 1127-1137
-
(2007)
PLoS Biol
, vol.5
, pp. 1127-1137
-
-
Lindqvist, A.1
Van Zon, W.2
Rosenthal, C.K.3
Wolthuis, R.M.F.4
-
29
-
-
35148893194
-
The Wip1 phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop
-
Lu X, Ma O, Nguyen TA, Jones SN, Oren M, Donehower LA (2007) The Wip1 phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop. Cancer Cell 12: 342-354
-
(2007)
Cancer Cell
, vol.12
, pp. 342-354
-
-
Lu, X.1
Ma, O.2
Nguyen, T.A.3
Jones, S.N.4
Oren, M.5
Donehower, L.A.6
-
30
-
-
4344560876
-
The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair
-
Lu XB, Bocangel D, Nannenga B, Yamaguchi H, Appella E, Donehower LA (2004) The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair. Mol Cell 15: 621-634
-
(2004)
Mol Cell
, vol.15
, pp. 621-634
-
-
Lu, X.B.1
Bocangel, D.2
Nannenga, B.3
Yamaguchi, H.4
Appella, E.5
Donehower, L.A.6
-
31
-
-
18844405191
-
PPM1D dephosphor-ylates Chk1 and p53 and abrogates cell cycle checkpoints
-
Lu XB, Nannenga B, Donehower LA (2005) PPM1D dephosphor-ylates Chk1 and p53 and abrogates cell cycle checkpoints. Genes Dev 19: 1162-1174
-
(2005)
Genes Dev
, vol.19
, pp. 1162-1174
-
-
Lu, X.B.1
Nannenga, B.2
Donehower, L.A.3
-
32
-
-
51349144633
-
Pololike kinase-1 is activated by aurora A to promote checkpoint recovery
-
Macurek L, Lindqvist A, Lim D, Lampson MA, Klompmaker R, Freire R, Clouin C, Taylor SS, Yaffe MB, Medema RH (2008) Pololike kinase-1 is activated by aurora A to promote checkpoint recovery. Nature 455: 119-123
-
(2008)
Nature
, vol.455
, pp. 119-123
-
-
MacUrek, L.1
Lindqvist, A.2
Lim, D.3
Lampson, M.A.4
Klompmaker, R.5
Freire, R.6
Clouin, C.7
Taylor, S.S.8
Yaffe, M.B.9
Medema, R.H.10
-
33
-
-
0842324788
-
Recycling the cell cycle: Cyclins revisited
-
Murray AW (2004) Recycling the cell cycle: cyclins revisited. Cell 116: 221-234
-
(2004)
Cell
, vol.116
, pp. 221-234
-
-
Murray, A.W.1
-
34
-
-
53249100305
-
PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint
-
Nakada S, Chen GI, Gingras AC, Durocher D (2008) PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint. EMBO Rep 9: 1019-1026
-
(2008)
EMBO Rep
, vol.9
, pp. 1019-1026
-
-
Nakada, S.1
Chen, G.I.2
Gingras, A.C.3
Durocher, D.4
-
35
-
-
33747005627
-
Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice
-
Nannenga B, Lu XB, Dumble M, Van Maanen M, Nguyen TA, Sutton R, Kumar TR, Donehower LA (2006) Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice. Mol Carcinog 45: 594-604
-
(2006)
Mol Carcinog
, vol.45
, pp. 594-604
-
-
Nannenga, B.1
Lu, X.B.2
Dumble, M.3
Van Maanen, M.4
Nguyen, T.A.5
Sutton, R.6
Kumar, T.R.7
Donehower, L.A.8
-
36
-
-
33847382384
-
The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase
-
Oliva-Trastoy M, Berthonaud V, Chevalier A, Ducrot C, Marsolier-Kergoat MC, Mann C, Leteurtre F (2007) The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase. Oncogene 26: 1449-1458
-
(2007)
Oncogene
, vol.26
, pp. 1449-1458
-
-
Oliva-Trastoy, M.1
Berthonaud, V.2
Chevalier, A.3
Ducrot, C.4
Marsolier-Kergoat, M.C.5
Mann, C.6
Leteurtre, F.7
-
37
-
-
40049086948
-
PPM1D silencing by RNA interference inhibits proliferation and induces apoptosis in breast cancer cell lines with wild-type p53
-
Parssinen J, Alarmo EL, Karhu R, Kallioniemi A (2008) PPM1D silencing by RNA interference inhibits proliferation and induces apoptosis in breast cancer cell lines with wild-type p53. Cancer Genet Cytogenet 182: 33-39
-
(2008)
Cancer Genet Cytogenet
, vol.182
, pp. 33-39
-
-
Parssinen, J.1
Alarmo, E.L.2
Karhu, R.3
Kallioniemi, A.4
-
38
-
-
39149136831
-
A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D
-
Rayter S, Elliott R, Travers J, Rowlands MG, Richardson TB, Boxall K, Jones K, Linardopoulos S, Workman P, Aherne W, Lord CJ, Ashworth A (2008) A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D. Oncogene 27: 1036-1044
-
(2008)
Oncogene
, vol.27
, pp. 1036-1044
-
-
Rayter, S.1
Elliott, R.2
Travers, J.3
Rowlands, M.G.4
Richardson, T.B.5
Boxall, K.6
Jones, K.7
Linardopoulos, S.8
Workman, P.9
Aherne, W.10
Lord, C.J.11
Ashworth, A.12
-
39
-
-
0034142034
-
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phos-phorylate p53 at multiple DNA damage-inducible sites
-
Shieh SY, Ahn J, Tamai K, Taya Y, Prives C (2000) The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phos-phorylate p53 at multiple DNA damage-inducible sites. Genes Dev 14: 289-300
-
(2000)
Genes Dev
, vol.14
, pp. 289-300
-
-
Shieh, S.Y.1
Ahn, J.2
Tamai, K.3
Taya, Y.4
Prives, C.5
-
40
-
-
38649118240
-
Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression
-
Shimada M, Niida H, Zineldeen DH, Tagami H, Tanaka M, Saito H, Nakanishi M (2008) Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression. Cell 132: 221-232
-
(2008)
Cell
, vol.132
, pp. 221-232
-
-
Shimada, M.1
Niida, H.2
Zineldeen, D.H.3
Tagami, H.4
Tanaka, M.5
Saito, H.6
Nakanishi, M.7
-
41
-
-
33748150967
-
Wip1 phosphatase modulates ATM-dependent signaling pathways
-
Shreeram S, Demidov ON, Hee WK, Yamaguchi H, Onishi N, Kek C, Timofeev ON, Dudgeon C, Fornace AJ, Anderson CW, Minami Y, Appella E, Bulavin DV (2006a) Wip1 phosphatase modulates ATM-dependent signaling pathways. Mol Cell 23: 757-764
-
(2006)
Mol Cell
, vol.23
, pp. 757-764
-
-
Shreeram, S.1
Demidov, O.N.2
Hee, W.K.3
Yamaguchi, H.4
Onishi, N.5
Kek, C.6
Timofeev, O.N.7
Dudgeon, C.8
Fornace, A.J.9
Anderson, C.W.10
Minami, Y.11
Appella, E.12
Bulavin, D.V.13
-
42
-
-
33845893896
-
Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase
-
Shreeram S, Hee WK, Demidov ON, Kek C, Yamaguchi H, Fornace AJ, Anderson CW, Appella E, Bulavin DV (2006b) Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase. J Exp Med 203: 2793-2799
-
(2006)
J Exp Med
, vol.203
, pp. 2793-2799
-
-
Shreeram, S.1
Hee, W.K.2
Demidov, O.N.3
Kek, C.4
Yamaguchi, H.5
Fornace, A.J.6
Anderson, C.W.7
Appella, E.8
Bulavin, D.V.9
-
43
-
-
0034282252
-
Polo-like kinase-1 is a target of the DNA damage checkpoint
-
Smits VAJ, Klompmaker R, Arnaud L, Rijksen G, Nigg EA, Medema RH (2000) Polo-like kinase-1 is a target of the DNA damage checkpoint. Nat Cell Biol 2: 672-676
-
(2000)
Nat Cell Biol
, vol.2
, pp. 672-676
-
-
Smits, V.A.J.1
Klompmaker, R.2
Arnaud, L.3
Rijksen, G.4
Nigg, E.A.5
Medema, R.H.6
-
45
-
-
33748752327
-
Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression
-
Spurgers KB, Gold DL, Coombes KR, Bohnenstiehl NL, Mullins B, Meyn RE, Logothetis CJ, McDonnell TJ (2006) Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression. J Biol Chem 281: 25134-25142
-
(2006)
J Biol Chem
, vol.281
, pp. 25134-25142
-
-
Spurgers, K.B.1
Gold, D.L.2
Coombes, K.R.3
Bohnenstiehl, N.L.4
Mullins, B.5
Meyn, R.E.6
Logothetis, C.J.7
McDonnell, T.J.8
-
46
-
-
33746922381
-
The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation
-
Tabach Y, Milyavsky M, Shats I, Brosh R, Zuk O, Yitzhaky A, Mantovani R, Domany E, Rotter V, Pilpel Y (2005) The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation Mol Syst Biol 1 2005 0022
-
(2005)
Mol Syst Biol
, vol.1
, pp. 0022
-
-
Tabach, Y.1
Milyavsky, M.2
Shats, I.3
Brosh, R.4
Zuk, O.5
Yitzhaky, A.6
Mantovani, R.7
Domany, E.8
Rotter, V.9
Pilpel, Y.10
-
47
-
-
0034383398
-
P53-inducible Wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation
-
Takekawa M, Adachi M, Nakahata A, Nakayama I, Itoh F, Tsukuda H, Taya Y, Imai K (2000) p53-inducible Wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation. EMBO J 19: 6517-6526
-
(2000)
EMBO J
, vol.19
, pp. 6517-6526
-
-
Takekawa, M.1
Adachi, M.2
Nakahata, A.3
Nakayama, I.4
Itoh, F.5
Tsukuda, H.6
Taya, Y.7
Imai, K.8
-
48
-
-
0035810054
-
Regulation of the G2/M transition by p53
-
Taylor WR, Stark GR (2001) Regulation of the G2/M transition by p53. Oncogene 20: 1803-1815
-
(2001)
Oncogene
, vol.20
, pp. 1803-1815
-
-
Taylor, W.R.1
Stark, G.R.2
-
49
-
-
58849146288
-
Distinct mechanisms act in concert to mediate cell cycle arrest
-
Toettcher JE, Loewer A, Ostheimer GJ, Yaffe MB, Tidor B, Lahav G (2009) Distinct mechanisms act in concert to mediate cell cycle arrest. Proc Natl Acad Sci USA 106: 785-790
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 785-790
-
-
Toettcher, J.E.1
Loewer, A.2
Ostheimer, G.J.3
Yaffe, M.B.4
Tidor, B.5
Lahav, G.6
-
50
-
-
4444321565
-
Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells
-
Van Vugt M, Bras A, Medema RH (2004) Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells. Mol Cell 15: 799-811
-
(2004)
Mol Cell
, vol.15
, pp. 799-811
-
-
Van Vugt, M.1
Bras, A.2
Medema, R.H.3
-
51
-
-
0035985177
-
Identification of genes periodically expressed in the human cell cycle and their expression in tumors
-
Whitfield ML, Sherlock G, Saldanha AJ, Murray JI, Ball CA, Alexander KE, Matese JC, Perou CM, Hurt MM, Brown PO, Botstein D (2002) Identification of genes periodically expressed in the human cell cycle and their expression in tumors. Mol Biol Cell 13: 1977-2000
-
(2002)
Mol Biol Cell
, vol.13
, pp. 1977-2000
-
-
Whitfield, M.L.1
Sherlock, G.2
Saldanha, A.J.3
Murray, J.I.4
Ball, C.A.5
Alexander, K.E.6
Matese, J.C.7
Perou, C.M.8
Hurt, M.M.9
Brown, P.O.10
Botstein, D.11
-
52
-
-
35948959950
-
The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases
-
Yamaguchi H, Durell SR, Chatterjee DK, Anderson CW, Appella E (2007) The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases. Biochemistry 46: 12594-12603
-
(2007)
Biochemistry
, vol.46
, pp. 12594-12603
-
-
Yamaguchi, H.1
Durell, S.R.2
Chatterjee, D.K.3
Anderson, C.W.4
Appella, E.5
-
53
-
-
67649631304
-
Wip1 regulates the generation of new neural cells in the adult olfactory bulb through p53-dependent cell cycle control
-
Zhu YH, Zhang CW, Lu L, Demidov ON, Sun L, Yang L, Bulavin DV, Xiao ZC (2009) Wip1 regulates the generation of new neural cells in the adult olfactory bulb through p53-dependent cell cycle control. Stem Cells 27: 1433-1442
-
(2009)
Stem Cells
, vol.27
, pp. 1433-1442
-
-
Zhu, Y.H.1
Zhang, C.W.2
Lu, L.3
Demidov, O.N.4
Sun, L.5
Yang, L.6
Bulavin, D.V.7
Xiao, Z.C.8
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