-
1
-
-
79952235291
-
Dynamics of DNA damage response proteins at DNA breaks: A focus on protein modifications
-
Polo,S.E. and Jackson,S.P. (2011) Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev., 25, 409-433.
-
(2011)
Genes Dev.
, vol.25
, pp. 409-433
-
-
Polo, S.E.1
Jackson, S.P.2
-
2
-
-
39749118612
-
The gamma-H2A.X: Is it just a surrogate marker of double-strand breaks or much more?
-
DOI 10.1002/em.20358
-
Ismail,I.H. and Hendzel,M.J. (2008) The gamma-H2A.X: Is it just a surrogate marker of double-strand breaks or much more? Environ. Mol. Mutagen., 49, 73-82. (Pubitemid 351293013)
-
(2008)
Environmental and Molecular Mutagenesis
, vol.49
, Issue.1
, pp. 73-82
-
-
Ismail, I.H.1
Hendzel, M.J.2
-
3
-
-
77957748289
-
BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair
-
Ismail,I.H., Andrin,C., McDonald,D. and Hendzel,M.J. (2010) BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair. J. Cell. Biol., 191, 45-60.
-
(2010)
J. Cell. Biol.
, vol.191
, pp. 45-60
-
-
Ismail, I.H.1
Andrin, C.2
McDonald, D.3
Hendzel, M.J.4
-
4
-
-
79956086415
-
BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair
-
Ginjala,V., Nacerddine,K., Kulkarni,A., Oza,J., Hill,S.J., Yao,M., Citterio,E., van Lohuizen,M. and Ganesan,S. (2011) BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair. Mol. Cell. Biol., 31, 1972-1982.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 1972-1982
-
-
Ginjala, V.1
Nacerddine, K.2
Kulkarni, A.3
Oza, J.4
Hill, S.J.5
Yao, M.6
Citterio, E.7
Van Lohuizen, M.8
Ganesan, S.9
-
5
-
-
36749084931
-
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
-
DOI 10.1126/science.1150034
-
Kolas,N.K., Chapman,J.R., Nakada,S., Ylanko,J., Chahwan,R., Sweeney,F.D., Panier,S., Mendez,M., Wildenhain,J., Thomson,T.M. et al. (2007) Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science, 318, 1637-1640. (Pubitemid 350233664)
-
(2007)
Science
, vol.318
, Issue.5856
, pp. 1637-1640
-
-
Kolas, N.K.1
Chapman, J.R.2
Nakada, S.3
Ylanko, J.4
Chahwan, R.5
Sweeney, F.D.6
Panier, S.7
Mendez, M.8
Wildenhain, J.9
Thomson, T.M.10
Pelletier, L.11
Jackson, S.P.12
Durocher, D.13
-
6
-
-
36249031962
-
RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly
-
DOI 10.1016/j.cell.2007.09.041, PII S0092867407012706
-
Huen,M.S., Grant,R., Manke,I., Minn,K., Yu,X., Yaffe,M.B. and Chen,J. (2007) RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell, 131, 901-914. (Pubitemid 350138083)
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 901-914
-
-
Huen, M.S.Y.1
Grant, R.2
Manke, I.3
Minn, K.4
Yu, X.5
Yaffe, M.B.6
Chen, J.7
-
7
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil,C., Mailand,N., Bekker-Jensen,S., Menard,P., Larsen,D.H., Pepperkok,R., Ellenberg,J., Panier,S., Durocher,D., Bartek,J. et al. (2009) RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell, 136, 435-446.
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Doil, C.1
Mailand, N.2
Bekker-Jensen, S.3
Menard, P.4
Larsen, D.H.5
Pepperkok, R.6
Ellenberg, J.7
Panier, S.8
Durocher, D.9
Bartek, J.10
-
8
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
Stewart,G.S., Panier,S., Townsend,K., Al-Hakim,A.K., Kolas,N.K., Miller,E.S., Nakada,S., Ylanko,J., Olivarius,S., Mendez,M. et al. (2009) The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell, 136, 420-434.
-
(2009)
Cell
, vol.136
, pp. 420-434
-
-
Stewart, G.S.1
Panier, S.2
Townsend, K.3
Al-Hakim, A.K.4
Kolas, N.K.5
Miller, E.S.6
Nakada, S.7
Ylanko, J.8
Olivarius, S.9
Mendez, M.10
-
9
-
-
36248966246
-
RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins
-
DOI 10.1016/j.cell.2007.09.040, PII S0092867407012718
-
Mailand,N., Bekker-Jensen,S., Faustrup,H., Melander,F., Bartek,J., Lukas,C. and Lukas,J. (2007) RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell, 131, 887-900. (Pubitemid 350138084)
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
Lukas, C.6
Lukas, J.7
-
10
-
-
78649492271
-
The ubiquitous role of ubiquitin in the DNA damage response
-
Al-Hakim,A., Escribano-Diaz,C., Landry,M.C., O'Donnell,L., Panier,S., Szilard,R.K. and Durocher,D. (2010) The ubiquitous role of ubiquitin in the DNA damage response. DNA Repair, 9, 1229-1240.
-
(2010)
DNA Repair
, vol.9
, pp. 1229-1240
-
-
Al-Hakim, A.1
Escribano-Diaz, C.2
Landry, M.C.3
O'Donnell, L.4
Panier, S.5
Szilard, R.K.6
Durocher, D.7
-
11
-
-
79952633107
-
Polycomb group proteins in the DNA damage response: A link between radiation resistance and "stemness"
-
Gieni,R.S., Ismail,I.H., Campbell,S. and Hendzel,M.J. (2011) Polycomb group proteins in the DNA damage response: a link between radiation resistance and "stemness". Cell Cycle, 10, 883-894.
-
(2011)
Cell Cycle
, vol.10
, pp. 883-894
-
-
Gieni, R.S.1
Ismail, I.H.2
Campbell, S.3
Hendzel, M.J.4
-
12
-
-
63049101044
-
Regulatory ubiquitylation in response to DNA double-strand breaks
-
Panier,S. and Durocher,D. (2009) Regulatory ubiquitylation in response to DNA double-strand breaks. DNA Repair, 8, 436-443.
-
(2009)
DNA Repair
, vol.8
, pp. 436-443
-
-
Panier, S.1
Durocher, D.2
-
13
-
-
80052765356
-
SUMOylation and de-SUMOylation in response to DNA damage
-
Dou,H., Huang,C., Van Nguyen,T., Lu,L.S. and Yeh,E.T. (2011) SUMOylation and de-SUMOylation in response to DNA damage. FEBS Lett., 585, 2891-2896.
-
(2011)
FEBS Lett.
, vol.585
, pp. 2891-2896
-
-
Dou, H.1
Huang, C.2
Van Nguyen, T.3
Lu, L.S.4
Yeh, E.T.5
-
14
-
-
63649144413
-
Principles of ubiquitin and SUMO modifications in DNA repair
-
Bergink,S. and Jentsch,S. (2009) Principles of ubiquitin and SUMO modifications in DNA repair. Nature, 458, 461-467.
-
(2009)
Nature
, vol.458
, pp. 461-467
-
-
Bergink, S.1
Jentsch, S.2
-
15
-
-
41149094512
-
Regulation of DNA repair throughout the cell cycle
-
DOI 10.1038/nrm2351, PII NRM2351
-
Branzei,D. and Foiani,M. (2008) Regulation of DNA repair throughout the cell cycle. Nature Rev. Mol. Cell. Biol., 9, 297-308. (Pubitemid 351430844)
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.4
, pp. 297-308
-
-
Branzei, D.1
Foiani, M.2
-
16
-
-
15944406765
-
SUMO: A history of modification
-
Hay,R.T. (2005) SUMO: a history of modification. Mol. Cell, 18, 1-12.
-
(2005)
Mol. Cell
, vol.18
, pp. 1-12
-
-
Hay, R.T.1
-
17
-
-
37749006669
-
Signalling pathways and the regulation of SUMO modification
-
Guo,B., Yang,S.H., Witty,J. and Sharrocks,A.D. (2007) Signalling pathways and the regulation of SUMO modification. Biochem. Soc. Trans., 35, 1414-1418.
-
(2007)
Biochem. Soc. Trans.
, vol.35
, pp. 1414-1418
-
-
Guo, B.1
Yang, S.H.2
Witty, J.3
Sharrocks, A.D.4
-
18
-
-
0033537828
-
Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1
-
Desterro,J.M., Rodriguez,M.S., Kemp,G.D. and Hay,R.T. (1999) Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1. J. Biol. Chem., 274, 10618-10624.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10618-10624
-
-
Desterro, J.M.1
Rodriguez, M.S.2
Kemp, G.D.3
Hay, R.T.4
-
19
-
-
0033060826
-
Molecular cloning and characterization of human AOS1 and UBA2, components of the sentrin-activating enzyme complex
-
DOI 10.1016/S0014-5793(99)00367-1, PII S0014579399003671
-
Gong,L., Li,B., Millas,S. and Yeh,E.T. (1999) Molecular cloning and characterization of human AOS1 and UBA2, components of the sentrin-activating enzyme complex. FEBS Lett., 448, 185-189. (Pubitemid 29151657)
-
(1999)
FEBS Letters
, vol.448
, Issue.1
, pp. 185-189
-
-
Gong, L.1
Li, B.2
Millas, S.3
Yeh, E.T.H.4
-
20
-
-
0030794729
-
The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer
-
DOI 10.1093/emboj/16.18.5509
-
Johnson,E.S., Schwienhorst,I., Dohmen,R.J. and Blobel,G. (1997) The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J., 16, 5509-5519. (Pubitemid 27399843)
-
(1997)
EMBO Journal
, vol.16
, Issue.18
, pp. 5509-5519
-
-
Johnson, E.S.1
Schwienhorst, I.2
Dohmen, R.J.3
Blobel, G.4
-
21
-
-
0033608252
-
In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2
-
DOI 10.1006/bbrc.1998.9995
-
Okuma,T., Honda,R., Ichikawa,G., Tsumagari,N. and Yasuda,H. (1999) In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2. Biochem. Biophys. Res. Commun., 254, 693-698. (Pubitemid 29290530)
-
(1999)
Biochemical and Biophysical Research Communications
, vol.254
, Issue.3
, pp. 693-698
-
-
Okuma, T.1
Honda, R.2
Ichikawa, G.3
Tsumagari, N.4
Yasuda, H.5
-
22
-
-
0037418829
-
The polycomb protein Pc2 is a SUMO E3
-
DOI 10.1016/S0092-8674(03)00159-4
-
Kagey,M.H., Melhuish,T.A. and Wotton,D. (2003) The polycomb protein Pc2 is a SUMO E3. Cell, 113, 127-137. (Pubitemid 36411965)
-
(2003)
Cell
, vol.113
, Issue.1
, pp. 127-137
-
-
Kagey, M.H.1
Melhuish, T.A.2
Wotton, D.3
-
23
-
-
79952846685
-
SUMO losing balance: SUMO proteases disrupt SUMO homeostasis to facilitate cancer development and progression
-
Bawa-Khalfe,T. and Yeh,E.T. (2010) SUMO losing balance: SUMO proteases disrupt SUMO homeostasis to facilitate cancer development and progression. Genes Cancer, 1, 748-752.
-
(2010)
Genes Cancer
, vol.1
, pp. 748-752
-
-
Bawa-Khalfe, T.1
Yeh, E.T.2
-
24
-
-
0036291475
-
PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases
-
DOI 10.1128/MCB.22.14.5222-5234.2002
-
Kotaja,N., Karvonen,U., Janne,O.A. and Palvimo,J.J. (2002) PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases. Mol. Cell. Biol., 22, 5222-5234. (Pubitemid 34700711)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.14
, pp. 5222-5234
-
-
Kotaja, N.1
Karvonen, U.2
Janne, O.A.3
Palvimo, J.J.4
-
25
-
-
0037059619
-
The nucleoporin RanBP2 has SUMO1 E3 ligase activity
-
DOI 10.1016/S0092-8674(01)00633-X
-
Pichler,A., Gast,A., Seeler,J.S., Dejean,A. and Melchior,F. (2002) The nucleoporin RanBP2 has SUMO1 E3 ligase activity. Cell, 108, 109-120. (Pubitemid 34137016)
-
(2002)
Cell
, vol.108
, Issue.1
, pp. 109-120
-
-
Pichler, A.1
Gast, A.2
Seeler, J.S.3
Dejean, A.4
Melchior, F.5
-
26
-
-
0035576878
-
PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies
-
DOI 10.1101/gad.944801
-
Sachdev,S., Bruhn,L., Sieber,H., Pichler,A., Melchior,F. and Grosschedl,R. (2001) PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies. Genes Dev., 15, 3088-3103. (Pubitemid 33115674)
-
(2001)
Genes and Development
, vol.15
, Issue.23
, pp. 3088-3103
-
-
Sachdev, S.1
Bruhn, L.2
Sieber, H.3
Pichler, A.4
Melchior, F.5
Grosschedl, R.6
-
27
-
-
0036532114
-
Programming off and on states in chromatin: Mechanisms of Polycomb and trithorax group complexes
-
DOI 10.1016/S0959-437X(02)00288-5
-
Simon,J.A. and Tamkun,J.W. (2002) Programming off and on states in chromatin: mechanisms of Polycomb and trithorax group complexes. Curr. Opin. Genet. Dev., 12, 210-218. (Pubitemid 34219494)
-
(2002)
Current Opinion in Genetics and Development
, vol.12
, Issue.2
, pp. 210-218
-
-
Simon, J.A.1
Tamkun, J.W.2
-
28
-
-
70349696541
-
Polycomb group protein gene silencing, non-coding RNA, stem cells, and cancer
-
Gieni,R.S. and Hendzel,M.J. (2009) Polycomb group protein gene silencing, non-coding RNA, stem cells, and cancer. Biochem Cell Biol, 87, 711-746.
-
(2009)
Biochem Cell Biol
, vol.87
, pp. 711-746
-
-
Gieni, R.S.1
Hendzel, M.J.2
-
29
-
-
72449175818
-
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
-
Galanty,Y., Belotserkovskaya,R., Coates,J., Polo,S., Miller,K.M. and Jackson,S.P. (2009) Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. Nature, 462, 935-939.
-
(2009)
Nature
, vol.462
, pp. 935-939
-
-
Galanty, Y.1
Belotserkovskaya, R.2
Coates, J.3
Polo, S.4
Miller, K.M.5
Jackson, S.P.6
-
30
-
-
72449163470
-
The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress
-
Morris,J.R., Boutell,C., Keppler,M., Densham,R., Weekes,D., Alamshah,A., Butler,L., Galanty,Y., Pangon,L., Kiuchi,T. et al. (2009) The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress. Nature, 462, 886-890.
-
(2009)
Nature
, vol.462
, pp. 886-890
-
-
Morris, J.R.1
Boutell, C.2
Keppler, M.3
Densham, R.4
Weekes, D.5
Alamshah, A.6
Butler, L.7
Galanty, Y.8
Pangon, L.9
Kiuchi, T.10
-
31
-
-
38149057387
-
PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites
-
Haince,J.F., McDonald,D., Rodrigue,A., Dery,U., Masson,J.Y., Hendzel,M.J. and Poirier,G.G. (2008) PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites. J. Biol. Chem., 283, 1197-1208.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 1197-1208
-
-
Haince, J.F.1
McDonald, D.2
Rodrigue, A.3
Dery, U.4
Masson, J.Y.5
Hendzel, M.J.6
Poirier, G.G.7
-
32
-
-
15844371219
-
Structural basis for 5' -end-specific recognition of guide RNA by the A. fulgidus Piwi protein
-
DOI 10.1038/nature03514
-
Ma,J.B., Yuan,Y.R., Meister,G., Pei,Y., Tuschl,T. and Patel,D.J. (2005) Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature, 434, 666-670. (Pubitemid 40488561)
-
(2005)
Nature
, vol.434
, Issue.7033
, pp. 666-670
-
-
Ma, J.-B.1
Yuan, Y.-R.2
Meister, G.3
Pei, Y.4
Tuschl, T.5
Patel, D.J.6
-
33
-
-
0030797708
-
Recombinant ATM protein complements the cellular A-T phenotype
-
Ziv,Y., Bar-Shira,A., Pecker,I., Russell,P., Jorgensen,T.J., Tsarfati,I. and Shiloh,Y. (1997) Recombinant ATM protein complements the cellular A-T phenotype. Oncogene, 15, 159-167. (Pubitemid 27344555)
-
(1997)
Oncogene
, vol.15
, Issue.2
, pp. 159-167
-
-
Ziv, Y.1
Bar-Shira, A.2
Pecker, I.3
Russell, P.4
Jorgensen, T.J.5
Tsarfati, I.6
Shiloh, Y.7
-
34
-
-
0028937877
-
Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line
-
Lees-Miller,S.P., Godbout,R., Chan,D.W., Weinfeld,M., Day,R.S. 3rd, Barron,G.M. and Allalunis-Turner,J. (1995) Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line. Science, 267, 1183-1185.
-
(1995)
Science
, vol.267
, pp. 1183-1185
-
-
Lees-Miller, S.P.1
Godbout, R.2
Chan, D.W.3
Weinfeld, M.4
Day III, R.S.5
Barron, G.M.6
Allalunis-Turner, J.7
-
35
-
-
0038641860
-
A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins
-
DOI 10.1042/BJ20021675
-
Gagne,J.P., Hunter,J.M., Labrecque,B., Chabot,B. and Poirier,G.G. (2003) A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins. Biochem. J., 371, 331-340. (Pubitemid 36547615)
-
(2003)
Biochemical Journal
, vol.371
, Issue.2
, pp. 331-340
-
-
Gagne, J.-P.1
Hunter, J.M.2
Labrecque, B.3
Chabot, B.4
Poirier, G.G.5
-
36
-
-
1342343930
-
SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization
-
DOI 10.1038/sj.onc.1207303
-
Ismail,I.H., Martensson,S., Moshinsky,D., Rice,A., Tang,C., Howlett,A., McMahon,G. and Hammarsten,O. (2004) SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization. Oncogene, 23, 873-882. (Pubitemid 38250932)
-
(2004)
Oncogene
, vol.23
, Issue.4
, pp. 873-882
-
-
Ismail, I.H.1
Martensson, S.2
Moshinsky, D.3
Rice, A.4
Tang, C.5
Howlett, A.6
McMahon, G.7
Hammarsten, O.8
-
37
-
-
30444445118
-
Interplay between human DNA repair proteins at a unique double-strand break in vivo
-
DOI 10.1038/sj.emboj.7600914, PII 7600914
-
Rodrigue,A., Lafrance,M., Gauthier,M.C., McDonald,D., Hendzel,M., West,S.C., Jasin,M. and Masson,J.Y. (2006) Interplay between human DNA repair proteins at a unique double-strand break in vivo. EMBO J., 25, 222-231. (Pubitemid 43077310)
-
(2006)
EMBO Journal
, vol.25
, Issue.1
, pp. 222-231
-
-
Rodrigue, A.1
Lafrance, M.2
Gauthier, M.-C.3
McDonald, D.4
Hendzel, M.5
West, S.C.6
Jasin, M.7
Masson, J.-Y.8
-
38
-
-
78649349810
-
A chromatin localization screen reveals poly (ADP ribose)- regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
-
Chou,D.M., Adamson,B., Dephoure,N.E., Tan,X., Nottke,A.C., Hurov,K.E., Gygi,S.P., Colaiacovo,M.P. and Elledge,S.J. (2010) A chromatin localization screen reveals poly (ADP ribose)- regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage. Proc. Natl Acad. Sci. USA, 107, 18475-18480.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 18475-18480
-
-
Chou, D.M.1
Adamson, B.2
Dephoure, N.E.3
Tan, X.4
Nottke, A.C.5
Hurov, K.E.6
Gygi, S.P.7
Colaiacovo, M.P.8
Elledge, S.J.9
-
39
-
-
80051494784
-
Monoubiquitination of H2AX protein regulates DNA damage response signaling
-
Pan,M.R., Peng,G., Hung,W.C. and Lin,S.Y. (2011) Monoubiquitination of H2AX protein regulates DNA damage response signaling. J. Biol. Chem., 286, 28599-28607.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 28599-28607
-
-
Pan, M.R.1
Peng, G.2
Hung, W.C.3
Lin, S.Y.4
-
40
-
-
33749058094
-
Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2
-
Roscic,A., Moller,A., Calzado,M.A., Renner,F., Wimmer,V.C., Gresko,E., Ludi,K.S. and Schmitz,M.L. (2006) Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2. Mol. Cell, 24, 77-89.
-
(2006)
Mol. Cell
, vol.24
, pp. 77-89
-
-
Roscic, A.1
Moller, A.2
Calzado, M.A.3
Renner, F.4
Wimmer, V.C.5
Gresko, E.6
Ludi, K.S.7
Schmitz, M.L.8
-
41
-
-
77955381770
-
BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery
-
Facchino,S., Abdouh,M., Chatoo,W. and Bernier,G. (2010) BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery. J. Neurosci.e, 30, 10096-10111.
-
(2010)
J. Neurosci.e
, vol.30
, pp. 10096-10111
-
-
Facchino, S.1
Abdouh, M.2
Chatoo, W.3
Bernier, G.4
-
42
-
-
67349156082
-
Bmi1 regulates mitochondrial function and the DNA damage response pathway
-
Liu,J., Cao,L., Chen,J., Song,S., Lee,I.H., Quijano,C., Liu,H., Keyvanfar,K., Chen,H., Cao,L.Y. et al. (2009) Bmi1 regulates mitochondrial function and the DNA damage response pathway. Nature, 459, 387-392.
-
(2009)
Nature
, vol.459
, pp. 387-392
-
-
Liu, J.1
Cao, L.2
Chen, J.3
Song, S.4
Lee, I.H.5
Quijano, C.6
Liu, H.7
Keyvanfar, K.8
Chen, H.9
Cao, L.Y.10
-
43
-
-
79955076992
-
An anticlastogenic function for the Polycomb Group gene Bmi1
-
Chagraoui,J., Hebert,J., Girard,S. and Sauvageau,G. (2011) An anticlastogenic function for the Polycomb Group gene Bmi1. Proc. Natl Acad. Sci. USA, 108, 5284-5289.
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 5284-5289
-
-
Chagraoui, J.1
Hebert, J.2
Girard, S.3
Sauvageau, G.4
-
44
-
-
55949121452
-
Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences
-
Vincenz,C. and Kerppola,T.K. (2008) Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences. Proc. Natl Acad. Sci. USA, 105, 16572-16577.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 16572-16577
-
-
Vincenz, C.1
Kerppola, T.K.2
-
45
-
-
77956526559
-
PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway
-
Krishnakumar,R. and Kraus,W.L. (2010) PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway. Mol. Cell, 39, 736-749.
-
(2010)
Mol. Cell
, vol.39
, pp. 736-749
-
-
Krishnakumar, R.1
Kraus, W.L.2
-
46
-
-
34447548569
-
Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents
-
DOI 10.1074/jbc.M608406200
-
Haince,J.F., Kozlov,S., Dawson,V.L., Dawson,T.M., Hendzel,M.J., Lavin,M.F. and Poirier,G.G. (2007) Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents. J. Biol. Chem., 282, 16441-16453. (Pubitemid 47100334)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.22
, pp. 16441-16453
-
-
Haince, J.-F.1
Kozlov, S.2
Dawson, V.L.3
Dawson, T.M.4
Hendzel, M.J.5
Lavin, M.F.6
Poirier, G.G.7
-
47
-
-
19944418213
-
Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality
-
DOI 10.1073/pnas.0406182101
-
Koh,D.W., Lawler,A.M., Poitras,M.F., Sasaki,M., Wattler,S., Nehls,M.C., Stoger,T., Poirier,G.G., Dawson,V.L. and Dawson,T.M. (2004) Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality. Proc. Natl Acad. Sci. USA, 101, 17699-17704. (Pubitemid 40051949)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.51
, pp. 17699-17704
-
-
Koh, D.W.1
Lawler, A.M.2
Poitras, M.F.3
Sasaki, M.4
Wattler, S.5
Nehls, M.C.6
Stoger, T.7
Poirier, G.G.8
Dawson, V.L.9
Dawson, T.M.10
-
48
-
-
61849091444
-
Proteomic investigation of phosphorylation sites in poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase
-
Gagne,J.P., Moreel,X., Gagne,P., Labelle,Y., Droit,A., Chevalier-Pare,M., Bourassa,S., McDonald,D., Hendzel,M.J., Prigent,C. et al. (2009) Proteomic investigation of phosphorylation sites in poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase. J. Proteome Res., 8, 1014-1029.
-
(2009)
J. Proteome Res.
, vol.8
, pp. 1014-1029
-
-
Gagne, J.P.1
Moreel, X.2
Gagne, P.3
Labelle, Y.4
Droit, A.5
Chevalier-Pare, M.6
Bourassa, S.7
McDonald, D.8
Hendzel, M.J.9
Prigent, C.10
-
49
-
-
0032504021
-
Structure determination of the small ubiquitin-related modifier SUMO-1
-
DOI 10.1006/jmbi.1998.1839
-
Bayer,P., Arndt,A., Metzger,S., Mahajan,R., Melchior,F., Jaenicke,R. and Becker,J. (1998) Structure determination of the small ubiquitin-related modifier SUMO-1. J. Mol. Biol., 280, 275-286. (Pubitemid 28325519)
-
(1998)
Journal of Molecular Biology
, vol.280
, Issue.2
, pp. 275-286
-
-
Bayer, P.1
Arndt, A.2
Metzger, S.3
Mahajan, R.4
Melchior, F.5
Jaenicke, R.6
Becker, J.7
-
50
-
-
0036830642
-
Role of histone H3 lysine 27 methylation in polycomb-group silencing
-
DOI 10.1126/science.1076997
-
Cao,R., Wang,L., Wang,H., Xia,L., Erdjument-Bromage,H., Tempst,P., Jones,R.S. and Zhang,Y. (2002) Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science, 298, 1039-1043. (Pubitemid 35247314)
-
(2002)
Science
, vol.298
, Issue.5595
, pp. 1039-1043
-
-
Cao, R.1
Wang, L.2
Wang, H.3
Xia, L.4
Erdjument-Bromage, H.5
Tempst, P.6
Jones, R.S.7
Zhang, Y.8
-
51
-
-
0043127085
-
Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by polycomb and HP1 chromodomains
-
DOI 10.1101/gad.1110503
-
Fischle,W., Wang,Y., Jacobs,S.A., Kim,Y., Allis,C.D. and Khorasanizadeh,S. (2003) Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains. Genes Dev., 17, 1870-1881. (Pubitemid 36944564)
-
(2003)
Genes and Development
, vol.17
, Issue.15
, pp. 1870-1881
-
-
Fischle, W.1
Wang, Y.2
Jacobs, S.A.3
Kim, Y.4
Allis, C.D.5
Khorasanizadeh, S.6
-
52
-
-
0041624288
-
Structural basis for specific binding of polycomb chromodomain to histone H3 methylated at Lys 27
-
DOI 10.1101/gad.269603
-
Min,J., Zhang,Y. and Xu,R.M. (2003) Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27. Genes Dev., 17, 1823-1828. (Pubitemid 36944559)
-
(2003)
Genes and Development
, vol.17
, Issue.15
, pp. 1823-1828
-
-
Min, J.1
Zhang, Y.2
Xu, R.-M.3
-
53
-
-
0028201742
-
Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the BMI1 proto-oncogene
-
van der Lugt,N.M., Domen,J., Linders,K., van Roon,M., Robanus-Maandag,E., te Riele,H., van der Valk,M., Deschamps,J., Sofroniew,M., van Lohuizen,M. et al. (1994) Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the BMI1 proto-oncogene. Genes Dev., 8, 757-769.
-
(1994)
Genes Dev.
, vol.8
, pp. 757-769
-
-
Van Der Lugt, N.M.1
Domen, J.2
Linders, K.3
Van Roon, M.4
Robanus-Maandag, E.5
Te Riele, H.6
Van Der Valk, M.7
Deschamps, J.8
Sofroniew, M.9
Van Lohuizen, M.10
-
54
-
-
3943099375
-
Protein modification by SUMO
-
Johnson,E.S. (2004) Protein modification by SUMO. Annual Rev. Biochem., 73, 355-382.
-
(2004)
Annual Rev. Biochem.
, vol.73
, pp. 355-382
-
-
Johnson, E.S.1
-
55
-
-
3242891383
-
PARP-1, PARP-2 and ATM in the DNA damage response: Functional synergy in mouse development
-
DOI 10.1016/j.dnarep.2004.06.002, PII S1568786404001764
-
Huber,A., Bai,P., de Murcia,J.M. and de Murcia,G. (2004) PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development. DNA Repair, 3, 1103-1108. (Pubitemid 38997953)
-
(2004)
DNA Repair
, vol.3
, Issue.8-9
, pp. 1103-1108
-
-
Huber, A.1
Bai, P.2
Murcia, J.M.D.3
Murcia, G.D.4
-
56
-
-
38149057387
-
PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites
-
Haince,J.F., McDonald,D., Rodrigue,A., Dery,U., Masson,J.Y., Hendzel,M.J. and Poirier,G.G. (2008) PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites. J. Biol. Chem., 283, 1197-1208.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 1197-1208
-
-
Haince, J.F.1
McDonald, D.2
Rodrigue, A.3
Dery, U.4
Masson, J.Y.5
Hendzel, M.J.6
Poirier, G.G.7
-
57
-
-
84856177800
-
Acetylation-dependent nuclear arrangement and recruitment of BMI1 protein to UV-damaged chromatin
-
Sustackova,G., Kozubek,S., Stixova,L., Legartova,S., Matula,P., Orlova,D. and Bartova,E. (2012) Acetylation-dependent nuclear arrangement and recruitment of BMI1 protein to UV-damaged chromatin. J. Cell. Physiol., 227, 1838-1850.
-
(2012)
J. Cell. Physiol.
, vol.227
, pp. 1838-1850
-
-
Sustackova, G.1
Kozubek, S.2
Stixova, L.3
Legartova, S.4
Matula, P.5
Orlova, D.6
Bartova, E.7
|