-
1
-
-
0037062492
-
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX
-
Bassing, C.H., K.F. Chua, J. Sekiguchi, H. Suh, S.R. Whitlow, J.C. Fleming, B.C. Monroe, D.N. Ciccone, C. Yan, K. Vlasakova, et al. 2002. Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX. Proc. Natl. Acad. Sci. USA. 99:8173-8178.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8173-8178
-
-
Bassing, C.H.1
Chua, K.F.2
Sekiguchi, J.3
Suh, H.4
Whitlow, S.R.5
Fleming, J.C.6
Monroe, B.C.7
Ciccone, D.N.8
Yan, C.9
Vlasakova, K.10
-
2
-
-
0020324991
-
Yeast centromere DNA is in a unique and highly ordered structure in chromosomes and small circular minichromosomes
-
Bloom, K.S., and J. Carbon. 1982. Yeast centromere DNA is in a unique and highly ordered structure in chromosomes and small circular minichromosomes. Cell. 29:305-317.
-
(1982)
Cell
, vol.29
, pp. 305-317
-
-
Bloom, K.S.1
Carbon, J.2
-
3
-
-
0035504409
-
Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction
-
Booth, C., E. Griffith, G. Brady, and D. Lydall. 2001. Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction. Nucleic Acids Res. 29:4414-4422.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 4414-4422
-
-
Booth, C.1
Griffith, E.2
Brady, G.3
Lydall, D.4
-
4
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
Celeste, A., S. Petersen, P.J. Romanienko, O. Fernandez-Capetillo, H.T. Chen, O.A. Sedelnikova, B. Reina-San-Martin, V. Coppola, E. Meffre, M.J. Difilippantonio, et al. 2002. Genomic instability in mice lacking histone H2AX. Science. 296:922-927.
-
(2002)
Science
, vol.296
, pp. 922-927
-
-
Celeste, A.1
Petersen, S.2
Romanienko, P.J.3
Fernandez-Capetillo, O.4
Chen, H.T.5
Sedelnikova, O.A.6
Reina-San-Martin, B.7
Coppola, V.8
Meffre, E.9
Difilippantonio, M.J.10
-
5
-
-
0037711771
-
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
-
Celeste, A., O. Fernandez-Capetillo, M.J. Kruhlak, D.R. Pilch, D.W. Staudt, A. Lee, R.F. Bonner, W.M. Bonner, and A. Nussenzweig. 2003. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat. Cell Biol. 5:675-679.
-
(2003)
Nat. Cell Biol
, vol.5
, pp. 675-679
-
-
Celeste, A.1
Fernandez-Capetillo, O.2
Kruhlak, M.J.3
Pilch, D.R.4
Staudt, D.W.5
Lee, A.6
Bonner, R.F.7
Bonner, W.M.8
Nussenzweig, A.9
-
6
-
-
0035928740
-
Altering telomere structure allows telomerase to act in yeast lacking ATM kinases
-
Chan, S.W., J. Chang, J. Prescott, and E.H. Blackburn. 2001. Altering telomere structure allows telomerase to act in yeast lacking ATM kinases. Curr. Biol. 11:1240-1250.
-
(2001)
Curr. Biol
, vol.11
, pp. 1240-1250
-
-
Chan, S.W.1
Chang, J.2
Prescott, J.3
Blackburn, E.H.4
-
7
-
-
33748199605
-
Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination
-
De Piccoli, G., F. Cortes-Ledesma, G. Ira, J. Torres-Rosell, S. Uhle, S. Farmer, J.Y. Hwang, F. Machin, A. Ceschia, A. McAleenan, et al. 2006. Smc5-Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination. Nat. Cell Biol. 8:1032-1034.
-
(2006)
Nat. Cell Biol
, vol.8
, pp. 1032-1034
-
-
De Piccoli, G.1
Cortes-Ledesma, F.2
Ira, G.3
Torres-Rosell, J.4
Uhle, S.5
Farmer, S.6
Hwang, J.Y.7
Machin, F.8
Ceschia, A.9
McAleenan, A.10
-
8
-
-
10944267160
-
Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites
-
Downs, J.A., S. Allard, O. Jobin-Robitaille, A. Javaheri, A. Auger, N. Bouchard, S.J. Kron, S.P. Jackson, and J. Cote. 2004. Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites. Mol. Cell. 16:979-990.
-
(2004)
Mol. Cell
, vol.16
, pp. 979-990
-
-
Downs, J.A.1
Allard, S.2
Jobin-Robitaille, O.3
Javaheri, A.4
Auger, A.5
Bouchard, N.6
Kron, S.J.7
Jackson, S.P.8
Cote, J.9
-
9
-
-
0141740426
-
Focusing on foci: H2AX and the recruitment of DNA-damage response factors
-
Fernandez-Capetillo, O., A. Celeste, and A. Nussenzweig. 2003. Focusing on foci: H2AX and the recruitment of DNA-damage response factors. Cell Cycle. 2:426-427.
-
(2003)
Cell Cycle
, vol.2
, pp. 426-427
-
-
Fernandez-Capetillo, O.1
Celeste, A.2
Nussenzweig, A.3
-
10
-
-
0038820065
-
Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes
-
Furuta, T., H. Takemura, Z.Y. Liao, G.J. Aune, C. Redon, O.A. Sedelnikova, D.R. Pilch, E.P. Rogakou, A. Celeste, H.T. Chen, et al. 2003. Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes. J. Biol. Chem. 278:20303-20312.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 20303-20312
-
-
Furuta, T.1
Takemura, H.2
Liao, Z.Y.3
Aune, G.J.4
Redon, C.5
Sedelnikova, O.A.6
Pilch, D.R.7
Rogakou, E.P.8
Celeste, A.9
Chen, H.T.10
-
11
-
-
0028822203
-
-
Garvik, B., M. Carson, and L. Hartwell. 1995. Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol. Cell. Biol. 15:6128-6138. (published erratum appears in Mol. Cell. Biol. 1996. 16:457).
-
Garvik, B., M. Carson, and L. Hartwell. 1995. Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol. Cell. Biol. 15:6128-6138. (published erratum appears in Mol. Cell. Biol. 1996. 16:457).
-
-
-
-
12
-
-
34547813672
-
-
Goudsouzian, L.K., C.T. Tuzon, and V.A. Zakian. 2006. S. cerevisiae Tel1p and Mre11p are required for normal levels of Est1p and Est2p telomere association. Mol. Cell. 24:603-610.
-
Goudsouzian, L.K., C.T. Tuzon, and V.A. Zakian. 2006. S. cerevisiae Tel1p and Mre11p are required for normal levels of Est1p and Est2p telomere association. Mol. Cell. 24:603-610.
-
-
-
-
13
-
-
0035502994
-
Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination
-
Grandin, N., C. Damon, and M. Charbonneau. 2001. Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination. EMBO J. 20:6127-6139.
-
(2001)
EMBO J
, vol.20
, pp. 6127-6139
-
-
Grandin, N.1
Damon, C.2
Charbonneau, M.3
-
14
-
-
33751419716
-
Surviving the breakup: The DNA damage checkpoint
-
Harrison, J.C., and J.E. Haber. 2006. Surviving the breakup: the DNA damage checkpoint. Annu. Rev. Genet. 40:209-235.
-
(2006)
Annu. Rev. Genet
, vol.40
, pp. 209-235
-
-
Harrison, J.C.1
Haber, J.E.2
-
15
-
-
7244220162
-
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
-
Ira, G., A. Pellicioli, A. Balijja, X. Wang, S. Fiorani, W. Carotenuto, G. Liberi, D. Bressan, L. Wan, N.M. Hollingsworth, et al. 2004. DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1. Nature. 431:1011-1017.
-
(2004)
Nature
, vol.431
, pp. 1011-1017
-
-
Ira, G.1
Pellicioli, A.2
Balijja, A.3
Wang, X.4
Fiorani, S.5
Carotenuto, W.6
Liberi, G.7
Bressan, D.8
Wan, L.9
Hollingsworth, N.M.10
-
16
-
-
31444445458
-
A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery
-
Keogh, M.C., J.A. Kim, M. Downey, J. Fillingham, D. Chowdhury, J.C. Harrison, M. Onishi, N. Datta, S. Galicia, A. Emili, et al. 2006. A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature. 439:497-501.
-
(2006)
Nature
, vol.439
, pp. 497-501
-
-
Keogh, M.C.1
Kim, J.A.2
Downey, M.3
Fillingham, J.4
Chowdhury, D.5
Harrison, J.C.6
Onishi, M.7
Datta, N.8
Galicia, S.9
Emili, A.10
-
18
-
-
33644905252
-
Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
-
Kruhlak, M.J., A. Celeste, G. Dellaire, O. Fernandez-Capetillo, W.G. Muller, J.G. McNally, D.P. Bazett-Jones, and A. Nussenzweig. 2006. Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks. J. Cell Biol. 172:823-834.
-
(2006)
J. Cell Biol
, vol.172
, pp. 823-834
-
-
Kruhlak, M.J.1
Celeste, A.2
Dellaire, G.3
Fernandez-Capetillo, O.4
Muller, W.G.5
McNally, J.G.6
Bazett-Jones, D.P.7
Nussenzweig, A.8
-
19
-
-
33644914709
-
The realtime polymerase chain reaction
-
Kubista, M., J.M. Andrade, M. Bengtsson, A. Forootan, J. Jonak, K. Lind, R. Sindelka, R. Sjoback, B. Sjogreen, L. Strombom, et al. 2006. The realtime polymerase chain reaction. Mol. Aspects Med. 27:95-125.
-
(2006)
Mol. Aspects Med
, vol.27
, pp. 95-125
-
-
Kubista, M.1
Andrade, J.M.2
Bengtsson, M.3
Forootan, A.4
Jonak, J.5
Lind, K.6
Sindelka, R.7
Sjoback, R.8
Sjogreen, B.9
Strombom, L.10
-
20
-
-
0034437899
-
Arrest, adaptation and recovery following a chromosome double-strand break in Saccharomyces cerevisiae
-
Lee, S., A. Pellicioli, J. Demeter, M. Vaze, A.P. Gasch, A. Malkova, P. Brown, T. Stearns, M. Foiani, and J.E. Haber. 2000. Arrest, adaptation and recovery following a chromosome double-strand break in Saccharomyces cerevisiae. Cold Spring Harb. Symp. Quant. Biol. 65:303-314.
-
(2000)
Cold Spring Harb. Symp. Quant. Biol
, vol.65
, pp. 303-314
-
-
Lee, S.1
Pellicioli, A.2
Demeter, J.3
Vaze, M.4
Gasch, A.P.5
Malkova, A.6
Brown, P.7
Stearns, T.8
Foiani, M.9
Haber, J.E.10
-
21
-
-
33745217560
-
Chromosomal association of the Smc5/6 complex reveals that it functions in differently regulated pathways
-
Lindroos, H.B., L. Strom, T. Itoh, Y. Katou, K. Shirahige, and C. Sjogren. 2006. Chromosomal association of the Smc5/6 complex reveals that it functions in differently regulated pathways. Mol. Cell. 22:755-767.
-
(2006)
Mol. Cell
, vol.22
, pp. 755-767
-
-
Lindroos, H.B.1
Strom, L.2
Itoh, T.3
Katou, Y.4
Shirahige, K.5
Sjogren, C.6
-
22
-
-
7744243520
-
The DNA damage response: Sensing and signaling
-
McGowan, C.H., and P. Russell. 2004. The DNA damage response: sensing and signaling. Curr. Opin. Cell Biol. 16:629-633.
-
(2004)
Curr. Opin. Cell Biol
, vol.16
, pp. 629-633
-
-
McGowan, C.H.1
Russell, P.2
-
23
-
-
0029976325
-
Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae
-
Moore, J.K., and J.E. Haber. 1996. Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:2164-2173.
-
(1996)
Mol. Cell. Biol
, vol.16
, pp. 2164-2173
-
-
Moore, J.K.1
Haber, J.E.2
-
24
-
-
10944224673
-
INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair
-
Morrison, A.J., J. Highland, N.J. Krogan, A. Arbel-Eden, J.F. Greenblatt, J.E. Haber, and X. Shen. 2004. INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell. 119:767-775.
-
(2004)
Cell
, vol.119
, pp. 767-775
-
-
Morrison, A.J.1
Highland, J.2
Krogan, N.J.3
Arbel-Eden, A.4
Greenblatt, J.F.5
Haber, J.E.6
Shen, X.7
-
25
-
-
33748272677
-
Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage
-
Papamichos-Chronakis, M., J.E. Krebs, and C.L. Peterson. 2006. Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage. Genes Dev. 20:2437-2449.
-
(2006)
Genes Dev
, vol.20
, pp. 2437-2449
-
-
Papamichos-Chronakis, M.1
Krebs, J.E.2
Peterson, C.L.3
-
26
-
-
2642516988
-
Recombination and the Tel1 and Mec1 checkpoints differentially effect genome rearrangements driven by telomere dysfunction in yeast
-
Pennaneach, V., and R.D. Kolodner. 2004. Recombination and the Tel1 and Mec1 checkpoints differentially effect genome rearrangements driven by telomere dysfunction in yeast. Nat. Genet. 36:612-617.
-
(2004)
Nat. Genet
, vol.36
, pp. 612-617
-
-
Pennaneach, V.1
Kolodner, R.D.2
-
27
-
-
0033499772
-
High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating-type locus HMRa
-
Ravindra, A., K. Weiss, and R.T. Simpson. 1999. High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating-type locus HMRa. Mol. Cell. Biol. 19:7944-7950.
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 7944-7950
-
-
Ravindra, A.1
Weiss, K.2
Simpson, R.T.3
-
28
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou, E.P., D.R. Pilch, A.H. Orr, V.S. Ivanova, and W.M. Bonner. 1998. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273:5858-5868.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
29
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
Rogakou, E.P., C. Boon, C. Redon, and W.M. Bonner. 1999. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 146:905-916.
-
(1999)
J. Cell Biol
, vol.146
, pp. 905-916
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
30
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh, Y. 2003. ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer. 3:155-168.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
31
-
-
4644257681
-
Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break
-
Shroff, R., A. Arbel-Eden, D. Pilch, G. Ira, W.M. Bonner, J.H. Petrini, J.E. Haber, and M. Lichten. 2004. Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break. Curr. Biol. 14:1703-1711.
-
(2004)
Curr. Biol
, vol.14
, pp. 1703-1711
-
-
Shroff, R.1
Arbel-Eden, A.2
Pilch, D.3
Ira, G.4
Bonner, W.M.5
Petrini, J.H.6
Haber, J.E.7
Lichten, M.8
-
32
-
-
10944232673
-
Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair
-
Strom, L., H.B. Lindroos, K. Shirahige, and C. Sjogren. 2004. Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair. Mol. Cell. 16:1003-1015.
-
(2004)
Mol. Cell
, vol.16
, pp. 1003-1015
-
-
Strom, L.1
Lindroos, H.B.2
Shirahige, K.3
Sjogren, C.4
-
33
-
-
1942503933
-
Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins
-
Taddei, A., F. Hediger, F.R. Neumann, C. Bauer, and S.M. Gasser. 2004. Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins. EMBO J. 23:1301-1312.
-
(2004)
EMBO J
, vol.23
, pp. 1301-1312
-
-
Taddei, A.1
Hediger, F.2
Neumann, F.R.3
Bauer, C.4
Gasser, S.M.5
-
34
-
-
2442595631
-
Reciprocal association of the budding yeast ATM-related proteins Tel1 and Mec1 with telomeres in vivo
-
Takata, H., Y. Kanoh, N. Gunge, K. Shirahige, and A. Matsuura. 2004. Reciprocal association of the budding yeast ATM-related proteins Tel1 and Mec1 with telomeres in vivo. Mol. Cell. 14:515-522.
-
(2004)
Mol. Cell
, vol.14
, pp. 515-522
-
-
Takata, H.1
Kanoh, Y.2
Gunge, N.3
Shirahige, K.4
Matsuura, A.5
-
35
-
-
10944262393
-
DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain
-
Unal, E., A. Arbel-Eden, U. Sattler, R. Shroff, M. Lichten, J.E. Haber, and D. Koshland. 2004. DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain. Mol. Cell. 16:991-1002.
-
(2004)
Mol. Cell
, vol.16
, pp. 991-1002
-
-
Unal, E.1
Arbel-Eden, A.2
Sattler, U.3
Shroff, R.4
Lichten, M.5
Haber, J.E.6
Koshland, D.7
-
36
-
-
10944233962
-
Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair
-
van Attikum, H., O. Fritsch, B. Hohn, and S.M. Gasser. 2004. Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair. Cell. 119:777-788.
-
(2004)
Cell
, vol.119
, pp. 777-788
-
-
van Attikum, H.1
Fritsch, O.2
Hohn, B.3
Gasser, S.M.4
-
37
-
-
0036671706
-
Recovery from checkpoint-mediated arrest after repair of a double-strand break requires srs2 helicase
-
Vaze, M.B., A. Pellicioli, S.E. Lee, G. Ira, G. Liberi, A. Arbel-Eden, M. Foiani, and J.E. Haber. 2002. Recovery from checkpoint-mediated arrest after repair of a double-strand break requires srs2 helicase. Mol. Cell. 10:373-385.
-
(2002)
Mol. Cell
, vol.10
, pp. 373-385
-
-
Vaze, M.B.1
Pellicioli, A.2
Lee, S.E.3
Ira, G.4
Liberi, G.5
Arbel-Eden, A.6
Foiani, M.7
Haber, J.E.8
-
38
-
-
0031813153
-
High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating type locus HMLα
-
Weiss, K., and R.T. Simpson. 1998. High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating type locus HMLα. Mol. Cell. Biol. 18:5392-5403.
-
(1998)
Mol. Cell. Biol
, vol.18
, pp. 5392-5403
-
-
Weiss, K.1
Simpson, R.T.2
-
39
-
-
10944219768
-
Control of sister chromatid recombination by histone H2AX
-
Xie, A., N. Puget, I. Shim, S. Odate, I. Jarzyna, C.H. Bassing, F.W. Alt, and R. Scully. 2004. Control of sister chromatid recombination by histone H2AX. Mol. Cell. 16:1017-1025.
-
(2004)
Mol. Cell
, vol.16
, pp. 1017-1025
-
-
Xie, A.1
Puget, N.2
Shim, I.3
Odate, S.4
Jarzyna, I.5
Bassing, C.H.6
Alt, F.W.7
Scully, R.8
-
40
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou, L., and S.J. Elledge. 2003. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science. 300:1542-1548.
-
(2003)
Science
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
|