The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks

Nature

Volumn 447, Issue 7145, 2007, Pages 730-734

  Kruhlak, Michael ^a   Crouch, Elizabeth E ^b   Orlov, Marika ^b   Montão, Carolina ^b   Gorski, Stanislaw A ^a   Nussenzweig, André ^a   Misteli, Tom ^a   Phair, Robert D ^c   Casellas, Rafael ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c Integrative Bioinformatics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; DNA DIRECTED RNA POLYMERASE; DNA POLYMERASE; DOUBLE STRANDED DNA; ENZYME INHIBITOR; FLUOROURIDINE; GREEN FLUORESCENT PROTEIN; HISTONE H2AX; PROTEIN INHIBITOR; PROTEIN MDM2; RIBOSOME RNA; RNA POLYMERASE;

CHROMOSOME; DNA; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC ANALYSIS; IRRADIANCE; RNA; ULTRAVIOLET RADIATION;

ANIMAL CELL; ARTICLE; CHROMOSOME BREAKAGE; CONTROLLED STUDY; DNA REPAIR; DOWN REGULATION; EMBRYO CELL; ENZYME ACTIVITY; ENZYME SUBSTRATE; FIBROBLAST; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GAMMA IRRADIATION; GENOTOXICITY; INHIBITION KINETICS; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RNA SYNTHESIS; TRANSCRIPTION REGULATION;

EID: 34250022502     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05842     Document Type: Article

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