Folate metabolism in human malaria parasites - 75 years on

Molecular and Biochemical Parasitology

Volumn 188, Issue 1, 2013, Pages 63-77

  Müller, Ingrid B ^a   Hyde, John E ^b  

^a BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Antifolate De novo folate synthesis; Drug resistance; Drug targeting; Folate salvage; Intermittent preventative treatment (IPT)

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; 6 PYRUVOYLTETRAHYDROPTERIN SYNTHASE; 6 PYRUVOYLTETRAHYDROPTERIN SYNTHASE III; AZITHROMYCIN; CHLOROQUINE; DIHYDROFOLATE REDUCTASE; DIHYDROFOLATE SYNTHETASE; DIHYDROPTEROATE SYNTHASE; FOLIC ACID; FOLIC ACID ANTAGONIST; FOLINIC ACID; FOLYLPOLYGLUTAMATE SYNTHASE; GLYCINE CLEAVAGE SYSTEM; GLYCINE HYDROXYMETHYLTRANSFERASE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; HYDROXYMETHYLDIHYDROPTERIN PYROPHOSPHOKINASE; MEFLOQUINE; METHIONINE; PHOSPHOTRANSFERASE; PROGUANIL; PYRIMETHAMINE; PYRIMETHAMINE PLUS SULFADOXINE; SULFONAMIDE; SYNTHETASE; THYMIDYLATE SYNTHASE; TRIMETHOPRIM; UNCLASSIFIED DRUG;

BIOSYNTHESIS; FOLATE METABOLISM; HOST; HUMAN; LIFE CYCLE; MALARIA; MALARIA CONTROL; METABOLISM; METABOLOMICS; MUTATION; PLASMODIUM; PLASMODIUM VIVAX; PRIORITY JOURNAL; PROTEOMICS; REVIEW; SYSTEMS BIOLOGY;

ANTIMALARIALS; BIOLOGICAL TRANSPORT; DRUG RESISTANCE; FOLIC ACID; FOLIC ACID ANTAGONISTS; HUMANS; METABOLIC NETWORKS AND PATHWAYS; PLASMODIUM; PTERINS;

EID: 84876700347     PISSN: 01666851     EISSN: 18729428     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2013.02.008     Document Type: Review

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