Comparative folate metabolism in humans and malaria parasites (part I): Pointers for malaria treatment from cancer chemotherapy

Trends in Parasitology

Volumn 21, Issue 6, 2005, Pages 292-298

  Nzila, Alexis ^a,b,c   Ward, Steve A ^c   Marsh, Kevin ^a,d   Sims, Paul F G ^e   Hyde, John E ^e  

^a KEMRI WELLCOME TRUST RESEARCH PROGRAMME   (Kenya)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^d JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 [5 [[(1,2 DIHYDRO 3 METHYL 1 OXOBENZO[F]QUINAZOLIN 9 YL)METHYL]AMINO] 1 OXO 2 ISOINDOLINYL]GLUTARIC ACID; AMINOPTERIN; ANTINEOPLASTIC AGENT; ATOVAQUONE PLUS PROGUANIL; CHLOROQUINE; CHLORPROGUANIL PLUS DAPSONE; CYCLOGUANIL; DIHYDROFOLATE REDUCTASE; DIHYDROFOLATE REDUCTASE INHIBITOR; EDATREXATE; FANSIDAR; FLUOROOROTIC ACID; FLUOROURACIL; FOLIC ACID ANTAGONIST; FOLIC ACID DERIVATIVE; GLYCINE HYDROXYMETHYLTRANSFERASE; GS 7904L; HYDROLASE; METHOTREXATE; NOLATREXED; PEMETREXED; PIRITREXIM; PLEVITREXED; PROGUANIL; PYRIMETHAMINE; RALTITREXED; SYNTHETASE; THYMIDINE; THYMIDYLATE SYNTHASE; THYMIDYLATE SYNTHASE INHIBITOR; TRANSFERASE; TRIMETREXATE; UNCLASSIFIED DRUG; URIDINE;

AMINO ACID METABOLISM; AMINO ACID SYNTHESIS; ANTIBIOTIC RESISTANCE; CANCER CHEMOTHERAPY; CLINICAL TRIAL; COMPARATIVE STUDY; DEVELOPMENTAL STAGE; DNA REPLICATION; DRUG TARGETING; FOLATE METABOLISM; HUMAN; MALARIA; MAMMAL CELL; NONHUMAN; NUCLEOTIDE METABOLISM; PLASMODIUM; PLASMODIUM FALCIPARUM; PROTEIN FUNCTION; PURINE SYNTHESIS; REVIEW;

ANIMALS; ANTIMALARIALS; DRUG RESISTANCE; FOLIC ACID; FOLIC ACID ANTAGONISTS; HUMANS; MALARIA, FALCIPARUM; MULTIENZYME COMPLEXES; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM;

EID: 19444371029     PISSN: 14714922     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pt.2005.04.002     Document Type: Review

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