Co-expression of the Plasmodium falciparum molecular chaperone, PfHsp70, improves the heterologous production of the antimalarial drug target GTP cyclohydrolase I, PfGCHI

Protein Expression and Purification

Volumn 77, Issue 2, 2011, Pages 159-165

  Stephens, Linda L ^a   Shonhai, Addmore ^a,b   Blatch, Gregory L ^a  

^a RHODES UNIVERSITY   (South Africa)

^b UNIVERSITY OF ZULULAND   (South Africa)

Author keywords

Co expression; GTP cyclohydrolase I; Hsp70; Molecular chaperone; Plasmodium falciparum; Protein folding

Indexed keywords

ANTIMALARIAL AGENT; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; HEAT SHOCK PROTEIN 70; HIS HIS HIS HIS HIS HIS; HIS-HIS-HIS-HIS-HIS-HIS; HISTIDINE; OLIGOPEPTIDE; PROTOZOAL PROTEIN; RECOMBINANT PROTEIN;

AFFINITY CHROMATOGRAPHY; ARTICLE; CHEMISTRY; ESCHERICHIA COLI; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALARIA FALCIPARUM; METABOLISM; MOLECULAR CLONING; MOLECULARLY TARGETED THERAPY; PARASITOLOGY; PLASMODIUM FALCIPARUM; SOLUBILITY; SPECTROFLUOROMETRY;

ANTIMALARIALS; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; ESCHERICHIA COLI; GENE EXPRESSION; GENE EXPRESSION REGULATION; GTP CYCLOHYDROLASE; HISTIDINE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MALARIA, FALCIPARUM; MOLECULAR TARGETED THERAPY; OLIGOPEPTIDES; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; SOLUBILITY; SPECTROMETRY, FLUORESCENCE;

PLASMODIUM FALCIPARUM;

EID: 79952620395     PISSN: 10465928     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pep.2011.01.005     Document Type: Article

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