Drug-resistant malaria

Trends in Parasitology

Volumn 21, Issue 11, 2005, Pages 494-498

  Hyde, John E ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMODIAQUINE; ANTIMALARIAL AGENT; ARTEMISIN DERIVATIVE; ARTESUNATE; ATOVAQUONE; ATOVAQUONE PLUS PROGUANIL; BENFLUMETOL; CHLOROQUINE; CHLORPROGUANIL; CHLORPROGUANIL PLUS DAPSONE; DAPSONE; DOXYCYCLINE; FANSIDAR; FOLIC ACID ANTAGONIST; HALOFANTRINE; MEFLOQUINE; PIPERAQUINE; PROGUANIL; PROTOZOAL PROTEIN; PROTOZOAL PROTEIN CRT; PYRIMETHAMINE; QUININE; QUINOLINE DERIVATIVE; SULFADOXINE; TETRACYCLINE; TRIMETHOPRIM; UNCLASSIFIED DRUG; VERAPAMIL;

ANTIBIOTIC RESISTANCE; CLINICAL TRIAL; CODON; CROSS RESISTANCE; GENE MUTATION; GENE TARGETING; HUMAN; MALARIA CONTROL; MALARIA FALCIPARUM; MOLECULAR DYNAMICS; OPEN READING FRAME; PHENOTYPE; PLASMODIUM FALCIPARUM; REVIEW;

ANIMALS; ANTIMALARIALS; DRUG COMBINATIONS; DRUG RESISTANCE; HUMANS; MALARIA; PLASMODIUM;

ARTESUNATE; CINCHONA PUBESCENS; PLASMODIUM FALCIPARUM;

EID: 26844494887     PISSN: 14714922     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pt.2005.08.020     Document Type: Review

References (48)

1. P. Ambroise-Thomas, and J.F. Rossignol Chemotherapy of resistant falciparum malaria Parasitol. Today 2 1986 79 80
2. C. Wongsrichanalai Epidemiology of drug-resistant malaria Lancet Infect. Dis. 2 2002 209 218
3. J.E. Hyde Mechanisms of resistance of Plasmodium falciparum to antimalarial drugs Microbes Infect. 4 2002 165 174
4. B.S. Crabb Transfection technology and the study of drug resistance in the malaria parasite Plasmodium falciparum Drug Resist. Updat. 5 2002 126 130
5. A. Gregson, and C.V. Plowe Mechanisms of resistance of malaria parasites to antifolates Pharmacol. Rev. 57 2005 117 145
6. J.M.R. Carlton Conservation of a novel vacuolar transporter in Plasmodium species and its central role in chloroquine resistance of P. falciparum Curr. Opin. Microbiol. 4 2001 415 420
7. P.G. Bray Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance Mol. Microbiol. 56 2005 323 333
8. X. Su A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum Science 286 1999 1351 1353
9. D.A. Fidock Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance Mol. Cell 6 2000 861 871
10. J.C. Wootton Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum Nature 418 2002 320 323
11. A. Djimde A molecular marker for chloroquine-resistant falciparum malaria N. Engl. J. Med. 344 2001 257 263
12. V. Durrand Variations in the sequence and expression of the Plasmodium falciparum chloroquine resistance transporter (Pfcrt) and their relationship to chloroquine resistance in vitro Mol. Biochem. Parasitol. 136 2004 273 285
13. D.J. Johnson Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents Mol. Cell 15 2004 867 877
14. C.V. Tran, and M.H. Saier The principal chloroquine resistance protein of Plasmodium falciparum is a member of the drug/metabolite transporter superfamily Microbiology 150 2004 1 3
15. R.E. Martin, and K. Kirk The malaria parasite's chloroquine resistance transporter is a member of the drug/metabolite transporter superfamily Mol. Biol. Evol. 21 2004 1938 1949
16. V. Lakshmanan A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance EMBO J. 24 2005 2294 2305
17. W.H. Wernsdorfer, and H. Noedl Molecular markers for drug resistance in malaria: use in treatment, diagnosis and epidemiology Curr. Opin. Infect. Dis. 16 2003 553 558
18. M.T. Duraisingh, and A.F. Cowman Contribution of the pfmdr1 gene to antimalarial drug resistance Acta Trop. 94 2005 181 190
19. M.B. Reed Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum Nature 403 2000 906 909
20. R.N. Price Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number Lancet 364 2004 438 447
21. J. Mu Multiple transporters associated with malaria parasite responses to chloroquine and quinine Mol. Microbiol. 49 2003 977 989
22. A. Alloueche Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trial Lancet 363 2004 1843 1848
23. N.J. White, and W. Pongtavornpinyo The de novo selection of drug-resistant malaria parasites Proc. R. Soc. Lond. Ser. B. Biol. Sci. 270 2003 545 554
24. S.R. Meshnick Artemisinin: mechanisms of action, resistance and toxicity Int. J. Parasitol. 32 2002 1655 1660
25. U. Eckstein-Ludwig Artemisinins target the SERCA of Plasmodium falciparum Nature 424 2003 957 961
26. S. Krishna Artemisinins: mechanisms of action and potential for resistance Drug Resist. Updat. 7 2004 233 244
27. A.C. Uhlemann A single amino acid residue can determine the sensitivity of SERCAs to artemisinins Nat. Struct. Mol. Biol. 12 2005 628 629
28. P.L. Olliaro, and W.R.J. Taylor Antimalarial compounds: from bench to bedside J. Exp. Biol. 206 2003 3753 3759
29. T.M.E. Davis Piperaquine - a resurgent antimalarial drug Drugs 65 2005 75 87
30. N.J. White Antimalarial drug resistance J. Clin. Invest. 113 2004 1084 1092
31. I.K. Srivastava Resistance mutations reveal the atovaquone-binding domain of cytochrome b in malaria parasites Mol. Microbiol. 33 1999 704 711
32. S. Looareesuwan Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand Am. J. Trop. Med. Hyg. 54 1996 62 66
33. A.B. Vaidya, and M.W. Mather Atovaquone resistance in malaria parasites Drug Resist. Updat. 3 2000 283 287
34. M. Korsinczky Mutations in Plasmodium falciparum cytochrome b that are associated with atovaquone resistance are located at a putative drug-binding site Antimicrob. Agents Chemother. 44 2000 2100 2108
35. Q.L. Fivelman Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria Malar. J. 1 2002 1
36. O. Wichmann Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of Plasmodium falciparum in Europe J. Infect. Dis. 190 2004 1541 1546
37. O. Wichmann Malarone treatment failure not associated with previously described mutations in the cytochrome b gene Malar. J. 3 2004 14
38. J.G. Kublin Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi J. Infect. Dis. 187 2003 1870 1875
39. X. Wang Decreased prevalence of the Plasmodium falciparum chloroquine resistance transporter 76T marker associated with cessation of chloroquine use against P. falciparum malaria in Hainan, People's Republic of China Am. J. Trop. Med. Hyg. 72 2005 410 414
40. M. Alifrangis Increasing prevalence of wildtypes in the dihydrofolate reductase gene of Plasmodium falciparum in an area with high levels of sulfadoxine/pyrimethamine resistance after introduction of treated bed nets Am. J. Trop. Med. Hyg. 69 2003 238 243
41. N. Sangster Resistance to antiparasitic drugs: the role of molecular diagnosis Int. J. Parasitol. 32 2002 637 653
42. C.V. Plowe Monitoring antimalarial drug resistance: making the most of the tools at hand J. Exp. Biol. 206 2003 3745 3752
43. M. Alifrangis A simple, high-throughput method to detect Plasmodium falciparum single nucleotide polymorphisms in the dihydrofolate reductase, dihydropteroate synthase, and P. falciparum chloroquine resistance transporter genes using polymerase chain reaction and enzyme-linked immunosorbent assay-based technology Am. J. Trop. Med. Hyg. 72 2005 155 162
44. J.F. Cortese Origin and dissemination of Plasmodium falciparum drug-resistance mutations in South America J. Infect. Dis. 186 2002 999 1006
45. C. Roper Antifolate antimalarial resistance in southeast Africa: a population-based analysis Lancet 361 2003 1174 1181
46. S.A. Ralph Metabolic maps and functions of the Plasmodium falciparum apicoplast Nat. Rev. Microbiol. 2 2004 203 216
47. G.A. Biagini Antimalarial chemotherapy: young guns or back to the future? Trends Parasitol. 19 2003 479 487
48. P.A. Winstanley Clinical status and implications of antimalarial drug resistance Microbes Infect. 4 2002 157 164