Quantitative Structure Activity Relationship Study of 2,4,6-Trisubstituted-s-triazine Derivatives as Antimalarial Inhibitors of Plasmodium Falciparum Dihydrofolate Reductase

Chemical Biology and Drug Design

Volumn 77, Issue 1, 2011, Pages 57-62

  Ojha, Himanshu ^a   Gahlot, Pragya ^a   Tiwari, Anjani K ^a   Pathak, Mallika ^a   Kakkar, Rita ^a  

^a UNIVERSITY OF DELHI   (India)

Author keywords

Antifolates; Antimalarials; GFA approach; QSAR; S triazines

Indexed keywords

2,4,6 TRISUBSTITUTED S TRIAZINE; ANTIMALARIAL AGENT; CARBON; DIHYDROFOLATE REDUCTASE; KAPPA CASEIN; NITROGEN; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHI SQUARE DISTRIBUTION; CORRELATION COEFFICIENT; DIPOLE; MALARIA FALCIPARUM; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANTIMALARIALS; COMPUTER SIMULATION; FOLIC ACID ANTAGONISTS; MALARIA, FALCIPARUM; MODELS, MOLECULAR; PLASMODIUM FALCIPARUM; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDROFOLATE DEHYDROGENASE; TRIAZINES;

PLASMODIUM FALCIPARUM;

EID: 78650168624     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2010.01045.x     Document Type: Article

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