Molecular dynamics of the interaction of Plasmodium falciparum and human serine hydroxymethyltransferase with 5-formyl-6-hydrofolic acid analogues: Design of new potential antimalarials

Journal of the Brazilian Chemical Society

Volumn 17, Issue 7, 2006, Pages 1383-1392

  Fraņca, Tanos C C ^a   Wilter, Alan ^b   Ramalho, Teodorico C ^a   Pascutti, Pedro G ^c   Figueroa Villar, José D ^a  

^a MILITARY INSTITUTE OF ENGINEERING   (Brazil)

^b INSTITUTO NACIONAL DE PESQUISAS ESPACIAIS   (Brazil)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Antimalarial chemotherapy; Drug design; Molecular dynamics; Plasmodium falciparum SHMT; Selective enzymatic inhibition

Indexed keywords

EID: 33845443374     PISSN: 01035053     EISSN: 01035053     Source Type: Journal    
DOI: 10.1590/S0103-50532006000700028     Document Type: Article

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