Loss of malarial susceptibility to artemisinin in Thailand

The Lancet

Volumn 379, Issue 9830, 2012, Pages 1928-1930

  Uhlemann, Anne Catrin ^a   Fidock, David A ^a,b  

^a Division of Infectious Diseases   (United States)

^b New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMISININ; ARTESUNATE; ARTESUNATE PLUS MEFLOQUINE; CLINDAMYCIN; DOXYCYCLINE; PYRIMETHAMINE PLUS SULFADOXINE;

BLOOD SMEAR; CLINICAL EFFECTIVENESS; DISEASE PREDISPOSITION; DRUG EFFICACY; MALARIA; MALARIA CONTROL; MORBIDITY; MORTALITY; MOSQUITO; NONHUMAN; NOTE; PARASITE CLEARANCE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; THAILAND;

EID: 84861436315     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(12)60488-7     Document Type: Note

References (12)

1. Noedl H, Se Y, Schaecher K, Smith BL, Socheat D, Fukuda MM. Evidence of artemisinin-resistant malaria in western Cambodia. N Engl J Med 2008; 359: 2619-20.
2. Dondorp AM, Nosten F, Yi P, et al. Artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med 2009; 361: 455-67.
3. Pyae Pho A, Nkhoma S, Stepniewska K, et al. Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study. Lancet 2012; published online April 5. DOI:10.1016/ S0140-6736(12)60484- X.
4. Flegg JA, Guerin PJ, White NJ, Stepniewska K. Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator. Malar J 2011; 10: 339.
5. Stepniewska K, Ashley E, Lee SJ, et al. In vivo parasitological measures of artemisinin susceptibility. J Infect Dis 2010; 201: 570-79.
6. Barnes KI, Little F, Mabuza A, et al. Increased gametocytemia after treatment: an early parasitological indicator of emerging sulfadoxine- pyrimethamine resistance in falciparum malaria. J Infect Dis 2008; 197: 1605-13.
7. Carrara VI, Zwang J, Ashley EA, et al. Changes in the treatment responses to artesunate-mefl oquine on the northwestern border of Thailand during 13 years of continuous deployment. PLoS One 2009; 4: e4551.
8. Cui L, Yan G, Sattabongkot J, et al. Malaria in the Greater Mekong Subregion: heterogeneity and complexity. Acta Trop 2012; 121: 227-39.
9. O'Brien C, Henrich PP, Passi N, Fidock DA. Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum. Curr Opin Infect Dis 2011; 24: 570-77.
10. Chavchich M, Gerena L, Peters J, Chen N, Cheng Q, Kyle DE. Role of pfmdr1 amplifi cation and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum. Antimicrob Agents Chemother 2010; 54: 2455-64.
11. Saralamba S, Pan-Ngum W, Maude RJ, et al. Intrahost modeling of artemisinin resistance in Plasmodium falciparum. Proc Natl Acad Sci USA 2011; 108: 397-402.
12. Witkowski B, Lelievre J, Barragan MJ, et al. Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism. Antimicrob Agents Chemother 2010; 54: 1872-77.