-
2
-
-
67651085695
-
Aspergillus fumigatus metabolism: Clues to mechanisms of in vivo fungal growth and virulence
-
S.D. Willger, N. Grahl, and R.A. Cramer Jr. Aspergillus fumigatus metabolism: clues to mechanisms of in vivo fungal growth and virulence Med Mycol 47 Suppl. 1 2009 S72 S79
-
(2009)
Med Mycol
, vol.47
, Issue.SUPPL. 1
-
-
Willger, S.D.1
Grahl, N.2
Cramer Jr., R.A.3
-
3
-
-
67049156691
-
Streptococcus pneumoniae and Staphylococcus aureus pneumonia induce distinct metabolic responses
-
C.M. Slupsky, A. Cheypesh, and D.V. Chao Streptococcus pneumoniae and Staphylococcus aureus pneumonia induce distinct metabolic responses J Proteome Res 8 2009 3029 3036
-
(2009)
J Proteome Res
, vol.8
, pp. 3029-3036
-
-
Slupsky, C.M.1
Cheypesh, A.2
Chao, D.V.3
-
4
-
-
67849090833
-
Identification of an overabundant cholesterol precursor in hepatitis B virus replicating cells by untargeted lipid metabolite profiling
-
M.A. Rodgers, A. Saghatelian, and P.L. Yang Identification of an overabundant cholesterol precursor in hepatitis B virus replicating cells by untargeted lipid metabolite profiling J Am Chem Soc 131 2009 5030 5031
-
(2009)
J Am Chem Soc
, vol.131
, pp. 5030-5031
-
-
Rodgers, M.A.1
Saghatelian, A.2
Yang, P.L.3
-
5
-
-
61449176136
-
Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli
-
J.P. Henderson, J.R. Crowley, and J.S. Pinkner Quantitative metabolomics reveals an epigenetic blueprint for iron acquisition in uropathogenic Escherichia coli PLoS Pathog 5 2009 e1000305
-
(2009)
PLoS Pathog
, vol.5
, pp. 1000305
-
-
Henderson, J.P.1
Crowley, J.R.2
Pinkner, J.S.3
-
6
-
-
11144257813
-
Discrimination of pathogenic clinical isolates and laboratory strains of Bacillus cereus by NMR-based metabolomic profiling
-
J.G. Bundy, T.L. Willey, R.S. Castell, D.J. Ellar, and K.M. Brindle Discrimination of pathogenic clinical isolates and laboratory strains of Bacillus cereus by NMR-based metabolomic profiling FEMS Microbiol Lett 242 2005 127 136
-
(2005)
FEMS Microbiol Lett
, vol.242
, pp. 127-136
-
-
Bundy, J.G.1
Willey, T.L.2
Castell, R.S.3
Ellar, D.J.4
Brindle, K.M.5
-
7
-
-
63249088844
-
Co-inhibition of Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase reveals perturbation-specific compensatory mechanisms by transcriptome, proteome, and metabolome analyses
-
A.C. van Brummelen, K.L. Olszewski, D. Wilinski, M. Llinas, A.I. Louw, and L.M. Birkholtz Co-inhibition of Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase reveals perturbation-specific compensatory mechanisms by transcriptome, proteome, and metabolome analyses J Biol Chem 284 2009 4635 4646
-
(2009)
J Biol Chem
, vol.284
, pp. 4635-4646
-
-
Van Brummelen, A.C.1
Olszewski, K.L.2
Wilinski, D.3
Llinas, M.4
Louw, A.I.5
Birkholtz, L.M.6
-
8
-
-
63149174170
-
Glycerol: An unexpected major metabolite of energy metabolism by the human malaria parasite
-
L.Y. Lian, M. Al-Helal, and A.M. Roslaini Glycerol: an unexpected major metabolite of energy metabolism by the human malaria parasite Malar J 8 2009 38
-
(2009)
Malar J
, vol.8
, pp. 38
-
-
Lian, L.Y.1
Al-Helal, M.2
Roslaini, A.M.3
-
9
-
-
33749483184
-
Glycolysis in Plasmodium falciparum results in modulation of host enzyme activities
-
M. Mehta, H.M. Sonawat, and S. Sharma Glycolysis in Plasmodium falciparum results in modulation of host enzyme activities J Vector Borne Dis 43 2006 95 103
-
(2006)
J Vector Borne Dis
, vol.43
, pp. 95-103
-
-
Mehta, M.1
Sonawat, H.M.2
Sharma, S.3
-
10
-
-
60649112444
-
Host-parasite interactions revealed by Plasmodium falciparum metabolomics
-
K.L. Olszewski, J.M. Morrisey, and D. Wilinski Host-parasite interactions revealed by Plasmodium falciparum metabolomics Cell Host Microbe 5 2009 191 199
-
(2009)
Cell Host Microbe
, vol.5
, pp. 191-199
-
-
Olszewski, K.L.1
Morrisey, J.M.2
Wilinski, D.3
-
11
-
-
64949105863
-
Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by (1)H NMR spectroscopy
-
R. Teng, P.R. Junankar, W.A. Bubb, C. Rae, P. Mercier, and K. Kirk Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by (1)H NMR spectroscopy NMR Biomed 22 2009 292 302
-
(2009)
NMR Biomed
, vol.22
, pp. 292-302
-
-
Teng, R.1
Junankar, P.R.2
Bubb, W.A.3
Rae, C.4
Mercier, P.5
Kirk, K.6
-
12
-
-
77951124857
-
Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression
-
A. Basant, M. Rege, S. Sharma, and H.M. Sonawat Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression Malar J 9 2010 110
-
(2010)
Malar J
, vol.9
, pp. 110
-
-
Basant, A.1
Rege, M.2
Sharma, S.3
Sonawat, H.M.4
-
13
-
-
76249110141
-
Eating at the table of another: Metabolomics of host-parasite interactions
-
B.F. Kafsack, and M. Llinas Eating at the table of another: metabolomics of host-parasite interactions Cell Host Microbe 7 2010 90 99
-
(2010)
Cell Host Microbe
, vol.7
, pp. 90-99
-
-
Kafsack, B.F.1
Llinas, M.2
-
14
-
-
70349207216
-
The impact of malaria parasitism: From corpuscles to communities
-
T.E. Wellems, K. Hayton, and R.M. Fairhurst The impact of malaria parasitism: from corpuscles to communities J Clin Invest 119 2009 2496 2505
-
(2009)
J Clin Invest
, vol.119
, pp. 2496-2505
-
-
Wellems, T.E.1
Hayton, K.2
Fairhurst, R.M.3
-
15
-
-
0037015614
-
Genome sequence of the human malaria parasite Plasmodium falciparum
-
M.J. Gardner, N. Hall, and E. Fung Genome sequence of the human malaria parasite Plasmodium falciparum Nature 419 2002 498 511
-
(2002)
Nature
, vol.419
, pp. 498-511
-
-
Gardner, M.J.1
Hall, N.2
Fung, E.3
-
16
-
-
0037015602
-
A proteomic view of the Plasmodium falciparum life cycle
-
L. Florens, M.P. Washburn, and J.D. Raine A proteomic view of the Plasmodium falciparum life cycle Nature 419 2002 520 526
-
(2002)
Nature
, vol.419
, pp. 520-526
-
-
Florens, L.1
Washburn, M.P.2
Raine, J.D.3
-
17
-
-
4243071596
-
The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum
-
Z. Bozdech, M. Llinas, B.L. Pulliam, E.D. Wong, J. Zhu, and J.L. DeRisi The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum PLoS Biol 1 2003 E5
-
(2003)
PLoS Biol
, vol.1
, pp. 5
-
-
Bozdech, Z.1
Llinas, M.2
Pulliam, B.L.3
Wong, E.D.4
Zhu, J.5
Derisi, J.L.6
-
18
-
-
53549090700
-
MalVac: Database of malarial vaccine candidates
-
R. Chaudhuri, S. Ahmed, F.A. Ansari, H.V. Singh, and S. Ramachandran MalVac: database of malarial vaccine candidates Malar J 7 2008 184
-
(2008)
Malar J
, vol.7
, pp. 184
-
-
Chaudhuri, R.1
Ahmed, S.2
Ansari, F.A.3
Singh, H.V.4
Ramachandran, S.5
-
19
-
-
54949145799
-
VarDB: A pathogen-specific sequence database of protein families involved in antigenic variation
-
C.N. Hayes, D. Diez, and N. Joannin varDB: a pathogen-specific sequence database of protein families involved in antigenic variation Bioinformatics 24 2008 2564 2565
-
(2008)
Bioinformatics
, vol.24
, pp. 2564-2565
-
-
Hayes, C.N.1
Diez, D.2
Joannin, N.3
-
21
-
-
68449083308
-
Assessing the impact of transcriptomics, proteomics and metabolomics on fungal phytopathology
-
K.C. Tan, S.V. Ipcho, R.D. Trengove, R.P. Oliver, and P.S. Solomon Assessing the impact of transcriptomics, proteomics and metabolomics on fungal phytopathology Mol Plant Pathol 10 2009 703 715
-
(2009)
Mol Plant Pathol
, vol.10
, pp. 703-715
-
-
Tan, K.C.1
Ipcho, S.V.2
Trengove, R.D.3
Oliver, R.P.4
Solomon, P.S.5
-
22
-
-
56849088375
-
Advances in separation science applied to metabonomics
-
L. Xiayan, and C. Legido-Quigley Advances in separation science applied to metabonomics Electrophoresis 29 2008 3724 3736
-
(2008)
Electrophoresis
, vol.29
, pp. 3724-3736
-
-
Xiayan, L.1
Legido-Quigley, C.2
-
24
-
-
33845631601
-
Microbial metabolomics: Past, present and future methodologies
-
M.R. Mashego, K. Rumbold, M. De Mey, E. Vandamme, W. Soetaert, and J.J. Heijnen Microbial metabolomics: past, present and future methodologies Biotechnol Lett 29 2007 1 16
-
(2007)
Biotechnol Lett
, vol.29
, pp. 1-16
-
-
Mashego, M.R.1
Rumbold, K.2
De Mey, M.3
Vandamme, E.4
Soetaert, W.5
Heijnen, J.J.6
-
25
-
-
45849153463
-
Separation and mass spectrometry in microbial metabolomics
-
D.E. Garcia, E.E. Baidoo, and P.I. Benke Separation and mass spectrometry in microbial metabolomics Curr Opin Microbiol 11 2008 233 239
-
(2008)
Curr Opin Microbiol
, vol.11
, pp. 233-239
-
-
Garcia, D.E.1
Baidoo, E.E.2
Benke, P.I.3
-
26
-
-
66149186970
-
Organic solvent extraction and metabonomic profiling of the metabolites in erythrocytes
-
Y. Zhang, A.J. Wang, and G. Huang Organic solvent extraction and metabonomic profiling of the metabolites in erythrocytes J Chromatogr B Analyt Technol Biomed Life Sci 877 2009 1751 1757
-
(2009)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.877
, pp. 1751-1757
-
-
Zhang, Y.1
Wang, A.J.2
Huang, G.3
-
27
-
-
77950629593
-
Fast sampling for quantitative microbial metabolomics
-
W.M. van Gulik Fast sampling for quantitative microbial metabolomics Curr Opin Biotechnol 21 2010 27 34
-
(2010)
Curr Opin Biotechnol
, vol.21
, pp. 27-34
-
-
Van Gulik, W.M.1
-
28
-
-
78049351897
-
Towards an unbiased metabolic profiling of protozoan parasites: Optimisation of a Leishmania sampling protocol for HILIC-orbitrap analysis
-
R. T'Kindt, A. Jankevics, and R.A. Scheltema Towards an unbiased metabolic profiling of protozoan parasites: optimisation of a Leishmania sampling protocol for HILIC-orbitrap analysis Anal Bioanal Chem 2010
-
(2010)
Anal Bioanal Chem
-
-
T'Kindt, R.1
Jankevics, A.2
Scheltema, R.A.3
-
29
-
-
33847377098
-
From exogenous to endogenous: The inevitable imprint of mass spectrometry in metabolomics
-
E.J. Want, A. Nordstrom, H. Morita, and G. Siuzdak From exogenous to endogenous: the inevitable imprint of mass spectrometry in metabolomics J Proteome Res 6 2007 459 468
-
(2007)
J Proteome Res
, vol.6
, pp. 459-468
-
-
Want, E.J.1
Nordstrom, A.2
Morita, H.3
Siuzdak, G.4
-
30
-
-
28444461025
-
Metabolic fingerprinting of rat urine by LC/MS. Part 1. Analysis by hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry
-
H. Idborg, L. Zamani, P.O. Edlund, I. Schuppe-Koistinen, and S.P. Jacobsson Metabolic fingerprinting of rat urine by LC/MS. Part 1. Analysis by hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry J Chromatogr B Analyt Technol Biomed Life Sci 828 2005 9 13
-
(2005)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.828
, pp. 9-13
-
-
Idborg, H.1
Zamani, L.2
Edlund, P.O.3
Schuppe-Koistinen, I.4
Jacobsson, S.P.5
-
31
-
-
33646743247
-
Nonlinear data alignment for UPLC-MS and HPLC-MS based metabolomics: Quantitative analysis of endogenous and exogenous metabolites in human serum
-
A. Nordstrom, G. O'Maille, C. Qin, and G. Siuzdak Nonlinear data alignment for UPLC-MS and HPLC-MS based metabolomics: quantitative analysis of endogenous and exogenous metabolites in human serum Anal Chem 78 2006 3289 3295
-
(2006)
Anal Chem
, vol.78
, pp. 3289-3295
-
-
Nordstrom, A.1
O'Maille, G.2
Qin, C.3
Siuzdak, G.4
-
32
-
-
73449090797
-
Growing trend of CE at the omics level: The frontier of systems biology
-
E. Oh, M.N. Hasan, and M. Jamshed Growing trend of CE at the omics level: the frontier of systems biology Electrophoresis 31 2010 74 92
-
(2010)
Electrophoresis
, vol.31
, pp. 74-92
-
-
Oh, E.1
Hasan, M.N.2
Jamshed, M.3
-
33
-
-
33846109344
-
Comparing and combining NMR spectroscopy and mass spectrometry in metabolomics
-
Z. Pan, and D. Raftery Comparing and combining NMR spectroscopy and mass spectrometry in metabolomics Anal Bioanal Chem 387 2007 525 527
-
(2007)
Anal Bioanal Chem
, vol.387
, pp. 525-527
-
-
Pan, Z.1
Raftery, D.2
-
34
-
-
75649113424
-
Computational approaches to metabolomics
-
D.S. Wishart Computational approaches to metabolomics Methods Mol Biol 593 2010 283 313
-
(2010)
Methods Mol Biol
, vol.593
, pp. 283-313
-
-
Wishart, D.S.1
-
35
-
-
30744443014
-
Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: Application in metabonomic toxicology studies
-
D.J. Crockford, E. Holmes, and J.C. Lindon Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies Anal Chem 78 2006 363 371
-
(2006)
Anal Chem
, vol.78
, pp. 363-371
-
-
Crockford, D.J.1
Holmes, E.2
Lindon, J.C.3
-
36
-
-
33847006590
-
Recent applications of NMR spectroscopy in plant metabolomics
-
J.L. Ward, J.M. Baker, and M.H. Beale Recent applications of NMR spectroscopy in plant metabolomics FEBS J 274 2007 1126 1131
-
(2007)
FEBS J
, vol.274
, pp. 1126-1131
-
-
Ward, J.L.1
Baker, J.M.2
Beale, M.H.3
-
37
-
-
0032850450
-
Heteronuclear NMR studies of metabolites produced by Cryptococcus neoformans in culture media: Identification of possible virulence factors
-
W.A. Bubb, L.C. Wright, M. Cagney, R.T. Santangelo, T.C. Sorrell, and P.W. Kuchel Heteronuclear NMR studies of metabolites produced by Cryptococcus neoformans in culture media: identification of possible virulence factors Magn Reson Med 42 1999 442 453
-
(1999)
Magn Reson Med
, vol.42
, pp. 442-453
-
-
Bubb, W.A.1
Wright, L.C.2
Cagney, M.3
Santangelo, R.T.4
Sorrell, T.C.5
Kuchel, P.W.6
-
40
-
-
0032124738
-
Proton nuclear magnetic resonance analysis of metabolic end products of the Bolivia strain of Trypanosoma cruzi and three of its clones
-
P. Penin, M. Sanchez-Moreno, and J.A. de Diego Proton nuclear magnetic resonance analysis of metabolic end products of the Bolivia strain of Trypanosoma cruzi and three of its clones Comp Biochem Physiol A Mol Integr Physiol 120 1998 571 574
-
(1998)
Comp Biochem Physiol A Mol Integr Physiol
, vol.120
, pp. 571-574
-
-
Penin, P.1
Sanchez-Moreno, M.2
De Diego, J.A.3
-
41
-
-
27544438209
-
Malaria parasite-infected erythrocytes inhibit glucose utilization in uninfected red cells
-
M. Mehta, H.M. Sonawat, and S. Sharma Malaria parasite-infected erythrocytes inhibit glucose utilization in uninfected red cells FEBS Lett 579 2005 6151 6158
-
(2005)
FEBS Lett
, vol.579
, pp. 6151-6158
-
-
Mehta, M.1
Sonawat, H.M.2
Sharma, S.3
-
43
-
-
0034809599
-
(31)P NMR of apicomplexans and the effects of risedronate on Cryptosporidium parvum growth
-
B. Moreno, B.N. Bailey, and S. Luo (31)P NMR of apicomplexans and the effects of risedronate on Cryptosporidium parvum growth Biochem Biophys Res Commun 284 2001 632 637
-
(2001)
Biochem Biophys Res Commun
, vol.284
, pp. 632-637
-
-
Moreno, B.1
Bailey, B.N.2
Luo, S.3
-
45
-
-
34347405493
-
Data processing for mass spectrometry-based metabolomics
-
M. Katajamaa, and M. Oresic Data processing for mass spectrometry-based metabolomics J Chromatogr A 1158 2007 318 328
-
(2007)
J Chromatogr A
, vol.1158
, pp. 318-328
-
-
Katajamaa, M.1
Oresic, M.2
-
46
-
-
41749113801
-
Biochemical individuality reflected in chromatographic, electrophoretic and mass-spectrometric profiles
-
M.V. Novotny, H.A. Soini, and Y. Mechref Biochemical individuality reflected in chromatographic, electrophoretic and mass-spectrometric profiles J Chromatogr B Analyt Technol Biomed Life Sci 866 2008 26 47
-
(2008)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.866
, pp. 26-47
-
-
Novotny, M.V.1
Soini, H.A.2
Mechref, Y.3
-
47
-
-
41149120242
-
Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models
-
S. Wiklund, E. Johansson, and L. Sjostrom Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models Anal Chem 80 2008 115 122
-
(2008)
Anal Chem
, vol.80
, pp. 115-122
-
-
Wiklund, S.1
Johansson, E.2
Sjostrom, L.3
-
49
-
-
58149119607
-
Caveat emptor: Limitations of the automated reconstruction of metabolic pathways in Plasmodium
-
H. Ginsburg Caveat emptor: limitations of the automated reconstruction of metabolic pathways in Plasmodium Trends Parasitol 25 2009 37 43
-
(2009)
Trends Parasitol
, vol.25
, pp. 37-43
-
-
Ginsburg, H.1
-
50
-
-
0033982936
-
KEGG: Kyoto encyclopedia of genes and genomes
-
M. Kanehisa, and S. Goto KEGG: kyoto encyclopedia of genes and genomes Nucleic Acids Res 28 2000 27 30
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 27-30
-
-
Kanehisa, M.1
Goto, S.2
-
51
-
-
43749099007
-
Assessing the polyamine metabolism of Plasmodium falciparum as chemotherapeutic target
-
I.B. Muller, R. Das Gupta, K. Luersen, C. Wrenger, and R.D. Walter Assessing the polyamine metabolism of Plasmodium falciparum as chemotherapeutic target Mol Biochem Parasitol 160 2008 1 7
-
(2008)
Mol Biochem Parasitol
, vol.160
, pp. 1-7
-
-
Muller, I.B.1
Das Gupta, R.2
Luersen, K.3
Wrenger, C.4
Walter, R.D.5
-
52
-
-
0035017334
-
Targeting polyamines of parasitic protozoa in chemotherapy
-
S. Muller, G.H. Coombs, and R.D. Walter Targeting polyamines of parasitic protozoa in chemotherapy Trends Parasitol 17 2001 242 249
-
(2001)
Trends Parasitol
, vol.17
, pp. 242-249
-
-
Muller, S.1
Coombs, G.H.2
Walter, R.D.3
-
53
-
-
47249122499
-
Polyamines: Essential factors for growth and survival
-
T. Kusano, T. Berberich, C. Tateda, and Y. Takahashi Polyamines: essential factors for growth and survival Planta 228 2008 367 381
-
(2008)
Planta
, vol.228
, pp. 367-381
-
-
Kusano, T.1
Berberich, T.2
Tateda, C.3
Takahashi, Y.4
-
54
-
-
77952953620
-
Functional consequences of perturbing polyamine metabolism in the malaria parasite, Plasmodium falciparum
-
K. Clark, J. Niemand, and S. Reeksting Functional consequences of perturbing polyamine metabolism in the malaria parasite, Plasmodium falciparum Amino Acids 38 2010 633 644
-
(2010)
Amino Acids
, vol.38
, pp. 633-644
-
-
Clark, K.1
Niemand, J.2
Reeksting, S.3
-
55
-
-
0039765384
-
In the human malaria parasite Plasmodium falciparum, polyamines are synthesized by a bifunctional ornithine decarboxylase, S-adenosylmethionine decarboxylase
-
S. Muller, A. Da'dara, and K. Luersen In the human malaria parasite Plasmodium falciparum, polyamines are synthesized by a bifunctional ornithine decarboxylase, S-adenosylmethionine decarboxylase J Biol Chem 275 2000 8097 8102
-
(2000)
J Biol Chem
, vol.275
, pp. 8097-8102
-
-
Muller, S.1
Da'Dara, A.2
Luersen, K.3
-
56
-
-
77950684712
-
Plasmodium falciparum spermidine synthase inhibition results in unique perturbation-specific effects observed on transcript, protein and metabolite levels
-
J.V. Becker, L. Mtwisha, and B.G. Crampton Plasmodium falciparum spermidine synthase inhibition results in unique perturbation-specific effects observed on transcript, protein and metabolite levels BMC Genomics 11 2010 235
-
(2010)
BMC Genomics
, vol.11
, pp. 235
-
-
Becker, J.V.1
Mtwisha, L.2
Crampton, B.G.3
-
57
-
-
0026580108
-
Energy dependence of chloroquine accumulation and chloroquine efflux in Plasmodium falciparum
-
D.J. Krogstad, I.Y. Gluzman, B.L. Herwaldt, P.H. Schlesinger, and T.E. Wellems Energy dependence of chloroquine accumulation and chloroquine efflux in Plasmodium falciparum Biochem Pharmacol 43 1992 57 62
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 57-62
-
-
Krogstad, D.J.1
Gluzman, I.Y.2
Herwaldt, B.L.3
Schlesinger, P.H.4
Wellems, T.E.5
-
58
-
-
0030248458
-
Amodiaquine accumulation in Plasmodium falciparum as a possible explanation for its superior antimalarial activity over chloroquine
-
S.R. Hawley, P.G. Bray, B.K. Park, and S.A. Ward Amodiaquine accumulation in Plasmodium falciparum as a possible explanation for its superior antimalarial activity over chloroquine Mol Biochem Parasitol 80 1996 15 25
-
(1996)
Mol Biochem Parasitol
, vol.80
, pp. 15-25
-
-
Hawley, S.R.1
Bray, P.G.2
Park, B.K.3
Ward, S.A.4
-
59
-
-
79955660777
-
Branched tricarboxylic acid metabolism in Plasmodium falciparum
-
K.L. Olszewski, M.W. Mather, and J.M. Morrisey Branched tricarboxylic acid metabolism in Plasmodium falciparum Nature 466 2010 774 778
-
(2010)
Nature
, vol.466
, pp. 774-778
-
-
Olszewski, K.L.1
Mather, M.W.2
Morrisey, J.M.3
-
61
-
-
77957323256
-
Exploring metabolomic approaches to analyse phospholipid biosynthetic pathways in Plasmodium
-
S. Besteiro, S. Vo Duy, C. Perigaud, I. Lefebvre-Tournier, and H.J. Vial Exploring metabolomic approaches to analyse phospholipid biosynthetic pathways in Plasmodium Parasitology 2010 1 14
-
(2010)
Parasitology
, pp. 1-14
-
-
Besteiro, S.1
Vo Duy, S.2
Perigaud, C.3
Lefebvre-Tournier, I.4
Vial, H.J.5
-
62
-
-
33846965950
-
Scavenging of the cofactor lipoate is essential for the survival of the malaria parasite Plasmodium falciparum
-
M. Allary, J.Z. Lu, L. Zhu, and S.T. Prigge Scavenging of the cofactor lipoate is essential for the survival of the malaria parasite Plasmodium falciparum Mol Microbiol 63 2007 1331 1344
-
(2007)
Mol Microbiol
, vol.63
, pp. 1331-1344
-
-
Allary, M.1
Lu, J.Z.2
Zhu, L.3
Prigge, S.T.4
-
63
-
-
34249912631
-
Fatty acids isolated from Toxoplasma gondii reduce glycosylphosphatidylinositol-induced tumor necrosis factor alpha production through inhibition of the NF-kappaB signaling pathway
-
F. Debierre-Grockiego, K. Rabi, J. Schmidt, H. Geyer, R. Geyer, and R.T. Schwarz Fatty acids isolated from Toxoplasma gondii reduce glycosylphosphatidylinositol-induced tumor necrosis factor alpha production through inhibition of the NF-kappaB signaling pathway Infect Immun 75 2007 2886 2893
-
(2007)
Infect Immun
, vol.75
, pp. 2886-2893
-
-
Debierre-Grockiego, F.1
Rabi, K.2
Schmidt, J.3
Geyer, H.4
Geyer, R.5
Schwarz, R.T.6
-
64
-
-
0141957307
-
Intraerythrocytic Plasmodium falciparum incorporates extraneous fatty acids to its lipids without any structural modification
-
G. Krishnegowda, and D.C. Gowda Intraerythrocytic Plasmodium falciparum incorporates extraneous fatty acids to its lipids without any structural modification Mol Biochem Parasitol 132 2003 55 58
-
(2003)
Mol Biochem Parasitol
, vol.132
, pp. 55-58
-
-
Krishnegowda, G.1
Gowda, D.C.2
-
65
-
-
33750212742
-
Intraerythrocytic Plasmodium falciparum utilize a broad range of serum-derived fatty acids with limited modification for their growth
-
F. Mi-Ichi, K. Kita, and T. Mitamura Intraerythrocytic Plasmodium falciparum utilize a broad range of serum-derived fatty acids with limited modification for their growth Parasitology 133 2006 399 410
-
(2006)
Parasitology
, vol.133
, pp. 399-410
-
-
Mi-Ichi, F.1
Kita, K.2
Mitamura, T.3
-
66
-
-
0026027304
-
Lipid traffic between high density lipoproteins and Plasmodium falciparum-infected red blood cells
-
P. Grellier, D. Rigomier, V. Clavey, J.C. Fruchart, and J. Schrevel Lipid traffic between high density lipoproteins and Plasmodium falciparum-infected red blood cells J Cell Biol 112 1991 267 277
-
(1991)
J Cell Biol
, vol.112
, pp. 267-277
-
-
Grellier, P.1
Rigomier, D.2
Clavey, V.3
Fruchart, J.C.4
Schrevel, J.5
-
67
-
-
64349090650
-
Targeting the fatty acid biosynthesis enzyme, beta-ketoacyl-acyl carrier protein synthase III (PfKASIII), in the identification of novel antimalarial agents
-
P.J. Lee, J.B. Bhonsle, and H.W. Gaona Targeting the fatty acid biosynthesis enzyme, beta-ketoacyl-acyl carrier protein synthase III (PfKASIII), in the identification of novel antimalarial agents J Med Chem 52 2009 952 963
-
(2009)
J Med Chem
, vol.52
, pp. 952-963
-
-
Lee, P.J.1
Bhonsle, J.B.2
Gaona, H.W.3
-
68
-
-
57049187017
-
The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites
-
M. Yu, T.R. Kumar, and L.J. Nkrumah The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites Cell Host Microbe 4 2008 567 578
-
(2008)
Cell Host Microbe
, vol.4
, pp. 567-578
-
-
Yu, M.1
Kumar, T.R.2
Nkrumah, L.J.3
-
69
-
-
59849125892
-
Type II fatty acid synthesis is essential only for malaria parasite late liver stage development
-
A.M. Vaughan, M.T. O'Neill, and A.S. Tarun Type II fatty acid synthesis is essential only for malaria parasite late liver stage development Cell Microbiol 11 2009 506 520
-
(2009)
Cell Microbiol
, vol.11
, pp. 506-520
-
-
Vaughan, A.M.1
O'Neill, M.T.2
Tarun, A.S.3
-
70
-
-
0035126479
-
Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum
-
N. Surolia, and A. Surolia Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum Nat Med 7 2001 167 173
-
(2001)
Nat Med
, vol.7
, pp. 167-173
-
-
Surolia, N.1
Surolia, A.2
-
71
-
-
37249026903
-
Distinct physiological states of Plasmodium falciparum in malaria-infected patients
-
J.P. Daily, D. Scanfeld, and N. Pochet Distinct physiological states of Plasmodium falciparum in malaria-infected patients Nature 450 2007 1091 1095
-
(2007)
Nature
, vol.450
, pp. 1091-1095
-
-
Daily, J.P.1
Scanfeld, D.2
Pochet, N.3
-
72
-
-
66149141833
-
Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture
-
J.E. Lemieux, N. Gomez-Escobar, and A. Feller Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture Proc Natl Acad Sci USA 106 2009 7559 7564
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 7559-7564
-
-
Lemieux, J.E.1
Gomez-Escobar, N.2
Feller, A.3
-
73
-
-
0037438687
-
Malaria-parasitized erythrocytes and hemozoin nonenzymatically generate large amounts of hydroxy fatty acids that inhibit monocyte functions
-
E. Schwarzer, H. Kuhn, E. Valente, and P. Arese Malaria-parasitized erythrocytes and hemozoin nonenzymatically generate large amounts of hydroxy fatty acids that inhibit monocyte functions Blood 101 2003 722 728
-
(2003)
Blood
, vol.101
, pp. 722-728
-
-
Schwarzer, E.1
Kuhn, H.2
Valente, E.3
Arese, P.4
-
74
-
-
77349101831
-
The evolution, metabolism and functions of the apicoplast
-
L. Lim, and G.I. McFadden The evolution, metabolism and functions of the apicoplast Philos Trans R Soc Lond B Biol Sci 365 2010 749 763
-
(2010)
Philos Trans R Soc Lond B Biol Sci
, vol.365
, pp. 749-763
-
-
Lim, L.1
McFadden, G.I.2
-
75
-
-
10644295471
-
The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum
-
M.B. Cassera, F.C. Gozzo, and F.L. D'Alexandri The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum J Biol Chem 279 2004 51749 51759
-
(2004)
J Biol Chem
, vol.279
, pp. 51749-51759
-
-
Cassera, M.B.1
Gozzo, F.C.2
D'Alexandri, F.L.3
-
76
-
-
0033179512
-
Active isoprenoid pathway in the intra-erythrocytic stages of Plasmodium falciparum: Presence of dolichols of 11 and 12 isoprene units
-
A.S. Couto, E.A. Kimura, V.J. Peres, M.L. Uhrig, and A.M. Katzin Active isoprenoid pathway in the intra-erythrocytic stages of Plasmodium falciparum: presence of dolichols of 11 and 12 isoprene units Biochem J 341 Pt 3 1999 629 637
-
(1999)
Biochem J
, vol.341
, Issue.PART 3
, pp. 629-637
-
-
Couto, A.S.1
Kimura, E.A.2
Peres, V.J.3
Uhrig, M.L.4
Katzin, A.M.5
-
77
-
-
28044458534
-
Identification, molecular cloning and functional characterization of an octaprenyl pyrophosphate synthase in intra-erythrocytic stages of Plasmodium falciparum
-
R. Tonhosolo, F.L. D'Alexandri, and F.A. Genta Identification, molecular cloning and functional characterization of an octaprenyl pyrophosphate synthase in intra-erythrocytic stages of Plasmodium falciparum Biochem J 392 2005 117 126
-
(2005)
Biochem J
, vol.392
, pp. 117-126
-
-
Tonhosolo, R.1
D'Alexandri, F.L.2
Genta, F.A.3
-
78
-
-
65649083375
-
Carotenoid biosynthesis in intraerythrocytic stages of Plasmodium falciparum
-
R. Tonhosolo, F.L. D'Alexandri, and V.V. de Rosso Carotenoid biosynthesis in intraerythrocytic stages of Plasmodium falciparum J Biol Chem 284 2009 9974 9985
-
(2009)
J Biol Chem
, vol.284
, pp. 9974-9985
-
-
Tonhosolo, R.1
D'Alexandri, F.L.2
De Rosso, V.V.3
-
79
-
-
23144448511
-
Discovery of the principal specific transcription factors of Apicomplexa and their implication for the evolution of the AP2-integrase DNA binding domains
-
S. Balaji, M.M. Babu, L.M. Iyer, and L. Aravind Discovery of the principal specific transcription factors of Apicomplexa and their implication for the evolution of the AP2-integrase DNA binding domains Nucleic Acids Res 33 2005 3994 4006
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 3994-4006
-
-
Balaji, S.1
Babu, M.M.2
Iyer, L.M.3
Aravind, L.4
-
80
-
-
76649113436
-
Plant homologs of the Plasmodium falciparum chloroquine-resistance transporter, PfCRT, are required for glutathione homeostasis and stress responses
-
S.C. Maughan, M. Pasternak, and N. Cairns Plant homologs of the Plasmodium falciparum chloroquine-resistance transporter, PfCRT, are required for glutathione homeostasis and stress responses Proc Natl Acad Sci USA 107 2010 2331 2336
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2331-2336
-
-
Maughan, S.C.1
Pasternak, M.2
Cairns, N.3
-
81
-
-
18044387854
-
Metabolomics, genomics, proteomics, and the identification of enzymes and their substrates and products
-
E. Fridman, and E. Pichersky Metabolomics, genomics, proteomics, and the identification of enzymes and their substrates and products Curr Opin Plant Biol 8 2005 242 248
-
(2005)
Curr Opin Plant Biol
, vol.8
, pp. 242-248
-
-
Fridman, E.1
Pichersky, E.2
-
82
-
-
66349083647
-
Graph theoretical approach to study eQTL: A case study of Plasmodium falciparum
-
Y. Huang, S. Wuchty, M.T. Ferdig, and T.M. Przytycka Graph theoretical approach to study eQTL: a case study of Plasmodium falciparum Bioinformatics 25 2009 i15 20
-
(2009)
Bioinformatics
, vol.25
, pp. 15-20
-
-
Huang, Y.1
Wuchty, S.2
Ferdig, M.T.3
Przytycka, T.M.4
-
83
-
-
55549143016
-
Disruption of the Plasmodium falciparum PfPMT gene results in a complete loss of phosphatidylcholine biosynthesis via the serine-decarboxylase- phosphoethanolamine-methyltransferase pathway and severe growth and survival defects
-
W.H. Witola, K. El Bissati, G. Pessi, C. Xie, P.D. Roepe, and C.B. Mamoun Disruption of the Plasmodium falciparum PfPMT gene results in a complete loss of phosphatidylcholine biosynthesis via the serine-decarboxylase- phosphoethanolamine-methyltransferase pathway and severe growth and survival defects J Biol Chem 283 2008 27636 27643
-
(2008)
J Biol Chem
, vol.283
, pp. 27636-27643
-
-
Witola, W.H.1
El Bissati, K.2
Pessi, G.3
Xie, C.4
Roepe, P.D.5
Mamoun, C.B.6
-
84
-
-
0033757963
-
Metabolite profiling for plant functional genomics
-
O. Fiehn, J. Kopka, P. Dormann, T. Altmann, R.N. Trethewey, and L. Willmitzer Metabolite profiling for plant functional genomics Nat Biotechnol 18 2000 1157 1161
-
(2000)
Nat Biotechnol
, vol.18
, pp. 1157-1161
-
-
Fiehn, O.1
Kopka, J.2
Dormann, P.3
Altmann, T.4
Trethewey, R.N.5
Willmitzer, L.6
-
85
-
-
33747169854
-
Metabolomics approach for enzyme discovery
-
N. Saito, M. Robert, and S. Kitamura Metabolomics approach for enzyme discovery J Proteome Res 5 2006 1979 1987
-
(2006)
J Proteome Res
, vol.5
, pp. 1979-1987
-
-
Saito, N.1
Robert, M.2
Kitamura, S.3
-
86
-
-
53949087361
-
Heterologous expression of plasmodial proteins for structural studies and functional annotation
-
L.M. Birkholtz, G. Blatch, and T.L. Coetzer Heterologous expression of plasmodial proteins for structural studies and functional annotation Malar J 7 2008 197
-
(2008)
Malar J
, vol.7
, pp. 197
-
-
Birkholtz, L.M.1
Blatch, G.2
Coetzer, T.L.3
-
88
-
-
33847398001
-
Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum
-
H.J. Painter, J.M. Morrisey, M.W. Mather, and A.B. Vaidya Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum Nature 446 2007 88 91
-
(2007)
Nature
, vol.446
, pp. 88-91
-
-
Painter, H.J.1
Morrisey, J.M.2
Mather, M.W.3
Vaidya, A.B.4
-
89
-
-
75549083436
-
PeroxisomeDB 2.0: An integrative view of the global peroxisomal metabolome
-
A. Schluter, A. Real-Chicharro, T. Gabaldon, F. Sanchez-Jimenez, and A. Pujol PeroxisomeDB 2.0: an integrative view of the global peroxisomal metabolome Nucleic Acids Res 38 2010 D800 D805
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Schluter, A.1
Real-Chicharro, A.2
Gabaldon, T.3
Sanchez-Jimenez, F.4
Pujol, A.5
-
90
-
-
13844256486
-
Functional genomics and insect chemical ecology
-
C. Tittiger Functional genomics and insect chemical ecology J Chem Ecol 30 2004 2335 2358
-
(2004)
J Chem Ecol
, vol.30
, pp. 2335-2358
-
-
Tittiger, C.1
-
91
-
-
0034901477
-
Both mosquito-derived xanthurenic acid and a host blood-derived factor regulate gametogenesis of Plasmodium in the midgut of the mosquito
-
M. Arai, O. Billker, and H.R. Morris Both mosquito-derived xanthurenic acid and a host blood-derived factor regulate gametogenesis of Plasmodium in the midgut of the mosquito Mol Biochem Parasitol 116 2001 17 24
-
(2001)
Mol Biochem Parasitol
, vol.116
, pp. 17-24
-
-
Arai, M.1
Billker, O.2
Morris, H.R.3
-
92
-
-
0025820721
-
Why do some African children develop severe malaria?
-
B. Greenwood, K. Marsh, and R. Snow Why do some African children develop severe malaria? Parasitol Today 7 1991 277 281
-
(1991)
Parasitol Today
, vol.7
, pp. 277-281
-
-
Greenwood, B.1
Marsh, K.2
Snow, R.3
-
94
-
-
34147120638
-
Molecular factors and biochemical pathways induced by febrile temperature in intraerythrocytic Plasmodium falciparum parasites
-
M.S. Oakley, S. Kumar, and V. Anantharaman Molecular factors and biochemical pathways induced by febrile temperature in intraerythrocytic Plasmodium falciparum parasites Infect Immun 75 2007 2012 2025
-
(2007)
Infect Immun
, vol.75
, pp. 2012-2025
-
-
Oakley, M.S.1
Kumar, S.2
Anantharaman, V.3
-
95
-
-
52949093871
-
African genetic diversity: Implications for human demographic history, modern human origins, and complex disease mapping
-
M.C. Campbell, and S.A. Tishkoff African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping Annu Rev Genomics Hum Genet 9 2008 403 433
-
(2008)
Annu Rev Genomics Hum Genet
, vol.9
, pp. 403-433
-
-
Campbell, M.C.1
Tishkoff, S.A.2
-
96
-
-
6444243156
-
Metabolomics: An emerging post-genomic tool for nutrition
-
P.D. Whitfield, A.J. German, and P.J. Noble Metabolomics: an emerging post-genomic tool for nutrition Br J Nutr 92 2004 549 555
-
(2004)
Br J Nutr
, vol.92
, pp. 549-555
-
-
Whitfield, P.D.1
German, A.J.2
Noble, P.J.3
-
97
-
-
27244437784
-
Metabolomics in human nutrition: Opportunities and challenges
-
M.J. Gibney, M. Walsh, L. Brennan, H.M. Roche, B. German, and B. van Ommen Metabolomics in human nutrition: opportunities and challenges Am J Clin Nutr 82 2005 497 503
-
(2005)
Am J Clin Nutr
, vol.82
, pp. 497-503
-
-
Gibney, M.J.1
Walsh, M.2
Brennan, L.3
Roche, H.M.4
German, B.5
Van Ommen, B.6
-
98
-
-
70450263593
-
Genomic and metabolomic advances in the identification of disease and adverse event biomarkers
-
D.L. Mendrick, and L. Schnackenberg Genomic and metabolomic advances in the identification of disease and adverse event biomarkers Biomark Med 3 2009 605 615
-
(2009)
Biomark Med
, vol.3
, pp. 605-615
-
-
Mendrick, D.L.1
Schnackenberg, L.2
-
100
-
-
1642602656
-
Differentiating the pathologies of cerebral malaria by postmortem parasite counts
-
T.E. Taylor, W.J. Fu, and R.A. Carr Differentiating the pathologies of cerebral malaria by postmortem parasite counts Nat Med 10 2004 143 145
-
(2004)
Nat Med
, vol.10
, pp. 143-145
-
-
Taylor, T.E.1
Fu, W.J.2
Carr, R.A.3
-
101
-
-
0036135795
-
Diagnosis of placental malaria
-
F.P. Mockenhaupt, U. Ulmen, C. von Gaertner, G. Bedu-Addo, and U. Bienzle Diagnosis of placental malaria J Clin Microbiol 40 2002 306 308
-
(2002)
J Clin Microbiol
, vol.40
, pp. 306-308
-
-
Mockenhaupt, F.P.1
Ulmen, U.2
Von Gaertner, C.3
Bedu-Addo, G.4
Bienzle, U.5
-
102
-
-
33746065648
-
Understanding mouse models of disease through metabolomics
-
J.L. Griffin Understanding mouse models of disease through metabolomics Curr Opin Chem Biol 10 2006 309 315
-
(2006)
Curr Opin Chem Biol
, vol.10
, pp. 309-315
-
-
Griffin, J.L.1
-
103
-
-
0034602943
-
Cross-species interactions between malaria parasites in humans
-
M.C. Bruce, C.A. Donnelly, and M.P. Alpers Cross-species interactions between malaria parasites in humans Science 287 2000 845 848
-
(2000)
Science
, vol.287
, pp. 845-848
-
-
Bruce, M.C.1
Donnelly, C.A.2
Alpers, M.P.3
-
104
-
-
0038359616
-
Cross-species regulation of Plasmodium parasitemia in semi-immune children from Papua New Guinea
-
M.C. Bruce, and K.P. Day Cross-species regulation of Plasmodium parasitemia in semi-immune children from Papua New Guinea Trends Parasitol 19 2003 271 277
-
(2003)
Trends Parasitol
, vol.19
, pp. 271-277
-
-
Bruce, M.C.1
Day, K.P.2
-
105
-
-
35348845845
-
Metabolic fingerprinting as a diagnostic tool
-
D.I. Ellis, W.B. Dunn, J.L. Griffin, J.W. Allwood, and R. Goodacre Metabolic fingerprinting as a diagnostic tool Pharmacogenomics 8 2007 1243 1266
-
(2007)
Pharmacogenomics
, vol.8
, pp. 1243-1266
-
-
Ellis, D.I.1
Dunn, W.B.2
Griffin, J.L.3
Allwood, J.W.4
Goodacre, R.5
-
106
-
-
67849133745
-
Analytical strategies in lipidomics and applications in disease biomarker discovery
-
C. Hu, R. van der Heijden, M. Wang, J. van der Greef, T. Hankemeier, and G. Xu Analytical strategies in lipidomics and applications in disease biomarker discovery J Chromatogr B Analyt Technol Biomed Life Sci 877 2009 2836 2846
-
(2009)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.877
, pp. 2836-2846
-
-
Hu, C.1
Van Der Heijden, R.2
Wang, M.3
Van Der Greef, J.4
Hankemeier, T.5
Xu, G.6
|