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Volumn 20, Issue 3, 2004, Pages 109-112

Therapeutic potential of folate uptake inhibition in Plasmodium falciparum

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; CHLORCYCLOGUANIL; DAPSONE; DIHYDROFOLATE REDUCTASE INHIBITOR; FANSIDAR; FOLIC ACID ANTAGONIST; METHOTREXATE; PENICILLIN G; PROBENECID; PYRIMETHAMINE; SULFADOXINE; URICOSURIC AGENT;

EID: 1342328135     PISSN: 14714922     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pt.2003.12.005     Document Type: Short Survey
Times cited : (16)

References (31)
  • 1
    • 0035856231 scopus 로고    scopus 로고
    • Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania
    • Mutabingwa T., et al. Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania. Lancet. 358:2001;1218-1223.
    • (2001) Lancet , vol.358 , pp. 1218-1223
    • Mutabingwa, T.1
  • 2
    • 0034065697 scopus 로고    scopus 로고
    • Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: Genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites
    • Nzila A.M., et al. Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites. Antimicrob. Agents Chemother. 44:2000;991-996.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 991-996
    • Nzila, A.M.1
  • 3
    • 0035806761 scopus 로고    scopus 로고
    • Amodiaquine, sulfadoxine/pyrimethamine, and combination therapy for treatment of uncomplicated falciparum malaria in Kampala, Uganda: A randomised trial
    • Staedke S.G., et al. Amodiaquine, sulfadoxine/pyrimethamine, and combination therapy for treatment of uncomplicated falciparum malaria in Kampala, Uganda: a randomised trial. Lancet. 358:2001;368-374.
    • (2001) Lancet , vol.358 , pp. 368-374
    • Staedke, S.G.1
  • 4
    • 0037316971 scopus 로고    scopus 로고
    • Treatment history and treatment dose are important determinants of sulfadoxine-pyrimethamine efficacy in children with uncomplicated malaria in Western Kenya
    • Terlouw D.J., et al. Treatment history and treatment dose are important determinants of sulfadoxine-pyrimethamine efficacy in children with uncomplicated malaria in Western Kenya. J. Infect. Dis. 187:2003;467-476.
    • (2003) J. Infect. Dis. , vol.187 , pp. 467-476
    • Terlouw, D.J.1
  • 5
    • 0035702490 scopus 로고    scopus 로고
    • Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: What next?
    • Sibley C.H., et al. Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next? Trends Parasitol. 17:2001;582-588.
    • (2001) Trends Parasitol. , vol.17 , pp. 582-588
    • Sibley, C.H.1
  • 6
    • 0033027433 scopus 로고    scopus 로고
    • The antimalarial triazine WR99210 and the prodrug PS-15: Folate reversal of in vitro activity against Plasmodium falciparum and a non-antifolate mode of action of the prodrug
    • Kinyanjui S.M., et al. The antimalarial triazine WR99210 and the prodrug PS-15: folate reversal of in vitro activity against Plasmodium falciparum and a non-antifolate mode of action of the prodrug. Am. J. Trop. Med. Hyg. 60:1999;943-947.
    • (1999) Am. J. Trop. Med. Hyg. , vol.60 , pp. 943-947
    • Kinyanjui, S.M.1
  • 7
    • 0029557546 scopus 로고
    • Iron, but not folic acid, combined with effective antimalarial therapy promotes haematological recovery in African children after acute falciparum malaria
    • van Hensbroek M.B., et al. Iron, but not folic acid, combined with effective antimalarial therapy promotes haematological recovery in African children after acute falciparum malaria. Trans. R. Soc. Trop. Med. Hyg. 89:1995;672-676.
    • (1995) Trans. R. Soc. Trop. Med. Hyg. , vol.89 , pp. 672-676
    • Van Hensbroek, M.B.1
  • 8
    • 0021965988 scopus 로고
    • Antagonism of sulfadoxine and pyrimethamine antimalarial activity in vitro by p-aminobenzoic acid, p-aminobenzoylglutamic acid and folic acid
    • Watkins W.M., et al. Antagonism of sulfadoxine and pyrimethamine antimalarial activity in vitro by p-aminobenzoic acid, p-aminobenzoylglutamic acid and folic acid. Mol. Biochem. Parasitol. 14:1985;55-61.
    • (1985) Mol. Biochem. Parasitol. , vol.14 , pp. 55-61
    • Watkins, W.M.1
  • 9
    • 0030868588 scopus 로고    scopus 로고
    • A modified in vitro sulfadoxine susceptibility assay for Plasmodium falciparum suitable for investigating Fansidar resistance
    • Wang P., et al. A modified in vitro sulfadoxine susceptibility assay for Plasmodium falciparum suitable for investigating Fansidar resistance. Parasitology. 115:1997;223-230.
    • (1997) Parasitology , vol.115 , pp. 223-230
    • Wang, P.1
  • 10
    • 0033022037 scopus 로고    scopus 로고
    • Utilization of exogenous folate in the human malaria parasite Plasmodium falciparum and its critical role in antifolate drug synergy
    • Wang P., et al. Utilization of exogenous folate in the human malaria parasite Plasmodium falciparum and its critical role in antifolate drug synergy. Mol. Microbiol. 32:1999;1254-1262.
    • (1999) Mol. Microbiol. , vol.32 , pp. 1254-1262
    • Wang, P.1
  • 11
    • 0033813261 scopus 로고    scopus 로고
    • Co-administration of probenecid, an inhibitor of a cMOAT/MRP-like plasma membrane ATPase, greatly enhanced the efficacy of a new 10-deazaaminopterin against human solid tumors in vivo
    • Sirotnak F.M., et al. Co-administration of probenecid, an inhibitor of a cMOAT/MRP-like plasma membrane ATPase, greatly enhanced the efficacy of a new 10-deazaaminopterin against human solid tumors in vivo. Clin. Cancer Res. 6:2000;3705-3712.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 3705-3712
    • Sirotnak, F.M.1
  • 12
    • 0027351189 scopus 로고
    • Karnofsky memorial lecture. Ode to methotrexate
    • Bertino J.R. Karnofsky memorial lecture. Ode to methotrexate. J. Clin. Oncol. 11:1993;5-14.
    • (1993) J. Clin. Oncol. , vol.11 , pp. 5-14
    • Bertino, J.R.1
  • 13
    • 0035230890 scopus 로고    scopus 로고
    • Molecular and cellular biology of the human reduced folate carrier
    • Matherly L.H. Molecular and cellular biology of the human reduced folate carrier. Prog. Nucleic Acid Res. Mol. Biol. 67:2001;131-162.
    • (2001) Prog. Nucleic Acid Res. Mol. Biol. , vol.67 , pp. 131-162
    • Matherly, L.H.1
  • 14
    • 0032936786 scopus 로고    scopus 로고
    • Recent advances in the understanding of the mechanism of membrane transport of folates and antifolates
    • Sierra E.E., Goldman I.D. Recent advances in the understanding of the mechanism of membrane transport of folates and antifolates. Semin. Oncol. 26:1999;11-23.
    • (1999) Semin. Oncol. , vol.26 , pp. 11-23
    • Sierra, E.E.1    Goldman, I.D.2
  • 15
    • 0032807982 scopus 로고    scopus 로고
    • Carrier-mediated membrane transport of folates in mammalian cells
    • Sirotnak F.M., Tolner B. Carrier-mediated membrane transport of folates in mammalian cells. Annu. Rev. Nutr. 19:1999;91-122.
    • (1999) Annu. Rev. Nutr. , vol.19 , pp. 91-122
    • Sirotnak, F.M.1    Tolner, B.2
  • 16
    • 0029818146 scopus 로고    scopus 로고
    • Folate receptors
    • Antony A.C. Folate receptors. Annu. Rev. Nutr. 16:1996;501-521.
    • (1996) Annu. Rev. Nutr. , vol.16 , pp. 501-521
    • Antony, A.C.1
  • 17
    • 0037130286 scopus 로고    scopus 로고
    • Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase
    • Banerjee D., et al. Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase. Biochim. Biophys. Acta. 1587:2002;164-173.
    • (2002) Biochim. Biophys. Acta , vol.1587 , pp. 164-173
    • Banerjee, D.1
  • 18
    • 0033001234 scopus 로고    scopus 로고
    • Mechanisms of methotrexate resistance in osteosarcoma
    • Guo W., et al. Mechanisms of methotrexate resistance in osteosarcoma. Clin. Cancer Res. 5:1999;621-627.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 621-627
    • Guo, W.1
  • 19
    • 0032605142 scopus 로고    scopus 로고
    • Mechanisms of methotrexate resistance in acute leukemia. Decreased transport and polyglutamylation
    • Gorlick R., et al. Mechanisms of methotrexate resistance in acute leukemia. Decreased transport and polyglutamylation. Adv. Exp. Med. Biol. 457:1999;543-550.
    • (1999) Adv. Exp. Med. Biol. , vol.457 , pp. 543-550
    • Gorlick, R.1
  • 20
    • 0033152212 scopus 로고    scopus 로고
    • Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2
    • Hooijberg J.H., et al. Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2. Cancer Res. 59:1999;2532-2535.
    • (1999) Cancer Res. , vol.59 , pp. 2532-2535
    • Hooijberg, J.H.1
  • 21
    • 0032750225 scopus 로고    scopus 로고
    • The multidrug resistance protein family
    • Borst P., et al. The multidrug resistance protein family. Biochim. Biophys. Acta. 1461:1999;347-357.
    • (1999) Biochim. Biophys. Acta , vol.1461 , pp. 347-357
    • Borst, P.1
  • 22
    • 0034674901 scopus 로고    scopus 로고
    • A family of drug transporters: The multidrug resistance-associated proteins
    • Borst P., et al. A family of drug transporters: the multidrug resistance-associated proteins. J. Natl. Cancer Inst. 92:2000;1295-1302.
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 1295-1302
    • Borst, P.1
  • 23
    • 0034717893 scopus 로고    scopus 로고
    • ABC transporters in lipid transport
    • Borst P., et al. ABC transporters in lipid transport. Biochim. Biophys. Acta. 1486:2000;128-144.
    • (2000) Biochim. Biophys. Acta , vol.1486 , pp. 128-144
    • Borst, P.1
  • 24
    • 0038676970 scopus 로고    scopus 로고
    • Chemosensitization of Plasmodium falciparum by probenecid in vitro
    • Nzila A., et al. Chemosensitization of Plasmodium falciparum by probenecid in vitro. Antimicrob. Agents Chemother. 47:2003;2108-2112.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 2108-2112
    • Nzila, A.1
  • 25
    • 0030813699 scopus 로고    scopus 로고
    • The efficacy of antifolate antimalarial combination in Africa: A predictive model based on pharmacodynamic and pharmacokinetic analyses
    • Watkins W.M., et al. The efficacy of antifolate antimalarial combination in Africa: a predictive model based on pharmacodynamic and pharmacokinetic analyses. Parasitol. Today. 13:1997;459-464.
    • (1997) Parasitol. Today , vol.13 , pp. 459-464
    • Watkins, W.M.1
  • 26
    • 0033938669 scopus 로고    scopus 로고
    • The multispecific organic anion transporter (OAT) family
    • Sekine T., et al. The multispecific organic anion transporter (OAT) family. Pflugers Arch. 440:2000;337-350.
    • (2000) Pflugers Arch. , vol.440 , pp. 337-350
    • Sekine, T.1
  • 27
    • 0036076780 scopus 로고    scopus 로고
    • Characterization of methotrexate transport and its drug interactions with human organic anion transporters
    • Takeda M., et al. Characterization of methotrexate transport and its drug interactions with human organic anion transporters. J. Pharmacol. Exp. Ther. 302:2002;666-671.
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , pp. 666-671
    • Takeda, M.1
  • 28
    • 0032936786 scopus 로고    scopus 로고
    • Recent advances in the understanding of the mechanism of membrane transport of folates and antifolates
    • Sierra E.E., Goldman I.D. Recent advances in the understanding of the mechanism of membrane transport of folates and antifolates. Semin. Oncol. 26:1999;11-23.
    • (1999) Semin. Oncol. , vol.26 , pp. 11-23
    • Sierra, E.E.1    Goldman, I.D.2
  • 29
    • 0030885188 scopus 로고    scopus 로고
    • Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil
    • Fidock D.A., Wellems T.E. Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil. Proc. Natl. Acad. Sci. U. S. A. 94:1997;10931-10936.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 10931-10936
    • Fidock, D.A.1    Wellems, T.E.2
  • 30
    • 0025760770 scopus 로고
    • Pyrimethamine-resistant Plasmodium falciparum lack cross-resistance to methotrexate and 2,4-diamino-5-(substituted benzyl) pyrimidines
    • Walter R., et al. Pyrimethamine-resistant Plasmodium falciparum lack cross-resistance to methotrexate and 2,4-diamino-5-(substituted benzyl) pyrimidines. Parasitol. Res. 77:1991;346-350.
    • (1991) Parasitol. Res. , vol.77 , pp. 346-350
    • Walter, R.1
  • 31
    • 0019807956 scopus 로고
    • Clinical pharmacokinetics of probenecid
    • Cunningham R.F., et al. Clinical pharmacokinetics of probenecid. Clin. Pharmacokinet. 6:1981;135-151.
    • (1981) Clin. Pharmacokinet. , vol.6 , pp. 135-151
    • Cunningham, R.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.