Mutations in the BRCT binding site of BRCA1 result in hyperrecombination

Aging

Volumn 3, Issue 5, 2011, Pages 515-532

  Dever, Seth M ^a,b   Golding, Sarah E ^a   Rosenberg, Elizabeth ^a   Adams, Bret R ^a,b   Idowu, Michael O ^b   Quillin, John M ^a,b   Valerie, Nicholas ^a   Xu, Bo ^c   Povirk, Lawrence F ^a,b   Valerie, Kristoffer ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c HOUSTON METHODIST HOSPITAL   (United States)

Author keywords

Breast cancer; DNA damage; DNA repair; PML bodies; Radiation; Ubiquitination

Indexed keywords

BRCA1 PROTEIN; CARRIER PROTEIN; DNA; NUCLEAR PROTEIN; PML PROTEIN, HUMAN; RAD51 PROTEIN; RBBP8 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; BINDING SITE; BREAST TUMOR; CELL NUCLEUS; CELL STRAIN HEK293; CHEMISTRY; DNA REPAIR; FEMALE; GENE VECTOR; GENETIC RECOMBINATION; GENETICS; HUMAN; METABOLISM; MUTATION; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE; UBIQUITINATION; ULTRASTRUCTURE;

AMINO ACID MOTIFS; BINDING SITES; BRCA1 PROTEIN; BREAST NEOPLASMS; CARRIER PROTEINS; CELL LINE, TUMOR; CELL NUCLEUS; DNA; DNA REPAIR; FEMALE; GENETIC VECTORS; HEK293 CELLS; HUMANS; MUTATION; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RAD51 RECOMBINASE; RECOMBINATION, GENETIC; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; UBIQUITINATION;

EID: 80053116010     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100325     Document Type: Article

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