-
1
-
-
34548186667
-
Cellular senescence: When bad things happen to good cells
-
Campisi J, d'Adda di Fagagna F. Cellular senescence: When bad things happen to good cells. Nat Rev Mol Cell Biol 2007; 8:729-40.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 729-740
-
-
Campisi, J.1
D'Adda Di Fagagna, F.2
-
2
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 1995; 92:9363-7.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
-
4
-
-
33846899456
-
Restoration of p53 function leads to tumour regression in vivo
-
DOI 10.1038/nature05541, PII NATURE05541
-
Ventura A, Kirsch DG, McLaughlin ME, Tuveson DA, Grimm J, Lintault L, et al. Restoration of p53 function leads to tumor regression in vivo. Nature 2007; 445:661-5. (Pubitemid 46232887)
-
(2007)
Nature
, vol.445
, Issue.7128
, pp. 661-665
-
-
Ventura, A.1
Kirsch, D.G.2
McLaughlin, M.E.3
Tuveson, D.A.4
Grimm, J.5
Lintault, L.6
Newman, J.7
Reczek, E.E.8
Weissleder, R.9
Jacks, T.10
-
5
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
DOI 10.1038/nature05529, PII NATURE05529
-
Xue W, Zender L, Miething C, Dickins RA, Hernando E, Krizhanovsky V, et al. Senescence and tumor clearance is triggered by p53 restoration in murine liver carcinomas. Nature 2007; 445:656-60. (Pubitemid 46232886)
-
(2007)
Nature
, vol.445
, Issue.7128
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
Dickins, R.A.4
Hernando, E.5
Krizhanovsky, V.6
Cordon-Cardo, C.7
Lowe, S.W.8
-
6
-
-
40549126830
-
Mitotic regulation by NIMA-related kinases
-
O'Regan L, Blot J, Fry AM. Mitotic regulation by NIMA-related kinases. Cell Div 2007; 2:25.
-
(2007)
Cell Div
, vol.2
, pp. 25
-
-
O'Regan, L.1
Blot, J.2
Fry, A.M.3
-
7
-
-
0042317229
-
A mitotic cascade of NIMA family kinases: Nercc1/Nek9 activates the Nek6 and Nek7 kinases
-
DOI 10.1074/jbc.M303663200
-
Belham C, Roig J, Caldwell JA, Aoyama Y, Kemp BE, Comb M, et al. A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases. J Biol Chem 2003; 278:34897-909. (Pubitemid 37102249)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.37
, pp. 34897-34909
-
-
Belham, C.1
Roig, J.2
Caldwell, J.A.3
Aoyama, Y.4
Kemp, B.E.5
Comb, M.6
Avruch, J.7
-
8
-
-
0347993081
-
The Serine/Threonine Kinase Nek6 Is Required for Cell Cycle Progression through Mitosis
-
DOI 10.1074/jbc.M308080200
-
Yin MJ, Shao L, Voehringer D, Smeal T, Jallal B. The serine/threonine kinase Nek6 is required for cell cycle progression through mitosis. J Biol Chem 2003; 278:52454-60. (Pubitemid 38035838)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.52
, pp. 52454-52460
-
-
Yin, M.-J.1
Shao, L.2
Voehringer, D.3
Smeal, T.4
Jallal, B.5
-
10
-
-
0036290004
-
Identification and characterization of Nek6 protein kinase, a potential human homolog of NIMA histone H3 kinase
-
DOI 10.1016/S0006-291X(02)00297-8, PII S0006291X02002978
-
Hashimoto Y, Akita H, Hibino M, Kohri K, Nakanishi M. Identification and characterization of Nek6 protein kinase, a potential human homolog of NIMA histone H3 kinase. Biochem Biophys Res Commun 2002; 293:753-8. (Pubitemid 34687252)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.293
, Issue.2
, pp. 753-758
-
-
Hashimoto, Y.1
Akita, H.2
Hibino, M.3
Kohri, K.4
Nakanishi, M.5
-
11
-
-
0033384625
-
Assignment of NEK6, a NIMA-related gene, to human chromosome 9q33. 3→q34.11 by radiation hybrid mapping
-
Li MZ, Yu L, Liu Q, Chu JY, Zhao SY. Assignment of NEK6, a NIMA-related gene, to human chromosome 9q33. 3→q34.11 by radiation hybrid mapping. Cytogenet Cell Genet 1999; 87:271-2.
-
(1999)
Cytogenet Cell Genet
, vol.87
, pp. 271-272
-
-
Li, M.Z.1
Yu, L.2
Liu, Q.3
Chu, J.Y.4
Zhao, S.Y.5
-
12
-
-
32344439117
-
Interaction of Pin1 with Nek6 and characterization of their expression correlation in Chinese hepatocellular carcinoma patients
-
DOI 10.1016/j.bbrc.2005.12.228, PII S0006291X05029426
-
Chen J, Li L, Zhang Y, Yang H, Wei Y, Zhang L, et al. Interaction of Pin1 with Nek6 and characterization of their expression correlation in Chinese hepatocellular carcinoma patients. Biochem Biophys Res Commun 2006; 341:1059-65. (Pubitemid 43221773)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.341
, Issue.4
, pp. 1059-1065
-
-
Chen, J.1
Li, L.2
Zhang, Y.3
Yang, H.4
Wei, Y.5
Zhang, L.6
Liu, X.7
Yu, L.8
-
13
-
-
53849112604
-
Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis
-
Takeno A, Takemasa I, Doki Y, Yamasaki M, Miyata H, Takiguchi S, et al. Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis. Br J Cancer 2008; 99:1307-15.
-
(2008)
Br J Cancer
, vol.99
, pp. 1307-1315
-
-
Takeno, A.1
Takemasa, I.2
Doki, Y.3
Yamasaki, M.4
Miyata, H.5
Takiguchi, S.6
-
14
-
-
77952916762
-
Nek6 mediates human cancer cell transformation and is a potential cancer therapeutic target
-
Nassirpour R, Shao L, Flanagan P, Abrams T, Jallal B, Smeal T, et al. Nek6 mediates human cancer cell transformation and is a potential cancer therapeutic target. Mol Cancer Res 2010; 8:717-28.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 717-728
-
-
Nassirpour, R.1
Shao, L.2
Flanagan, P.3
Abrams, T.4
Jallal, B.5
Smeal, T.6
-
15
-
-
2342431845
-
Land E1B-19K proteins inhibit p53-induced irreversible growth arrest and senescence by preventing reactive oxygen species-dependent p38 activation
-
L and E1B-19K proteins inhibit p53-induced irreversible growth arrest and senescence by preventing reactive oxygen species-dependent p38 activation. J Biol Chem 2004; 279:17765-71.
-
(2004)
J Biol Chem
, vol.279
, pp. 17765-17771
-
-
Jung, M.S.1
Jin, D.H.2
Chae, H.D.3
Kang, S.4
Kim, S.C.5
Bang, Y.J.6
-
16
-
-
0035855628
-
P53 and its homologues, p63 and p73, induce a replicative senescence through inactivation of NF-Y transcription factor
-
DOI 10.1038/sj.onc.1204748
-
Jung MS, Yun J, Chae HD, Kim JM, Kim SC, Choi TS, et al. p53 and its homologs, p63 and p73, induce a replicative senescence through inactivation of NF-Y transcription factor. Oncogene 2001; 20:5818-25. (Pubitemid 32937951)
-
(2001)
Oncogene
, vol.20
, Issue.41
, pp. 5818-5825
-
-
Jung, M.-S.1
Yun, J.2
Chae, H.-D.3
Kim, J.-M.4
Kim, S.-C.5
Choi, T.-S.6
Shin, D.Y.7
-
17
-
-
0030886015
-
Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53
-
DOI 10.1073/pnas.94.18.9648
-
Sugrue MM, Shin DY, Lee SW, Aaronson SA. Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53. Proc Natl Acad Sci USA 1997; 94:9648-53. (Pubitemid 27408116)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.18
, pp. 9648-9653
-
-
Sugrue, M.M.1
Shin, D.Y.2
Lee, S.W.3
Aaronson, S.A.4
-
18
-
-
0032532558
-
Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs
-
Wang Y, Blandino G, Oren M, Givol D. Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs. Oncogene 1998; 17:1923-30. (Pubitemid 28488460)
-
(1998)
Oncogene
, vol.17
, Issue.15
, pp. 1923-1930
-
-
Wang, Y.1
Blandino, G.2
Oren, M.3
Givol, D.4
-
19
-
-
77956250514
-
The role of NEK6 in tumor promoter-induced transformation in JB6 C141 mouse skin epidermal cells
-
Jeon YJ, Lee KY, Cho YY, Pugliese A, Kim HG, Jeong CH, et al. The role of NEK6 in tumor promoter-induced transformation in JB6 C141 mouse skin epidermal cells. J Biol Chem 2010; 285:28126-33.
-
(2010)
J Biol Chem
, vol.285
, pp. 28126-28133
-
-
Jeon, Y.J.1
Lee, K.Y.2
Cho, Y.Y.3
Pugliese, A.4
Kim, H.G.5
Jeong, C.H.6
-
23
-
-
77955747085
-
The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway
-
Albany NY
-
Korotchkina LG, Leontieva OV, Bukreeva EI, Demidenko ZN, Gudkov AV, Blagosklonny MV. The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway. Aging (Albany NY) 2010; 2:344-52.
-
(2010)
Aging
, vol.2
, pp. 344-352
-
-
Korotchkina, L.G.1
Leontieva, O.V.2
Bukreeva, E.I.3
Demidenko, Z.N.4
Gudkov, A.V.5
Blagosklonny, M.V.6
-
24
-
-
78650093044
-
P53 and aging: A fresh look at an old paradigm
-
Albany NY
-
Poyurovsky MV, Prives C. p53 and aging: A fresh look at an old paradigm. Aging (Albany NY) 2010; 2:380-2.
-
(2010)
Aging
, vol.2
, pp. 380-382
-
-
Poyurovsky, M.V.1
Prives, C.2
-
25
-
-
78650152988
-
P53, ROS and senescence in the control of aging
-
Albany NY
-
Vigneron A, Vousden KH. p53, ROS and senescence in the control of aging. Aging (Albany NY) 2010; 2:471-4.
-
(2010)
Aging
, vol.2
, pp. 471-474
-
-
Vigneron, A.1
Vousden, K.H.2
-
26
-
-
0035822699
-
Identification of the NIMA family kinases NEK6/7 as regulators of the p70 ribosomal S6 kinase
-
DOI 10.1016/S0960-9822(01)00369-4
-
Belham C, Comb MJ, Avruch J. Identification of the NIMA family kinases NEK6/7 as regulators of the p70 ribosomal S6 kinase. Curr Biol 2001; 11:1155-67. (Pubitemid 32722568)
-
(2001)
Current Biology
, vol.11
, Issue.15
, pp. 1155-1167
-
-
Belham, C.1
Comb, M.J.2
Avruch, J.3
-
27
-
-
34247640762
-
Identification of novel substrates for human checkpoint kinase Chk1 and Chk2 through genome-wide screening using a consensus Chk phosphorylation motif
-
Kim MA, Kim HJ, Brown AL, Lee MY, Bae YS, Park JI, et al. Identification of novel substrates for human checkpoint kinase Chk1 and Chk2 through genome-wide screening using a consensus Chk phosphorylation motif. Exp Mol Med 2007; 39:205-12. (Pubitemid 46683406)
-
(2007)
Experimental and Molecular Medicine
, vol.39
, Issue.2
, pp. 205-212
-
-
Kim, M.-A.1
Kim, H.-J.2
Brown, A.L.3
Lee, M.-Y.4
Bae, Y.-S.5
Park, J.-I.6
Kwak, J.-Y.7
Chung, J.H.8
Yun, J.9
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