Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis

Genes and Development

Volumn 19, Issue 18, 2005, Pages 2199-2211

  Ruvinsky, Igor ^a   Sharon, Nitzan ^a   Lerer, Tal ^a   Cohen, Hannah ^a   Stolovich Rain, Miri ^a   Nir, Tomer ^a   Dor, Yuval ^a   Zisman, Philip ^a   Meyuhas, Oded ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Cell size; Glucose intolerance; Hypoinsulinemia; Knock in mouse; TOP mRNAs; Translational control

Indexed keywords

ALANINE; GLUCOSE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PROTEIN S6; RAPAMYCIN; SERINE; TOP MRNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIVISION; CELL GROWTH; CELL SIZE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; EMBRYO; EMBRYO CELL; GENE MUTATION; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; HYPOINSULINEMIA; MOUSE; MOUSE STRAIN; NONHUMAN; PANCREAS ISLET BETA CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; RNA TRANSLATION; SUBSTITUTION REACTION; TRANSLATION REGULATION; WILD TYPE;

ALANINE; AMINO ACID SUBSTITUTION; ANIMALS; BLOOD GLUCOSE; CELL CULTURE TECHNIQUES; CELL DIVISION; CELL SIZE; CELL TRANSFORMATION, VIRAL; CELLS, CULTURED; EMBRYONIC DEVELOPMENT; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; FLUORESCENT DYES; GLUCOSE TOLERANCE TEST; HOMEOSTASIS; HOMOZYGOTE; INDOLES; INSULIN; ISLETS OF LANGERHANS; KINETICS; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; PANCREAS; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RIBOSOMAL PROTEIN S6; RNA, MESSENGER; SIROLIMUS;

EID: 24944464482     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.351605     Document Type: Article

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