Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: The role of uncoupling protein 2

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Wang, Qilong ^a   Zhang, Miao ^a   Liang, Bin ^a   Shirwany, Najeeb ^a   Zhu, Yi ^b   Zou, Ming Hui ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; ACETYL COENZYME A CARBOXYLASE; BERBERINE; CHOLESTEROL; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; MITOCHONDRIAL PROTEIN; TRANSCRIPTION FACTOR NRF1; TRIACYLGLYCEROL; UNCOUPLING PROTEIN 2; VASCULAR CELL ADHESION MOLECULE 1; 3-NITROTYROSINE; 4-HYDROXY-2-NONENAL; ALDEHYDE; AMPK ALPHA2 SUBUNIT, MOUSE; APOLIPOPROTEIN E; DRUG DERIVATIVE; ION CHANNEL; MITOCHONDRIAL UNCOUPLING PROTEIN 2; SERINE; THREONINE; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; BIOGENESIS; CARDIOVASCULAR RESPONSE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFICACY; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; TRIACYLGLYCEROL BLOOD LEVEL; UMBILICAL VEIN ENDOTHELIAL CELL; ANIMAL; AORTA; ATHEROSCLEROTIC PLAQUE; BIOSYNTHESIS; BLOOD; CHEMISTRY; DRUG EFFECT; ENZYME ACTIVATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROTEIN TRANSPORT; UPREGULATION;

MUS;

ACETYL-COA CARBOXYLASE; ALDEHYDES; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AORTA; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BERBERINE; BLOOD GLUCOSE; CHOLESTEROL; ENZYME ACTIVATION; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; ION CHANNELS; MICE; MITOCHONDRIAL PROTEINS; PHOSPHORYLATION; PLAQUE, ATHEROSCLEROTIC; PROTEIN TRANSPORT; SERINE; THREONINE; TRANSCRIPTION, GENETIC; TRIGLYCERIDES; TYROSINE; UP-REGULATION; VASCULAR CELL ADHESION MOLECULE-1;

EID: 80053196866     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025436     Document Type: Article

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