Low-dose aspirin prevents age-related endothelial dysfunction in a mouse model of physiological aging

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 294, Issue 4, 2008, Pages

  Bulckaen, Hélène ^a,b   Prévost, Gaétan ^a   Boulanger, Eric ^a   Robitaille, Géraldine ^a   Roquet, Valérie ^a   Gaxatte, Cédric ^a   Garçon, Guillaume ^c   Corman, Bruno ^a   Gosset, Pierre ^b   Shirali, Pirouz ^c   Creusy, Colette ^b   Puisieux, François ^a  

^a LILLE UNIVERSITY HOSPITAL   (France)

^b Lille Catholic Institute Hospital   (France)

^c UNIVERSITÉ DU LITTORAL CÔTE D OPALE   (France)

Author keywords

Endothelium; Intima media; Oxidative stress; Vasodilatation

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ACETYLCHOLINE; ACETYLSALICYLIC ACID; ANTIOXIDANT; MALONALDEHYDE; PHENYLEPHRINE;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTERIAL WALL THICKNESS; ARTICLE; C57BL 6 MOUSE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DRUG RESPONSE; ENDOTHELIAL DEPENDENT RELAXATION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM; HEART MUSCLE CONTRACTILITY; HEART PROTECTION; INCIDENCE; ISOLATED HEART; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARAMETER; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RISK FACTOR; VASODILATATION;

ACETYLCHOLINE; AGE FACTORS; AGING; ANIMALS; ANTIOXIDANTS; AORTA; ASPIRIN; CARDIOVASCULAR DISEASES; DEOXYGUANOSINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; OXIDATIVE STRESS; PHENYLEPHRINE; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

EID: 41749124146     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00241.2007     Document Type: Article

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