Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein

Journal of Neuroimmune Pharmacology

Volumn 8, Issue 1, 2013, Pages 94-117

  Béraud, Dawn ^a,b   Hathaway, Hannah A ^a   Trecki, Jordan ^a,e   Chasovskikh, Sergey ^c   Johnson, Delinda A ^d   Johnson, Jeffrey A ^d   Federoff, Howard J ^a,b   Shimoji, Mika ^a   Mhyre, Timothy R ^a,b   Maguire Zeiss, Kathleen A ^a  

^a GEORGETOWN UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

^c GEORGETOWN UNIVERSITY   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

^e Drug Enforcement Administration   (United States)

Author keywords

Antioxidant enzymes; Innate immunity; Microglia; Nrf2; Synucleinopathy; Toll like receptors

Indexed keywords

ALPHA SYNUCLEIN; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; INFLAMMATION; MICROGLIA; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; REVIEW;

ALKALINE PHOSPHATASE; ALPHA-SYNUCLEIN; ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; CALCIUM-BINDING PROTEINS; CELL LINE; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGE ACTIVATION; MICE; MICE, TRANSGENIC; MICROFILAMENT PROTEINS; MICROGLIA; MICROSCOPY, ATOMIC FORCE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PARKINSON DISEASE; PLACENTA; PREGNANCY; PROTEIN CONFORMATION; REAL-TIME POLYMERASE CHAIN REACTION; RNA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84874654334     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-012-9401-0     Document Type: Review

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