메뉴 건너뛰기




Volumn 57, Issue 2, 2005, Pages 168-175

Microglial activation and dopamine terminal loss in early Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; DOPAMINE TRANSPORTER; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; NALOXONE; OPIATE ANTAGONIST; TRACER;

EID: 13144258735     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.20338     Document Type: Article
Times cited : (695)

References (40)
  • 1
    • 0023874410 scopus 로고
    • Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications
    • Kish SJ, Shannak K, Hornykiewicz O. Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications. N Engl J Med 1988;318:876-880.
    • (1988) N Engl J Med , vol.318 , pp. 876-880
    • Kish, S.J.1    Shannak, K.2    Hornykiewicz, O.3
  • 2
    • 0023740773 scopus 로고
    • Rate of cell death in parkinsonism indicates active neuropathological process
    • McGeer PL, Itagaki S, Akiyama H, McGeer EG. Rate of cell death in parkinsonism indicates active neuropathological process. Ann Neurol 1988;24:574-576.
    • (1988) Ann Neurol , vol.24 , pp. 574-576
    • McGeer, P.L.1    Itagaki, S.2    Akiyama, H.3    McGeer, E.G.4
  • 3
    • 0023789193 scopus 로고
    • Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
    • McGeer PL, Itagaki S, Boyes BE, McGeer EG. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 1988;38:1285-1291.
    • (1988) Neurology , vol.38 , pp. 1285-1291
    • McGeer, P.L.1    Itagaki, S.2    Boyes, B.E.3    McGeer, E.G.4
  • 4
    • 0032738677 scopus 로고    scopus 로고
    • The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease
    • Mirza B, Hadberg H, Thomsen P, Moos T. The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease. Neuroscience 2000;95:425-432.
    • (2000) Neuroscience , vol.95 , pp. 425-432
    • Mirza, B.1    Hadberg, H.2    Thomsen, P.3    Moos, T.4
  • 5
    • 0034904508 scopus 로고    scopus 로고
    • The role of glial cells in Parkinson's disease
    • Vila M, Jackson-Lewis V, Guegan C, et al. The role of glial cells in Parkinson's disease. Curr Opin Neurol 2001;14:483-489.
    • (2001) Curr Opin Neurol , vol.14 , pp. 483-489
    • Vila, M.1    Jackson-Lewis, V.2    Guegan, C.3
  • 6
    • 0024322942 scopus 로고
    • Microglial response to 6-hydroxydopamine-induced substantia nigra lesions
    • Akiyama H, McGeer PL. Microglial response to 6-hydroxydopamine-induced substantia nigra lesions. Brain Res 1989; 489:247-253.
    • (1989) Brain Res , vol.489 , pp. 247-253
    • Akiyama, H.1    McGeer, P.L.2
  • 7
    • 0036316772 scopus 로고    scopus 로고
    • Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: Relevance to Parkinson's disease
    • Gao HM, Jiang J, Wilson B, et al. Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease. J Neurochem 2002;81:1285-1297.
    • (2002) J Neurochem , vol.81 , pp. 1285-1297
    • Gao, H.M.1    Jiang, J.2    Wilson, B.3
  • 8
    • 0037402801 scopus 로고    scopus 로고
    • Selective microglial activation in the rat rotenone model of Parkinson's disease
    • Sherer TB, Betarbet R, Kim JH, Greenamyre JT. Selective microglial activation in the rat rotenone model of Parkinson's disease. Neurosci Lett 2003;341:87-90.
    • (2003) Neurosci Lett , vol.341 , pp. 87-90
    • Sherer, T.B.1    Betarbet, R.2    Kim, J.H.3    Greenamyre, J.T.4
  • 9
    • 0037469952 scopus 로고    scopus 로고
    • Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice
    • Sugama S, Yang L, Cho BP, et al. Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice. Brain Res 2003;964:288-294.
    • (2003) Brain Res , vol.964 , pp. 288-294
    • Sugama, S.1    Yang, L.2    Cho, B.P.3
  • 10
    • 0032829070 scopus 로고    scopus 로고
    • Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine exposure
    • Langston JW, Forno LS, Tetrud J, et al. Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1, 2,3,6 tetrahydropyridine exposure. Ann Neurol 1999;46:598-605.
    • (1999) Ann Neurol , vol.46 , pp. 598-605
    • Langston, J.W.1    Forno, L.S.2    Tetrud, J.3
  • 11
    • 0242384667 scopus 로고    scopus 로고
    • Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration
    • McGeer PL, Schwab C, Parent A, Doudet D. Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine administration. Ann Neurol 2003;54:599-604.
    • (2003) Ann Neurol , vol.54 , pp. 599-604
    • McGeer, P.L.1    Schwab, C.2    Parent, A.3    Doudet, D.4
  • 12
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 1996;19:312-318.
    • (1996) Trends Neurosci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 13
    • 0343924385 scopus 로고    scopus 로고
    • Temporal changes in glial fibrillary acidic protein messenger RNA and [3H]PK11195 binding in relation to imidazoline-I2-receptor and alpha 2-adrenoceptor binding in the hippocampus following transient global forebrain ischaemia in the rat
    • Conway EL, Gundlach AL, Craven JA. Temporal changes in glial fibrillary acidic protein messenger RNA and [3H]PK11195 binding in relation to imidazoline-I2-receptor and alpha 2-adrenoceptor binding in the hippocampus following transient global forebrain ischaemia in the rat. Neuroscience 1998;82:805-817.
    • (1998) Neuroscience , vol.82 , pp. 805-817
    • Conway, E.L.1    Gundlach, A.L.2    Craven, J.A.3
  • 14
    • 0033768486 scopus 로고    scopus 로고
    • The peripheral benzodiazepine binding site in the brain in multiple sclerosis: Quantitative in vivo imaging of microglia as a measure of disease activity
    • Banati RB, Newcombe J, Gunn RN, et al. The peripheral benzodiazepine binding site in the brain in multiple sclerosis: quantitative in vivo imaging of microglia as a measure of disease activity. Brain 2000;123:2321-2337.
    • (2000) Brain , vol.123 , pp. 2321-2337
    • Banati, R.B.1    Newcombe, J.2    Gunn, R.N.3
  • 15
    • 0036459335 scopus 로고    scopus 로고
    • Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging
    • Cicchetti F, Brownell AL, Williams K, et al. Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging. Eur J Neurosci 2002;15:991-998.
    • (2002) Eur J Neurosci , vol.15 , pp. 991-998
    • Cicchetti, F.1    Brownell, A.L.2    Williams, K.3
  • 16
    • 0035845283 scopus 로고    scopus 로고
    • In-vivo measurement of activated microglia in dementia
    • Cagnin A, Brooks DJ, Kennedy AM, et al. In-vivo measurement of activated microglia in dementia. Lancet 2001;358:461-467.
    • (2001) Lancet , vol.358 , pp. 461-467
    • Cagnin, A.1    Brooks, D.J.2    Kennedy, A.M.3
  • 17
    • 0036850086 scopus 로고    scopus 로고
    • Visualising microglial activation in vivo
    • Banati RB. Visualising microglial activation in vivo. Glia 2002; 40:206-217.
    • (2002) Glia , vol.40 , pp. 206-217
    • Banati, R.B.1
  • 18
    • 0027296568 scopus 로고
    • Positron emission tomographic imaging of the dopamine transporter with 11C-WIN 35,428 reveals marked declines in mild Parkinson's disease
    • Frost JJ, Rosier AJ, Reich SG, et al. Positron emission tomographic imaging of the dopamine transporter with 11C-WIN 35,428 reveals marked declines in mild Parkinson's disease. Ann Neurol 1993;34:423-431.
    • (1993) Ann Neurol , vol.34 , pp. 423-431
    • Frost, J.J.1    Rosier, A.J.2    Reich, S.G.3
  • 19
    • 0028199038 scopus 로고
    • Dopamine terminal loss and onset of motor symptoms in MPTP-treated monkeys: A positron emission tomography study with 11C-CFT
    • Wullner U, Pakzaban P, Brownell AL, et al. Dopamine terminal loss and onset of motor symptoms in MPTP-treated monkeys: a positron emission tomography study with 11C-CFT. Exp Neurol 1994;126:305-309.
    • (1994) Exp Neurol , vol.126 , pp. 305-309
    • Wullner, U.1    Pakzaban, P.2    Brownell, A.L.3
  • 20
    • 0032963916 scopus 로고    scopus 로고
    • Alterations in binding site density of dopamine transporter in the striatum, orbitofrontal cortex, and amygdala in early Parkinson's disease: Compartment analysis for beta-CFT binding with positron emission tomography
    • Ouchi Y, Yoshikawa E, Okada H, et al. Alterations in binding site density of dopamine transporter in the striatum, orbitofrontal cortex, and amygdala in early Parkinson's disease: compartment analysis for beta-CFT binding with positron emission tomography. Ann Neurol 1999;45:601-610.
    • (1999) Ann Neurol , vol.45 , pp. 601-610
    • Ouchi, Y.1    Yoshikawa, E.2    Okada, H.3
  • 21
    • 0036624342 scopus 로고    scopus 로고
    • A new high resolution PET scanner dedicated to brain research
    • Watanabe M, Shimizu K, Omura T, et al. A new high resolution PET scanner dedicated to brain research. IEEE Trans Nucl Sci 2002;49:634-639.
    • (2002) IEEE Trans Nucl Sci , vol.49 , pp. 634-639
    • Watanabe, M.1    Shimizu, K.2    Omura, T.3
  • 22
    • 0027365136 scopus 로고
    • In vivo imaging of baboon and human dopamine transporters by positron emission tomography using [11C]WIN 35,428
    • Wong DF, Yung B, Dannals RF, et al. In vivo imaging of baboon and human dopamine transporters by positron emission tomography using [11C]WIN 35,428. Synapse 1993;15:130-142.
    • (1993) Synapse , vol.15 , pp. 130-142
    • Wong, D.F.1    Yung, B.2    Dannals, R.F.3
  • 23
    • 0026578230 scopus 로고
    • Morphometric changes of the human midbrain with normal aging: MR and stereologic findings
    • Doraiswamy PM, Na C, Husain MM, et al. Morphometric changes of the human midbrain with normal aging: MR and stereologic findings. AJNR Am J Neuroradiol 1992;13:383-386.
    • (1992) AJNR Am J Neuroradiol , vol.13 , pp. 383-386
    • Doraiswamy, P.M.1    Na, C.2    Husain, M.M.3
  • 25
    • 0032752306 scopus 로고    scopus 로고
    • Presynaptic and postsynaptic dopaminergic binding densities in the nigrostriatal and mesocortical systems in early Parkinson's disease: A double-tracer positron emission tomography study
    • Ouchi Y, Kanno T, Okada H, et al. Presynaptic and postsynaptic dopaminergic binding densities in the nigrostriatal and mesocortical systems in early Parkinson's disease: a double-tracer positron emission tomography study. Ann Neurol 1999; 46:723-731.
    • (1999) Ann Neurol , vol.46 , pp. 723-731
    • Ouchi, Y.1    Kanno, T.2    Okada, H.3
  • 26
    • 0030060961 scopus 로고    scopus 로고
    • Comparison of methods for analysis of clinical [11C]raclopride studies
    • Lammertsma AA, Bench CJ, Hume SP, et al. Comparison of methods for analysis of clinical [11C]raclopride studies. J Cereb Blood Flow Metab 1996;16:42-52.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 42-52
    • Lammertsma, A.A.1    Bench, C.J.2    Hume, S.P.3
  • 27
    • 0002646632 scopus 로고    scopus 로고
    • Parametric imaging of ligand-receptor binding in PET using a simplified reference tissue model and cluster analysis
    • Carson R, Daule M, Witherspoon P, Herscovitch P, eds. San Diego, CA: Academic Press
    • Gun R, Lammertsma AA, Cunningham VJ. Parametric imaging of ligand-receptor binding in PET using a simplified reference tissue model and cluster analysis. In: Carson R, Daule M, Witherspoon P, Herscovitch P, eds. Quantitative functional brain imaging with PET. San Diego, CA: Academic Press, 1998:401-406.
    • (1998) Quantitative Functional Brain Imaging with PET , pp. 401-406
    • Gun, R.1    Lammertsma, A.A.2    Cunningham, V.J.3
  • 28
    • 0026702955 scopus 로고
    • Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death
    • Boje KM, Arora PK. Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res 1992;587:250-256.
    • (1992) Brain Res , vol.587 , pp. 250-256
    • Boje, K.M.1    Arora, P.K.2
  • 29
    • 0032519704 scopus 로고    scopus 로고
    • Cytokine regulation of human microglial cell IL-8 production
    • Ehrlich LC, Hu S, Sheng WS, et al. Cytokine regulation of human microglial cell IL-8 production. J Immunol 1998;160:1944-1948.
    • (1998) J Immunol , vol.160 , pp. 1944-1948
    • Ehrlich, L.C.1    Hu, S.2    Sheng, W.S.3
  • 30
    • 0034982202 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha is toxic to embryonic mesencephalic dopamine neurons
    • McGuire SO, Ling ZD, Lipton JW, et al. Tumor necrosis factor alpha is toxic to embryonic mesencephalic dopamine neurons. Exp Neurol 2001;169:219-230.
    • (2001) Exp Neurol , vol.169 , pp. 219-230
    • McGuire, S.O.1    Ling, Z.D.2    Lipton, J.W.3
  • 31
    • 0035900348 scopus 로고    scopus 로고
    • Long-term transsynaptic glial responses in the human thalamus after peripheral nerve injury
    • Banati RB, Cagnin A, Brooks DJ, et al. Long-term transsynaptic glial responses in the human thalamus after peripheral nerve injury. Neuroreport 2001;12:3439-3442.
    • (2001) Neuroreport , vol.12 , pp. 3439-3442
    • Banati, R.B.1    Cagnin, A.2    Brooks, D.J.3
  • 32
    • 0036263482 scopus 로고    scopus 로고
    • Effect of simple motor performance on regional dopamine release in the striatum in parkinson disease patients and healthy subjects: A positron emission tomography study
    • Ouchi Y, Yoshikawa E, Futatsubashi M, et al. Effect of simple motor performance on regional dopamine release in the striatum in parkinson disease patients and healthy subjects: a positron emission tomography study. J Cereb Blood Flow Metab 2002;22:746-752.
    • (2002) J Cereb Blood Flow Metab , vol.22 , pp. 746-752
    • Ouchi, Y.1    Yoshikawa, E.2    Futatsubashi, M.3
  • 33
    • 0037312540 scopus 로고    scopus 로고
    • Dopamine release during sequential finger movements in health and Parkinson's disease: A PET study
    • Goerendt IK, Messa C, Lawrence AD, et al. Dopamine release during sequential finger movements in health and Parkinson's disease: a PET study. Brain 2003;126:312-325.
    • (2003) Brain , vol.126 , pp. 312-325
    • Goerendt, I.K.1    Messa, C.2    Lawrence, A.D.3
  • 34
    • 0036077851 scopus 로고    scopus 로고
    • The degenerative effect of a single intranigral injection of LPS on the dopaminergic system is prevented by dexamethasone, and not mimicked by rh-TNF-alpha, IL-1beta and IFN-gamma
    • Castano A, Herrera AJ, Cano J, Machado A. The degenerative effect of a single intranigral injection of LPS on the dopaminergic system is prevented by dexamethasone, and not mimicked by rh-TNF-alpha, IL-1beta and IFN-gamma. J Neurochem 2002;81:150-157.
    • (2002) J Neurochem , vol.81 , pp. 150-157
    • Castano, A.1    Herrera, A.J.2    Cano, J.3    Machado, A.4
  • 35
    • 0033620679 scopus 로고    scopus 로고
    • The clinical potential of cyclooxygenase-2-specific inhibitors
    • Lipsky PE. The clinical potential of cyclooxygenase-2-specific inhibitors. Am J Med 1999;106:51S-57S.
    • (1999) Am J Med , vol.106
    • Lipsky, P.E.1
  • 36
    • 0037215645 scopus 로고    scopus 로고
    • Role of microglia in inflammation-mediated neurodegenerative diseases: Mechanisms and strategies for therapeutic intervention
    • Liu B, Hong JS. Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention. J Pharmacol Exp Ther 2003;304:1-7.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 1-7
    • Liu, B.1    Hong, J.S.2
  • 37
    • 0041653249 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs and the risk of Parkinson disease
    • Chen H, Zhang SM, Hernan MA, et al. Nonsteroidal antiinflammatory drugs and the risk of Parkinson disease. Arch Neurol 2003;60:1059-1064.
    • (2003) Arch Neurol , vol.60 , pp. 1059-1064
    • Chen, H.1    Zhang, S.M.2    Hernan, M.A.3
  • 38
    • 0029811901 scopus 로고    scopus 로고
    • Arthritis and antiinflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies
    • McGeer PL, Schulzer M, McGeer EG. Arthritis and antiinflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies. Neurology 1996;47:425-432.
    • (1996) Neurology , vol.47 , pp. 425-432
    • McGeer, P.L.1    Schulzer, M.2    McGeer, E.G.3
  • 39
    • 0036686129 scopus 로고    scopus 로고
    • Immune processes in the pathogenesis of Parkinson's disease - A potential role for microglia and nitric oxide
    • Czlonkowska A, Kurkowska-Jastrzebska I, Czlonkowski A, et al. Immune processes in the pathogenesis of Parkinson's disease - a potential role for microglia and nitric oxide. Med Sci Monit 2002;8:RA165-RA177.
    • (2002) Med Sci Monit , vol.8
    • Czlonkowska, A.1    Kurkowska-Jastrzebska, I.2    Czlonkowski, A.3
  • 40
    • 0347133331 scopus 로고    scopus 로고
    • Neuroprotection in Parkinson disease: Mysteries, myths, and misconceptions
    • Schapira AH, Olanow CW. Neuroprotection in Parkinson disease: mysteries, myths, and misconceptions. JAMA 2004; 291:358-364.
    • (2004) JAMA , vol.291 , pp. 358-364
    • Schapira, A.H.1    Olanow, C.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.