α-synuclein locus duplication as a cause of familial Parkinson's disease

Lancet

Volumn 364, Issue 9440, 2004, Pages 1167-1169

  Chartier Harlin, Marie Christine ^a   Kachergus, Jennifer ^b   Roumier, Christophe ^a   Mouroux, Vincent ^a   Douay, Xavier ^c   Lincoln, Sarah ^b   Levecque, Clotilde ^a   Larvor, Lydie ^a   Andrieux, Joris ^a   Hulihan, Mary ^b   Waucquier, Nawal ^c   Defebvre, Luc ^c   Amouyel, Philippe ^a   Farrer, Matthew ^b   Destée, Alain ^c  

^a INSERM   (France)

^b MAYO GRADUATE SCHOOL   (United States)

^c LILLE UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; GENE PRODUCT;

ADULT; AGED; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DEMENTIA; DISEASE COURSE; FAMILIAL DISEASE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE DOSAGE; GENE DUPLICATION; GENE IDENTIFICATION; GENE LOCUS; GENETIC DISORDER; GENETIC PREDISPOSITION; GENETIC SCREENING; HUMAN; LEUKOCYTE; MALE; PARKINSONISM; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SNCA GENE;

EID: 4644290985     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(04)17103-1     Document Type: Article

References (5)

1. Golbe L. Alpha-synuclein in Parkinson's disease: light from two new angles. Ann Neurol. 55:2004;153-156
2. Singleton AB, Farrer M, Johnson J, et al. Alpha-synuclein locus triplication causes Parkinson's disease. Science. 302:2003;841
3. Farrer M, Kachergus J, Forno L, et al. Comparison of kindreds with familial parkinsonism and alpha-synuclein genomic multiplications. Ann Neurol. 55:2004;174-179
4. Farrer M, Destee T, Becquet E, et al. Linkage exclusion in French families with probable Parkinson's disease. Mov Disord. 15:2000;1075-1083
5. Farrer M, Maraganore DM, Lockhart P, et al. Alpha-synuclein gene haplotypes are associated with Parkinson's disease. Hum Mol Genet. 10:2001;1847-1851