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Volumn 10, Issue 3, 2011, Pages 230-240

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: A cohort study

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; TAU PROTEIN;

EID: 79951720856     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(11)70014-X     Document Type: Article
Times cited : (546)

References (42)
  • 1
    • 70549088602 scopus 로고    scopus 로고
    • Genome-wide association study reveals genetic risk underlying Parkinson's disease
    • Simon-Sanchez J, Schulte C, Bras JM, et al. Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet 2009, 41:1308-1312.
    • (2009) Nat Genet , vol.41 , pp. 1308-1312
    • Simon-Sanchez, J.1    Schulte, C.2    Bras, J.M.3
  • 2
    • 33748325848 scopus 로고    scopus 로고
    • Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease
    • Tokuda T, Salem SA, Allsop D, et al. Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease. Biochem Biophys Res Commun 2006, 349:162-166.
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 162-166
    • Tokuda, T.1    Salem, S.A.2    Allsop, D.3
  • 3
    • 49449105990 scopus 로고    scopus 로고
    • Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration
    • Mollenhauer B, Cullen V, Kahn I, et al. Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration. Exp Neurol 2008, 213:315-325.
    • (2008) Exp Neurol , vol.213 , pp. 315-325
    • Mollenhauer, B.1    Cullen, V.2    Kahn, I.3
  • 4
    • 58149469520 scopus 로고    scopus 로고
    • Cerebrospinal fluid alpha-synuclein in neurodegenerative disorders-a marker of synapse loss?
    • Ohrfelt A, Grognet P, Andreasen N, et al. Cerebrospinal fluid alpha-synuclein in neurodegenerative disorders-a marker of synapse loss?. Neurosci Lett 2009, 450:332-335.
    • (2009) Neurosci Lett , vol.450 , pp. 332-335
    • Ohrfelt, A.1    Grognet, P.2    Andreasen, N.3
  • 5
    • 58149374375 scopus 로고    scopus 로고
    • CSF alpha-synuclein levels in dementia with Lewy bodies and Alzheimer's disease
    • Noguchi-Shinohara M, Tokuda T, Yoshita M, et al. CSF alpha-synuclein levels in dementia with Lewy bodies and Alzheimer's disease. Brain Res 2009, 1251:1-6.
    • (2009) Brain Res , vol.1251 , pp. 1-6
    • Noguchi-Shinohara, M.1    Tokuda, T.2    Yoshita, M.3
  • 6
  • 7
    • 77953716788 scopus 로고    scopus 로고
    • Differential levels of alpha-synuclein, beta-amyloid42 and tau in CSF between patients with dementia with Lewy bodies and Alzheimer's disease
    • Kasuga K, Tokutake T, Ishikawa A, et al. Differential levels of alpha-synuclein, beta-amyloid42 and tau in CSF between patients with dementia with Lewy bodies and Alzheimer's disease. J Neurol Neurosurg Psychiatry 2010, 81:608-610.
    • (2010) J Neurol Neurosurg Psychiatry , vol.81 , pp. 608-610
    • Kasuga, K.1    Tokutake, T.2    Ishikawa, A.3
  • 8
    • 77950223687 scopus 로고    scopus 로고
    • DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease
    • Hong Z, Shi M, Chung KA, et al. DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. Brain 2010, 133:713-726.
    • (2010) Brain , vol.133 , pp. 713-726
    • Hong, Z.1    Shi, M.2    Chung, K.A.3
  • 9
    • 78650638645 scopus 로고    scopus 로고
    • CSF alpha-synuclein does not discriminate dementia with lewy bodies from Alzheimer's disease
    • Reesink FE, Lemstra AW, van Dijk KD, et al. CSF alpha-synuclein does not discriminate dementia with lewy bodies from Alzheimer's disease. J Alzheimers Dis 2010, 22:87-95.
    • (2010) J Alzheimers Dis , vol.22 , pp. 87-95
    • Reesink, F.E.1    Lemstra, A.W.2    van Dijk, K.D.3
  • 10
    • 78649990079 scopus 로고    scopus 로고
    • Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease
    • Tokuda T, Qureshi MM, Ardah MT, et al. Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease. Neurology 2010, 75:1766-1772.
    • (2010) Neurology , vol.75 , pp. 1766-1772
    • Tokuda, T.1    Qureshi, M.M.2    Ardah, M.T.3
  • 11
    • 77958065285 scopus 로고    scopus 로고
    • Quantification of alpha-synuclein in cerebrospinal fluid as a biomarker candidate: review of the literature and considerations for future studies
    • Mollenhauer B, El-Agnaf OM, Marcus K, Trenkwalder C, Schlossmacher MG Quantification of alpha-synuclein in cerebrospinal fluid as a biomarker candidate: review of the literature and considerations for future studies. Biomark Med 2010, 4:683-699.
    • (2010) Biomark Med , vol.4 , pp. 683-699
    • Mollenhauer, B.1    El-Agnaf, O.M.2    Marcus, K.3    Trenkwalder, C.4    Schlossmacher, M.G.5
  • 12
    • 0036209085 scopus 로고    scopus 로고
    • The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service
    • Hughes AJ, Daniel SE, Ben-Shlomo Y, Lees AJ The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service. Brain 2002, 125:861-870.
    • (2002) Brain , vol.125 , pp. 861-870
    • Hughes, A.J.1    Daniel, S.E.2    Ben-Shlomo, Y.3    Lees, A.J.4
  • 13
    • 77954362718 scopus 로고    scopus 로고
    • Does corticobasal degeneration exist? A clinicopathological re-evaluation
    • Ling H, O'Sullivan SS, Holton JL, et al. Does corticobasal degeneration exist? A clinicopathological re-evaluation. Brain 2010, 133:2045-2057.
    • (2010) Brain , vol.133 , pp. 2045-2057
    • Ling, H.1    O'Sullivan, S.S.2    Holton, J.L.3
  • 14
    • 77958031796 scopus 로고    scopus 로고
    • Imaging dopamine transporters in Parkinson's disease
    • Brooks DJ Imaging dopamine transporters in Parkinson's disease. Biomark Med 2010, 4:651-660.
    • (2010) Biomark Med , vol.4 , pp. 651-660
    • Brooks, D.J.1
  • 15
    • 77958023741 scopus 로고    scopus 로고
    • Biomarker research in Parkinson's disease: objective measures needed for patient stratification in future cause-directed trials
    • Schlossmacher MG, Mollenhauer B Biomarker research in Parkinson's disease: objective measures needed for patient stratification in future cause-directed trials. Biomark Med 2010, 4:647-650.
    • (2010) Biomark Med , vol.4 , pp. 647-650
    • Schlossmacher, M.G.1    Mollenhauer, B.2
  • 16
    • 77957264418 scopus 로고    scopus 로고
    • The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia
    • Schulz-Schaeffer WJ The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia. Acta Neuropathol 2010, 120:131-143.
    • (2010) Acta Neuropathol , vol.120 , pp. 131-143
    • Schulz-Schaeffer, W.J.1
  • 17
    • 21244457198 scopus 로고    scopus 로고
    • Consensus paper of the WFSBP Task Force on Biological Markers of Dementia: the role of CSF and blood analysis in the early and differential diagnosis of dementia
    • Wiltfang J, Lewczuk P, Riederer P, et al. Consensus paper of the WFSBP Task Force on Biological Markers of Dementia: the role of CSF and blood analysis in the early and differential diagnosis of dementia. World J Biol Psychiatry 2005, 6:69-84.
    • (2005) World J Biol Psychiatry , vol.6 , pp. 69-84
    • Wiltfang, J.1    Lewczuk, P.2    Riederer, P.3
  • 18
    • 0023887031 scopus 로고
    • Accuracy in the clinical diagnosis of parkinsonian syndromes
    • Gibb WR Accuracy in the clinical diagnosis of parkinsonian syndromes. Postgrad Med J 1988, 64:345-351.
    • (1988) Postgrad Med J , vol.64 , pp. 345-351
    • Gibb, W.R.1
  • 20
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 21
    • 34447322271 scopus 로고    scopus 로고
    • Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria
    • Dubois B, Feldman HH, Jacova C, et al. Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria. Lancet Neurol 2007, 6:734-746.
    • (2007) Lancet Neurol , vol.6 , pp. 734-746
    • Dubois, B.1    Feldman, H.H.2    Jacova, C.3
  • 22
    • 52449086856 scopus 로고    scopus 로고
    • Second consensus statement on the diagnosis of multiple system atrophy
    • Gilman S, Wenning GK, Low PA, et al. Second consensus statement on the diagnosis of multiple system atrophy. Neurology 2008, 71:670-676.
    • (2008) Neurology , vol.71 , pp. 670-676
    • Gilman, S.1    Wenning, G.K.2    Low, P.A.3
  • 23
    • 0016823810 scopus 로고
    • " Mini-mental state" A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR " Mini-mental state" A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975, 12:189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 24
    • 34047223232 scopus 로고    scopus 로고
    • DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers
    • Lippa CF, Duda JE, Grossman M, et al. DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers. Neurology 2007, 68:812-819.
    • (2007) Neurology , vol.68 , pp. 812-819
    • Lippa, C.F.1    Duda, J.E.2    Grossman, M.3
  • 27
    • 8944226575 scopus 로고    scopus 로고
    • Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-SPSP international workshop
    • Litvan I, Agid Y, Calne D, et al. Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-SPSP international workshop. Neurology 1996, 47:1-9.
    • (1996) Neurology , vol.47 , pp. 1-9
    • Litvan, I.1    Agid, Y.2    Calne, D.3
  • 28
    • 77957220702 scopus 로고    scopus 로고
    • CSF amyloid β 1-42 predicts cognitive decline in Parkinson disease
    • Siderowf A, Xie SX, Hurtig H, et al. CSF amyloid β 1-42 predicts cognitive decline in Parkinson disease. Neurology 2010, 75:1055-1061.
    • (2010) Neurology , vol.75 , pp. 1055-1061
    • Siderowf, A.1    Xie, S.X.2    Hurtig, H.3
  • 29
    • 33644832047 scopus 로고    scopus 로고
    • Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans
    • Fagan AM, Mintun MA, Mach RH, et al. Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans. Ann Neurol 2006, 59:512-519.
    • (2006) Ann Neurol , vol.59 , pp. 512-519
    • Fagan, A.M.1    Mintun, M.A.2    Mach, R.H.3
  • 30
    • 49449102642 scopus 로고    scopus 로고
    • GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein
    • Scherzer CR, Grass JA, Liao Z, et al. GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein. Proc Natl Acad Sci USA 2008, 105:10907-10912.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10907-10912
    • Scherzer, C.R.1    Grass, J.A.2    Liao, Z.3
  • 31
    • 77949423619 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
    • Blennow K, Hampel H, Weiner M, Zetterberg H Cerebrospinal fluid and plasma biomarkers in Alzheimer disease. Nat Rev Neurol 2010, 6:131-144.
    • (2010) Nat Rev Neurol , vol.6 , pp. 131-144
    • Blennow, K.1    Hampel, H.2    Weiner, M.3    Zetterberg, H.4
  • 32
    • 33748163112 scopus 로고    scopus 로고
    • Beta-amlyoid 1-42 and tau-protein in cerebrospinal fluid of patients with Parkinson's disease dementia
    • Mollenhauer B, Trenkwalder C, von Ahsen N, et al. Beta-amlyoid 1-42 and tau-protein in cerebrospinal fluid of patients with Parkinson's disease dementia. Dement Geriatr Cogn Disord 2006, 22:200-208.
    • (2006) Dement Geriatr Cogn Disord , vol.22 , pp. 200-208
    • Mollenhauer, B.1    Trenkwalder, C.2    von Ahsen, N.3
  • 33
    • 36649029701 scopus 로고    scopus 로고
    • Peirce, Youden and the receiver operating characteristic curves
    • Baker SG, Kramer BS Peirce, Youden and the receiver operating characteristic curves. Am Stat 2007, 61:343-346.
    • (2007) Am Stat , vol.61 , pp. 343-346
    • Baker, S.G.1    Kramer, B.S.2
  • 35
    • 57349093766 scopus 로고    scopus 로고
    • Levodopa for the treatment of Parkinson's disease
    • Lewitt PA Levodopa for the treatment of Parkinson's disease. N Engl J Med 2008, 359:2468-2476.
    • (2008) N Engl J Med , vol.359 , pp. 2468-2476
    • Lewitt, P.A.1
  • 36
    • 77952477706 scopus 로고    scopus 로고
    • Inter-laboratory variation in cerebrospinal fluid biomarkers for Alzheimer's disease: united we stand, divided we fall
    • Mattsson N, Blennow K, Zetterberg H Inter-laboratory variation in cerebrospinal fluid biomarkers for Alzheimer's disease: united we stand, divided we fall. Clin Chem Lab Med 2010, 48:603-607.
    • (2010) Clin Chem Lab Med , vol.48 , pp. 603-607
    • Mattsson, N.1    Blennow, K.2    Zetterberg, H.3
  • 39
    • 69149089854 scopus 로고    scopus 로고
    • Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein
    • Desplats P, Lee HJ, Bae EJ, et al. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Proc Natl Acad Sci USA 2009, 106:13010-13015.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13010-13015
    • Desplats, P.1    Lee, H.J.2    Bae, E.J.3
  • 40
    • 77958024334 scopus 로고    scopus 로고
    • Biomarkers in Parkinson's disease: a funder's perspective
    • Frasier M, Chowdhury S, Eberling J, et al. Biomarkers in Parkinson's disease: a funder's perspective. Biomark Med 2010, 4:723-729.
    • (2010) Biomark Med , vol.4 , pp. 723-729
    • Frasier, M.1    Chowdhury, S.2    Eberling, J.3
  • 41
    • 77951234348 scopus 로고    scopus 로고
    • Distinguishing SWEDDs patients with asymmetric resting tremor from Parkinson's disease: a clinical and electrophysiological study
    • Schwingenschuh P, Ruge D, Edwards MJ, et al. Distinguishing SWEDDs patients with asymmetric resting tremor from Parkinson's disease: a clinical and electrophysiological study. Mov Disord 2010, 25:560-569.
    • (2010) Mov Disord , vol.25 , pp. 560-569
    • Schwingenschuh, P.1    Ruge, D.2    Edwards, M.J.3
  • 42
    • 84886104938 scopus 로고    scopus 로고
    • Identifying targets in alpha-synuclein metabolism to treat Parkinson's and related disorders
    • John Wiley and Son, Hoboken, NJ, M. Ramirez-Alvarado, J.W. Kelly, C.M. Dobson (Eds.)
    • Tomlinson J, Cullen V, Schlossmacher MG Identifying targets in alpha-synuclein metabolism to treat Parkinson's and related disorders. Protein misfolding diseases: current and emerging principles and therapies 2010, 817-841. John Wiley and Son, Hoboken, NJ. M. Ramirez-Alvarado, J.W. Kelly, C.M. Dobson (Eds.).
    • (2010) Protein misfolding diseases: current and emerging principles and therapies , pp. 817-841
    • Tomlinson, J.1    Cullen, V.2    Schlossmacher, M.G.3


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