Effect of the overexpression of wild-type or mutant α-synuclein on cell susceptibility to insult

Journal of Neurochemistry

Volumn 76, Issue 4, 2001, Pages 998-1009

  Lee, Moonhee ^a   Hyun, Dong Hoon ^a   Halliwell, Barry ^a,b   Jenner, Peter ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Apoptosis; Familial Parkinson's disease; Mutant synuclein; Oxidative stress; Wild type synuclein

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 3 NITROTYROSINE; 8 HYDROXYGUANINE; ALPHA SYNUCLEIN; CARBONYL DERIVATIVE; GLUTATHIONE; HYDROGEN PEROXIDE; LACTACYSTIN; STAUROSPORINE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; FAMILIAL DISEASE; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; SUBSTANTIA NIGRA;

1-METHYL-4-PHENYLPYRIDINIUM; ALDEHYDES; ALPHA-SYNUCLEIN; CELL DIVISION; CELL LINE; CELL SURVIVAL; CLONE CELLS; CULTURE MEDIA, SERUM-FREE; ENZYME INHIBITORS; GENE EXPRESSION; GLUTATHIONE; GUANINE; HUMANS; HYDROGEN PEROXIDE; KETONES; LIPID PEROXIDATION; MITOCHONDRIA; MUTATION; NERVE TISSUE PROTEINS; NEUROBLASTOMA; OXIDANTS; OXIDATIVE STRESS; PARKINSONIAN DISORDERS; SYNUCLEINS; TERATOCARCINOMA; TRANSFECTION; TYROSINE;

EID: 0035109909     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00149.x     Document Type: Article

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