Microglial reaction in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson's disease mice model

Neurodegeneration

Volumn 5, Issue 2, 1996, Pages 137-143

  Członkowska, Anna ^a   Kohutnicka, Małgorzata ^b   Kurkowska Jastrzȩbska, Iwona ^b   Członkowski, Andrzej ^b  

^a INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Poland)

^b MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

Dopaminergic neurons; Microglia; Mouse; MPTP; Parkinson's disease model

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL STRUCTURE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; MALE; MICROGLIA; MOUSE; NONHUMAN; PARKINSON DISEASE; PERIKARYON; PRIORITY JOURNAL; SUBSTANTIA NIGRA;

EID: 0030175757     PISSN: 10558330     EISSN: None     Source Type: Journal    
DOI: 10.1006/neur.1996.0020     Document Type: Article

References (48)

1. Arai N, Misugi K, Goshima Y, Misu Y (1990) Evaluation of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated C57 black mouse model for parkinsonism. Brain Res 515:57-63
2. Banati RB, Gehrmann J, Schubert P, Kreutzberg GW (1993) Cytotoxicity of microglia. Glia 7:111-118
3. Bieganowska K, Członkowska A, Bidziński A, Mierzewska H, Korlak J (1993) Immunological changes in the MPTP-induced Parkinson's disease mouse model. J Neuroimmunol 42:33-38
4. Burns RS, Chiueh CC, Markey SP, Ebert MH, Jacobowitz DM, Kopin IJ (1983) A primate model of parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc Natl Acad Sci USA 80:4546-4550
5. Chadi GM, Moller A, Rosén L, Janson AM, Agnati LA, Goldstein M, Ögren S-O, Pettersson RF, Fuxe K (1993) Protective actions of human recombinant basic fibroblast growth factor on MPTP-lesioned nigrostriatal dopamine neurons after intraventricular infusion. Exp Brain Res 97:145-158
6. Deutch AY, Elsworth JD, Goldstein M, Fuxe K, Redmond DE Jr, Sladeck JR Jr, Roth RH (1986) Preferential vulnerability of A8 dopamine neurons in the primate to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neurosci Lett 68:51-56
7. Fagan AM, Gage FH (1990) Cholinergic sprouting in the hippocampus: a proposed role for IL-1. Exp Neurol 110:105-120
8. Francis JW, Visger J, Markelonis J, Oh TH (1995) Neuroglial responses to the dopaminergic neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse striatum. Neurotoxicol Teratol 17:7-12
9. Gehrmann J, Schoen SW, Kreutzberg GW (1991) Lesion of the rat enthorinal cortex leads to a rapid microglial reaction in the deafferented dentate gyrus. A light and electron microscopical study. Acta Neuropathol 82:442-455
10. Gehrmann J, Gold R, Linington C, Lannes-Vieira J, Wekerle H, Kreutzberg GW (1992) Spinal cord microglia in experimental allergic neuritis: evidence for fast and remote action. Lab Invest 67:100-113
11. Gehrmann J, Gold R, Linington C, Lannes-Vieira J. Wekerle H, Kreutzberg GW (1993) The microglia involvement in the experimental autoimmunoinflammation of the central and peripheral nervous system. Glia 7:50-59
12. Giulian D, Lachman LB (1985) Interleukin-1 stimulation of astroglial proliferation after brain injury. Science 228:497-499
13. Giulian D (1993) Reactive glia as rivals in regulating neuronal survival. Glia 7:102-110
14. Giulian D, Vaca K, Corpuz M (1993) Brain glia release factors with opposing actîons upon neuronal survival. J Neurosci 13:29-37
15. Graeber MB, Tetzlaff W, Streit WJ, Kreutzberg GW (1988) Microglial cells but not astrocytes undergo mitosis following rat facial nerve axotomy. Neurosci Lett 85:317-321
16. Hama T, Kushima Y, Miyamoto M, Kubota M, Takei N, Hatanaka H (1991) Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholinergic neurones from post-natal, two-weeks-old rats in cultures. Neuroscience 40:445-452
17. Heikkila RE, Hess A, Duvoisin RC (1984) Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice. Science 224:1451-1453
18. Heikkila RE, Sonsalla PK (1992) The MPTP-treated mouse as a model of parkinsonism: how good is it? Neurochem Int 20:299S-303S
19. Jenner P, Rupniak NMJ, Rose S, Kelly E, Kilpatrick G, Less A, Marsden CD (1984) 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced parkinsonism in the common marmoset. Neurosci Lett 50:85-90
20. Kitamura Y, Itano Y, Kubo T, Namura Y (1994) Suppressive effect of FK-506, a novel immunosuppressant, against MPTP-induced dopamine depletion in the striatum of young C57B1/6 mice. Neuroimmunol 50:221-224
21. Kitt CA, Cork LC, Eidelberg E, Joh TH, Price DL (1987) Injury of catecholaminergic neurons after acute exposure to MPTP. A TH immunocytochemical study in the monkey. Ann NY Acad Sci 495:730-731
22. Langston JW, Forno LS, Rebert CS, Irwin I (1984) Selective nigral toxicity after administration of 1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine (MPTP) in the squirrel monkey. Brain Res 292: 390-394
23. Linder JC, Klemfuss H, Groves PM (1987) Acute ultrastructural and behavioral effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice. Neurosci Lett 82:221-226
24. Lindholm D, Heumann R, Meyer M, Thoenen H (1987) Interleukin-1 regulates synthesis of the nerve growth factor in non-neuronal cells of rat sciatic nerve. Nature 330:658-659
25. McGeer PL, Itagaki S, Boyes BE, McGeer EG (1988) Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 38:1285-1291
26. Mori S, Fujitake J, Kuno S, Sano Y (1988) Immunohistochemical evaluation of the neurotoxic effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on dopaminergic nigrostriatal neurons of young adult mice using dopamine and tyrosine hydroxylase antibodies. Neurosci Lett 90:57-62
27. Morioka T, Kalehua AN, Streit WJ (1991) The microglial reaction in the rat dorsal hippocampus following transient forebrain ischemia. J Cereb Blood Flow Metab 11:966-997
28. Morioka T, Kalehua AN Streit WJ (1992) Progressive expression of immunomolecules on microglial cells in rat dorsal hippocampus following transient forebrain ischemia. Acta Neuropathol (Berl) 83:149-157
29. Nakata N, Kato H, Kogura K (1993) Protective effects of brain fibroblast growth factor against hippocampal neuronal damage following cerebral ischemia in the gerbil. Brain Res 605:458-464
30. O'Callaghan JP, Miller DB, Reinhard JF Jr (1990) Characterization of the origins of astrocyte response to injury using the dopaminergie neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Brain Res 521:73-80
31. Ogawa M, Araki M, Niijima K, Yoshida M (1992) Microglial reactions in the inferior olive and its tract induced by intraperitoneal injection of 3-acetylpyridine in the rat. Neurodegeneration 1:37-43
32. Parisi JE, Burns RS (1986) The neuropathology of MPTP-induced parkinsonism in man and experimental animals. In Markey SP, Castagnoli N Jr, Trevor AJ, Kopin IJ (eds). MPTP: A neurotoxin producing a parkinsonian syndrome, Academie Press, Orlando, pp 141-148
33. Perlmutter LS, Scott SA, Barrón, Chui HC (1992) MCH class II-positive microglia in human brain: association with Alzheimer lesions. J Neurosci Res 33:549-558
34. Perry VH, Gordon S (1988) Microphages and microglia in the nervous system. Trends Neurosci 11:273-277
35. Pileblad E, Fornstedt D, Clark D, Carlsson A (1985) Acute effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on dopamine metabolism in mouse and rat striatum. J Pharm Pharmacol 37:707-712
36. Ricaurte GA, Irwin I, Forno LS, DeLanney LE, Langston E, Langston JW (1987) Aging and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced degeneration of dopaminergic neurons in the substantia nigra. Brain Res 403:43-51
37. Rich JB, Rasmusson DX, Folstein MF, Carson KA, Kawas C, Brandt J (1995) Nonsteroidal anti-inflammatory drugs in Alzheimer's disease. Neurology 45:51-55
38. Sato T, Nakamura S, Taga T, Matsuda T, Hirano T, Kishimoto T, Kaziro T (1988) Induction of neuronal differentiation of PC12 cells by B cell stimulatory factor 2 (interleukin-6). Mol Cell Biol 8:3546-3549
39. Schneider JS, Markham CH (1986) Neurotoxic effects of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the cat. Tyrosine hydroxylase immunohistochemistry. Brain Res 373:258-267
40. Schultz W, Studer A, Jonsson G, Sundström E, Mefford I (1985) Deficits in behavioral initiation and execution processes in monkeys with 1-methyl-4phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism. Neurosci Lett 59:225-232
41. Seniuk NA, Tatton WG, Greenwood CE (1990) Dose dependent destruction of the coeruleus-cortical and nigral-striatal projections by MPTP. Brain Res 527:7-20
42. Shigeno T, Mima T, Takakura K, Graham DT, Kato G, Hashimoto Y, Furukawa S (1991) Amelioration of delayed neuronal death in the hippocampus by nerve growth factor. J Neurosci 11:2914-2919
43. Streit WJ, Kreutzberg GW (1987) Lectin binding by resting and reactive microglia. J Neurocytol 16:249-260
44. 4). J Histochem Cytochem 38:1683-1686
45. Stromberg I, Bjorklund H, Dahl D, Jonnson G, Sundstrom E, Olson L (1986) Astrocytic responses to dopaminergic denervations by 6-hydroxyl-dopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine as evidenced by glial fibrillary acidic protein immunohistochemistry. Brain Res Bull 17:225-236
46. Sundström G, Luthman J, Goldstein M, Jonsson (1988) Time course of MPTP induced degeneration in the nigrostriatal dopamine system in C57B1/6 mice. Brain Res Bull 21:257-263
47. Tatton WG, Greenwood CE, Verrier MC, Holland DP, Kwan MN Biddle FE (1991) Different rates of age-related loss for four murine monoaminergic neuronal populations. Neurobiol Aging 12:543-556
48. +)-induced brain injury. Cell Mol Neurobiol 14:99-104