메뉴 건너뛰기




Volumn 14, Issue 1, 2011, Pages 137-167

Heme oxygenase in the regulation of vascular biology: From molecular mechanisms to therapeutic opportunities

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BILIVERDIN; CARBON MONOXIDE; CHEMOKINE; CYTOKINE; FERRITIN; FERROUS ION; HEAT SHOCK PROTEIN; HEME OXYGENASE; HEME OXYGENASE 1; HEME OXYGENASE 2; MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR BACH1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 78649477021     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2010.3153     Document Type: Review
Times cited : (193)

References (300)
  • 1
    • 41149177025 scopus 로고    scopus 로고
    • Pharmacological and clinical aspects of heme oxygenase
    • Abraham NG and Kappas A. Pharmacological and clinical aspects of heme oxygenase. Pharmacol Rev 60: 79-127, 2008.
    • (2008) Pharmacol Rev , vol.60 , pp. 79-127
    • Abraham, N.G.1    Kappas, A.2
  • 2
    • 0141608946 scopus 로고    scopus 로고
    • Heme oxyge-nase-1 attenuates glucose-mediated cell growth arrest and apoptosis in human microvessel endothelial cells
    • Abraham NG, Kushida T, McClung J, Weiss M, Quan S, Lafaro R, Darzynkiewicz Z, and Wolin M. Heme oxyge-nase-1 attenuates glucose-mediated cell growth arrest and apoptosis in human microvessel endothelial cells. Circ Res 93: 507-514, 2003.
    • (2003) Circ Res , vol.93 , pp. 507-514
    • Abraham, N.G.1    Kushida, T.2    McClung, J.3    Weiss, M.4    Quan, S.5    Lafaro, R.6    Darzynkiewicz, Z.7    Wolin, M.8
  • 5
    • 33646401393 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the anti-inflammatory actions of 2'-hydroxychalcone in RAW 264.7 murine macrophages
    • Abuarqoub H, Foresti R, Green CJ, and Motterlini R. Heme oxygenase-1 mediates the anti-inflammatory actions of 2'-hydroxychalcone in RAW 264.7 murine macrophages. Am J Physiol Cell Physiol 290: C1092-C1099, 2006.
    • (2006) Am J Physiol Cell Physiol , vol.290
    • Abuarqoub, H.1    Foresti, R.2    Green, C.J.3    Motterlini, R.4
  • 6
    • 0034065989 scopus 로고    scopus 로고
    • Heme oxygenase-1 is upre-gulated in the kidney of angiotensin II-induced hypertensive rats: Possible role in renoprotection
    • Aizawa T, Ishizaka N, Taguchi J, Nagai R, Mori I, Tang SS, Ingelfinger JR, and Ohno M. Heme oxygenase-1 is upre-gulated in the kidney of angiotensin II-induced hypertensive rats: possible role in renoprotection. Hypertension 35: 800-806, 2000.
    • (2000) Hypertension , vol.35 , pp. 800-806
    • Aizawa, T.1    Ishizaka, N.2    Taguchi, J.3    Nagai, R.4    Mori, I.5    Tang, S.S.6    Ingelfinger, J.R.7    Ohno, M.8
  • 7
    • 33846924300 scopus 로고    scopus 로고
    • How many transcription factors does it take to turn on the heme oxygenase-1 gene?
    • Alam J and Cook JL. How many transcription factors does it take to turn on the heme oxygenase-1 gene? Am J Respir Cell Mol Biol 36: 166-174, 2007.
    • (2007) Am J Respir Cell Mol Biol , vol.36 , pp. 166-174
    • Alam, J.1    Cook, J.L.2
  • 8
    • 0026788471 scopus 로고
    • Distal AP-1 binding sites mediate basal level enhancement and TPA induction of the mouse heme oxygenase-1 gene
    • Alam J and Den Z. Distal AP-1 binding sites mediate basal level enhancement and TPA induction of the mouse heme oxygenase-1 gene. J Biol Chem 267: 21894-21900, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 21894-21900
    • Alam, J.1    Den, Z.2
  • 10
    • 67650523965 scopus 로고    scopus 로고
    • Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothe-lium exposed to laminar shear stress and impaired by disturbed flow
    • Ali F, Zakkar M, Karu K, Lidington EA, Hamdulay SS, Boyle JJ, Zloh M, Bauer A, Haskard DO, Evans PC, and Mason JC. Induction of the cytoprotective enzyme heme oxygenase-1 by statins is enhanced in vascular endothe-lium exposed to laminar shear stress and impaired by disturbed flow. J Biol Chem 284: 18882-18892, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 18882-18892
    • Ali, F.1    Zakkar, M.2    Karu, K.3    Lidington, E.A.4    Hamdulay, S.S.5    Boyle, J.J.6    Zloh, M.7    Bauer, A.8    Haskard, D.O.9    Evans, P.C.10    Mason, J.C.11
  • 12
    • 20444456655 scopus 로고    scopus 로고
    • Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: Role of mitogen-activated protein kinases and Nrf2
    • Anwar AA, Li FY, Leake DS, Ishii T, Mann GE, and Siow RC. Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2. Free Radic Biol Med 39: 227-236, 2005.
    • (2005) Free Radic Biol Med , vol.39 , pp. 227-236
    • Anwar, A.A.1    Li, F.Y.2    Leake, D.S.3    Ishii, T.4    Mann, G.E.5    Siow, R.C.6
  • 13
    • 38949110010 scopus 로고    scopus 로고
    • Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages
    • Ashino T, Yamanaka R, Yamamoto M, Shimokawa H, Se-kikawa K, Iwakura Y, Shioda S, Numazawa S, and Yoshida T. Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages. Mol Immunol 45: 2106-2115, 2008.
    • (2008) Mol Immunol , vol.45 , pp. 2106-2115
    • Ashino, T.1    Yamanaka, R.2    Yamamoto, M.3    Shimokawa, H.4    Se-Kikawa, K.5    Iwakura, Y.6    Shioda, S.7    Numazawa, S.8    Yoshida, T.9
  • 15
    • 23444454955 scopus 로고    scopus 로고
    • Heme oxygenase-1: A therapeutic amplification funnel
    • Bach FH. Heme oxygenase-1: a therapeutic amplification funnel. FASEB J 19: 1216-1219, 2005.
    • (2005) FASEB J , vol.19 , pp. 1216-1219
    • Bach, F.H.1
  • 17
    • 0025819677 scopus 로고
    • Exposure of endothelial cells to free heme potentiates damage mediated by granulocytes and toxic oxygen species
    • Balla G, Vercellotti G, Muller-Eberhard U, Eaton JW, and Jacob HS. Exposure of endothelial cells to free heme potentiates damage mediated by granulocytes and toxic oxygen species. Lab Invest 64: 648-655, 1991.
    • (1991) Lab Invest , vol.64 , pp. 648-655
    • Balla, G.1    Vercellotti, G.2    Muller-Eberhard, U.3    Eaton, J.W.4    Jacob, H.S.5
  • 18
    • 0027358877 scopus 로고
    • Endothelial-cell heme uptake from heme proteins: Induction of sensitization and desensitization to oxidant damage
    • Balla J, Jacob HS, Balla G, Nath K, Eaton JW, and Vercellotti GM. Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage. Proc Natl Acad Sci USA 90: 9285-9289, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9285-9289
    • Balla, J.1    Jacob, H.S.2    Balla, G.3    Nath, K.4    Eaton, J.W.5    Vercellotti, G.M.6
  • 24
    • 0035716135 scopus 로고    scopus 로고
    • Nitric oxide inhibits endothelial IL-1beta-induced ICAM-1 gene expression at the transcriptional level decreasing Sp1 and AP-1 activity
    • Berendji-Grun D, Kolb-Bachofen V, and Kroncke KD. Nitric oxide inhibits endothelial IL-1beta-induced ICAM-1 gene expression at the transcriptional level decreasing Sp1 and AP-1 activity. Mol Med 7: 748-754, 2001.
    • (2001) Mol Med , vol.7 , pp. 748-754
    • Berendji-Grun, D.1    Kolb-Bachofen, V.2    Kroncke, K.D.3
  • 25
    • 0029883764 scopus 로고    scopus 로고
    • The role of oxidized lipopro-teins in atherogenesis
    • Berliner JA and Heinecke JW. The role of oxidized lipopro-teins in atherogenesis. Free Radic Biol Med 20: 707-727, 1996.
    • (1996) Free Radic Biol Med , vol.20 , pp. 707-727
    • Berliner, J.A.1    Heinecke, J.W.2
  • 32
    • 0035980110 scopus 로고    scopus 로고
    • Hsp90 ensures the transition from the early Ca2\+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells
    • Brouet A, Sonveaux P, Dessy C, Balligand JL, and Feron O. Hsp90 ensures the transition from the early Ca2\+-dependent to the late phosphorylation- dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells. J Biol Chem 276: 32663-32669, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 32663-32669
    • Brouet, A.1    Sonveaux, P.2    Dessy, C.3    Balligand, J.L.4    Feron, O.5
  • 33
    • 0025320091 scopus 로고
    • In vivo binding of carbon monoxide to cytochrome c oxidase in rat brain
    • Brown SD and Piantadosi CA. In vivo binding of carbon monoxide to cytochrome c oxidase in rat brain. J Appl Physiol 68: 604-610, 1990.
    • (1990) J Appl Physiol , vol.68 , pp. 604-610
    • Brown, S.D.1    Piantadosi, C.A.2
  • 34
    • 33746874131 scopus 로고    scopus 로고
    • Dual role of VEGF-induced heme-oxygenase-1 in angiogenesis
    • Bussolati B and Mason JC. Dual role of VEGF-induced heme-oxygenase-1 in angiogenesis. Antiox Redox Signal 8: 1153-1163, 2006.
    • (2006) Antiox Redox Signal , vol.8 , pp. 1153-1163
    • Bussolati, B.1    Mason, J.C.2
  • 35
    • 1642581763 scopus 로고    scopus 로고
    • Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: Induction of angiogenesis and inhibition of leukocytic infiltration
    • Bussolati B, Ahmed A, Pemberton H, Landis RC, Di Carlo F, Haskard DO, and Mason JC. Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: induction of angiogenesis and inhibition of leukocytic infiltration. Blood 103: 761-766, 2004.
    • (2004) Blood , vol.103 , pp. 761-766
    • Bussolati, B.1    Ahmed, A.2    Pemberton, H.3    Landis, R.C.4    Di Carlo, F.5    Haskard, D.O.6    Mason, J.C.7
  • 36
    • 67649213915 scopus 로고    scopus 로고
    • Vitagenes, cellular stress response, and acet-ylcarnitine: Relevance to hormesis
    • Calabrese V, Cornelius C, Dinkova-Kostova AT, and Ca-labrese EJ. Vitagenes, cellular stress response, and acet-ylcarnitine: relevance to hormesis. Biofactors 35: 146-160, 2009.
    • (2009) Biofactors , vol.35 , pp. 146-160
    • Calabrese, V.1    Cornelius, C.2    Dinkova-Kostova, A.T.3    Ca-Labrese, E.J.4
  • 42
    • 0029392368 scopus 로고
    • Induction of heme oxygenase-1 gene expression by lipo-polysaccharide is mediated by AP-1 activation
    • Camhi SL, Alam J, Otterbein L, Sylvester SL, and Choi AM. Induction of heme oxygenase-1 gene expression by lipo-polysaccharide is mediated by AP-1 activation. Am J Respir Cell Mol Biol 13: 387-398, 1995.
    • (1995) Am J Respir Cell Mol Biol , vol.13 , pp. 387-398
    • Camhi, S.L.1    Alam, J.2    Otterbein, L.3    Sylvester, S.L.4    Choi, A.M.5
  • 43
    • 38349171767 scopus 로고    scopus 로고
    • Carbon monoxide liberated from carbon monoxide-releasing molecule CORM-2 attenuates inflammation in the liver of septic mice
    • Cepinskas G, Katada K, Bihari A, and Potter RF. Carbon monoxide liberated from carbon monoxide-releasing molecule CORM-2 attenuates inflammation in the liver of septic mice. Am J Physiol Gastrointest Liver Physiol 294: G184-G191, 2008.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294
    • Cepinskas, G.1    Katada, K.2    Bihari, A.3    Potter, R.F.4
  • 46
    • 3042783328 scopus 로고    scopus 로고
    • Water-soluble carbon monoxide-releasing molecules: Helping to elucidate the vascular activity of the silent killer
    • Chatterjee PK. Water-soluble carbon monoxide-releasing molecules: helping to elucidate the vascular activity of the "silent killer." Br J Pharmacol 142: 391-393, 2004.
    • (2004) Br J Pharmacol , vol.142 , pp. 391-393
    • Chatterjee, P.K.1
  • 48
    • 26244455871 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors upregulate heme oxygenase-1 expression in murine RAW264.7 macrophages via ERK, p38 MAPK and protein kinase G pathways
    • Chen JC, Huang KC, and Lin WW. HMG-CoA reductase inhibitors upregulate heme oxygenase-1 expression in murine RAW264.7 macrophages via ERK, p38 MAPK and protein kinase G pathways. Cell Signal 18: 32-39, 2006.
    • (2006) Cell Signal , vol.18 , pp. 32-39
    • Chen, J.C.1    Huang, K.C.2    Lin, W.W.3
  • 50
    • 16344369210 scopus 로고    scopus 로고
    • Study on changes of heme oxygenase-1 expression in patients with coronary heart disease
    • Chen SM, Li YG, and Wang DM. Study on changes of heme oxygenase-1 expression in patients with coronary heart disease. Clin Cardiol 28: 197-201, 2005.
    • (2005) Clin Cardiol , vol.28 , pp. 197-201
    • Chen, S.M.1    Li, Y.G.2    Wang, D.M.3
  • 52
    • 0346727582 scopus 로고    scopus 로고
    • Heme oxygenase-1 gene promotor micro-satellite polymorphism is associated with angiographic restenosis after coronary stenting
    • Chen YH, Chau LY, Lin MW, Chen LC, Yo MH, Chen JW, and Lin SJ. Heme oxygenase-1 gene promotor micro-satellite polymorphism is associated with angiographic restenosis after coronary stenting. Eur Heart J 25: 39-47, 2004.
    • (2004) Eur Heart J , vol.25 , pp. 39-47
    • Chen, Y.H.1    Chau, L.Y.2    Lin, M.W.3    Chen, L.C.4    Yo, M.H.5    Chen, J.W.6    Lin, S.J.7
  • 54
    • 29644437160 scopus 로고    scopus 로고
    • 4-Hydroxynonenal induces adaptive response and enhances PC12 cell tolerance primarily through induction of thioredoxin reductase 1 via activation of Nrf2
    • Chen ZH, Saito Y, Yoshida Y, Sekine A, Noguchi N, and Niki E. 4-Hydroxynonenal induces adaptive response and enhances PC12 cell tolerance primarily through induction of thioredoxin reductase 1 via activation of Nrf2. J Biol Chem 280: 41921-41927, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 41921-41927
    • Zh, C.1    Saito, Y.2    Yoshida, Y.3    Sekine, A.4    Noguchi, N.5    Niki, E.6
  • 56
    • 0037382541 scopus 로고    scopus 로고
    • Nitric oxide-mediated cytoprotection of hepatocytes from glucose deprivation-induced cytotoxicity: Involvement of heme oxygenase-1
    • Choi BM, Pae HO, Kim YM, and Chung HT. Nitric oxide-mediated cytoprotection of hepatocytes from glucose deprivation-induced cytotoxicity: involvement of heme oxygenase-1. Hepatology 37: 810-823, 2003.
    • (2003) Hepatology , vol.37 , pp. 810-823
    • Choi, B.M.1    Pae, H.O.2    Kim, Y.M.3    Chung, H.T.4
  • 59
    • 0035313488 scopus 로고    scopus 로고
    • FGF and VEGF function in angiogenesis: Signalling pathways, biological responses and therapeutic inhibition
    • Cross MJ and Claesson-Welsh L. FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition. Trends Pharmacol Sci 22: 201-207, 2001.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 201-207
    • Cross, M.J.1    Claesson-Welsh, L.2
  • 61
    • 1642536490 scopus 로고    scopus 로고
    • Innate immune discrimination of apoptotic cells: Repression of proinflammatory macrophage transcription is coupled directly to specific recognition
    • Cvetanovic M and Ucker DS. Innate immune discrimination of apoptotic cells: repression of proinflammatory macrophage transcription is coupled directly to specific recognition. J Immunol 172: 880-889, 2004.
    • (2004) J Immunol , vol.172 , pp. 880-889
    • Cvetanovic, M.1    Ucker, D.S.2
  • 62
    • 34548855958 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 in vivo suppresses NADPH oxidase derived oxidative stress
    • Datla SR, Dusting GJ, Mori TA, Taylor CJ, Croft KD, and Jiang F. Induction of heme oxygenase-1 in vivo suppresses NADPH oxidase derived oxidative stress. Hypertension 50: 636-642, 2007.
    • (2007) Hypertension , vol.50 , pp. 636-642
    • Datla, S.R.1    Dusting, G.J.2    Mori, T.A.3    Taylor, C.J.4    Croft, K.D.5    Jiang, F.6
  • 63
    • 0029159779 scopus 로고
    • Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
    • De Caterina R, Libby P, Peng HB, Thannickal VJ, Rajava-shisth TB, Gimbrone MA Jr., Shin WS, and Liao JK. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Investig 96: 60-68, 1995.
    • (1995) J Clin Investig , vol.96 , pp. 60-68
    • De Caterina, R.1    Libby, P.2    Peng, H.B.3    Thannickal, V.J.4    Rajava-Shisth, T.B.5    Gimbrone Jr., M.A.6    Shin, W.S.7    Liao, J.K.8
  • 65
    • 4644290036 scopus 로고    scopus 로고
    • Probucol protects against smooth muscle cell proliferation by upre-gulating heme oxygenase-1
    • Deng YM, Wu BJ, Witting PK, and Stocker R. Probucol protects against smooth muscle cell proliferation by upre-gulating heme oxygenase-1. Circulation 110: 1855-1860, 2004.
    • (2004) Circulation , vol.110 , pp. 1855-1860
    • Deng, Y.M.1    Wu, B.J.2    Witting, P.K.3    Stocker, R.4
  • 66
    • 14444268977 scopus 로고    scopus 로고
    • Gene transfer of human heme oxygenase-1 into coronary endothelial cells potentially promotes angiogenesis
    • Deramaudt BM, Braunstein S, Remy P, and Abraham NG. Gene transfer of human heme oxygenase-1 into coronary endothelial cells potentially promotes angiogenesis. J Cell Biochem 68: 121-127, 1998.
    • (1998) J Cell Biochem , vol.68 , pp. 121-127
    • Deramaudt, B.M.1    Braunstein, S.2    Remy, P.3    Abraham, N.G.4
  • 68
    • 7944223539 scopus 로고    scopus 로고
    • Vascular repair by circulating endothelial progenitor cells: The missing link in atherosclerosis?
    • Dimmeler S, and Zeiher AM. Vascular repair by circulating endothelial progenitor cells: the missing link in atherosclerosis? J Mol Med 82: 671-677, 2004.
    • (2004) J Mol Med , vol.82 , pp. 671-677
    • Dimmeler, S.1    Zeiher, A.M.2
  • 70
    • 38049132217 scopus 로고    scopus 로고
    • Heme oxygenase-1 and carbon monoxide in vascular pathobi-ology: Focus on angiogenesis
    • Dulak J, Deshane J, Jozkowicz A, and Agarwal A. Heme oxygenase-1 and carbon monoxide in vascular pathobi-ology: focus on angiogenesis. Circulation 117: 231-241, 2008.
    • (2008) Circulation , vol.117 , pp. 231-241
    • Dulak, J.1    Deshane, J.2    Jozkowicz, A.3    Agarwal, A.4
  • 72
    • 53549092236 scopus 로고    scopus 로고
    • Effect of heme oxy-genase-1 on vascular function and disease
    • Dulak J, Loboda A, and Jozkowicz A. Effect of heme oxy-genase-1 on vascular function and disease. Curr Opin Li-pidol 19: 505-512, 2008.
    • (2008) Curr Opin Li-pidol , vol.19 , pp. 505-512
    • Dulak, J.1    Loboda, A.2    Jozkowicz, A.3
  • 73
    • 33845303988 scopus 로고    scopus 로고
    • Role of carbon monoxide in cardiovascular function
    • Durante W, Johnson FK, and Johnson RA. Role of carbon monoxide in cardiovascular function. J Cell Mol Med 10: 672-686, 2006.
    • (2006) J Cell Mol Med , vol.10 , pp. 672-686
    • Durante, W.1    Johnson, F.K.2    Johnson, R.A.3
  • 74
    • 0030961521 scopus 로고    scopus 로고
    • Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells
    • Durante W, Kroll MH, Christodoulides N, Peyton KJ, and Schafer AI. Nitric oxide induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells. Circ Res 80: 557-564, 1997. (Pubitemid 27137293)
    • (1997) Circulation Research , vol.80 , Issue.4 , pp. 557-564
    • Durante, W.1    Kroll, M.H.2    Christodoulides, N.3    Peyton, K.J.4    Schafer, A.I.5
  • 75
    • 0032502738 scopus 로고    scopus 로고
    • Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases
    • Elbirt KK, Whitmarsh AJ, Davis RJ, and Bonkovsky HL. Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases. J Biol Chem 273: 8922-8931, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 8922-8931
    • Elbirt, K.K.1    Whitmarsh, A.J.2    Davis, R.J.3    Bonkovsky, H.L.4
  • 78
    • 0034760290 scopus 로고    scopus 로고
    • Heme oxyge-nase-1 gene promoter microsatellite polymorphism is associated with restenosis after percutaneous transluminal angioplasty
    • Exner M, Schillinger M, Minar E, Mlekusch W, Schlerka G, Haumer M, Mannhalter C, and Wagner O. Heme oxyge-nase-1 gene promoter microsatellite polymorphism is associated with restenosis after percutaneous transluminal angioplasty. J Endovasc Ther 8: 433-440, 2001.
    • (2001) J Endovasc Ther , vol.8 , pp. 433-440
    • Exner, M.1    Schillinger, M.2    Minar, E.3    Mlekusch, W.4    Schlerka, G.5    Haumer, M.6    Mannhalter, C.7    Wagner, O.8
  • 79
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apo-ptotic cells in vitro inhibit proinflammatory cytokine production through autocrine=paracrine mechanisms involving TGF-beta, PGE2, and PAF
    • Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, and Henson PM. Macrophages that have ingested apo-ptotic cells in vitro inhibit proinflammatory cytokine production through autocrine=paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest 101: 890-898, 1998.
    • (1998) J Clin Invest , vol.101 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Henson, P.M.6
  • 80
    • 0038001984 scopus 로고    scopus 로고
    • Vascular endothelial growth factor increases heme oxygenase-1 protein expression in the chick embryo chorioallantoic membrane
    • Fernandez M and Bonkovsky HL. Vascular endothelial growth factor increases heme oxygenase-1 protein expression in the chick embryo chorioallantoic membrane. Br J Pharmacol 139: 634-640, 2003.
    • (2003) Br J Pharmacol , vol.139 , pp. 634-640
    • Fernandez, M.1    Bonkovsky, H.L.2
  • 82
    • 42549163353 scopus 로고    scopus 로고
    • Biliverdin re-ductase: New features of an old enzyme and its potential therapeutic significance
    • Florczyk UM, Jozkowicz A, and Dulak J. Biliverdin re-ductase: new features of an old enzyme and its potential therapeutic significance. Pharmacol Rep 60: 38-48, 2008.
    • (2008) Pharmacol Rep , vol.60 , pp. 38-48
    • Florczyk, U.M.1    Jozkowicz, A.2    Dulak, J.3
  • 83
    • 33748284288 scopus 로고    scopus 로고
    • Heme oxygenase-1 gene transfer inhibits angiotensin II-mediated rat cardiac myocyte apoptosis but not hypertrophy
    • Foo RS, Siow RC, Brown MJ, and Bennett MR. Heme oxygenase-1 gene transfer inhibits angiotensin II-mediated rat cardiac myocyte apoptosis but not hypertrophy. J Cell Physiol 209: 1-7, 2006.
    • (2006) J Cell Physiol , vol.209 , pp. 1-7
    • Foo, R.S.1    Siow, R.C.2    Brown, M.J.3    Bennett, M.R.4
  • 84
    • 0032757252 scopus 로고    scopus 로고
    • The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis
    • Foresti R and Motterlini R. The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis. Free Radic Res 31: 459-475, 1999.
    • (1999) Free Radic Res , vol.31 , pp. 459-475
    • Foresti, R.1    Motterlini, R.2
  • 86
    • 44449162751 scopus 로고    scopus 로고
    • Oxidative stress in vascular disease: Causes, defense mechanisms and potential therapies
    • Fö rstermann U. Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies. Nat Clin Pract Cardiovasc Med 5: 338-349, 2008.
    • (2008) Nat Clin Pract Cardiovasc Med , vol.5 , pp. 338-349
    • Fö Rstermann, U.1
  • 88
    • 33745243736 scopus 로고    scopus 로고
    • Nuclear factor-kappaB-independent anti-inflammatory action of salicylate in human endothelial cells: Induction of heme oxygenase-1 by the c-Jun N-terminal kinase=activator protein-1 pathway
    • Fürst R, Blumenthal SB, Kiemer AK, Zahler S, and Vollmar AM. Nuclear factor-kappaB-independent anti-inflammatory action of salicylate in human endothelial cells: induction of heme oxygenase-1 by the c-Jun N-terminal kinase=activator protein-1 pathway. J Pharmacol Exp Ther 318: 389-394, 2006.
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 389-394
    • Fürst, R.1    Blumenthal, S.B.2    Kiemer, A.K.3    Zahler, S.4    Vollmar, A.M.5
  • 89
    • 11844272574 scopus 로고    scopus 로고
    • Atrial natriuretic peptide induces mitogen-activated protein kinase phosphatase-1 in human endothelial cells via Rac1 and NAD(P)H oxi-dase=Nox2-activation
    • Fürst R, Brueckl C, Kuebler WM, Zahler S, Krötz F, Görlach A, Vollmar AM, and Kiemer AK. Atrial natriuretic peptide induces mitogen-activated protein kinase phosphatase-1 in human endothelial cells via Rac1 and NAD(P)H oxi-dase=Nox2-activation. Circ Res 96: 43-53, 2005.
    • (2005) Circ Res , vol.96 , pp. 43-53
    • Fürst, R.1    Brueckl, C.2    Kuebler, W.M.3    Zahler, S.4    Krötz, F.5    Görlach, A.6    Vollmar, A.M.7    Kiemer, A.K.8
  • 90
    • 67650720510 scopus 로고    scopus 로고
    • Immune and inflammatory mechanisms of atherosclerosis
    • Galkina E and Ley K. Immune and inflammatory mechanisms of atherosclerosis. Annu Rev Immunol 27: 165-197, 2009.
    • (2009) Annu Rev Immunol , vol.27 , pp. 165-197
    • Galkina, E.1    Ley, K.2
  • 93
    • 0037906432 scopus 로고    scopus 로고
    • Distinct role of fibro-blast growth factor-2 and vascular endothelial growth factor on tumor growth and angiogenesis
    • Giavazzi R, Sennino B, Coltrini D, Garofalo A, Dossi R, Ronca R, Tosatti MP, and Presta M. Distinct role of fibro-blast growth factor-2 and vascular endothelial growth factor on tumor growth and angiogenesis. Am J Pathol 162: 1913-1926, 2003.
    • (2003) Am J Pathol , vol.162 , pp. 1913-1926
    • Giavazzi, R.1    Sennino, B.2    Coltrini, D.3    Garofalo, A.4    Dossi, R.5    Ronca, R.6    Tosatti, M.P.7    Presta, M.8
  • 94
    • 0141792612 scopus 로고    scopus 로고
    • Functional expression of human heme oxygenase-1 gene in renal structure of spontaneously hypertensive rats
    • Goodman AI, Quan S, Yang L, Synghal A, and Abraham NG. Functional expression of human heme oxygenase-1 gene in renal structure of spontaneously hypertensive rats. Exp Biol Med (Maywood) 228: 454-458, 2003.
    • (2003) Exp Biol Med (Maywood) , vol.228 , pp. 454-458
    • Goodman, A.I.1    Quan, S.2    Yang, L.3    Synghal, A.4    Abraham, N.G.5
  • 95
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon, S. Alternative activation of macrophages. Nat Rev Immunol 3: 23-35, 2003.
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 103
    • 0021351203 scopus 로고
    • Oxygen toxicity, oxygen radicals, transition metals and disease
    • Halliwell B and Gutteridge JM. Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem J 219: 1-14, 1984.
    • (1984) Biochem J , vol.219 , pp. 1-14
    • Halliwell, B.1    Gutteridge, J.M.2
  • 105
    • 68749092225 scopus 로고    scopus 로고
    • Anti-atherogenic effect of statins: Role of nitric oxide, peroxynitrite and haem oxygenase-1
    • Heeba G, Moselhy ME, Hassan M, Khalifa M, Gryglewski R, and Malinski T. Anti-atherogenic effect of statins: role of nitric oxide, peroxynitrite and haem oxygenase-1., Br J Pharmacol,156, 1256-1266, 2009w
    • (2009) Br J Pharmacol , vol.156 , pp. 1256-1266
    • Heeba, G.1    Moselhy, M.E.2    Hassan, M.3    Khalifa, M.4    Gryglewski, R.5    Malinski, T.6
  • 106
    • 2542464782 scopus 로고    scopus 로고
    • Gene transfer of stromal cell-derived factor-1 enhances ischemic vasculogenesis and angiogenesis via vascular endothelial growth factor=endothelial nitric oxide synthase-related pathway: Next-generation chemokine therapy for therapeutic neovascularization
    • Hiasa K, Ishibashi M, Ohtani K, Inoue S, Zhao Q, Kitamoto S, Sata M, Ichiki T, Takeshita A, and Egashira K. Gene transfer of stromal cell-derived factor-1 enhances ischemic vasculogenesis and angiogenesis via vascular endothelial growth factor=endothelial nitric oxide synthase-related pathway: next-generation chemokine therapy for therapeutic neovascularization. Circulation 109: 2454-2461, 2004.
    • (2004) Circulation , vol.109 , pp. 2454-2461
    • Hiasa, K.1    Ishibashi, M.2    Ohtani, K.3    Inoue, S.4    Zhao, Q.5    Kitamoto, S.6    Sata, M.7    Ichiki, T.8    Takeshita, A.9    Egashira, K.10
  • 108
    • 3242661655 scopus 로고    scopus 로고
    • Heme oxygenase-1 inhibits angiotensin II-induced cardiac hypertrophy in vitro and in vivo
    • Hu CM, Chen YH, Chiang MT, and Chau LY. Heme oxygenase-1 inhibits angiotensin II-induced cardiac hypertrophy in vitro and in vivo. Circulation 110: 309-316, 2004.
    • (2004) Circulation , vol.110 , pp. 309-316
    • Hu, C.M.1    Chen, Y.H.2    Chiang, M.T.3    Chau, L.Y.4
  • 109
    • 0033605676 scopus 로고    scopus 로고
    • Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling
    • Huang LE, Willmore WG, Gu J, Goldberg MA, and Bunn HF. Inhibition of hypoxia-inducible factor 1 activation by carbon monoxide and nitric oxide. Implications for oxygen sensing and signaling. J Biol Chem 274: 9038-9044, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 9038-9044
    • Huang, L.E.1    Willmore, W.G.2    Gu, J.3    Goldberg, M.A.4    Bunn, H.F.5
  • 110
  • 111
    • 33644643191 scopus 로고    scopus 로고
    • The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation
    • Igarashi K and Sun J. The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation. Antioxid Redox Signal 8: 107-118, 2006.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 107-118
    • Igarashi, K.1    Sun, J.2
  • 112
    • 0030930697 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL
    • Ishikawa K, Navab M, Leitinger N, Fogelman AM, and Lusis AJ. Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL. J Clin Invest 100: 1209-1216, 1997.
    • (1997) J Clin Invest , vol.100 , pp. 1209-1216
    • Ishikawa, K.1    Navab, M.2    Leitinger, N.3    Fogelman, A.M.4    Lusis, A.J.5
  • 114
    • 0035896220 scopus 로고    scopus 로고
    • Heme oxygenase-1 inhibits atherosclerotic lesion formation in ldl-receptor knockout mice
    • Ishikawa K, Sugawara D, Wang X, Suzuki K, Itabe H, Maruyama Y, and Lusis AJ. Heme oxygenase-1 inhibits atherosclerotic lesion formation in ldl-receptor knockout mice. Circ Res 88: 506-512, 2001.
    • (2001) Circ Res , vol.88 , pp. 506-512
    • Ishikawa, K.1    Sugawara, D.2    Wang, X.3    Suzuki, K.4    Itabe, H.5    Maruyama, Y.6    Lusis, A.J.7
  • 117
    • 0028814999 scopus 로고
    • A heme oxygenase product, presumably carbon monoxide, mediates a vasodepressor function in rats
    • Johnson RA, Lavesa M, Askari B, Abraham NG, and Nasjletti A. A heme oxygenase product, presumably carbon monoxide, mediates a vasodepressor function in rats. Hypertension 25: 166-169, 1995.
    • (1995) Hypertension , vol.25 , pp. 166-169
    • Johnson, R.A.1    Lavesa, M.2    Askari, B.3    Abraham, N.G.4    Nasjletti, A.5
  • 118
  • 121
    • 1642531778 scopus 로고    scopus 로고
    • Heme oxygenase and angiogenic activity of endothelial cells: Stimulation by carbon monoxide and inhibition by tin protoporphyrin-IX
    • Jozkowicz A, Huk I, Nigisch A, Weigel G, Dietrich W, Motterlini R, and Dulak J. Heme oxygenase and angiogenic activity of endothelial cells: stimulation by carbon monoxide and inhibition by tin protoporphyrin-IX. Antioxid Redox Signal 5: 155-162, 2003.
    • (2003) Antioxid Redox Signal , vol.5 , pp. 155-162
    • Jozkowicz, A.1    Huk, I.2    Nigisch, A.3    Weigel, G.4    Dietrich, W.5    Motterlini, R.6    Dulak, J.7
  • 122
    • 0035949615 scopus 로고    scopus 로고
    • Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice
    • Juan SH, Lee TS, Tseng KW, Liou JY, Shyue SK, Wu KK, and Chau LY. Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice. Circulation 104: 1519-1525, 2001.
    • (2001) Circulation , vol.104 , pp. 1519-1525
    • Juan, S.H.1    Lee, T.S.2    Tseng, K.W.3    Liou, J.Y.4    Shyue, S.K.5    Wu, K.K.6    Chau, L.Y.7
  • 123
    • 0034064581 scopus 로고    scopus 로고
    • Hypoxia differentially regulates stress proteins in cultured cardiomyocytes: Role of the p38 stress-activated kinase signaling cascade, and relation to cytoprotection
    • Kacimi R, Chentoufi J, Honbo N, Long CS, and Karliner JS. Hypoxia differentially regulates stress proteins in cultured cardiomyocytes: role of the p38 stress-activated kinase signaling cascade, and relation to cytoprotection. Cardiovasc Res 46: 139-150, 2000.
    • (2000) Cardiovasc Res , vol.46 , pp. 139-150
    • Kacimi, R.1    Chentoufi, J.2    Honbo, N.3    Long, C.S.4    Karliner, J.S.5
  • 125
    • 61549122310 scopus 로고    scopus 로고
    • Pleiotropic functions of biliverdin reductase: Cellular signaling and generation of cytoprotec-tive and cytotoxic bilirubin
    • Kapitulnik J, Maines MD. Pleiotropic functions of biliverdin reductase: cellular signaling and generation of cytoprotec-tive and cytotoxic bilirubin. Trends Pharmacol Sci 30: 129-137, 2009.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 129-137
    • Kapitulnik, J.1    Maines, M.D.2
  • 126
  • 129
    • 27544494270 scopus 로고    scopus 로고
    • Hemeoxygenase-2 as an O2 sensor in K\+ channel-dependent chemotransduction
    • Kemp PJ. Hemeoxygenase-2 as an O2 sensor in K\+ channel-dependent chemotransduction. Biochem Biophys Res Commun 338: 648-652 2005.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 648-652
    • Kemp, P.J.1
  • 131
    • 23444437384 scopus 로고    scopus 로고
    • Heat shock protein-70 mediates the cyto-protective effect of carbon monoxide: Involvement of p38 beta MAPK and heat shock factor-1
    • Kim HP, Wang X, Zhang J, Suh GY, Benjamin IJ, Ryter SW, and Choi AM. Heat shock protein-70 mediates the cyto-protective effect of carbon monoxide: involvement of p38 beta MAPK and heat shock factor-1. J Immunol 175: 2622-2629, 2005.
    • (2005) J Immunol , vol.175 , pp. 2622-2629
    • Kim, H.P.1    Wang, X.2    Zhang, J.3    Suh, G.Y.4    Benjamin, I.J.5    Ryter, S.W.6    Choi, A.M.7
  • 132
    • 66549126324 scopus 로고    scopus 로고
    • Isoproterenol inhibits angiotensin II-stimulated proliferation and reactive oxygen species production in vascular smooth muscle cells through heme oxygenase-1
    • Kim JE, Kang YJ, Lee KY, and Choi HC. Isoproterenol inhibits angiotensin II-stimulated proliferation and reactive oxygen species production in vascular smooth muscle cells through heme oxygenase-1. Biol Pharm Bull 32: 1047-1052, 2009.
    • (2009) Biol Pharm Bull , vol.32 , pp. 1047-1052
    • Kim, J.E.1    Kang, Y.J.2    Lee, K.Y.3    Choi, H.C.4
  • 133
    • 37349006900 scopus 로고    scopus 로고
    • Carbon monoxide induces heme oxygenase-1 via activation of protein kinase R-like endoplasmic reticulum kinase and inhibits endothelial cell apoptosis triggered by endoplasmic reticulum stress
    • Kim KM, Pae HO, Zheng M, Park R, Kim YM, and Chung HT. Carbon monoxide induces heme oxygenase-1 via activation of protein kinase R-like endoplasmic reticulum kinase and inhibits endothelial cell apoptosis triggered by endoplasmic reticulum stress. Circ Res 101: 919-927, 2007.
    • (2007) Circ Res , vol.101 , pp. 919-927
    • Kim, K.M.1    Pae, H.O.2    Zheng, M.3    Park, R.4    Kim, Y.M.5    Chung, H.T.6
  • 134
    • 0032971430 scopus 로고    scopus 로고
    • Nitric oxide as a bifunctional regulator of apoptosis
    • Kim YM, Bombeck CA, and Billiar TR. Nitric oxide as a bifunctional regulator of apoptosis. Circ Res 84: 253-256, 1999.
    • (1999) Circ Res , vol.84 , pp. 253-256
    • Kim, Y.M.1    Bombeck, C.A.2    Billiar, T.R.3
  • 138
    • 0029814162 scopus 로고    scopus 로고
    • Over-expression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia
    • Lee PJ, Alam J, Wiegand GW, and Choi AM. Over-expression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia. Proc Natl Acad Sci USA 93: 10393-10398, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10393-10398
    • Lee, P.J.1    Alam, J.2    Wiegand, G.W.3    Choi, A.M.4
  • 139
    • 0036127426 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
    • Lee TS and Chau LY. Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat Med 8: 240-246, 2002.
    • (2002) Nat Med , vol.8 , pp. 240-246
    • Lee, T.S.1    Chau, L.Y.2
  • 140
    • 4444369432 scopus 로고    scopus 로고
    • Simvastatin induces heme oxygenase-1: A novel mechanism of vessel protection
    • Lee TS, Chang CC, Zhu Y, and Shyy JY. Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection. Circulation 110: 1296-1302, 2004.
    • (2004) Circulation , vol.110 , pp. 1296-1302
    • Lee, T.S.1    Chang, C.C.2    Zhu, Y.3    Shyy, J.Y.4
  • 141
    • 44349190488 scopus 로고    scopus 로고
    • Human biliverdin reductase is an ERK activator; HBVR is an ERK nuclear transporter and is required for MAPK signaling
    • Lerner-Marmarosh N, Miralem T, Gibbs PE, and Maines MD. Human biliverdin reductase is an ERK activator; hBVR is an ERK nuclear transporter and is required for MAPK signaling. Proc Natl Acad Sci USA 105: 6870-6875, 2008.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 6870-6875
    • Lerner-Marmarosh, N.1    Miralem, T.2    Gibbs, P.E.3    Maines, M.D.4
  • 143
    • 0036392112 scopus 로고    scopus 로고
    • Differential effect of heme oxygenase-1 in endothelial and smooth muscle cell cycle progression
    • Li Volti G, Wang J, Traganos F, Kappas A, and Abraham N. Differential effect of heme oxygenase-1 in endothelial and smooth muscle cell cycle progression. Biochem Biophys Res Commun 296: 1077-1082, 2002.
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 1077-1082
    • Li Volti, G.1    Wang, J.2    Traganos, F.3    Kappas, A.4    Abraham, N.5
  • 145
    • 45549097135 scopus 로고    scopus 로고
    • Heme oxygenase-1 promotes neovascularization in ische-mic heart by coinduction of VEGF and SDF-1
    • Lin HH, Chen YH, Chang PF, Lee YT, Yet SF, and Chau LY. Heme oxygenase-1 promotes neovascularization in ische-mic heart by coinduction of VEGF and SDF-1. J Mol Cell Cardiol 45: 44-55, 2008.
    • (2008) J Mol Cell Cardiol , vol.45 , pp. 44-55
    • Lin, H.H.1    Chen, Y.H.2    Chang, P.F.3    Lee, Y.T.4    Yet, S.F.5    Chau, L.Y.6
  • 146
    • 67949099048 scopus 로고    scopus 로고
    • Heme oxygenase-1=carbon monoxide enhances reendothelialization after vascular injury via promoting mobilization of circulating endothelial progenitor cells
    • Lin HH, Chen YH, Yet SF, and Chau LY. Heme oxygenase-1=carbon monoxide enhances reendothelialization after vascular injury via promoting mobilization of circulating endothelial progenitor cells. J Thromb Haemost 7: 1401-1408, 2009.
    • (2009) J Thromb Haemost , vol.7 , pp. 1401-1408
    • Lin, H.H.1    Chen, Y.H.2    Yet, S.F.3    Chau, L.Y.4
  • 147
    • 0027933447 scopus 로고
    • Heme oxygenase and oxidative stress. Evidence of involvement of bilirubin as physiological protector against oxidative damage
    • Llesuy SF and Tomaro ML. Heme oxygenase and oxidative stress. Evidence of involvement of bilirubin as physiological protector against oxidative damage. Biochim Biophys Acta 1223: 9-14, 1994.
    • (1994) Biochim Biophys Acta , vol.1223 , pp. 9-14
    • Llesuy, S.F.1    Tomaro, M.L.2
  • 149
    • 33744782329 scopus 로고    scopus 로고
    • Atorvastatin prevents hypoxia-induced inhibition of endothelial nitric oxide synthase expression but does not affect heme oxygenase-1 in human micro-vascular endothelial cells
    • Loboda A, Jazwa A, Jozkowicz A, Dorosz J, Balla J, Molema G, and Dulak J. Atorvastatin prevents hypoxia-induced inhibition of endothelial nitric oxide synthase expression but does not affect heme oxygenase-1 in human micro-vascular endothelial cells. Atherosclerosis 187: 26-30, 2006.
    • (2006) Atherosclerosis , vol.187 , pp. 26-30
    • Loboda, A.1    Jazwa, A.2    Jozkowicz, A.3    Dorosz, J.4    Balla, J.5    Molema, G.6    Dulak, J.7
  • 150
    • 2642565248 scopus 로고    scopus 로고
    • Therapeutic angiogenesis and vasculogenesis for ischemic disease: Part I: Angiogenic cytokines
    • DOI 10.1161/01.CIR.0000128595.79378.FA
    • Losordo DW, and Dimmeler S. Therapeutic angiogenesis and vasculogenesis for ischemic disease. Part I: angiogenic cytokines. Circulation 109: 2487-2491, 2004. (Pubitemid 38720544)
    • (2004) Circulation , vol.109 , Issue.21 , pp. 2487-2491
    • Losordo, D.W.1    Dimmeler, S.2
  • 151
    • 34247259885 scopus 로고    scopus 로고
    • Human biliverdin reductase, a previously unknown activator of protein kinase C betaII
    • Maines MD, Miralem T, Lerner-Marmarosh N, Shen J, and Gibbs PE. Human biliverdin reductase, a previously unknown activator of protein kinase C betaII. J Biol Chem 282: 8110-8122, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 8110-8122
    • Maines, M.D.1    Miralem, T.2    Lerner-Marmarosh, N.3    Shen, J.4    Gibbs, P.E.5
  • 152
    • 0030923630 scopus 로고    scopus 로고
    • The heme oxygenase system: A regulator of second messenger gases
    • Maines MD. The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol 37: 517-554, 1997.
    • (1997) Annu Rev Pharmacol Toxicol , vol.37 , pp. 517-554
    • Maines, M.D.1
  • 153
    • 4544312434 scopus 로고    scopus 로고
    • Heme oxygenase and its products in the nervous system
    • Mancuso C. Heme oxygenase and its products in the nervous system. Antioxid Redox Signal 6: 878-887, 2004.
    • (2004) Antioxid Redox Signal , vol.6 , pp. 878-887
    • Mancuso, C.1
  • 154
    • 70450137050 scopus 로고    scopus 로고
    • The heme oxygenase=biliverdin reductase pathway in drug research and development
    • Mancuso C and Barone E. The heme oxygenase=biliverdin reductase pathway in drug research and development. Curr Drug Metab 10: 579-594, 2009.
    • (2009) Curr Drug Metab , vol.10 , pp. 579-594
    • Mancuso, C.1    Barone, E.2
  • 156
    • 0030682163 scopus 로고    scopus 로고
    • Activation of heme oxygenase and consequent carbon monoxide formation inhibits the release of arginine vasopressin from rat hypothalamic explants. Molecular linkage between heme catabolism and neuroendocrine function
    • Mancuso C, Kostoglou-Athanassiou I, Forsling ML, Grossman AB, Preziosi P, Navarra P, and Minotti G. Activation of heme oxygenase and consequent carbon monoxide formation inhibits the release of arginine vasopressin from rat hypothalamic explants. Molecular linkage between heme catabolism and neuroendocrine function. Brain Res Mol Brain Res 50: 267-276 1997.
    • (1997) Brain Res Mol Brain Res , vol.50 , pp. 267-276
    • Mancuso, C.1    Kostoglou-Athanassiou, I.2    Forsling, M.L.3    Grossman, A.B.4    Preziosi, P.5    Navarra, P.6    Minotti, G.7
  • 157
    • 33750978157 scopus 로고    scopus 로고
    • Bilirubin: An endogenous scavenger of nitric oxide and reactive nitrogen species
    • Mancuso C, Pani G, and Calabrese V. Bilirubin: an endogenous scavenger of nitric oxide and reactive nitrogen species. Redox Rep 11: 207-213, 2006.
    • (2006) Redox Rep , vol.11 , pp. 207-213
    • Mancuso, C.1    Pani, G.2    Calabrese, V.3
  • 159
    • 0031148576 scopus 로고    scopus 로고
    • Evidence that carbon monoxide stimulates prostaglandin endoperoxide synthase activity in rat hypo-thalamic explants and in primary cultures of rat hypotha-lamic astrocytes
    • Mancuso C, Pistritto G, Tringali G, Grossman AB, Preziosi P, and Navarra P. Evidence that carbon monoxide stimulates prostaglandin endoperoxide synthase activity in rat hypo-thalamic explants and in primary cultures of rat hypotha-lamic astrocytes. Brain Res Mol Brain Res 45: 294-300, 1997.
    • (1997) Brain Res Mol Brain Res , vol.45 , pp. 294-300
    • Mancuso, C.1    Pistritto, G.2    Tringali, G.3    Grossman, A.B.4    Preziosi, P.5    Navarra, P.6
  • 160
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • Mantovani A, Sozzani S, Locati M, Allavena P, and Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23: 549-555, 2002.
    • (2002) Trends Immunol , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 161
    • 0032431037 scopus 로고    scopus 로고
    • Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors
    • Marti HH and Risau W. Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors. Proc Natl Acad Sci USA 95: 15809-15814, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15809-15814
    • Marti, H.H.1    Risau, W.2
  • 162
    • 8544246393 scopus 로고    scopus 로고
    • Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3
    • McCoubrey WK, Jr., Huang TJ, and Maines MD. Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3. Eur J Biochem 247: 725-732, 1997.
    • (1997) Eur J Biochem , vol.247 , pp. 725-732
    • McCoubrey Jr., W.K.1    Huang, T.J.2    Maines, M.D.3
  • 164
    • 20444445069 scopus 로고    scopus 로고
    • Small interference RNA-mediated gene silencing of human biliverdin reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells
    • Miralem T, Hu Z, Torno MD, Lelli KM, and Maines MD. Small interference RNA-mediated gene silencing of human biliverdin reductase, but not that of heme oxygenase-1, attenuates arsenite-mediated induction of the oxygenase and increases apoptosis in 293A kidney cells. J Biol Chem 280: 17084-17092.
    • J Biol Chem , vol.280 , pp. 17084-17092
    • Miralem, T.1    Hu, Z.2    Torno, M.D.3    Lelli, K.M.4    Maines, M.D.5
  • 167
    • 0028928004 scopus 로고
    • Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP
    • Morita T, Perrella MA, Lee ME, and Kourembanas S. Smooth muscle cell-derived carbon monoxide is a regulator of vascular cGMP. Proc Natl Acad Sci USA 92: 1475-1479, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1475-1479
    • Morita, T.1    Perrella, M.A.2    Lee, M.E.3    Kourembanas, S.4
  • 168
    • 24144476577 scopus 로고    scopus 로고
    • Heme oxygenase and atherosclerosis
    • Morita T. Heme oxygenase and atherosclerosis. Arterioscler Thromb Vasc Biol 25: 1786-1795, 2005.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1786-1795
    • Morita, T.1
  • 169
    • 0036090922 scopus 로고    scopus 로고
    • Carbon monoxide and human disease
    • Morse D and Sethi J. Carbon monoxide and human disease. Antioxid Redox Signal 4: 331-338, 2002.
    • (2002) Antioxid Redox Signal , vol.4 , pp. 331-338
    • Morse, D.1    Sethi, J.2
  • 170
    • 67349252035 scopus 로고    scopus 로고
    • Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease
    • Morse D, Lin L, Choi AM, and Ryter SW. Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease. Free Radic Biol Med 47: 1-12, 2009.
    • (2009) Free Radic Biol Med , vol.47 , pp. 1-12
    • Morse, D.1    Lin, L.2    Choi, A.M.3    Ryter, S.W.4
  • 172
    • 7244253081 scopus 로고    scopus 로고
    • Nrf2-Keap1 defines a physiologically important stress response mechanism
    • Motohashi H and Yamamoto M. Nrf2-Keap1 defines a physiologically important stress response mechanism. Trend Mol Med 10: 549-557, 2004.
    • (2004) Trend Mol Med , vol.10 , pp. 549-557
    • Motohashi, H.1    Yamamoto, M.2
  • 174
    • 0030065052 scopus 로고    scopus 로고
    • NO-mediated activation of heme oxygenase: Endogenous cytoprotection against oxidative stress to endothelium
    • Motterlini R, Foresti R, Intaglietta M, and Winslow RM. NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium. Am J Physiol 270: H107-H114, 1996.
    • (1996) Am J Physiol , vol.270
    • Motterlini, R.1    Foresti, R.2    Intaglietta, M.3    Winslow, R.M.4
  • 176
    • 45749111532 scopus 로고    scopus 로고
    • Application of heme oxygenase-1, carbon monoxide and biliverdin for the prevention of intestinal ischemia=reperfusion injury
    • Nakao A, Kaczorowski DJ, Sugimoto R, Billiar TR, and McCurry KR. Application of heme oxygenase-1, carbon monoxide and biliverdin for the prevention of intestinal ischemia=reperfusion injury. J Clin Biochem Nutr 42: 78-88, 2008.
    • (2008) J Clin Biochem Nutr , vol.42 , pp. 78-88
    • Nakao, A.1    Kaczorowski, D.J.2    Sugimoto, R.3    Billiar, T.R.4    McCurry, K.R.5
  • 179
    • 73549113296 scopus 로고    scopus 로고
    • The heme oxygenase system attenuates pancreatic lesions and improves insulin sensitivity and glucose metabolism in deoxycorticosterone acetate hypertension
    • Ndisang JF and Jadhav A. The heme oxygenase system attenuates pancreatic lesions and improves insulin sensitivity and glucose metabolism in deoxycorticosterone acetate hypertension. Am J Physiol Regul Integr Comp Physiol 298: R211-R223, 2010.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.298
    • Ndisang, J.F.1    Jadhav, A.2
  • 180
    • 66649132533 scopus 로고    scopus 로고
    • Up-regulating the heme oxyge-nase system enhances insulin sensitivity and improves glucose metabolism in insulin-resistant diabetes in Goto-Kakizaki rats
    • Ndisang JF and Jadhav A. Up-regulating the heme oxyge-nase system enhances insulin sensitivity and improves glucose metabolism in insulin-resistant diabetes in Goto-Kakizaki rats. Endocrinology 150: 2627-2636, 2009.
    • (2009) Endocrinology , vol.150 , pp. 2627-2636
    • Ndisang, J.F.1    Jadhav, A.2
  • 181
    • 66449100734 scopus 로고    scopus 로고
    • The heme oxygenase system abates hyperglycemia in Zucker diabetic fatty rats by potentiating insulin-sensitizing pathways
    • Ndisang JF, Lane N, and Jadhav A. The heme oxygenase system abates hyperglycemia in Zucker diabetic fatty rats by potentiating insulin-sensitizing pathways. Endocrinology 150: 2098-2108, 2009.
    • (2009) Endocrinology , vol.150 , pp. 2098-2108
    • Ndisang, J.F.1    Lane, N.2    Jadhav, A.3
  • 182
    • 74949102157 scopus 로고    scopus 로고
    • Up-regulating the heme oxygenase system with hemin improves insulin sensitivity and glucose metabolism in adult spontaneously hypertensive rats
    • Ndisang JF, Lane N, Syed N, and Jadhav A. Up-regulating the heme oxygenase system with hemin improves insulin sensitivity and glucose metabolism in adult spontaneously hypertensive rats. Endocrinology 151: 549-560, 2010.
    • (2010) Endocrinology , vol.151 , pp. 549-560
    • Ndisang, J.F.1    Lane, N.2    Syed, N.3    Jadhav, A.4
  • 183
    • 2642537616 scopus 로고    scopus 로고
    • Carbon monoxide and hypertension
    • Ndisang JF, Tabien HE, and Wang R. Carbon monoxide and hypertension. J Hypertens 22: 1057-1074, 2004.
    • (2004) J Hypertens , vol.22 , pp. 1057-1074
    • Ndisang, J.F.1    Tabien, H.E.2    Wang, R.3
  • 184
    • 0038264420 scopus 로고    scopus 로고
    • Induction of heme oxygenase-1 and stimulation of cGMP production by hemin in aortic tissues from hypertensive rats
    • Ndisang JF, Wu L, Zhao W, and Wang R. Induction of heme oxygenase-1 and stimulation of cGMP production by hemin in aortic tissues from hypertensive rats. Blood 101: 3893-3900, 2003.
    • (2003) Blood , vol.101 , pp. 3893-3900
    • Ndisang, J.F.1    Wu, L.2    Zhao, W.3    Wang, R.4
  • 185
    • 0036711791 scopus 로고    scopus 로고
    • Selective regulation of blood pressure by heme oxygenase-1 in hypertension
    • Ndisang JF, Zhao W, and Wang R. Selective regulation of blood pressure by heme oxygenase-1 in hypertension. Hypertension 40: 315-321, 2002.
    • (2002) Hypertension , vol.40 , pp. 315-321
    • Ndisang, J.F.1    Zhao, W.2    Wang, R.3
  • 186
    • 67649402187 scopus 로고    scopus 로고
    • The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress
    • Nguyen T, Nioi P, and Pickett CB. The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. J Biol Chem 284: 13291-13295, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 13291-13295
    • Nguyen, T.1    Nioi, P.2    Pickett, C.B.3
  • 187
    • 70549084059 scopus 로고    scopus 로고
    • Carbon monoxide (from CORM-2) inhibits high glucose-induced ICAM-1 expression via AMP-activated protein kinase and PPAR-gamma activations in endothelial cells
    • Nizamutdinova IT, Kim YM, Kim HJ, Seo HG, Lee JH, and Chang KC. Carbon monoxide (from CORM-2) inhibits high glucose-induced ICAM-1 expression via AMP-activated protein kinase and PPAR-gamma activations in endothelial cells. Atherosclerosis 207: 405-411, 2009.
    • (2009) Atherosclerosis , vol.207 , pp. 405-411
    • Nizamutdinova, I.T.1    Kim, Y.M.2    Kim, H.J.3    Seo, H.G.4    Lee, J.H.5    Chang, K.C.6
  • 188
    • 23744443462 scopus 로고    scopus 로고
    • HIF-1 activation attenuates postischemic myocar-dial injury: Role for heme oxygenase-1 in modulating mi-crovascular chemokine generation
    • Ockaili, Ramzi, Ramesh Natarajan, Fadi Salloum, Bernard J. Fisher, Drew Jones, Alpha A. Fowler III, and Rakesh C. Kukreja. HIF-1 activation attenuates postischemic myocar-dial injury: role for heme oxygenase-1 in modulating mi-crovascular chemokine generation. Am J Physiol Heart Circ Physiol 289: H542-H548, 2005.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Ramzi, O.1    Natarajan, R.2    Salloum, F.3    Fisher, B.J.4    Jones, D.5    Fowler III, A.A.A.6    Kukreja, R.C.7
  • 189
    • 33745115862 scopus 로고    scopus 로고
    • Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide
    • Oh GS, Pae HO, Lee BS, Kim BN, Kim JM, Kim HR, Jeon SB, Jeon WK, Chae HJ, and Chung HT. Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide. Free Radic Biol Med 41: 106-119, 2006.
    • (2006) Free Radic Biol Med , vol.41 , pp. 106-119
    • Oh, G.S.1    Pae, H.O.2    Lee, B.S.3    Kim, B.N.4    Kim, J.M.5    Kim, H.R.6    Jeon, S.B.7    Jeon, W.K.8    Chae, H.J.9    Chung, H.T.10
  • 190
    • 15844405450 scopus 로고    scopus 로고
    • Effects of genetic ablation of bach1 upon smooth muscle cell proliferation and atherosclerosis after cuff injury
    • Omura S, Suzuki H, Toyofuku M, Ozono R, Kohno N, and Igarashi K. Effects of genetic ablation of bach1 upon smooth muscle cell proliferation and atherosclerosis after cuff injury. Genes Cells 10: 277-285, 2005.
    • (2005) Genes Cells , vol.10 , pp. 277-285
    • Omura, S.1    Suzuki, H.2    Toyofuku, M.3    Ozono, R.4    Kohno, N.5    Igarashi, K.6
  • 191
    • 1842767320 scopus 로고    scopus 로고
    • A promoter variant of the heme oxygenase-1 gene may reduce the incidence of ischemic heart disease in Japanese
    • Ono K, Goto Y, Takagi S, Baba S, Tago N, Nonogi H, and Iwai N. A promoter variant of the heme oxygenase-1 gene may reduce the incidence of ischemic heart disease in Japanese. Atherosclerosis 173: 315-319, 2004.
    • (2004) Atherosclerosis , vol.173 , pp. 315-319
    • Ono, K.1    Goto, Y.2    Takagi, S.3    Baba, S.4    Tago, N.5    Nonogi, H.6    Iwai, N.7
  • 194
  • 197
    • 38349165342 scopus 로고    scopus 로고
    • Costunolide inhibits production of tumor necrosis factor-alpha and interleukin-6 by inducing heme oxygenase-1 in RAW264.7 macrophages
    • Pae HO, Jeong GS, Kim HS, Woo WH, Rhew HY, Kim HS, Sohn DH, Kim YC, and Chung HT. Costunolide inhibits production of tumor necrosis factor-alpha and interleukin-6 by inducing heme oxygenase-1 in RAW264.7 macrophages. Inflamm Res 56: 520-526, 2007.
    • (2007) Inflamm Res , vol.56 , pp. 520-526
    • Pae, H.O.1    Jeong, G.S.2    Kim, H.S.3    Woo, W.H.4    Rhew, H.Y.5    Kim, H.S.6    Sohn, D.H.7    Kim, Y.C.8    Chung, H.T.9
  • 198
    • 46249121630 scopus 로고    scopus 로고
    • Integrative survival response evoked by heme oxygenase-1 and heme metabolites
    • Pae HO, Kim EC, and Chung HT. Integrative survival response evoked by heme oxygenase-1 and heme metabolites. J Clin Biochem Nutr 42: 197-203, 2008.
    • (2008) J Clin Biochem Nutr , vol.42 , pp. 197-203
    • Pae, H.O.1    Kim, E.C.2    Chung, H.T.3
  • 199
    • 61449417240 scopus 로고    scopus 로고
    • Heme oxygenase-1 and carbon monoxide: Emerging therapeutic targets in inflammation and allergy
    • Pae HO, Lee YC, and Chung HT. Heme oxygenase-1 and carbon monoxide: emerging therapeutic targets in inflammation and allergy. Recent Pat Inflamm Allergy Drug Discov 2: 159-165, 2008.
    • (2008) Recent Pat Inflamm Allergy Drug Discov , vol.2 , pp. 159-165
    • Pae, H.O.1    Lee, Y.C.2    Chung, H.T.3
  • 201
    • 17744385995 scopus 로고    scopus 로고
    • A molecular cascade showing nitric oxide-heme oxygenase-1-vascular endothelial growth factor-interleukin-8 sequence in human endothelial cells
    • Pae HO, Oh GS, Choi BM, Kim YM, and Chung HT. A molecular cascade showing nitric oxide-heme oxygenase-1-vascular endothelial growth factor-interleukin-8 sequence in human endothelial cells. Endocrinology 146: 2229-2238, 2005.
    • (2005) Endocrinology , vol.146 , pp. 2229-2238
    • Pae, H.O.1    Oh, G.S.2    Choi, B.M.3    Kim, Y.M.4    Chung, H.T.5
  • 202
    • 33745513491 scopus 로고    scopus 로고
    • 3-Hydroxyanthranilic acid, one of L-tryptophan metabolites, inhibits monocyte chemoattractant protein-1 secretion and vascular cell adhesion molecule-1expression via heme oxygenase-1 induction in human umbilical vein endothelial cells
    • Pae HO, Oh GS, Lee BS, Rim JS, Kim YM, and Chung HT. 3-Hydroxyanthranilic acid, one of L-tryptophan metabolites, inhibits monocyte chemoattractant protein-1 secretion and vascular cell adhesion molecule-1expression via heme oxygenase-1 induction in human umbilical vein endothelial cells. Atherosclerosis 187: 274-284, 2006.
    • (2006) Atherosclerosis , vol.187 , pp. 274-284
    • Pae, H.O.1    Oh, G.S.2    Lee, B.S.3    Rim, J.S.4    Kim, Y.M.5    Chung, H.T.6
  • 203
    • 66749149330 scopus 로고    scopus 로고
    • Molecular mechanisms responsible for the ather-oprotective effects of laminar shear stress
    • Pan S. Molecular mechanisms responsible for the ather-oprotective effects of laminar shear stress. Antioxid Redox Signal 11: 1669-1682, 2009.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 1669-1682
    • Pan, S.1
  • 204
    • 2642597076 scopus 로고    scopus 로고
    • Nitric oxide production contributes to the an-giogenic properties of vascular endothelial growth factor in human endothelial cells
    • Papapetropoulos A, Garcia-Cardena G, Madri JA, and Sessa WC. Nitric oxide production contributes to the an-giogenic properties of vascular endothelial growth factor in human endothelial cells. J Clin Invest 100: 3131-3139, 1997.
    • (1997) J Clin Invest , vol.100 , pp. 3131-3139
    • Papapetropoulos, A.1    Garcia-Cardena, G.2    Madri, J.A.3    Sessa, W.C.4
  • 205
    • 0032693406 scopus 로고    scopus 로고
    • Exhaled carbon monoxide levels elevated in diabetes and correlated with glucose concentration in blood: A new test for monitoring the disease?
    • Paredi P, Biernacki W, Invernizzi G, Kharitonov SA, and Barnes PJ. Exhaled carbon monoxide levels elevated in diabetes and correlated with glucose concentration in blood: a new test for monitoring the disease? Chest 116: 1007-1011, 1999.
    • (1999) Chest , vol.116 , pp. 1007-1011
    • Paredi, P.1    Biernacki, W.2    Invernizzi, G.3    Kharitonov, S.A.4    Barnes, P.J.5
  • 206
    • 67549134935 scopus 로고    scopus 로고
    • Targeting heme oxygenase: Therapeutic implications for diseases of the cardiovascular system
    • Peterson SJ and Frishman WH. Targeting heme oxygenase: therapeutic implications for diseases of the cardiovascular system. Cardiol Rev 17: 99-111, 2009.
    • (2009) Cardiol Rev , vol.17 , pp. 99-111
    • Peterson, S.J.1    Frishman, W.H.2
  • 207
    • 0037097844 scopus 로고    scopus 로고
    • Heme oxygenase-1-derived carbon monoxide is an autocrine inhibitor of vascular smooth muscle cell growth
    • Peyton KJ, Reyna SV, Chapman GB, Ensenat D, Liu XM, Wang H, Schafer AI, and Durante W. Heme oxygenase-1-derived carbon monoxide is an autocrine inhibitor of vascular smooth muscle cell growth. Blood 99: 4443-4448, 2002.
    • (2002) Blood , vol.99 , pp. 4443-4448
    • Peyton, K.J.1    Reyna, S.V.2    Chapman, G.B.3    Ensenat, D.4    Liu, X.M.5    Wang, H.6    Schafer, A.I.7    Durante, W.8
  • 208
    • 0033511832 scopus 로고    scopus 로고
    • Cell biology of heme
    • Ponka P. Cell biology of heme. Am J Med Sci 318: 241-256, 1999.
    • (1999) Am J Med Sci , vol.318 , pp. 241-256
    • Ponka, P.1
  • 209
    • 0030886381 scopus 로고    scopus 로고
    • Heme oxygenase 1 is required for mammalian iron reutilization
    • Poss KD and Tonegawa S. Heme oxygenase 1 is required for mammalian iron reutilization. Proc Natl Acad Sci USA 94: 10919-10924, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10919-10924
    • Poss, K.D.1    Tonegawa, S.2
  • 210
    • 0030886054 scopus 로고    scopus 로고
    • Reduced stress defense in heme oxygenase 1-deficient cells
    • Poss KD and Tonegawa S. Reduced stress defense in heme oxygenase 1-deficient cells. Proc Natl Acad Sci USA 94: 10925-10930, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10925-10930
    • Poss, K.D.1    Tonegawa, S.2
  • 211
    • 0043237804 scopus 로고    scopus 로고
    • Plasma levels of IL-8 predict early complications in patients with coronary heart disease after percutaneous coronary intervention
    • Qi X, Li J, Gu J, Li S, Dang Y, and Wang T. Plasma levels of IL-8 predict early complications in patients with coronary heart disease after percutaneous coronary intervention. Jpn Heart J 44: 451-461, 2003.
    • (2003) Jpn Heart J , vol.44 , pp. 451-461
    • Qi, X.1    Li, J.2    Gu, J.3    Li, S.4    Dang, Y.5    Wang, T.6
  • 212
    • 60949102817 scopus 로고    scopus 로고
    • Hypoxia inducible factor-2: A critical mediator of aggressive tumor phenotypes
    • Qing G and Simon MC. Hypoxia inducible factor-2: a critical mediator of aggressive tumor phenotypes. Curr Opin Genet Dev 19: 60-66, 2009.
    • (2009) Curr Opin Genet Dev , vol.19 , pp. 60-66
    • Qing, G.1    Simon, M.C.2
  • 213
    • 0035834012 scopus 로고    scopus 로고
    • Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs
    • Quan S, Yang L, Abraham NG, and Kappas A. Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs. Proc Natl Acad Sci USA 98: 12203-12208, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12203-12208
    • Quan, S.1    Yang, L.2    Abraham, N.G.3    Kappas, A.4
  • 214
    • 0033009890 scopus 로고    scopus 로고
    • The central effectors of cell death in the immune system
    • Rathmell JC and Thompson CB. The central effectors of cell death in the immune system. Annu Rev Immunol 17: 781-828, 1999.
    • (1999) Annu Rev Immunol , vol.17 , pp. 781-828
    • Rathmell, J.C.1    Thompson, C.B.2
  • 215
    • 33748896774 scopus 로고    scopus 로고
    • Cardiac cell therapy-mixed results from mixed cells
    • Rosenzweig A. Cardiac cell therapy-mixed results from mixed cells. N Engl J Med 355: 1274-1277, 2006.
    • (2006) N Engl J Med , vol.355 , pp. 1274-1277
    • Rosenzweig, A.1
  • 216
    • 34347258918 scopus 로고    scopus 로고
    • Regulatory T cells in health and disease
    • Rouse BT. Regulatory T cells in health and disease. J Intern Med 262: 78-95, 2007.
    • (2007) J Intern Med , vol.262 , pp. 78-95
    • Rouse, B.T.1
  • 217
    • 0035102243 scopus 로고    scopus 로고
    • Reduction of inflammatory response in composite flap transfer by local stress conditioning-induced heat-shock protein 32
    • Rucker M, Schafer T, Roesken F, Spitzer WJ, Bauer M, and Menger MD. Reduction of inflammatory response in composite flap transfer by local stress conditioning-induced heat-shock protein 32. Surgery 129: 292-301, 2001.
    • (2001) Surgery , vol.129 , pp. 292-301
    • Rucker, M.1    Schafer, T.2    Roesken, F.3    Spitzer, W.J.4    Bauer, M.5    Menger, M.D.6
  • 218
    • 33645945014 scopus 로고    scopus 로고
    • Heme oxygenase-1=carbon monoxide: From basic science to therapeutic applications
    • Ryter SW, Alam J, and Choi AM. Heme oxygenase-1=carbon monoxide: from basic science to therapeutic applications. Physiol Rev 86: 583-650, 2006.
    • (2006) Physiol Rev , vol.86 , pp. 583-650
    • Ryter, S.W.1    Alam, J.2    Choi, A.M.3
  • 219
    • 33846914864 scopus 로고    scopus 로고
    • Carbon monoxide and bilirubin: Potential therapies for pulmonary=vascular injury and disease
    • Ryter SW, Morse D, and Choi AM. Carbon monoxide and bilirubin: potential therapies for pulmonary=vascular injury and disease. Am J Respir Cell Mol Biol 36: 175-182, 2007.
    • (2007) Am J Respir Cell Mol Biol , vol.36 , pp. 175-182
    • Ryter, S.W.1    Morse, D.2    Choi, A.M.3
  • 224
    • 0021833801 scopus 로고
    • Characterization of the enzymatic and nonenzymatic peroxidative degradation of iron porphyrins and cytochrome P-450 heme
    • Schaefer WH, Harris TM, and Guengerich FP. Characterization of the enzymatic and nonenzymatic peroxidative degradation of iron porphyrins and cytochrome P-450 heme. Biochemistry 24: 3254-3263, 1985.
    • (1985) Biochemistry , vol.24 , pp. 3254-3263
    • Schaefer, W.H.1    Harris, T.M.2    Guengerich, F.P.3
  • 225
    • 0036633380 scopus 로고    scopus 로고
    • Inducible nitric oxide syn-thase: From cloning to therapeutic applications
    • Schwentker A and Billiar TR. Inducible nitric oxide syn-thase: from cloning to therapeutic applications. World J Surg 26: 772-778, 2002.
    • (2002) World J Surg , vol.26 , pp. 772-778
    • Schwentker, A.1    Billiar, T.R.2
  • 226
    • 77950204203 scopus 로고    scopus 로고
    • Carbon monoxide releasing molecule-2 inhibits pancreatic stellate cell proliferation by activating p38 mitogen-activated protein kinase=heme oxygenase-1 signaling
    • Schwer CI, Mutschler M, Stoll P, Goebel U, Humar M, Hoetzel A, and Schmidt R. Carbon monoxide releasing molecule-2 inhibits pancreatic stellate cell proliferation by activating p38 mitogen-activated protein kinase=heme oxygenase-1 signaling. Mol Pharmacol 77: 660-669, 2010.
    • (2010) Mol Pharmacol , vol.77 , pp. 660-669
    • Schwer, C.I.1    Mutschler, M.2    Stoll, P.3    Goebel, U.4    Humar, M.5    Hoetzel, A.6    Schmidt, R.7
  • 227
    • 38849203158 scopus 로고    scopus 로고
    • Heme oxygenase-1 inhibits the expressionofadhesion molecules associated with endothelial cell activation via inhibition of NF-kB RelA phosphorylation at serine 276
    • Seldon MP, Silva G,PejanovicN,LarsenR,Gregoire IP, Filipe J, Anrather J, and Soares MP. Heme oxygenase-1 inhibits the expressionofadhesion molecules associated with endothelial cell activation via inhibition of NF-kB RelA phosphorylation at serine 276. J Immunol 179: 7840-7851, 2007.
    • (2007) J Immunol , vol.179 , pp. 7840-7851
    • Seldon, M.P.1    Silva, G.2    Pejanovic, N.3    Larsen, R.4    Gregoire, I.P.5    Filipe, J.6    Anrather, J.7    Soares, M.P.8
  • 228
    • 0034921516 scopus 로고    scopus 로고
    • Gene therapy to control hypertension: Current studies and future perspectives
    • Sellers KW, Katovich MJ, Gelband CH, and Raizada MK. Gene therapy to control hypertension: current studies and future perspectives. Am J Med Sci 322: 1-6, 2001.
    • (2001) Am J Med Sci , vol.322 , pp. 1-6
    • Sellers, K.W.1    Katovich, M.J.2    Gelband, C.H.3    Raizada, M.K.4
  • 229
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3: 721-732, 2003.
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 230
    • 33645902493 scopus 로고    scopus 로고
    • Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
    • Serbina NV and Pamer EG. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat Immunol 7: 311-317, 2006.
    • (2006) Nat Immunol , vol.7 , pp. 311-317
    • Serbina, N.V.1    Pamer, E.G.2
  • 232
    • 70450270702 scopus 로고    scopus 로고
    • Diminished upregulation of visceral adipose heme oxygenase-1 correlates with waist-to-hip ratio and insulin resistance
    • Shakeri-Manesch S, Zeyda M, Huber J, Ludvik B, Prager G, and Stulnig TM. Diminished upregulation of visceral adipose heme oxygenase-1 correlates with waist-to-hip ratio and insulin resistance. Int J Obes (Lond) 33: 1257-1264, 2009.
    • (2009) Int J Obes (Lond) , vol.33 , pp. 1257-1264
    • Shakeri-Manesch, S.1    Zeyda, M.2    Huber, J.3    Ludvik, B.4    Prager, G.5    Stulnig, T.M.6
  • 233
    • 0242525192 scopus 로고    scopus 로고
    • The heme oxygenase dilemma in cellular ho-meostasis: New insights for the feedback regulation of heme catabolism
    • Shibahara S. The heme oxygenase dilemma in cellular ho-meostasis: new insights for the feedback regulation of heme catabolism. Tohoku J Exp Med 200: 167-186, 2003.
    • (2003) Tohoku J Exp Med , vol.200 , pp. 167-186
    • Shibahara, S.1
  • 234
    • 43249114710 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-dependent and -independent regulation of angiogenesis
    • Shibuya M. Vascular endothelial growth factor-dependent and -independent regulation of angiogenesis. BMB Rep 41: 278-286, 2008.
    • (2008) BMB Rep , vol.41 , pp. 278-286
    • Shibuya, M.1
  • 240
    • 0036846145 scopus 로고    scopus 로고
    • Carbon monoxide inhibits human airway smooth muscle cell proliferation via mitogen-activated protein kinase pathway
    • Song R, Mahidhara RS, Liu F, Ning W, Otterbein LE, and Choi AM. Carbon monoxide inhibits human airway smooth muscle cell proliferation via mitogen-activated protein kinase pathway. Am J Respir Cell Mol Biol 27: 603-610, 2002.
    • (2002) Am J Respir Cell Mol Biol , vol.27 , pp. 603-610
    • Song, R.1    Mahidhara, R.S.2    Liu, F.3    Ning, W.4    Otterbein, L.E.5    Choi, A.M.6
  • 241
  • 243
    • 29144519820 scopus 로고    scopus 로고
    • CO from enhanced HO activity or from CORM-2 inhibits both O2- and NO production and downregulates HO-1 expression in LPS-stimulated macrophages
    • Srisook K, Han SS, Choi HS, Li MH, Ueda H, Kim C, and Cha YN. CO from enhanced HO activity or from CORM-2 inhibits both O2- and NO production and downregulates HO-1 expression in LPS-stimulated macrophages. Biochem Pharmacol 71: 307-318, 2006.
    • (2006) Biochem Pharmacol , vol.71 , pp. 307-318
    • Srisook, K.1    Han, S.S.2    Choi, H.S.3    Li, M.H.4    Ueda, H.5    Kim, C.6    Cha, Y.N.7
  • 244
    • 40449140745 scopus 로고    scopus 로고
    • Role of carbon monoxide in blood pressure regulation
    • Stec DE, Drummond HA, and Vera T. Role of carbon monoxide in blood pressure regulation. Hypertension 51: 597-604, 2008.
    • (2008) Hypertension , vol.51 , pp. 597-604
    • Stec, D.E.1    Drummond, H.A.2    Vera, T.3
  • 245
    • 4544386856 scopus 로고    scopus 로고
    • Antioxidant activities of bile pigments
    • Stocker R. Antioxidant activities of bile pigments. Antioxid Redox Signal 6: 841-849.
    • Antioxid Redox Signal , vol.6 , pp. 841-849
    • Stocker, R.1
  • 246
    • 33750969074 scopus 로고    scopus 로고
    • Heme oxygenase-1: A novel drug target for atherosclerotic diseases?
    • Stocker R and Perrella MA. Heme oxygenase-1: a novel drug target for atherosclerotic diseases? Circulation 114: 2178-2189, 2006.
    • (2006) Circulation , vol.114 , pp. 2178-2189
    • Stocker, R.1    Perrella, M.A.2
  • 247
    • 0028228808 scopus 로고
    • Soluble guanylate cyclase from bovine lung: Activation with nitric oxide and carbon mon-oxide and spectral characterization of the ferrous and ferric states
    • Stone JR and Marletta MA. Soluble guanylate cyclase from bovine lung: activation with nitric oxide and carbon mon-oxide and spectral characterization of the ferrous and ferric states. Biochemistry, 33, 5636-5640, 1994.
    • (1994) Biochemistry , vol.33 , pp. 5636-5640
    • Stone, J.R.1    Marletta, M.A.2
  • 248
    • 62549154830 scopus 로고    scopus 로고
    • Induction of heme oxygenase 1 by arsenite inhibits cytokine-induced monocyte adhesion to human endothelial cells
    • Sun X, Pi J, Liu W, Hudson LG, Liu KJ, and Feng C. Induction of heme oxygenase 1 by arsenite inhibits cytokine-induced monocyte adhesion to human endothelial cells. Toxicol Appl Pharmacol 236: 202-209, 2009.
    • (2009) Toxicol Appl Pharmacol , vol.236 , pp. 202-209
    • Sun, X.1    Pi, J.2    Liu, W.3    Hudson, L.G.4    Liu, K.J.5    Feng, C.6
  • 251
    • 0018089418 scopus 로고
    • The effects of agents that bind to cytochrome P-450 on hypoxic pulmonary vaso-constriction
    • Sylvester JT and McGowan C. The effects of agents that bind to cytochrome P-450 on hypoxic pulmonary vaso-constriction. Circ Res 43: 429-437, 1978.
    • (1978) Circ Res , vol.43 , pp. 429-437
    • Sylvester, J.T.1    McGowan, C.2
  • 254
    • 21844468521 scopus 로고    scopus 로고
    • Mitochondrial respiratory chain and NAD(P)H oxidase are targets for the antiproliferative effect of carbon monoxide in human airway smooth muscle
    • Taille C, El-Benna J, Lanone S, Boczkowski J, and Motterlini R. Mitochondrial respiratory chain and NAD(P)H oxidase are targets for the antiproliferative effect of carbon monoxide in human airway smooth muscle. J Biol Chem 280: 25350-25360, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 25350-25360
    • Taille, C.1    El-Benna, J.2    Lanone, S.3    Boczkowski, J.4    Motterlini, R.5
  • 257
    • 29344459197 scopus 로고    scopus 로고
    • A vigilant, hypoxia-regulated heme oxygenase-1 gene vector in the heart limits cardiac injury after ischemia-reperfusion in vivo
    • Tang YL, Qian K, Zhang YC, Shen L, and Phillips MI. A vigilant, hypoxia-regulated heme oxygenase-1 gene vector in the heart limits cardiac injury after ischemia-reperfusion in vivo. J Cardiovasc Pharmacol Ther 10: 251-263, 2005.
    • (2005) J Cardiovasc Pharmacol Ther , vol.10 , pp. 251-263
    • Tang, Y.L.1    Qian, K.2    Zhang, Y.C.3    Shen, L.4    Phillips, M.I.5
  • 258
    • 27744505661 scopus 로고    scopus 로고
    • Improved graft mesenchymal stem cell survival in is-chemic heart with a hypoxia-regulated heme oxygenase-1 vector
    • Tang YL, Tang Y, Zhang YC, Qian K, Shen L, and Phillips MI. Improved graft mesenchymal stem cell survival in is-chemic heart with a hypoxia-regulated heme oxygenase-1 vector. J Am Coll Cardiol 46: 1339-1350, 2005.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1339-1350
    • Tang, Y.L.1    Tang, Y.2    Zhang, Y.C.3    Qian, K.4    Shen, L.5    Phillips, M.I.6
  • 259
    • 33645891172 scopus 로고    scopus 로고
    • Cytokines in atherosclerosis: Pathogenic and regulatory pathways
    • Tedgui A and Mallat Z. Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol Rev 86: 515-581, 2006.
    • (2006) Physiol Rev , vol.86 , pp. 515-581
    • Tedgui, A.1    Mallat, Z.2
  • 260
    • 33746665900 scopus 로고    scopus 로고
    • Effect of tumor necrosis factor-alpha and interleukin-1 alpha on heme oxygenase-1 expression in human endothelial cells
    • Terry CM, Clikeman JA, Hoidal JR, and Callahan KS. Effect of tumor necrosis factor-alpha and interleukin-1 alpha on heme oxygenase-1 expression in human endothelial cells. Am J Physiol 274: H883-H891, 1998.
    • (1998) Am J Physiol , vol.274
    • Terry, C.M.1    Clikeman, J.A.2    Hoidal, J.R.3    Callahan, K.S.4
  • 262
    • 0033372937 scopus 로고    scopus 로고
    • Carbon monoxide induces vasodilation and nitric oxide release but suppresses endothelial NOS
    • Thorup C, Jones CL, Gross SS, Moore LC, and Goligorsky MS. Carbon monoxide induces vasodilation and nitric oxide release but suppresses endothelial NOS. Am J Physiol, 277, F882-F889, 1999.
    • (1999) Am J Physiol , vol.277
    • Thorup, C.1    Jones, C.L.2    Gross, S.S.3    Moore, L.C.4    Goligorsky, M.S.5
  • 263
    • 0035179294 scopus 로고    scopus 로고
    • Heme oxygenase-1 protects pancreatic beta cells from apoptosis caused by various stimuli
    • Tobiasch E, Günther L, and Bach FH. Heme oxygenase-1 protects pancreatic beta cells from apoptosis caused by various stimuli. J Invest Med 49: 566-571, 2001.
    • (2001) J Invest Med , vol.49 , pp. 566-571
    • Tobiasch, E.1    Günther, L.2    Bach, F.H.3
  • 265
    • 38349075211 scopus 로고    scopus 로고
    • Anti-inflammatory effects of HO-1 activity in vascular endothelial cells, commentary on "Carbon monoxide donors or heme oxygenase (HO-1) overexpression blocks interleukin-18-mediated NF-kappaB-PTEN-dependent human cardiac endothelial cell death."
    • Tranter M, Jones WK. Anti-inflammatory effects of HO-1 activity in vascular endothelial cells, commentary on "Carbon monoxide donors or heme oxygenase (HO-1) overexpression blocks interleukin-18-mediated NF-kappaB-PTEN-dependent human cardiac endothelial cell death." Free Radic Biol Med 44: 261-263, 2008.
    • (2008) Free Radic Biol Med , vol.44 , pp. 261-263
    • Tranter, M.1    Jones, W.K.2
  • 266
  • 267
    • 0035960644 scopus 로고    scopus 로고
    • Adenovirus-mediated heme oxygenase-1 gene delivery inhibits injury-induced vascular neointima formation
    • Tulis DA, Durante W, Liu X, Evans AJ, Peyton KJ, and Schafer AI. Adenovirus-mediated heme oxygenase-1 gene delivery inhibits injury-induced vascular neointima formation. Circulation 104: 2710-2715, 2001.
    • (2001) Circulation , vol.104 , pp. 2710-2715
    • Tulis, D.A.1    Durante, W.2    Liu, X.3    Evans, A.J.4    Peyton, K.J.5    Schafer, A.I.6
  • 268
    • 0034041022 scopus 로고    scopus 로고
    • Heme oxygenase modulates selectin expression in different regional vascular beds
    • Vachharajani TJ, Work J, Issekutz AC, and Granger DN. Heme oxygenase modulates selectin expression in different regional vascular beds.AmJ Physiol 278: H1613-H1617, 2000.
    • (2000) AmJ Physiol , vol.278
    • Vachharajani, T.J.1    Work, J.2    Issekutz, A.C.3    Granger, D.N.4
  • 269
    • 0032051659 scopus 로고    scopus 로고
    • En-dothelial regrowth after arterial injury: From vascular repair to therapeutics
    • Van Belle E, Bauters C, Asahara T, and Isner JM. En-dothelial regrowth after arterial injury: From vascular repair to therapeutics. Cardiovasc Res 38: 54-68, 1998.
    • (1998) Cardiovasc Res , vol.38 , pp. 54-68
    • Van Belle, E.1    Bauters, C.2    Asahara, T.3    Isner, J.M.4
  • 270
    • 0037448802 scopus 로고    scopus 로고
    • Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: Implications in the antiproliferative response to rapamycin
    • Visner GA, Lu F, Zhou H, Liu J, Kazemfar K, and Agarwal A. Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin. Circulation 107: 911-916, 2003.
    • (2003) Circulation , vol.107 , pp. 911-916
    • Visner, G.A.1    Lu, F.2    Zhou, H.3    Liu, J.4    Kazemfar, K.5    Agarwal, A.6
  • 272
  • 273
    • 0030734872 scopus 로고    scopus 로고
    • Heme induces the expression of adhesion molecules ICAM-1, VCAM-1 and e selectin in vascular endothelial cells
    • Wagener FADTG, Feldman E, Witte de T, and Abraham NG. Heme induces the expression of adhesion molecules ICAM-1, VCAM-1 and E selectin in vascular endothelial cells. Proc Soc Exp Biol Med 216: 456-463, 1997.
    • (1997) Proc Soc Exp Biol Med , vol.216 , pp. 456-463
    • Fadtg, W.1    Feldman, E.2    De T, W.3    Abraham, N.G.4
  • 274
    • 0031935208 scopus 로고    scopus 로고
    • Expression of heme oxygenase-1 in atherosclerotic lesions
    • Wang LJ, Lee TS, Lee FY, Pai RC, and Chau LY. Expression of heme oxygenase-1 in atherosclerotic lesions. Am J Pathol 152: 711-720, 1998.
    • (1998) Am J Pathol , vol.152 , pp. 711-720
    • Wang, L.J.1    Lee, T.S.2    Lee, F.Y.3    Pai, R.C.4    Chau, L.Y.5
  • 275
    • 0030610004 scopus 로고    scopus 로고
    • The chemical modification of K(Ca) channels by carbon monoxide in vascular smooth muscle cells
    • DOI 10.1074/jbc.272.13.8222
    • Wang R and Wu L. The chemical modification of KCa channels by carbon monoxide in vascular smooth muscle cells. J Biol Chem 272: 8222-8226, 1997. (Pubitemid 27147775)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.13 , pp. 8222-8226
    • Wang, R.1    Wu, L.2
  • 276
    • 0005770648 scopus 로고    scopus 로고
    • The direct effect of carbon monoxide on K(Ca) channels in vascular smooth muscle cells
    • DOI 10.1007/s004240050398
    • Wang R, Wu L, and Wang Z. The direct effect of carbon monoxide on KCa channels in vascular smooth muscle cells. Pflugers Arch 434: 285-291, 1997. (Pubitemid 27276232)
    • (1997) Pflugers Archiv European Journal of Physiology , vol.434 , Issue.3 , pp. 285-291
    • Wang, R.1    Wu, L.2    Wang, Z.3
  • 277
    • 33847291917 scopus 로고    scopus 로고
    • Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation
    • Wang X, Wang Y, Kim HP, Nakahira K, Ryter SW, and Choi AM. Carbon monoxide protects against hyperoxia-induced endothelial cell apoptosis by inhibiting reactive oxygen species formation. J Biol Chem 282: 1718-1726, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 1718-1726
    • Wang, X.1    Wang, Y.2    Kim, H.P.3    Nakahira, K.4    Ryter, S.W.5    Choi, A.M.6
  • 278
    • 65449130775 scopus 로고    scopus 로고
    • The heme oxygenase-1=carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1
    • Wang XM, Kim HP, Nakahira K, Ryter SW, and Choi AM. The heme oxygenase-1=carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1. J Immunol 182: 3809-3818, 2009.
    • (2009) J Immunol , vol.182 , pp. 3809-3818
    • Wang, X.M.1    Kim, H.P.2    Nakahira, K.3    Ryter, S.W.4    Choi, A.M.5
  • 280
    • 41349098142 scopus 로고    scopus 로고
    • Endothelial progenitor cells, endothelial dysfunction, inflammation, and oxidative stress in hypertension
    • Watson T, Goon PK, and Lip GY. Endothelial progenitor cells, endothelial dysfunction, inflammation, and oxidative stress in hypertension. Antioxid Redox Signal 10: 1079-1088, 2008.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 1079-1088
    • Watson, T.1    Goon, P.K.2    Lip, G.Y.3
  • 281
    • 65249113865 scopus 로고    scopus 로고
    • Heme oxygenase-1 contributes to an alternative macrophage activation profile induced by apoptotic cell supernatants
    • Weis N, Weigert A, von Knethen A, and Brone B. Heme oxygenase-1 contributes to an alternative macrophage activation profile induced by apoptotic cell supernatants. Mol Biol Cell 20: 1280-1288, 2009.
    • (2009) Mol Biol Cell , vol.20 , pp. 1280-1288
    • Weis, N.1    Weigert, A.2    Von Knethen, A.3    Brone, B.4
  • 282
    • 33645102456 scopus 로고    scopus 로고
    • Evidence for the formation of a novel ni-trosothiol from the gaseous mediators nitric oxide and hydrogen sulphide
    • Whiteman M, Li L, Kostetski I, Chu SH, Siau JL, Bhatia M, and Moore PK. Evidence for the formation of a novel ni-trosothiol from the gaseous mediators nitric oxide and hydrogen sulphide. Biochem Biophys Res Commun 343: 303-310, 2006.
    • (2006) Biochem Biophys Res Commun , vol.343 , pp. 303-310
    • Whiteman, M.1    Li, L.2    Kostetski, I.3    Chu, S.H.4    Siau, J.L.5    Bhatia, M.6    Moore, P.K.7
  • 286
    • 0036196199 scopus 로고    scopus 로고
    • Increased methylglyoxal and oxi-dative stress in hypertensive rat vascular smooth muscle cells
    • Wu L and Juurlink BH. Increased methylglyoxal and oxi-dative stress in hypertensive rat vascular smooth muscle cells. Hypertension 39: 809-814, 2002.
    • (2002) Hypertension , vol.39 , pp. 809-814
    • Wu, L.1    Juurlink, B.H.2
  • 288
    • 0037531136 scopus 로고    scopus 로고
    • Heme oxygenase-1 production by peripheral blood monocytes during acute inflammatory illnesses of children
    • Yachie A, Toma T, Mizuno K, Okamoto H, Shimura S, Ohta K, Kasahara Y, and Koizumi S. Heme oxygenase-1 production by peripheral blood monocytes during acute inflammatory illnesses of children. Exp Biol Med 228: 550-556, 2003.
    • (2003) Exp Biol Med , vol.228 , pp. 550-556
    • Yachie, A.1    Toma, T.2    Mizuno, K.3    Okamoto, H.4    Shimura, S.5    Ohta, K.6    Kasahara, Y.7    Koizumi, S.8
  • 290
    • 0027328231 scopus 로고
    • Induction of stress proteins in mouse peritoneal macrophages by oxidized low-density lipoprotein
    • DOI 10.1006/bbrc.1993.1752
    • Yamaguchi M, Sato H, and Bannai S. Induction of stress proteins in mouse peritoneal macrophages by oxidized low-density lipoprotein. Biochem Biophys Res Commun 193: 1198-1201, 1993. (Pubitemid 23209721)
    • (1993) Biochemical and Biophysical Research Communications , vol.193 , Issue.3 , pp. 1198-1201
    • Yamaguchi, M.1    Sato, H.2    Bannai, S.3
  • 291
    • 0032904795 scopus 로고    scopus 로고
    • Exhaled carbon monoxide levels during treatment of acute asthma
    • Yamaya M, Sekizawa K, Ishizuka S, Monma M, and Sasaki H. Exhaled carbon monoxide levels during treatment of acute asthma. Eur Respir J 13: 757-760, 1999.
    • (1999) Eur Respir J , vol.13 , pp. 757-760
    • Yamaya, M.1    Sekizawa, K.2    Ishizuka, S.3    Monma, M.4    Sasaki, H.5
  • 292
    • 0029855273 scopus 로고    scopus 로고
    • Effect of nitric oxide on heme metabolism in pulmonary artery endothelial cells
    • Yee EL, Pitt BR, Billiar TR, and Kim YM. Effect of nitric oxide on heme metabolism in pulmonary artery endothelial cells. Am J Physiol 271: L512-L518, 1996.
    • (1996) Am J Physiol , vol.271
    • Yee, E.L.1    Pitt, B.R.2    Billiar, T.R.3    Kim, Y.M.4
  • 293
    • 0141706806 scopus 로고    scopus 로고
    • Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodeling
    • Yet SF, Layne MD, Liu X, Chen YH, Ith B, Sibinga NE, and Perrella MA. Absence of heme oxygenase-1 exacerbates atherosclerotic lesion formation and vascular remodeling. FASEB J 17: 1759-1761, 2003.
    • (2003) FASEB J , vol.17 , pp. 1759-1761
    • Yet, S.F.1    Layne, M.D.2    Liu, X.3    Chen, Y.H.4    Ith, B.5    Sibinga, N.E.6    Perrella, M.A.7
  • 295
    • 0035957249 scopus 로고    scopus 로고
    • H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: A study with transgenic mice heterozygous for targeted disruption of the Heme oxygenase-1 gene
    • Yoshida T, Maulik N, Ho YS, Alam J, and Das DK. H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: A study with transgenic mice heterozygous for targeted disruption of the Heme oxygenase-1 gene. Circulation 103: 1695-1701, 2001.
    • (2001) Circulation , vol.103 , pp. 1695-1701
    • Yoshida, T.1    Maulik, N.2    Ho, Y.S.3    Alam, J.4    Das, D.K.5
  • 296
    • 0020479234 scopus 로고
    • A comparative study of heme degradation by NADPH-cytochrome c reductase alone and by the complete heme oxygenase system. Distinctive aspectsofheme degradationbyNADPH-cytochrome c reductase
    • Yoshinaga T, Sassa S, and Kappas A. A comparative study of heme degradation by NADPH-cytochrome c reductase alone and by the complete heme oxygenase system. Distinctive aspectsofheme degradationbyNADPH-cytochrome c reductase. J Biol Chem 257: 7794-7802, 1982.
    • (1982) J Biol Chem , vol.257 , pp. 7794-7802
    • Yoshinaga, T.1    Sassa, S.2    Kappas, A.3
  • 298
    • 20144382493 scopus 로고    scopus 로고
    • Increased heme oxygenase-1 expression in infarcted rat hearts following human bone marrow mesenchymal cell transplantation
    • Zhang S, Lu S, Ge J, Guo J, Chen P, Li T, Zhang P, Jia Z, Ma K, Liu Y, Zhou C, and Li L. Increased heme oxygenase-1 expression in infarcted rat hearts following human bone marrow mesenchymal cell transplantation. Microvasc Res 69: 64-70, 2005.
    • (2005) Microvasc Res , vol.69 , pp. 64-70
    • Zhang, S.1    Lu, S.2    Ge, J.3    Guo, J.4    Chen, P.5    Li, T.6    Zhang, P.7    Jia, Z.8    Ma, K.9    Liu, Y.10    Zhou, C.11    Li, L.12
  • 299
    • 15744378615 scopus 로고    scopus 로고
    • Carbon monoxide differentially modulates STAT1 and STAT3 and inhibits apoptosis via a phosphatidylinositol 3-kinase=Akt and p38 kinase-dependent STAT3 pathway during anoxia-reoxygenation injury
    • Zhang X, Shan P, Alam J, Fu XY, and Lee PJ. Carbon monoxide differentially modulates STAT1 and STAT3 and inhibits apoptosis via a phosphatidylinositol 3-kinase=Akt and p38 kinase-dependent STAT3 pathway during anoxia-reoxygenation injury. J Biol Chem 280: 8714-9721, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 8714-9721
    • Zhang, X.1    Shan, P.2    Alam, J.3    Fu, X.Y.4    Lee, P.J.5
  • 300
    • 33947628672 scopus 로고    scopus 로고
    • Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mi-tochondrial reactive oxygen species
    • Zuckerbraun BS, Chin BY, Bilban M, d'Avila JC, Rao J, Billiar TR, and Otterbein LE. Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mi-tochondrial reactive oxygen species. FASEB J 21: 1099-1106, 2007.
    • (2007) FASEB J , vol.21 , pp. 1099-1106
    • Zuckerbraun, B.S.1    Chin, B.Y.2    Bilban, M.3    D'Avila, J.C.4    Rao, J.5    Billiar, T.R.6    Otterbein, L.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.