-
1
-
-
77950324131
-
Murine schistosomiasis as a model for human schistosomiasis mansoni: Similarities and discrepancies
-
Abdul-Ghani RA, Hassan AA. Murine schistosomiasis as a model for human schistosomiasis mansoni: similarities and discrepancies. Parasitol Res 107: 1-8, 2010.
-
(2010)
Parasitol Res
, vol.107
, pp. 1-8
-
-
Abdul-Ghani, R.A.1
Hassan, A.A.2
-
2
-
-
78751541079
-
Fructose at the center of necroinflammation and fibrosis in nonalcoholic steatohepatitis
-
Alisi A, Manco M, Pezzullo M, Nobili V. Fructose at the center of necroinflammation and fibrosis in nonalcoholic steatohepatitis. Hepatology 53: 372-373, 2010.
-
(2010)
Hepatology
, vol.53
, pp. 372-373
-
-
Alisi, A.1
Manco, M.2
Pezzullo, M.3
Nobili, V.4
-
3
-
-
33644955272
-
Mouse models in non-alcoholic fatty liver disease and steatohepatitis research
-
Anstee QM, Goldin RD. Mouse models in non-alcoholic fatty liver disease and steatohepatitis research. Int J Exp Pathol 87: 1-16, 2006.
-
(2006)
Int J Exp Pathol
, vol.87
, pp. 1-16
-
-
Anstee, Q.M.1
Goldin, R.D.2
-
4
-
-
33644897826
-
Adaptive failure to high-fat diet characterizes steatohepatitis in Alms1 mutant mice
-
Arsov T, Larter CZ, Nolan CJ, Petrovsky N, Goodnow CC, Teoh NC, Yeh MM, Farrell GC. Adaptive failure to high-fat diet characterizes steatohepatitis in Alms1 mutant mice. Biochem Biophys Res Commun 342: 1152-1159, 2006.
-
(2006)
Biochem Biophys Res Commun
, vol.342
, pp. 1152-1159
-
-
Arsov, T.1
Larter, C.Z.2
Nolan, C.J.3
Petrovsky, N.4
Goodnow, C.C.5
Teoh, N.C.6
Yeh, M.M.7
Farrell, G.C.8
-
5
-
-
34547730702
-
-/- mice
-
-/- mice. Nat Biotechnol 25: 903-910, 2007.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 903-910
-
-
Azuma, H.1
Paulk, N.2
Ranade, A.3
Dorrell, C.4
Al-Dhalimy, M.5
Ellis, E.6
Strom, S.7
Kay, M.A.8
Finegold, M.9
Grompe, M.10
-
6
-
-
31844448804
-
Development of nonhuman adenoviruses as vaccine vectors
-
Bangari DS, Mittal SK. Development of nonhuman adenoviruses as vaccine vectors. Vaccine 24: 849-862, 2006.
-
(2006)
Vaccine
, vol.24
, pp. 849-862
-
-
Bangari, D.S.1
Mittal, S.K.2
-
8
-
-
44649093803
-
Mouse models for the study of HCV infection and virus-host interactions
-
Barth H, Robinet E, Liang TJ, Baumert TF. Mouse models for the study of HCV infection and virus-host interactions. J Hepatol 49: 134-142, 2008.
-
(2008)
J Hepatol
, vol.49
, pp. 134-142
-
-
Barth, H.1
Robinet, E.2
Liang, T.J.3
Baumert, T.F.4
-
9
-
-
0031925283
-
Analysis of hepatitis C virusinoculated chimpanzees reveals unexpected clinical profiles
-
Bassett SE, Brasky KM, Lanford RE. Analysis of hepatitis C virusinoculated chimpanzees reveals unexpected clinical profiles. J Virol 72: 2589-2599, 1998.
-
(1998)
J Virol
, vol.72
, pp. 2589-2599
-
-
Bassett, S.E.1
Brasky, K.M.2
Lanford, R.E.3
-
10
-
-
0032532306
-
Human class I supertypes and CTL repertoires extend to chimpanzees
-
Bertoni R, Sette A, Sidney J, Guidotti LG, Shapiro M, Purcell R, Chisari FV. Human class I supertypes and CTL repertoires extend to chimpanzees. J Immunol 161: 4447-4455, 1998.
-
(1998)
J Immunol
, vol.161
, pp. 4447-4455
-
-
Bertoni, R.1
Sette, A.2
Sidney, J.3
Guidotti, L.G.4
Shapiro, M.5
Purcell, R.6
Chisari, F.V.7
-
11
-
-
84856297712
-
LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease
-
Bieghs V, Van Gorp PJ, Wouters K, Hendrikx T, Gijbels MJ, van Bilsen M, Bakker J, Binder CJ, Lutjohann D, Staels B, Hofker MH, Shiri-Sverdlov R. LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease. PLoS ONE 7: e30668, 2012.
-
(2012)
PLoS ONE
, vol.7
-
-
Bieghs, V.1
van Gorp, P.J.2
Wouters, K.3
Hendrikx, T.4
Gijbels, M.J.5
van Bilsen, M.6
Bakker, J.7
Binder, C.J.8
Lutjohann, D.9
Staels, B.10
Hofker, M.H.11
Shiri-Sverdlov, R.12
-
12
-
-
80052548485
-
Therapy for hepatic fibrosis: Revisiting the preclinical models
-
Bissell DM. Therapy for hepatic fibrosis: revisiting the preclinical models. Clin Res Hepatol Gastroenterol 35: 521-525, 2011.
-
(2011)
Clin Res Hepatol Gastroenterol
, vol.35
, pp. 521-525
-
-
Bissell, D.M.1
-
13
-
-
38049164210
-
Repopulation of adult and neonatal mice with human hepatocytes: A chimeric animal model
-
Bissig KD, Le TT, Woods NB, Verma IM. Repopulation of adult and neonatal mice with human hepatocytes: a chimeric animal model. Proc Natl Acad Sci USA 104: 20507-20511, 2007.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20507-20511
-
-
Bissig, K.D.1
Le, T.T.2
Woods, N.B.3
Verma, I.M.4
-
14
-
-
77949725830
-
Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment
-
Bissig KD, Wieland SF, Tran P, Isogawa M, Le TT, Chisari FV, Verma IM. Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment. J Clin Invest 120: 924-930, 2010.
-
(2010)
J Clin Invest
, vol.120
, pp. 924-930
-
-
Bissig, K.D.1
Wieland, S.F.2
Tran, P.3
Isogawa, M.4
Le, T.T.5
Chisari, F.V.6
Verma, I.M.7
-
15
-
-
72949089500
-
Experimental models for hepatitis C viral infection
-
Boonstra A, van der Laan LJ, Vanwolleghem T, Janssen HL. Experimental models for hepatitis C viral infection. Hepatology 50: 1646-1655, 2009.
-
(2009)
Hepatology
, vol.50
, pp. 1646-1655
-
-
Boonstra, A.1
van der Laan, L.J.2
Vanwolleghem, T.3
Janssen, H.L.4
-
16
-
-
0024400632
-
Immunopathology of Schistosoma mansoni infection
-
Boros DL. Immunopathology of Schistosoma mansoni infection. Clin Microbiol Rev 2: 250-269, 1989.
-
(1989)
Clin Microbiol Rev
, vol.2
, pp. 250-269
-
-
Boros, D.L.1
-
17
-
-
0023730861
-
Synergism between ethanol and carbon tetrachloride in the generation of liver fibrosis
-
Bosma A, Brouwer A, Seifert WF, Knook DL. Synergism between ethanol and carbon tetrachloride in the generation of liver fibrosis. J Pathol 156: 15-21, 1988.
-
(1988)
J Pathol
, vol.156
, pp. 15-21
-
-
Bosma, A.1
Brouwer, A.2
Seifert, W.F.3
Knook, D.L.4
-
18
-
-
0033200054
-
Nonalcoholic steatohepatitis: A proposal for grading and staging the histological lesions
-
Brunt EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol 94: 2467-2474, 1999.
-
(1999)
Am J Gastroenterol
, vol.94
, pp. 2467-2474
-
-
Brunt, E.M.1
Janney, C.G.2
Di Bisceglie, A.M.3
Neuschwander-Tetri, B.A.4
Bacon, B.R.5
-
19
-
-
20044385758
-
Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma
-
Campbell JS, Hughes SD, Gilbertson DG, Palmer TE, Holdren MS, Haran AC, Odell MM, Bauer RL, Ren HP, Haugen HS, Yeh MM, Fausto N. Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma. Proc Natl Acad Sci USA 102: 3389-3394, 2005.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 3389-3394
-
-
Campbell, J.S.1
Hughes, S.D.2
Gilbertson, D.G.3
Palmer, T.E.4
Holdren, M.S.5
Haran, A.C.6
Odell, M.M.7
Bauer, R.L.8
Ren, H.P.9
Haugen, H.S.10
Yeh, M.M.11
Fausto, N.12
-
20
-
-
11244348954
-
A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats
-
Carmiel-Haggai M, Cederbaum AI, Nieto N. A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats. FASEB J 19: 136-138, 2005.
-
(2005)
FASEB J
, vol.19
, pp. 136-138
-
-
Carmiel-Haggai, M.1
Cederbaum, A.I.2
Nieto, N.3
-
21
-
-
0022551673
-
Acetone potentiation of chronic liver injury induced by repetitive administration of carbon tetrachloride
-
Charbonneau M, Tuchweber B, Plaa GL. Acetone potentiation of chronic liver injury induced by repetitive administration of carbon tetrachloride. Hepatology 6: 694-700, 1986.
-
(1986)
Hepatology
, vol.6
, pp. 694-700
-
-
Charbonneau, M.1
Tuchweber, B.2
Plaa, G.L.3
-
22
-
-
80055026523
-
Fast food diet mouse: Novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition
-
Charlton M, Krishnan A, Viker K, Sanderson S, Cazanave S, Mc-Conico A, Masuoko H, Gores G. Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition. Am J Physiol Gastrointest Liver Physiol 301: G825-G834, 2011.
-
(2011)
Am J Physiol Gastrointest Liver Physiol
, vol.301
-
-
Charlton, M.1
Krishnan, A.2
Viker, K.3
Sanderson, S.4
Cazanave, S.5
Mc-Conico, A.6
Masuoko, H.7
Gores, G.8
-
23
-
-
80052178313
-
Conditional gene expression in hepatitis C virus transgenic mice without induction of severe liver injury using a non-inflammatory Cre-expressing adenovirus
-
Chiyo T, Sekiguchi S, Hayashi M, Tobita Y, Kanegae Y, Saito I, Kohara M. Conditional gene expression in hepatitis C virus transgenic mice without induction of severe liver injury using a non-inflammatory Cre-expressing adenovirus. Virus Res 160: 89-97, 2011.
-
(2011)
Virus Res
, vol.160
, pp. 89-97
-
-
Chiyo, T.1
Sekiguchi, S.2
Hayashi, M.3
Tobita, Y.4
Kanegae, Y.5
Saito, I.6
Kohara, M.7
-
25
-
-
1242270574
-
Induction, acceleration or prevention of autoimmunity by molecular mimicry
-
Christen U, von Herrath MG. Induction, acceleration or prevention of autoimmunity by molecular mimicry. Mol Immunol 40: 1113-1120, 2004.
-
(2004)
Mol Immunol
, vol.40
, pp. 1113-1120
-
-
Christen, U.1
von Herrath, M.G.2
-
28
-
-
33746561298
-
Liver fibrosis induced by hepatic overexpression of PDGF-B in transgenic mice
-
Czochra P, Klopcic B, Meyer E, Herkel J, Garcia-Lazaro JF, Thieringer F, Schirmacher P, Biesterfeld S, Galle PR, Lohse AW, Kanzler S. Liver fibrosis induced by hepatic overexpression of PDGF-B in transgenic mice. J Hepatol 45: 419-428, 2006.
-
(2006)
J Hepatol
, vol.45
, pp. 419-428
-
-
Czochra, P.1
Klopcic, B.2
Meyer, E.3
Herkel, J.4
Garcia-Lazaro, J.F.5
Thieringer, F.6
Schirmacher, P.7
Biesterfeld, S.8
Galle, P.R.9
Lohse, A.W.10
Kanzler, S.11
-
29
-
-
17744378552
-
Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus
-
Dandri M, Burda MR, Torok E, Pollok JM, Iwanska A, Sommer G, Rogiers X, Rogler CE, Gupta S, Will H, Greten H, Petersen J. Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus. Hepatology 33: 981-988, 2001.
-
(2001)
Hepatology
, vol.33
, pp. 981-988
-
-
Dandri, M.1
Burda, M.R.2
Torok, E.3
Pollok, J.M.4
Iwanska, A.5
Sommer, G.6
Rogiers, X.7
Rogler, C.E.8
Gupta, S.9
Will, H.10
Greten, H.11
Petersen, J.12
-
30
-
-
19944421720
-
Chronic infection with hepatitis B viruses and antiviral drug evaluation in uPA mice after liver repopulation with tupaia hepatocytes
-
Dandri M, Burda MR, Zuckerman DM, Wursthorn K, Matschl U, Pollok JM, Rogiers X, Gocht A, Kock J, Blum HE, von Weizsacker F, Petersen J. Chronic infection with hepatitis B viruses and antiviral drug evaluation in uPA mice after liver repopulation with tupaia hepatocytes. J Hepatol 42: 54-60, 2005.
-
(2005)
J Hepatol
, vol.42
, pp. 54-60
-
-
Dandri, M.1
Burda, M.R.2
Zuckerman, D.M.3
Wursthorn, K.4
Matschl, U.5
Pollok, J.M.6
Rogiers, X.7
Gocht, A.8
Kock, J.9
Blum, H.E.10
von Weizsacker, F.11
Petersen, J.12
-
31
-
-
33646339646
-
Small animal model systems for studying hepatitis B virus replication and pathogenesis
-
Dandri M, Lutgehetmann M, Volz T, Petersen J. Small animal model systems for studying hepatitis B virus replication and pathogenesis. Semin Liver Dis 26: 181-191, 2006.
-
(2006)
Semin Liver Dis
, vol.26
, pp. 181-191
-
-
Dandri, M.1
Lutgehetmann, M.2
Volz, T.3
Petersen, J.4
-
32
-
-
32044433759
-
Animal models for the study of HBV replication and its variants
-
Dandri M, Volz TK, Lutgehetmann M, Petersen J. Animal models for the study of HBV replication and its variants. J Clin Virol 34, Suppl 1: S54-S62, 2005.
-
(2005)
J Clin Virol
, vol.34
, Issue.SUPPL. 1
-
-
Dandri, M.1
Volz, T.K.2
Lutgehetmann, M.3
Petersen, J.4
-
33
-
-
25844456719
-
Steatohepatitis induced by intragastric overfeeding in mice
-
Deng QG, She H, Cheng JH, French SW, Koop DR, Xiong S, Tsukamoto H. Steatohepatitis induced by intragastric overfeeding in mice. Hepatology 42: 905-914, 2005.
-
(2005)
Hepatology
, vol.42
, pp. 905-914
-
-
Deng, Q.G.1
She, H.2
Cheng, J.H.3
French, S.W.4
Koop, D.R.5
Xiong, S.6
Tsukamoto, H.7
-
34
-
-
0033391153
-
Concanavalin A-induced hepatitis in mice is prevented by interleukin (IL)-10 and exacerbated by endogenous IL-10 deficiency
-
Di Marco R, Xiang M, Zaccone P, Leonardi C, Franco S, Meroni P, Nicoletti F. Concanavalin A-induced hepatitis in mice is prevented by interleukin (IL)-10 and exacerbated by endogenous IL-10 deficiency. Autoimmunity 31: 75-83, 1999.
-
(1999)
Autoimmunity
, vol.31
, pp. 75-83
-
-
Di Marco, R.1
Xiang, M.2
Zaccone, P.3
Leonardi, C.4
Franco, S.5
Meroni, P.6
Nicoletti, F.7
-
35
-
-
71549163153
-
A novel model of CCl4-induced cirrhosis with ascites in the mouse
-
Domenicali M, Caraceni P, Giannone F, Baldassarre M, Lucchetti G, Quarta C, Patti C, Catani L, Nanni C, Lemoli RM, Bernardi M. A novel model of CCl4-induced cirrhosis with ascites in the mouse. J Hepatol 51: 991-999, 2009.
-
(2009)
J Hepatol
, vol.51
, pp. 991-999
-
-
Domenicali, M.1
Caraceni, P.2
Giannone, F.3
Baldassarre, M.4
Lucchetti, G.5
Quarta, C.6
Patti, C.7
Catani, L.8
Nanni, C.9
Lemoli, R.M.10
Bernardi, M.11
-
36
-
-
77956024846
-
Expression of fatty acid synthase in nonalcoholic fatty liver disease
-
Dorn C, Riener MO, Kirovski G, Saugspier M, Steib K, Weiss TS, Gabele E, Kristiansen G, Hartmann A, Hellerbrand C. Expression of fatty acid synthase in nonalcoholic fatty liver disease. Int J Clin Exp Pathol 3: 505-514, 2010.
-
(2010)
Int J Clin Exp Pathol
, vol.3
, pp. 505-514
-
-
Dorn, C.1
Riener, M.O.2
Kirovski, G.3
Saugspier, M.4
Steib, K.5
Weiss, T.S.6
Gabele, E.7
Kristiansen, G.8
Hartmann, A.9
Hellerbrand, C.10
-
37
-
-
79958291149
-
A genetically humanized mouse model for hepatitis C virus infection
-
Dorner M, Horwitz JA, Robbins JB, Barry WT, Feng Q, Mu K, Jones CT, Schoggins JW, Catanese MT, Burton DR, Law M, Rice CM, Ploss A. A genetically humanized mouse model for hepatitis C virus infection. Nature 474: 208-211, 2011.
-
(2011)
Nature
, vol.474
, pp. 208-211
-
-
Dorner, M.1
Horwitz, J.A.2
Robbins, J.B.3
Barry, W.T.4
Feng, Q.5
Mu, K.6
Jones, C.T.7
Schoggins, J.W.8
Catanese, M.T.9
Burton, D.R.10
Law, M.11
Rice, C.M.12
Ploss, A.13
-
38
-
-
80052584948
-
Autoimmune liver disease-are there spectra that we do not know?
-
Fallatah HI, Akbar HO. Autoimmune liver disease-are there spectra that we do not know? Comp Hepatol 10: 9, 2011.
-
(2011)
Comp Hepatol
, vol.10
, pp. 9
-
-
Fallatah, H.I.1
Akbar, H.O.2
-
39
-
-
67549113925
-
Commonly used animal models of non-alcoholic steatohepatitis
-
Fan JG, Qiao L. Commonly used animal models of non-alcoholic steatohepatitis. Hepatobiliary Pancreat Dis Int 8: 233-240, 2009.
-
(2009)
Hepatobiliary Pancreat Dis Int
, vol.8
, pp. 233-240
-
-
Fan, J.G.1
Qiao, L.2
-
40
-
-
33644547706
-
Nonalcoholic fatty liver disease: From steatosis to cirrhosis
-
Farrell GC, Larter CZ. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 43: S99-S112, 2006.
-
(2006)
Hepatology
, vol.43
-
-
Farrell, G.C.1
Larter, C.Z.2
-
41
-
-
3242727039
-
Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice
-
Fickert P, Fuchsbichler A, Wagner M, Zollner G, Kaser A, Tilg H, Krause R, Lammert F, Langner C, Zatloukal K, Marschall HU, Denk H, Trauner M. Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology 127: 261-274, 2004.
-
(2004)
Gastroenterology
, vol.127
, pp. 261-274
-
-
Fickert, P.1
Fuchsbichler, A.2
Wagner, M.3
Zollner, G.4
Kaser, A.5
Tilg, H.6
Krause, R.7
Lammert, F.8
Langner, C.9
Zatloukal, K.10
Marschall, H.U.11
Denk, H.12
Trauner, M.13
-
42
-
-
34548308940
-
A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis
-
Fickert P, Stoger U, Fuchsbichler A, Moustafa T, Marschall HU, Weiglein AH, Tsybrovskyy O, Jaeschke H, Zatloukal K, Denk H, Trauner M. A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis. Am J Pathol 171: 525-536, 2007.
-
(2007)
Am J Pathol
, vol.171
, pp. 525-536
-
-
Fickert, P.1
Stoger, U.2
Fuchsbichler, A.3
Moustafa, T.4
Marschall, H.U.5
Weiglein, A.H.6
Tsybrovskyy, O.7
Jaeschke, H.8
Zatloukal, K.9
Denk, H.10
Trauner, M.11
-
43
-
-
77954568757
-
The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobioticinduced cholangitis and biliary fibrosis in mice
-
Fickert P, Thueringer A, Moustafa T, Silbert D, Gumhold J, Tsybrovskyy O, Lebofsky M, Jaeschke H, Denk H, Trauner M. The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobioticinduced cholangitis and biliary fibrosis in mice. Lab Invest 90: 844-852, 2010.
-
(2010)
Lab Invest
, vol.90
, pp. 844-852
-
-
Fickert, P.1
Thueringer, A.2
Moustafa, T.3
Silbert, D.4
Gumhold, J.5
Tsybrovskyy, O.6
Lebofsky, M.7
Jaeschke, H.8
Denk, H.9
Trauner, M.10
-
44
-
-
0036900927
-
Bile acid-induced Mallory body formation in drug-primed mouse liver
-
Fickert P, Trauner M, Fuchsbichler A, Stumptner C, Zatloukal K, Denk H. Bile acid-induced Mallory body formation in drug-primed mouse liver. Am J Pathol 161: 2019-2026, 2002.
-
(2002)
Am J Pathol
, vol.161
, pp. 2019-2026
-
-
Fickert, P.1
Trauner, M.2
Fuchsbichler, A.3
Stumptner, C.4
Zatloukal, K.5
Denk, H.6
-
45
-
-
32044467118
-
24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice
-
Fickert P, Wagner M, Marschall HU, Fuchsbichler A, Zollner G, Tsybrovskyy O, Zatloukal K, Liu J, Waalkes MP, Cover C, Denk H, Hofmann AF, Jaeschke H, Trauner M. 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology 130: 465-481, 2006.
-
(2006)
Gastroenterology
, vol.130
, pp. 465-481
-
-
Fickert, P.1
Wagner, M.2
Marschall, H.U.3
Fuchsbichler, A.4
Zollner, G.5
Tsybrovskyy, O.6
Zatloukal, K.7
Liu, J.8
Waalkes, M.P.9
Cover, C.10
Denk, H.11
Hofmann, A.F.12
Jaeschke, H.13
Trauner, M.14
-
46
-
-
0036788262
-
Ursodeoxycholic acid aggravates bile infarcts in bile ductligated and Mdr2 knockout mice via disruption of cholangioles
-
Fickert P, Zollner G, Fuchsbichler A, Stumptner C, Weiglein AH, Lammert F, Marschall HU, Tsybrovskyy O, Zatloukal K, Denk H, Trauner M. Ursodeoxycholic acid aggravates bile infarcts in bile ductligated and Mdr2 knockout mice via disruption of cholangioles. Gastroenterology 123: 1238-1251, 2002.
-
(2002)
Gastroenterology
, vol.123
, pp. 1238-1251
-
-
Fickert, P.1
Zollner, G.2
Fuchsbichler, A.3
Stumptner, C.4
Weiglein, A.H.5
Lammert, F.6
Marschall, H.U.7
Tsybrovskyy, O.8
Zatloukal, K.9
Denk, H.10
Trauner, M.11
-
47
-
-
0035049639
-
Pro-and anti-inflammatory gene expression in the murine small intestine and liver after chronic exposure to alcohol
-
Fleming S, Toratani S, Shea-Donohue T, Kashiwabara Y, Vogel SN, Metcalf ES. Pro-and anti-inflammatory gene expression in the murine small intestine and liver after chronic exposure to alcohol. Alcohol Clin Exp Res 25: 579-589, 2001.
-
(2001)
Alcohol Clin Exp Res
, vol.25
, pp. 579-589
-
-
Fleming, S.1
Toratani, S.2
Shea-Donohue, T.3
Kashiwabara, Y.4
Vogel, S.N.5
Metcalf, E.S.6
-
48
-
-
0022830407
-
Ethanol-induced hepatic fibrosis in the rat: Role of the amount of dietary fat
-
French SW, Miyamoto K, Tsukamoto H. Ethanol-induced hepatic fibrosis in the rat: role of the amount of dietary fat. Alcohol Clin Exp Res 10: 13S-19S, 1986.
-
(1986)
Alcohol Clin Exp Res
, vol.10
-
-
French, S.W.1
Miyamoto, K.2
Tsukamoto, H.3
-
49
-
-
0028141917
-
CCL4-induced liver cirrhosis and hepatocellular carcinoma in rats: Relationship to plasma zinc, copper and estradiol levels
-
Frezza EE, Gerunda GE, Farinati F, DeMaria N, Galligioni A, Plebani F, Giacomin A, Van Thiel DH. CCL4-induced liver cirrhosis and hepatocellular carcinoma in rats: relationship to plasma zinc, copper and estradiol levels. Hepatogastroenterology 41: 367-369, 1994.
-
(1994)
Hepatogastroenterology
, vol.41
, pp. 367-369
-
-
Frezza, E.E.1
Gerunda, G.E.2
Farinati, F.3
DeMaria, N.4
Galligioni, A.5
Plebani, F.6
Giacomin, A.7
van Thiel, D.H.8
-
50
-
-
0028795171
-
Concanavalin A-induced T-cell-mediated hepatic injury in mice: The role of tumor necrosis factor
-
Gantner F, Leist M, Lohse AW, Germann PG, Tiegs G. Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor. Hepatology 21: 190-198, 1995.
-
(1995)
Hepatology
, vol.21
, pp. 190-198
-
-
Gantner, F.1
Leist, M.2
Lohse, A.W.3
Germann, P.G.4
Tiegs, G.5
-
51
-
-
7044264899
-
Oxidative DNA damage and DNA repair enzyme expression are inversely related in murine models of fatty liver disease
-
Gao D, Wei C, Chen L, Huang J, Yang S, Diehl AM. Oxidative DNA damage and DNA repair enzyme expression are inversely related in murine models of fatty liver disease. Am J Physiol Gastrointest Liver Physiol 287: G1070-G1077, 2004.
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.287
-
-
Gao, D.1
Wei, C.2
Chen, L.3
Huang, J.4
Yang, S.5
Diehl, A.M.6
-
52
-
-
47649116115
-
Comparison of three research models of portal hypertension in mice: Macroscopic, histological and portal pressure evaluation
-
Geerts AM, Vanheule E, Praet M, Van Vlierberghe H, De Vos M, Colle I. Comparison of three research models of portal hypertension in mice: macroscopic, histological and portal pressure evaluation. Int J Exp Pathol 89: 251-263, 2008.
-
(2008)
Int J Exp Pathol
, vol.89
, pp. 251-263
-
-
Geerts, A.M.1
Vanheule, E.2
Praet, M.3
van Vlierberghe, H.4
de Vos, M.5
Colle, I.6
-
53
-
-
0034131557
-
Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
-
Gorelik L, Flavell RA. Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity 12: 171-181, 2000.
-
(2000)
Immunity
, vol.12
, pp. 171-181
-
-
Gorelik, L.1
Flavell, R.A.2
-
54
-
-
0035873731
-
Genetic regulation of autoimmune disease: BALB/c background TGF-beta 1-deficient mice develop necroinflammatory IFN-gamma-dependent hepatitis
-
Gorham JD, Lin JT, Sung JL, Rudner LA, French MA. Genetic regulation of autoimmune disease: BALB/c background TGF-beta 1-deficient mice develop necroinflammatory IFN-gamma-dependent hepatitis. J Immunol 166: 6413-6422, 2001.
-
(2001)
J Immunol
, vol.166
, pp. 6413-6422
-
-
Gorham, J.D.1
Lin, J.T.2
Sung, J.L.3
Rudner, L.A.4
French, M.A.5
-
55
-
-
33646539166
-
Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver
-
Gustot T, Lemmers A, Moreno C, Nagy N, Quertinmont E, Nicaise C, Franchimont D, Louis H, Deviere J, Le Moine O. Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver. Hepatology 43: 989-1000, 2006.
-
(2006)
Hepatology
, vol.43
, pp. 989-1000
-
-
Gustot, T.1
Lemmers, A.2
Moreno, C.3
Nagy, N.4
Quertinmont, E.5
Nicaise, C.6
Franchimont, D.7
Louis, H.8
Deviere, J.9
Le Moine, O.10
-
56
-
-
68049143345
-
-/- mice
-
-/- mice. Hepatology 49: 1972-1981, 2009.
-
(2009)
Hepatology
, vol.49
, pp. 1972-1981
-
-
Halilbasic, E.1
Fiorotto, R.2
Fickert, P.3
Marschall, H.U.4
Moustafa, T.5
Spirli, C.6
Fuchsbichler, A.7
Gumhold, J.8
Silbert, D.9
Zatloukal, K.10
Langner, C.11
Maitra, U.12
Denk, H.13
Hofmann, A.F.14
Strazzabosco, M.15
Trauner, M.16
-
57
-
-
77952576055
-
Mouse models for experimental autoimmune hepatitis: Limits and chances
-
Hardtke-Wolenski M, Jaeckel E. Mouse models for experimental autoimmune hepatitis: limits and chances. Dig Dis 28: 70-79, 2010.
-
(2010)
Dig Dis
, vol.28
, pp. 70-79
-
-
Hardtke-Wolenski, M.1
Jaeckel, E.2
-
58
-
-
79955554762
-
Animal models for the study of liver fibrosis: New insights from knockout mouse models
-
Hayashi H, Sakai T. Animal models for the study of liver fibrosis: new insights from knockout mouse models. Am J Physiol Gastrointest Liver Physiol 300: G729-G738, 2011.
-
(2011)
Am J Physiol Gastrointest Liver Physiol
, vol.300
-
-
Hayashi, H.1
Sakai, T.2
-
59
-
-
78651089694
-
Animal models of nonalcoholic fatty liver disease
-
Hebbard L, George J. Animal models of nonalcoholic fatty liver disease. Nat Rev Gastroenterol Hepatol 8: 35-44, 2010.
-
(2010)
Nat Rev Gastroenterol Hepatol
, vol.8
, pp. 35-44
-
-
Hebbard, L.1
George, J.2
-
60
-
-
0025144417
-
Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activator
-
Heckel JL, Sandgren EP, Degen JL, Palmiter RD, Brinster RL. Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activator. Cell 62: 447-456, 1990.
-
(1990)
Cell
, vol.62
, pp. 447-456
-
-
Heckel, J.L.1
Sandgren, E.P.2
Degen, J.L.3
Palmiter, R.D.4
Brinster, R.L.5
-
61
-
-
68849118378
-
Experimental mouse models for hepatocellular carcinoma research
-
Heindryckx F, Colle I, Van Vlierberghe H. Experimental mouse models for hepatocellular carcinoma research. Int J Exp Pathol 90: 367-386, 2009.
-
(2009)
Int J Exp Pathol
, vol.90
, pp. 367-386
-
-
Heindryckx, F.1
Colle, I.2
van Vlierberghe, H.3
-
62
-
-
0036892365
-
Genome-wide analysis of hepatic fibrosis in inbred mice identifies the susceptibility locus Hfib1 on chromosome 15
-
Hillebrandt S, Goos C, Matern S, Lammert F. Genome-wide analysis of hepatic fibrosis in inbred mice identifies the susceptibility locus Hfib1 on chromosome 15. Gastroenterology 123: 2041-2051, 2002.
-
(2002)
Gastroenterology
, vol.123
, pp. 2041-2051
-
-
Hillebrandt, S.1
Goos, C.2
Matern, S.3
Lammert, F.4
-
63
-
-
84861214016
-
The CYP2D6 animal model: How to induce autoimmune hepatitis in mice
-
doi: 10.3791/3644
-
Hintermann E, Ehser J, Christen U. The CYP2D6 animal model: how to induce autoimmune hepatitis in mice. J Vis Exp (60), e3644, doi: 10.3791/3644, 2012.
-
(2012)
J Vis Exp
, Issue.60
-
-
Hintermann, E.1
Ehser, J.2
Christen, U.3
-
64
-
-
45149109642
-
Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection
-
Holdener M, Hintermann E, Bayer M, Rhode A, Rodrigo E, Hintereder G, Johnson EF, Gonzalez FJ, Pfeilschifter J, Manns MP, Herrath MG, Christen U. Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection. J Exp Med 205: 1409-1422, 2008.
-
(2008)
J Exp Med
, vol.205
, pp. 1409-1422
-
-
Holdener, M.1
Hintermann, E.2
Bayer, M.3
Rhode, A.4
Rodrigo, E.5
Hintereder, G.6
Johnson, E.F.7
Gonzalez, F.J.8
Pfeilschifter, J.9
Manns, M.P.10
Herrath, M.G.11
Christen, U.12
-
65
-
-
0036288668
-
Leptin is required for fibrogenic re-sponses induced by thioacetamide in the murine liver
-
Honda H, Ikejima K, Hirose M, Yoshikawa M, Lang T, Enomoto N, Kitamura T, Takei Y, Sato N. Leptin is required for fibrogenic re-sponses induced by thioacetamide in the murine liver. Hepatology 36: 12-21, 2002.
-
(2002)
Hepatology
, vol.36
, pp. 12-21
-
-
Honda, H.1
Ikejima, K.2
Hirose, M.3
Yoshikawa, M.4
Lang, T.5
Enomoto, N.6
Kitamura, T.7
Takei, Y.8
Sato, N.9
-
66
-
-
85047694402
-
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
-
Horie Y, Suzuki A, Kataoka E, Sasaki T, Hamada K, Sasaki J, Mizuno K, Hasegawa G, Kishimoto H, Iizuka M, Naito M, Enomoto K, Watanabe S, Mak TW, Nakano T. Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas. J Clin Invest 113: 1774-1783, 2004.
-
(2004)
J Clin Invest
, vol.113
, pp. 1774-1783
-
-
Horie, Y.1
Suzuki, A.2
Kataoka, E.3
Sasaki, T.4
Hamada, K.5
Sasaki, J.6
Mizuno, K.7
Hasegawa, G.8
Kishimoto, H.9
Iizuka, M.10
Naito, M.11
Enomoto, K.12
Watanabe, S.13
Mak, T.W.14
Nakano, T.15
-
68
-
-
34249775833
-
Role of adipocytokines in hepatic fibrogenesis
-
Ikejima K, Okumura K, Kon K, Takei Y, Sato N. Role of adipocytokines in hepatic fibrogenesis. J Gastroenterol Hepatol 22, Suppl 1: S87-S92, 2007.
-
(2007)
J Gastroenterol Hepatol
, vol.22
, Issue.SUPPL. 1
-
-
Ikejima, K.1
Okumura, K.2
Kon, K.3
Takei, Y.4
Sato, N.5
-
69
-
-
0037080355
-
The hepatitis C virus (HCV)-Trimera mouse: A model for evaluation of agents against HCV
-
Ilan E, Arazi J, Nussbaum O, Zauberman A, Eren R, Lubin I, Neville L, Ben-Moshe O, Kischitzky A, Litchi A, Margalit I, Gopher J, Mounir S, Cai W, Daudi N, Eid A, Jurim O, Czerniak A, Galun E, Dagan S. The hepatitis C virus (HCV)-Trimera mouse: a model for evaluation of agents against HCV. J Infect Dis 185: 153-161, 2002.
-
(2002)
J Infect Dis
, vol.185
, pp. 153-161
-
-
Ilan, E.1
Arazi, J.2
Nussbaum, O.3
Zauberman, A.4
Eren, R.5
Lubin, I.6
Neville, L.7
Ben-Moshe, O.8
Kischitzky, A.9
Litchi, A.10
Margalit, I.11
Gopher, J.12
Mounir, S.13
Cai, W.14
Daudi, N.15
Eid, A.16
Jurim, O.17
Czerniak, A.18
Galun, E.19
Dagan, S.20
more..
-
70
-
-
0033030127
-
The hepatitis B virus-trimera mouse: A model for human HBV infection and evaluation of anti-HBV therapeutic agents
-
Ilan E, Burakova T, Dagan S, Nussbaum O, Lubin I, Eren R, Ben-Moshe O, Arazi J, Berr S, Neville L, Yuen L, Mansour TS, Gillard J, Eid A, Jurim O, Shouval D, Reisner Y, Galun E. The hepatitis B virus-trimera mouse: a model for human HBV infection and evaluation of anti-HBV therapeutic agents. Hepatology 29: 553-562, 1999.
-
(1999)
Hepatology
, vol.29
, pp. 553-562
-
-
Ilan, E.1
Burakova, T.2
Dagan, S.3
Nussbaum, O.4
Lubin, I.5
Eren, R.6
Ben-Moshe, O.7
Arazi, J.8
Berr, S.9
Neville, L.10
Yuen, L.11
Mansour, T.S.12
Gillard, J.13
Eid, A.14
Jurim, O.15
Shouval, D.16
Reisner, Y.17
Galun, E.18
-
71
-
-
0032146551
-
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
-
Iredale JP, Benyon RC, Pickering J, McCullen M, Northrop M, Pawley S, Hovell C, Arthur MP. Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest 102: 538-549, 1998.
-
(1998)
J Clin Invest
, vol.102
, pp. 538-549
-
-
Iredale, J.P.1
Benyon, R.C.2
Pickering, J.3
McCullen, M.4
Northrop, M.5
Pawley, S.6
Hovell, C.7
Arthur, M.P.8
-
72
-
-
33646673596
-
NOD c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis
-
Irie J, Wu Y, Wicker LS, Rainbow D, Nalesnik MA, Hirsch R, Peterson LB, Leung PS, Cheng C, Mackay IR, Gershwin ME, Ridgway WM. NOD. c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis. J Exp Med 203: 1209-1219, 2006.
-
(2006)
J Exp Med
, vol.203
, pp. 1209-1219
-
-
Irie, J.1
Wu, Y.2
Wicker, L.S.3
Rainbow, D.4
Nalesnik, M.A.5
Hirsch, R.6
Peterson, L.B.7
Leung, P.S.8
Cheng, C.9
McKay, I.R.10
Gershwin, M.E.11
Ridgway, W.M.12
-
73
-
-
0035083958
-
Apoptosis of hepatic stellate cells: Involvement in resolution of biliary fibrosis and regulation by soluble growth factors
-
Issa R, Williams E, Trim N, Kendall T, Arthur MJ, Reichen J, Benyon RC, Iredale JP. Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors. Gut 48: 548-557, 2001.
-
(2001)
Gut
, vol.48
, pp. 548-557
-
-
Issa, R.1
Williams, E.2
Trim, N.3
Kendall, T.4
Arthur, M.J.5
Reichen, J.6
Benyon, R.C.7
Iredale, J.P.8
-
74
-
-
33947137852
-
Longitudinal analysis of murine steatohepatitis model induced by chronic exposure to high-fat diet
-
Ito M, Suzuki J, Tsujioka S, Sasaki M, Gomori A, Shirakura T, Hirose H, Ishihara A, Iwaasa H, Kanatani A. Longitudinal analysis of murine steatohepatitis model induced by chronic exposure to high-fat diet. Hepatol Res 37: 50-57, 2007.
-
(2007)
Hepatol Res
, vol.37
, pp. 50-57
-
-
Ito, M.1
Suzuki, J.2
Tsujioka, S.3
Sasaki, M.4
Gomori, A.5
Shirakura, T.6
Hirose, H.7
Ishihara, A.8
Iwaasa, H.9
Kanatani, A.10
-
75
-
-
80055004124
-
Melanocortin 4 receptor-deficient mice as a novel mouse model of nonalcoholic steatohepatitis
-
Itoh M, Suganami T, Nakagawa N, Tanaka M, Yamamoto Y, Kamei Y, Terai S, Sakaida I, Ogawa Y. Melanocortin 4 receptor-deficient mice as a novel mouse model of nonalcoholic steatohepatitis. Am J Pathol 179: 2454-2463, 2011.
-
(2011)
Am J Pathol
, vol.179
, pp. 2454-2463
-
-
Itoh, M.1
Suganami, T.2
Nakagawa, N.3
Tanaka, M.4
Yamamoto, Y.5
Kamei, Y.6
Terai, S.7
Sakaida, I.8
Ogawa, Y.9
-
77
-
-
0021827737
-
A dimethylnitrosamine-induced model of cirrhosis and portal hypertension in the rat
-
Jenkins SA, Grandison A, Baxter JN, Day DW, Taylor I, Shields R. A dimethylnitrosamine-induced model of cirrhosis and portal hypertension in the rat. J Hepatol 1: 489-499, 1985.
-
(1985)
J Hepatol
, vol.1
, pp. 489-499
-
-
Jenkins, S.A.1
Grandison, A.2
Baxter, J.N.3
Day, D.W.4
Taylor, I.5
Shields, R.6
-
78
-
-
17844403507
-
Mild hepatic fibrosis in cholesterol and sodium cholate diet-fed rats
-
Jeong WI, Jeong DH, Do SH, Kim YK, Park HY, Kwon OD, Kim TH, Jeong KS. Mild hepatic fibrosis in cholesterol and sodium cholate diet-fed rats. J Vet Med Sci 67: 235-242, 2005.
-
(2005)
J Vet Med Sci
, vol.67
, pp. 235-242
-
-
Jeong, W.I.1
Jeong, D.H.2
Do, S.H.3
Kim, Y.K.4
Park, H.Y.5
Kwon, O.D.6
Kim, T.H.7
Jeong, K.S.8
-
79
-
-
0032530110
-
Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: Implications for gene therapy
-
Kafri T, Morgan D, Krahl T, Sarvetnick N, Sherman L, Verma I. Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy. Proc Natl Acad Sci USA 95: 11377-11382, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11377-11382
-
-
Kafri, T.1
Morgan, D.2
Krahl, T.3
Sarvetnick, N.4
Sherman, L.5
Verma, I.6
-
80
-
-
0033109090
-
TGF-β1 in liver fibrosis: An inducible transgenic mouse model to study liver fibrogenesis
-
Kanzler S, Lohse AW, Keil A, Henninger J, Dienes HP, Schirmacher P, Rose-John S, zum Buschenfelde KH, Blessing M. TGF-β1 in liver fibrosis: an inducible transgenic mouse model to study liver fibrogenesis. Am J Physiol Gastrointest Liver Physiol 276: G1059-G1068, 1999.
-
(1999)
Am J Physiol Gastrointest Liver Physiol
, vol.276
-
-
Kanzler, S.1
Lohse, A.W.2
Keil, A.3
Henninger, J.4
Dienes, H.P.5
Schirmacher, P.6
Rose-John, S.7
Zum Buschenfelde, K.H.8
Blessing, M.9
-
81
-
-
78649736831
-
Persistent expression of the full genome of hepatitis C virus in B cells induces spontaneous development of B-cell lymphomas in vivo
-
Kasama Y, Sekiguchi S, Saito M, Tanaka K, Satoh M, Kuwahara K, Sakaguchi N, Takeya M, Hiasa Y, Kohara M, Tsukiyama-Kohara K. Persistent expression of the full genome of hepatitis C virus in B cells induces spontaneous development of B-cell lymphomas in vivo. Blood 116: 4926-4933, 2010.
-
(2010)
Blood
, vol.116
, pp. 4926-4933
-
-
Kasama, Y.1
Sekiguchi, S.2
Saito, M.3
Tanaka, K.4
Satoh, M.5
Kuwahara, K.6
Sakaguchi, N.7
Takeya, M.8
Hiasa, Y.9
Kohara, M.10
Tsukiyama-Kohara, K.11
-
82
-
-
4644370807
-
Lack of peroxisome proliferator-activated receptor alpha in mice enhances methionine and choline deficient dietinduced steatohepatitis
-
Kashireddy PV, Rao MS. Lack of peroxisome proliferator-activated receptor alpha in mice enhances methionine and choline deficient dietinduced steatohepatitis. Hepatol Res 30: 104-110, 2004.
-
(2004)
Hepatol Res
, vol.30
, pp. 104-110
-
-
Kashireddy, P.V.1
Rao, M.S.2
-
83
-
-
36248962566
-
Molecular mechanisms of liver carcinogenesis in the mdr2-knockout mice
-
Katzenellenbogen M, Mizrahi L, Pappo O, Klopstock N, Olam D, Jacob-Hirsch J, Amariglio N, Rechavi G, Domany E, Galun E, Goldenberg D. Molecular mechanisms of liver carcinogenesis in the mdr2-knockout mice. Mol Cancer Res 5: 1159-1170, 2007.
-
(2007)
Mol Cancer Res
, vol.5
, pp. 1159-1170
-
-
Katzenellenbogen, M.1
Mizrahi, L.2
Pappo, O.3
Klopstock, N.4
Olam, D.5
Jacob-Hirsch, J.6
Amariglio, N.7
Rechavi, G.8
Domany, E.9
Galun, E.10
Goldenberg, D.11
-
84
-
-
0032699670
-
Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting
-
Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli W. Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J Clin Invest 103: 1489-1498, 1999.
-
(1999)
J Clin Invest
, vol.103
, pp. 1489-1498
-
-
Kersten, S.1
Seydoux, J.2
Peters, J.M.3
Gonzalez, F.J.4
Desvergne, B.5
Wahli, W.6
-
85
-
-
77957946415
-
Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3
-
Ki SH, Park O, Zheng M, Morales-Ibanez O, Kolls JK, Bataller R, Gao B. Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: role of signal transducer and activator of transcription 3. Hepatology 52: 1291-1300, 2010.
-
(2010)
Hepatology
, vol.52
, pp. 1291-1300
-
-
Ki, S.H.1
Park, O.2
Zheng, M.3
Morales-Ibanez, O.4
Kolls, J.K.5
Bataller, R.6
Gao, B.7
-
86
-
-
44649144640
-
Fatal autoimmune hepatitis induced by concurrent loss of naturally arising regulatory T cells and PD-1-mediated signaling
-
Kido M, Watanabe N, Okazaki T, Akamatsu T, Tanaka J, Saga K, Nishio A, Honjo T, Chiba T. Fatal autoimmune hepatitis induced by concurrent loss of naturally arising regulatory T cells and PD-1-mediated signaling. Gastroenterology 135: 1333-1343, 2008.
-
(2008)
Gastroenterology
, vol.135
, pp. 1333-1343
-
-
Kido, M.1
Watanabe, N.2
Okazaki, T.3
Akamatsu, T.4
Tanaka, J.5
Saga, K.6
Nishio, A.7
Honjo, T.8
Chiba, T.9
-
87
-
-
0344010170
-
Rodent nutritional model of non-alcoholic steatohepatitis: Species, strain and sex difference studies
-
Kirsch R, Clarkson V, Shephard EG, Marais DA, Jaffer MA, Woodburne VE, Kirsch RE, Hall Pde L. Rodent nutritional model of non-alcoholic steatohepatitis: species, strain and sex difference studies. J Gastroenterol Hepatol 18: 1272-1282, 2003.
-
(2003)
J Gastroenterol Hepatol
, vol.18
, pp. 1272-1282
-
-
Kirsch, R.1
Clarkson, V.2
Shephard, E.G.3
Marais, D.A.4
Jaffer, M.A.5
Woodburne, V.E.6
Kirsch, R.E.7
Hall Pde, L.8
-
88
-
-
77956634470
-
High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis
-
Kohli R, Kirby M, Xanthakos SA, Softic S, Feldstein AE, Saxena V, Tang PH, Miles L, Miles MV, Balistreri WF, Woods SC, Seeley RJ. High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. Hepatology 52: 934-944, 2010.
-
(2010)
Hepatology
, vol.52
, pp. 934-944
-
-
Kohli, R.1
Kirby, M.2
Xanthakos, S.A.3
Softic, S.4
Feldstein, A.E.5
Saxena, V.6
Tang, P.H.7
Miles, L.8
Miles, M.V.9
Balistreri, W.F.10
Woods, S.C.11
Seeley, R.J.12
-
89
-
-
0034569372
-
Development of an intragastric enteral model in the mouse: Studies of alcohol-induced liver disease using knockout technology
-
Kono H, Bradford BU, Rusyn I, Fujii H, Matsumoto Y, Yin M, Thurman RG. Development of an intragastric enteral model in the mouse: studies of alcohol-induced liver disease using knockout technology. J Hepatobiliary Pancreat Surg 7: 395-400, 2000.
-
(2000)
J Hepatobiliary Pancreat Surg
, vol.7
, pp. 395-400
-
-
Kono, H.1
Bradford, B.U.2
Rusyn, I.3
Fujii, H.4
Matsumoto, Y.5
Yin, M.6
Thurman, R.G.7
-
90
-
-
0033802236
-
NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease
-
Kono H, Rusyn I, Yin M, Gabele E, Yamashina S, Dikalova A, Kadiiska MB, Connor HD, Mason RP, Segal BH, Bradford BU, Holland SM, Thurman RG. NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease. J Clin Invest 106: 867-872, 2000.
-
(2000)
J Clin Invest
, vol.106
, pp. 867-872
-
-
Kono, H.1
Rusyn, I.2
Yin, M.3
Gabele, E.4
Yamashina, S.5
Dikalova, A.6
Kadiiska, M.B.7
Connor, H.D.8
Mason, R.P.9
Segal, B.H.10
Bradford, B.U.11
Holland, S.M.12
Thurman, R.G.13
-
91
-
-
0021238490
-
Prolonged bile duct obstruction: A new experimental model for cirrhosis in the rat
-
Kountouras J, Billing BH, Scheuer PJ. Prolonged bile duct obstruction: a new experimental model for cirrhosis in the rat. Br J Exp Pathol 65: 305-311, 1984.
-
(1984)
Br J Exp Pathol
, vol.65
, pp. 305-311
-
-
Kountouras, J.1
Billing, B.H.2
Scheuer, P.J.3
-
92
-
-
34250634419
-
New animal models for hepatitis C viral infection and pathogenesis studies
-
Kremsdorf D, Brezillon N. New animal models for hepatitis C viral infection and pathogenesis studies. World J Gastroenterol 13: 2427-2435, 2007.
-
(2007)
World J Gastroenterol
, vol.13
, pp. 2427-2435
-
-
Kremsdorf, D.1
Brezillon, N.2
-
93
-
-
0039469942
-
alpha-Hydroxylation pathway in the in vitro metabolism of carcinogenic nitrosamines: N-nitrosodimethylamine and N-nitroso-Nmethylaniline
-
Kroeger-Koepke MB, Koepke SR, McClusky GA, Magee PN, Michejda CJ. alpha-Hydroxylation pathway in the in vitro metabolism of carcinogenic nitrosamines: N-nitrosodimethylamine and N-nitroso-Nmethylaniline. Proc Natl Acad Sci USA 78: 6489-6493, 1981.
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 6489-6493
-
-
Kroeger-Koepke, M.B.1
Koepke, S.R.2
McClusky, G.A.3
Magee, P.N.4
Michejda, C.J.5
-
94
-
-
84855691892
-
New developments in HCV therapy
-
Kronenberger B, Zeuzem S. New developments in HCV therapy. J Viral Hepat 19, Suppl 1: 48-51, 2012.
-
(2012)
J Viral Hepat
, vol.19
, Issue.SUPPL. 1
, pp. 48-51
-
-
Kronenberger, B.1
Zeuzem, S.2
-
95
-
-
0027531528
-
Transforming growth factor beta-1 null mutation in mice causes excessive inflammatory response and early death
-
Kulkarni AB, Huh CG, Becker D, Geiser A, Lyght M, Flanders KC, Roberts AB, Sporn MB, Ward JM, Karlsson S. Transforming growth factor beta-1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci USA 90: 770-774, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 770-774
-
-
Kulkarni, A.B.1
Huh, C.G.2
Becker, D.3
Geiser, A.4
Lyght, M.5
Flanders, K.C.6
Roberts, A.B.7
Sporn, M.B.8
Ward, J.M.9
Karlsson, S.10
-
96
-
-
0030017301
-
Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A
-
Kusters S, Gantner F, Kunstle G, Tiegs G. Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A. Gastroenterology 111: 462-471, 1996.
-
(1996)
Gastroenterology
, vol.111
, pp. 462-471
-
-
Kusters, S.1
Gantner, F.2
Kunstle, G.3
Tiegs, G.4
-
97
-
-
0346765512
-
Viral hepatitis B
-
Lai CL, Ratziu V, Yuen MF, Poynard T. Viral hepatitis B. Lancet 362: 2089-2094, 2003.
-
(2003)
Lancet
, vol.362
, pp. 2089-2094
-
-
Lai, C.L.1
Ratziu, V.2
Yuen, M.F.3
Poynard, T.4
-
98
-
-
1442355466
-
-/- mice: A model for low phospholipid-associated cholelithiasis
-
-/- mice: a model for low phospholipid-associated cholelithiasis. Hepatology 39: 117-128, 2004.
-
(2004)
Hepatology
, vol.39
, pp. 117-128
-
-
Lammert, F.1
Wang, D.Q.2
Hillebrandt, S.3
Geier, A.4
Fickert, P.5
Trauner, M.6
Matern, S.7
Paigen, B.8
Carey, M.C.9
-
99
-
-
56549117448
-
Animal models of NASH: Getting both pathology and metabolic context right
-
Larter CZ, Yeh MM. Animal models of NASH: getting both pathology and metabolic context right. J Gastroenterol Hepatol 23: 1635-1648, 2008.
-
(2008)
J Gastroenterol Hepatol
, vol.23
, pp. 1635-1648
-
-
Larter, C.Z.1
Yeh, M.M.2
-
100
-
-
70349684935
-
Roles of adipose restriction and metabolic factors in progression of steatosis to steatohepatitis in obese, diabetic mice
-
Larter CZ, Yeh MM, Van Rooyen DM, Teoh NC, Brooling J, Hou JY, Williams J, Clyne M, Nolan CJ, Farrell GC. Roles of adipose restriction and metabolic factors in progression of steatosis to steatohepatitis in obese, diabetic mice. J Gastroenterol Hepatol 24: 1658-1668, 2009.
-
(2009)
J Gastroenterol Hepatol
, vol.24
, pp. 1658-1668
-
-
Larter, C.Z.1
Yeh, M.M.2
van Rooyen, D.M.3
Teoh, N.C.4
Brooling, J.5
Hou, J.Y.6
Williams, J.7
Clyne, M.8
Nolan, C.J.9
Farrell, G.C.10
-
101
-
-
48449096011
-
MCD-induced steatohepatitis is associated with hepatic adiponectin resistance and adipogenic transformation of hepatocytes
-
Larter CZ, Yeh MM, Williams J, Bell-Anderson KS, Farrell GC. MCD-induced steatohepatitis is associated with hepatic adiponectin resistance and adipogenic transformation of hepatocytes. J Hepatol 49: 407-416, 2008.
-
(2008)
J Hepatol
, vol.49
, pp. 407-416
-
-
Larter, C.Z.1
Yeh, M.M.2
Williams, J.3
Bell-Anderson, K.S.4
Farrell, G.C.5
-
102
-
-
0036022846
-
Leptin is essential for the hepatic fibrogenic response to chronic liver injury
-
Leclercq IA, Farrell GC, Schriemer R, Robertson GR. Leptin is essential for the hepatic fibrogenic response to chronic liver injury. J Hepatol 37: 206-213, 2002.
-
(2002)
J Hepatol
, vol.37
, pp. 206-213
-
-
Leclercq, I.A.1
Farrell, G.C.2
Schriemer, R.3
Robertson, G.R.4
-
103
-
-
33845788135
-
Intrahepatic insulin resistance in a murine model of steatohepatitis: Effect of PPARgamma agonist pioglitazone
-
Leclercq IA, Lebrun VA, Starkel P, Horsmans YJ. Intrahepatic insulin resistance in a murine model of steatohepatitis: effect of PPARgamma agonist pioglitazone. Lab Invest 87: 56-65, 2007.
-
(2007)
Lab Invest
, vol.87
, pp. 56-65
-
-
Leclercq, I.A.1
Lebrun, V.A.2
Starkel, P.3
Horsmans, Y.J.4
-
104
-
-
0020696022
-
Hepatic fibrosis after long-term administration of ethanol and moderate vitamin A supplementation in the rat
-
Leo MA, Lieber CS. Hepatic fibrosis after long-term administration of ethanol and moderate vitamin A supplementation in the rat. Hepatology 3: 1-11, 1983.
-
(1983)
Hepatology
, vol.3
, pp. 1-11
-
-
Leo, M.A.1
Lieber, C.S.2
-
105
-
-
79958268921
-
Animal models in the study of hepatitis C virus-associated liver pathologies
-
Lerat H, Higgs M, Pawlotsky JM. Animal models in the study of hepatitis C virus-associated liver pathologies. Expert Rev Gastroenterol Hepatol 5: 341-352, 2011.
-
(2011)
Expert Rev Gastroenterol Hepatol
, vol.5
, pp. 341-352
-
-
Lerat, H.1
Higgs, M.2
Pawlotsky, J.M.3
-
106
-
-
84868519185
-
Animal models of primary biliary cirrhosis: Materials and methods
-
Leung PS, Yang GX, Dhirapong A, Tsuneyama K, Ridgway WM, Gershwin ME. Animal models of primary biliary cirrhosis: materials and methods. Methods Mol Biol 900: 291-316, 2012.
-
(2012)
Methods Mol Biol
, vol.900
, pp. 291-316
-
-
Leung, P.S.1
Yang, G.X.2
Dhirapong, A.3
Tsuneyama, K.4
Ridgway, W.M.5
Gershwin, M.E.6
-
107
-
-
0025801063
-
Biliary tract disease in rats with experimental small bowel bacterial overgrowth
-
Lichtman SN, Keku J, Clark RL, Schwab JH, Sartor RB. Biliary tract disease in rats with experimental small bowel bacterial overgrowth. Hepatology 13: 766-772, 1991.
-
(1991)
Hepatology
, vol.13
, pp. 766-772
-
-
Lichtman, S.N.1
Keku, J.2
Clark, R.L.3
Schwab, J.H.4
Sartor, R.B.5
-
108
-
-
0020395484
-
The feeding of alcohol in liquid diets: Two decades of applications and 1982 update
-
Lieber CS, DeCarli LM. The feeding of alcohol in liquid diets: two decades of applications and 1982 update. Alcohol Clin Exp Res 6: 523-531, 1982.
-
(1982)
Alcohol Clin Exp Res
, vol.6
, pp. 523-531
-
-
Lieber, C.S.1
DeCarli, L.M.2
-
110
-
-
1242290584
-
Model of nonalcoholic steatohepatitis
-
Lieber CS, Leo MA, Mak KM, Xu Y, Cao Q, Ren C, Ponomarenko A, DeCarli LM. Model of nonalcoholic steatohepatitis. Am J Clin Nutr 79: 502-509, 2004.
-
(2004)
Am J Clin Nutr
, vol.79
, pp. 502-509
-
-
Lieber, C.S.1
Leo, M.A.2
Mak, K.M.3
Xu, Y.4
Cao, Q.5
Ren, C.6
Ponomarenko, A.7
DeCarli, L.M.8
-
111
-
-
77952096918
-
The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome
-
Lim JS, Mietus-Snyder M, Valente A, Schwarz JM, Lustig RH. The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome. Nat Rev Gastroenterol Hepatol 7: 251-264, 2010.
-
(2010)
Nat Rev Gastroenterol Hepatol
, vol.7
, pp. 251-264
-
-
Lim, J.S.1
Mietus-Snyder, M.2
Valente, A.3
Schwarz, J.M.4
Lustig, R.H.5
-
112
-
-
34249799917
-
The physiology of obese-hyperglycemic mice [ob/ob mice]
-
Lindstrom P. The physiology of obese-hyperglycemic mice [ob/ob mice]. ScientificWorldJournal 7: 666-685, 2007.
-
(2007)
ScientificWorldJournal
, vol.7
, pp. 666-685
-
-
Lindstrom, P.1
-
113
-
-
34249681974
-
Pathogenesis of NASH: Animal models
-
London RM, George J. Pathogenesis of NASH: animal models. Clin Liver Dis 11: 55-74, viii, 2007.
-
(2007)
Clin Liver Dis
, vol.11
-
-
London, R.M.1
George, J.2
-
114
-
-
0030966908
-
Production and role of interleukin-10 in concanavalin A-induced hepatitis in mice
-
Louis H, Le Moine O, Peny MO, Quertinmont E, Fokan D, Goldman M, Deviere J. Production and role of interleukin-10 in concanavalin A-induced hepatitis in mice. Hepatology 25: 1382-1389, 1997.
-
(1997)
Hepatology
, vol.25
, pp. 1382-1389
-
-
Louis, H.1
Le Moine, O.2
Peny, M.O.3
Quertinmont, E.4
Fokan, D.5
Goldman, M.6
Deviere, J.7
-
115
-
-
80053314254
-
Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice
-
Louvet A, Teixeira-Clerc F, Chobert MN, Deveaux V, Pavoine C, Zimmer A, Pecker F, Mallat A, Lotersztajn S. Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice. Hepatology 54: 1217-1226, 2011.
-
(2011)
Hepatology
, vol.54
, pp. 1217-1226
-
-
Louvet, A.1
Teixeira-Clerc, F.2
Chobert, M.N.3
Deveaux, V.4
Pavoine, C.5
Zimmer, A.6
Pecker, F.7
Mallat, A.8
Lotersztajn, S.9
-
116
-
-
0035853773
-
Inhibition of cytochrome c release in Fas-mediated signaling pathway in transgenic mice induced to express hepatitis C viral proteins
-
Machida K, Tsukiyama-Kohara K, Seike E, Tone S, Shibasaki F, Shimizu M, Takahashi H, Hayashi Y, Funata N, Taya C, Yonekawa H, Kohara M. Inhibition of cytochrome c release in Fas-mediated signaling pathway in transgenic mice induced to express hepatitis C viral proteins. J Biol Chem 276: 12140-12146, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 12140-12146
-
-
McHida, K.1
Tsukiyama-Kohara, K.2
Seike, E.3
Tone, S.4
Shibasaki, F.5
Shimizu, M.6
Takahashi, H.7
Hayashi, Y.8
Funata, N.9
Taya, C.10
Yonekawa, H.11
Kohara, M.12
-
117
-
-
42149161075
-
An update on primary sclerosing cholangitis
-
Maggs JR, Chapman RW. An update on primary sclerosing cholangitis. Curr Opin Gastroenterol 24: 377-383, 2008.
-
(2008)
Curr Opin Gastroenterol
, vol.24
, pp. 377-383
-
-
Maggs, J.R.1
Chapman, R.W.2
-
118
-
-
77952711598
-
Diagnosis and management of autoimmune hepatitis
-
Manns MP, Czaja AJ, Gorham JD, Krawitt EL, Mieli-Vergani G, Vergani D, Vierling JM. Diagnosis and management of autoimmune hepatitis. Hepatology 51: 2193-2213, 2010.
-
(2010)
Hepatology
, vol.51
, pp. 2193-2213
-
-
Manns, M.P.1
Czaja, A.J.2
Gorham, J.D.3
Krawitt, E.L.4
Mieli-Vergani, G.5
Vergani, D.6
Vierling, J.M.7
-
119
-
-
0037382786
-
Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome
-
Marchesini G, Bugianesi E, Forlani G, Cerrelli F, Lenzi M, Manini R, Natale S, Vanni E, Villanova N, Melchionda N, Rizzetto M. Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology 37: 917-923, 2003.
-
(2003)
Hepatology
, vol.37
, pp. 917-923
-
-
Marchesini, G.1
Bugianesi, E.2
Forlani, G.3
Cerrelli, F.4
Lenzi, M.5
Manini, R.6
Natale, S.7
Vanni, E.8
Villanova, N.9
Melchionda, N.10
Rizzetto, M.11
-
120
-
-
36348935003
-
Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet
-
Matsuzawa N, Takamura T, Kurita S, Misu H, Ota T, Ando H, Yokoyama M, Honda M, Zen Y, Nakanuma Y, Miyamoto K, Kaneko S. Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet. Hepatology 46: 1392-1403, 2007.
-
(2007)
Hepatology
, vol.46
, pp. 1392-1403
-
-
Matsuzawa, N.1
Takamura, T.2
Kurita, S.3
Misu, H.4
Ota, T.5
Ando, H.6
Yokoyama, M.7
Honda, M.8
Zen, Y.9
Nakanuma, Y.10
Miyamoto, K.11
Kaneko, S.12
-
121
-
-
0028028436
-
Mice with homozygous disruption of the mdr2 P-glycoprotein gene A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis
-
Mauad TH, van Nieuwkerk CM, Dingemans KP, Smit JJ, Schinkel AH, Notenboom RG, van den Bergh Weerman MA, Verkruisen RP, Groen AK, Oude Elferink RP, van der Valk MA, Borst P, Offerhaus GJ. Mice with homozygous disruption of the mdr2 P-glycoprotein gene A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis. Am J Pathol 145: 1237-1245, 1994.
-
(1994)
Am J Pathol
, vol.145
, pp. 1237-1245
-
-
Mauad, T.H.1
van Nieuwkerk, C.M.2
Dingemans, K.P.3
Smit, J.J.4
Schinkel, A.H.5
Notenboom, R.G.6
van den Bergh Weerman, M.A.7
Verkruisen, R.P.8
Groen, A.K.9
Oude Elferink, R.P.10
van der Valk, M.A.11
Borst, P.12
Offerhaus, G.J.13
-
122
-
-
0034710792
-
Oxidized LDL induces an oxidative stress and activates the tumor suppressor p53 in MRC5 human fibroblasts
-
Maziere C, Meignotte A, Dantin F, Conte MA, Maziere JC. Oxidized LDL induces an oxidative stress and activates the tumor suppressor p53 in MRC5 human fibroblasts. Biochem Biophys Res Commun 276: 718-723, 2000.
-
(2000)
Biochem Biophys Res Commun
, vol.276
, pp. 718-723
-
-
Maziere, C.1
Meignotte, A.2
Dantin, F.3
Conte, M.A.4
Maziere, J.C.5
-
123
-
-
0014592402
-
An improved method for producing cirrhosis of the liver in rats by simultaneous administration of carbon tetrachloride and phenobarbitone
-
Sutton Instant cirrhosis PM
-
McLean EK, McLean AE, Sutton Instant cirrhosis PM. An improved method for producing cirrhosis of the liver in rats by simultaneous administration of carbon tetrachloride and phenobarbitone. Br J Exp Pathol 50: 502-506, 1969.
-
(1969)
Br J Exp Pathol
, vol.50
, pp. 502-506
-
-
McLean, E.K.1
McLean, A.E.2
-
124
-
-
17944379233
-
Hepatitis C virus replication in mice with chimeric human livers
-
Mercer DF, Schiller DE, Elliott JF, Douglas DN, Hao C, Rinfret A, Addison WR, Fischer KP, Churchill TA, Lakey JR, Tyrrell DL, Kneteman NM. Hepatitis C virus replication in mice with chimeric human livers. Nat Med 7: 927-933, 2001.
-
(2001)
Nat Med
, vol.7
, pp. 927-933
-
-
Mercer, D.F.1
Schiller, D.E.2
Elliott, J.F.3
Douglas, D.N.4
Hao, C.5
Rinfret, A.6
Addison, W.R.7
Fischer, K.P.8
Churchill, T.A.9
Lakey, J.R.10
Tyrrell, D.L.11
Kneteman, N.M.12
-
125
-
-
56349163205
-
The human liver-uPA-SCID mouse: A model for the evaluation of antiviral compounds against HBV and HCV
-
Meuleman P, Leroux-Roels G. The human liver-uPA-SCID mouse: a model for the evaluation of antiviral compounds against HBV and HCV. Antiviral Res 80: 231-238, 2008.
-
(2008)
Antiviral Res
, vol.80
, pp. 231-238
-
-
Meuleman, P.1
Leroux-Roels, G.2
-
126
-
-
16244415868
-
Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera
-
Meuleman P, Libbrecht L, De Vos R, de Hemptinne B, Gevaert K, Vandekerckhove J, Roskams T, Leroux-Roels G. Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera. Hepatology 41: 847-856, 2005.
-
(2005)
Hepatology
, vol.41
, pp. 847-856
-
-
Meuleman, P.1
Libbrecht, L.2
de Vos, R.3
de Hemptinne, B.4
Gevaert, K.5
Vandekerckhove, J.6
Roskams, T.7
Leroux-Roels, G.8
-
128
-
-
79952484948
-
B cells promote hepatic inflammation, biliary cyst formation, and salivary gland inflammation in the NOD. c3c4 model of autoimmune cholangitis
-
Moritoki Y, Tsuda M, Tsuneyama K, Zhang W, Yoshida K, Lian ZX, Yang GX, Ridgway WM, Wicker LS, Ansari AA, Gershwin ME. B cells promote hepatic inflammation, biliary cyst formation, and salivary gland inflammation in the NOD. c3c4 model of autoimmune cholangitis. Cell Immunol 268: 16-23, 2011.
-
(2011)
Cell Immunol
, vol.268
, pp. 16-23
-
-
Moritoki, Y.1
Tsuda, M.2
Tsuneyama, K.3
Zhang, W.4
Yoshida, K.5
Lian, Z.X.6
Yang, G.X.7
Ridgway, W.M.8
Wicker, L.S.9
Ansari, A.A.10
Gershwin, M.E.11
-
129
-
-
33645347305
-
Liver-stage development of Plasmodium falciparum, in a humanized mouse model
-
Morosan S, Hez-Deroubaix S, Lunel F, Renia L, Giannini C, Van Rooijen N, Battaglia S, Blanc C, Eling W, Sauerwein R, Hannoun L, Belghiti J, Brechot C, Kremsdorf D, Druilhe P. Liver-stage development of Plasmodium falciparum, in a humanized mouse model. J Infect Dis 193: 996-1004, 2006.
-
(2006)
J Infect Dis
, vol.193
, pp. 996-1004
-
-
Morosan, S.1
Hez-Deroubaix, S.2
Lunel, F.3
Renia, L.4
Giannini, C.5
van Rooijen, N.6
Battaglia, S.7
Blanc, C.8
Eling, W.9
Sauerwein, R.10
Hannoun, L.11
Belghiti, J.12
Brechot, C.13
Kremsdorf, D.14
Druilhe, P.15
-
130
-
-
0023751476
-
Thioacetamideinduced cirrhosis-like liver lesions in rats-usefulness and reliability of this animal model
-
Muller A, Machnik F, Zimmermann T, Schubert H. Thioacetamideinduced cirrhosis-like liver lesions in rats-usefulness and reliability of this animal model. Exp Pathol (Jena) 34: 229-236, 1988.
-
(1988)
Exp Pathol (Jena)
, vol.34
, pp. 229-236
-
-
Muller, A.1
McHnik, F.2
Zimmermann, T.3
Schubert, H.4
-
131
-
-
84858784269
-
Genetically modified mouse models for the study of nonalcoholic fatty liver disease
-
Nagarajan P, Mahesh Kumar MJ, Venkatesan R, Majundar SS, Juyal RC. Genetically modified mouse models for the study of nonalcoholic fatty liver disease. World J Gastroenterol 18: 1141-1153, 2012.
-
(2012)
World J Gastroenterol
, vol.18
, pp. 1141-1153
-
-
Nagarajan, P.1
Mahesh Kumar, M.J.2
Venkatesan, R.3
Majundar, S.S.4
Juyal, R.C.5
-
132
-
-
34347339578
-
Autoimmune cholangitis in NOD. c3c4 mice is associated with cholangiocyte-specific Fas antigen deficiency
-
Nakagome Y, Ueno Y, Kogure T, Fukushima K, Moritoki Y, Ridgway WM, Eric Gershwin M, Shimosegawa T. Autoimmune cholangitis in NOD. c3c4 mice is associated with cholangiocyte-specific Fas antigen deficiency. J Autoimmun 29: 20-29, 2007.
-
(2007)
J Autoimmun
, vol.29
, pp. 20-29
-
-
Nakagome, Y.1
Ueno, Y.2
Kogure, T.3
Fukushima, K.4
Moritoki, Y.5
Ridgway, W.M.6
Eric Gershwin, M.7
Shimosegawa, T.8
-
133
-
-
1642321982
-
IL-2, regulatory T cells, and tolerance
-
Nelson BH. IL-2, regulatory T cells, and tolerance. J Immunol 172: 3983-3988, 2004.
-
(2004)
J Immunol
, vol.172
, pp. 3983-3988
-
-
Nelson, B.H.1
-
134
-
-
41249102034
-
Experimental models of hepatocellular carcinoma
-
Newell P, Villanueva A, Friedman SL, Koike K, Llovet JM. Experimental models of hepatocellular carcinoma. J Hepatol 48: 858-879, 2008.
-
(2008)
J Hepatol
, vol.48
, pp. 858-879
-
-
Newell, P.1
Villanueva, A.2
Friedman, S.L.3
Koike, K.4
Llovet, J.M.5
-
135
-
-
34548565932
-
Involvement of sex, strain and age factors in high fat diet-induced obesity in C57BL/6J and BALB/cA mice
-
Nishikawa S, Yasoshima A, Doi K, Nakayama H, Uetsuka K. Involvement of sex, strain and age factors in high fat diet-induced obesity in C57BL/6J and BALB/cA mice. Exp Anim 56: 263-272, 2007.
-
(2007)
Exp Anim
, vol.56
, pp. 263-272
-
-
Nishikawa, S.1
Yasoshima, A.2
Doi, K.3
Nakayama, H.4
Uetsuka, K.5
-
136
-
-
0025322603
-
Synthetic low and high fat diets for the study of atherosclerosis in the mouse
-
Nishina PM, Verstuyft J, Paigen B. Synthetic low and high fat diets for the study of atherosclerosis in the mouse. J Lipid Res 31: 859-869, 1990.
-
(1990)
J Lipid Res
, vol.31
, pp. 859-869
-
-
Nishina, P.M.1
Verstuyft, J.2
Paigen, B.3
-
137
-
-
33746210257
-
Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice
-
Oertelt S, Lian ZX, Cheng CM, Chuang YH, Padgett KA, He XS, Ridgway WM, Ansari AA, Coppel RL, Li MO, Flavell RA, Kronenberg M, Mackay IR, Gershwin ME. Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-beta receptor II dominant-negative mice. J Immunol 177: 1655-1660, 2006.
-
(2006)
J Immunol
, vol.177
, pp. 1655-1660
-
-
Oertelt, S.1
Lian, Z.X.2
Cheng, C.M.3
Chuang, Y.H.4
Padgett, K.A.5
He, X.S.6
Ridgway, W.M.7
Ansari, A.A.8
Coppel, R.L.9
Li, M.O.10
Flavell, R.A.11
Kronenberg, M.12
McKay, I.R.13
Gershwin, M.E.14
-
138
-
-
79952462806
-
A novel and comprehensive mouse model of human non-alcoholic steatohepatitis with the full range of dysmetabolic and histological abnormalities induced by gold thioglucose and a high-fat diet
-
Ogasawara M, Hirose A, Ono M, Aritake K, Nozaki Y, Takahashi M, Okamoto N, Sakamoto S, Iwasaki S, Asanuma T, Taniguchi T, Urade Y, Onishi S, Saibara T, Oben JA. A novel and comprehensive mouse model of human non-alcoholic steatohepatitis with the full range of dysmetabolic and histological abnormalities induced by gold thioglucose and a high-fat diet. Liver Int 31: 542-551, 2011.
-
(2011)
Liver Int
, vol.31
, pp. 542-551
-
-
Ogasawara, M.1
Hirose, A.2
Ono, M.3
Aritake, K.4
Nozaki, Y.5
Takahashi, M.6
Okamoto, N.7
Sakamoto, S.8
Iwasaki, S.9
Asanuma, T.10
Taniguchi, T.11
Urade, Y.12
Onishi, S.13
Saibara, T.14
Oben, J.A.15
-
139
-
-
33750070921
-
Exacerbation of dietary steatohepatitis and fibrosis in obese, diabetic KK-A(y) mice
-
Okumura K, Ikejima K, Kon K, Abe W, Yamashina S, Enomoto N, Takei Y, Sato N. Exacerbation of dietary steatohepatitis and fibrosis in obese, diabetic KK-A(y) mice. Hepatol Res 36: 217-228, 2006.
-
(2006)
Hepatol Res
, vol.36
, pp. 217-228
-
-
Okumura, K.1
Ikejima, K.2
Kon, K.3
Abe, W.4
Yamashina, S.5
Enomoto, N.6
Takei, Y.7
Sato, N.8
-
140
-
-
33846253661
-
Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis
-
Ota T, Takamura T, Kurita S, Matsuzawa N, Kita Y, Uno M, Akahori H, Misu H, Sakurai M, Zen Y, Nakanuma Y, Kaneko S. Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis. Gastroenterology 132: 282-293, 2007.
-
(2007)
Gastroenterology
, vol.132
, pp. 282-293
-
-
Ota, T.1
Takamura, T.2
Kurita, S.3
Matsuzawa, N.4
Kita, Y.5
Uno, M.6
Akahori, H.7
Misu, H.8
Sakurai, M.9
Zen, Y.10
Nakanuma, Y.11
Kaneko, S.12
-
141
-
-
0028799756
-
Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse
-
Oude Elferink RP, Ottenhoff R, van Wijland M, Smit JJ, Schinkel AH, Groen AK. Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse. J Clin Invest 95: 31-38, 1995.
-
(1995)
J Clin Invest
, vol.95
, pp. 31-38
-
-
Oude Elferink, R.P.1
Ottenhoff, R.2
van Wijland, M.3
Smit, J.J.4
Schinkel, A.H.5
Groen, A.K.6
-
142
-
-
0034954716
-
Transplantation of human hepatocytes into tolerized genetically immunocompetent rats
-
Ouyang EC, Wu CH, Walton C, Promrat K, Wu GY. Transplantation of human hepatocytes into tolerized genetically immunocompetent rats. World J Gastroenterol 7: 324-330, 2001.
-
(2001)
World J Gastroenterol
, vol.7
, pp. 324-330
-
-
Ouyang, E.C.1
Wu, C.H.2
Walton, C.3
Promrat, K.4
Wu, G.Y.5
-
143
-
-
43049170503
-
Fructose consumption as a risk factor for non-alcoholic fatty liver disease
-
Ouyang X, Cirillo P, Sautin Y, McCall S, Bruchette JL, Diehl AM, Johnson RJ, Abdelmalek MF. Fructose consumption as a risk factor for non-alcoholic fatty liver disease. J Hepatol 48: 993-999, 2008.
-
(2008)
J Hepatol
, vol.48
, pp. 993-999
-
-
Ouyang, X.1
Cirillo, P.2
Sautin, Y.3
McCall, S.4
Bruchette, J.L.5
Diehl, A.M.6
Johnson, R.J.7
Abdelmalek, M.F.8
-
144
-
-
0021858935
-
Rapid induction of cirrhosis by administration of carbon tetrachloride plus phospholipase D
-
Ozeki T, Funakoshi K, Iwaki K. Rapid induction of cirrhosis by administration of carbon tetrachloride plus phospholipase D. Br J Exp Pathol 66: 385-390, 1985.
-
(1985)
Br J Exp Pathol
, vol.66
, pp. 385-390
-
-
Ozeki, T.1
Funakoshi, K.2
Iwaki, K.3
-
145
-
-
77953986092
-
Differential expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in thioacetamide-induced chronic liver injury
-
Park SY, Shin HW, Lee KB, Lee MJ, Jang JJ. Differential expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in thioacetamide-induced chronic liver injury. J Korean Med Sci 25: 570-576, 2010.
-
(2010)
J Korean Med Sci
, vol.25
, pp. 570-576
-
-
Park, S.Y.1
Shin, H.W.2
Lee, K.B.3
Lee, M.J.4
Jang, J.J.5
-
147
-
-
60149090028
-
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
-
Ploss A, Evans MJ, Gaysinskaya VA, Panis M, You H, de Jong YP, Rice CM. Human occludin is a hepatitis C virus entry factor required for infection of mouse cells. Nature 457: 882-886, 2009.
-
(2009)
Nature
, vol.457
, pp. 882-886
-
-
Ploss, A.1
Evans, M.J.2
Gaysinskaya, V.A.3
Panis, M.4
You, H.5
de Jong, Y.P.6
Rice, C.M.7
-
148
-
-
0016435386
-
Hepatocarcinogenesis by diethylnitrosamine in rats fed high dietary levels of lipotropes
-
Poirier LA. Hepatocarcinogenesis by diethylnitrosamine in rats fed high dietary levels of lipotropes. J Natl Cancer Inst 54: 137-140, 1975.
-
(1975)
J Natl Cancer Inst
, vol.54
, pp. 137-140
-
-
Poirier, L.A.1
-
149
-
-
27744512904
-
-/- mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro-and antifibrogenic genes
-
-/- mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro-and antifibrogenic genes. J Hepatol 43: 1045-1054, 2005.
-
(2005)
J Hepatol
, vol.43
, pp. 1045-1054
-
-
Popov, Y.1
Patsenker, E.2
Fickert, P.3
Trauner, M.4
Schuppan, D.5
-
150
-
-
77249139206
-
Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis
-
Popov Y, Sverdlov DY, Bhaskar KR, Sharma AK, Millonig G, Patsenker E, Krahenbuhl S, Krahenbuhl L, Schuppan D. Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis. Am J Physiol Gastrointest Liver Physiol 298: G323-G334, 2010.
-
(2010)
Am J Physiol Gastrointest Liver Physiol
, vol.298
-
-
Popov, Y.1
Sverdlov, D.Y.2
Bhaskar, K.R.3
Sharma, A.K.4
Millonig, G.5
Patsenker, E.6
Krahenbuhl, S.7
Krahenbuhl, L.8
Schuppan, D.9
-
151
-
-
0015642211
-
Age-and sex-associated diethylnitrosamine dealkylation activity of the mouse liver and hepatocarcinogenesis
-
Rao KV, Vesselinovitch SD. Age-and sex-associated diethylnitrosamine dealkylation activity of the mouse liver and hepatocarcinogenesis. Cancer Res 33: 1625-1627, 1973.
-
(1973)
Cancer Res
, vol.33
, pp. 1625-1627
-
-
Rao, K.V.1
Vesselinovitch, S.D.2
-
152
-
-
0035658444
-
Nonalcoholic steatosis and steatohepatitis. III. Peroxisomal β-oxidation, PPARα, and steatohepatitis
-
Reddy JK. Nonalcoholic steatosis and steatohepatitis. III. Peroxisomal β-oxidation, PPARα, and steatohepatitis. Am J Physiol Gastrointest Liver Physiol 281: G1333-G1339, 2001.
-
(2001)
Am J Physiol Gastrointest Liver Physiol
, vol.281
-
-
Reddy, J.K.1
-
153
-
-
0028353410
-
Replacement of diseased mouse liver by hepatic cell transplantation
-
Rhim JA, Sandgren EP, Degen JL, Palmiter RD, Brinster RL. Replacement of diseased mouse liver by hepatic cell transplantation. Science 263: 1149-1152, 1994.
-
(1994)
Science
, vol.263
, pp. 1149-1152
-
-
Rhim, J.A.1
Sandgren, E.P.2
Degen, J.L.3
Palmiter, R.D.4
Brinster, R.L.5
-
154
-
-
33747763332
-
Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis
-
Rieger R, Leung PS, Jeddeloh MR, Kurth MJ, Nantz MH, Lam KS, Barsky D, Ansari AA, Coppel RL, Mackay IR, Gershwin ME. Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis. J Autoimmun 27: 7-16, 2006.
-
(2006)
J Autoimmun
, vol.27
, pp. 7-16
-
-
Rieger, R.1
Leung, P.S.2
Jeddeloh, M.R.3
Kurth, M.J.4
Nantz, M.H.5
Lam, K.S.6
Barsky, D.7
Ansari, A.A.8
Coppel, R.L.9
McKay, I.R.10
Gershwin, M.E.11
-
155
-
-
0346689994
-
The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance
-
Rinella ME, Green RM. The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance. J Hepatol 40: 47-51, 2004.
-
(2004)
J Hepatol
, vol.40
, pp. 47-51
-
-
Rinella, M.E.1
Green, R.M.2
-
156
-
-
0036862005
-
Effects of ethanol exposure on subsequent acquisition and extinction of ethanol self-administration and expression of alcohol-seeking behavior in adult alcohol-preferring (P) rats: I. Periadolescent exposure
-
Rodd-Henricks ZA, Bell RL, Kuc KA, Murphy JM, McBride WJ, Lumeng L, Li TK. Effects of ethanol exposure on subsequent acquisition and extinction of ethanol self-administration and expression of alcohol-seeking behavior in adult alcohol-preferring (P) rats: I. Periadolescent exposure. Alcohol Clin Exp Res 26: 1632-1641, 2002.
-
(2002)
Alcohol Clin Exp Res
, vol.26
, pp. 1632-1641
-
-
Rodd-Henricks, Z.A.1
Bell, R.L.2
Kuc, K.A.3
Murphy, J.M.4
McBride, W.J.5
Lumeng, L.6
Li, T.K.7
-
157
-
-
33847252938
-
Long term highly saturated fat diet does not induce NASH in Wistar rats
-
Romestaing C, Piquet MA, Bedu E, Rouleau V, Dautresme M, Hourmand-Ollivier I, Filippi C, Duchamp C, Sibille B. Long term highly saturated fat diet does not induce NASH in Wistar rats. Nutr Metab (Lond) 4: 4, 2007.
-
(2007)
Nutr Metab (Lond)
, vol.4
, pp. 4
-
-
Romestaing, C.1
Piquet, M.A.2
Bedu, E.3
Rouleau, V.4
Dautresme, M.5
Hourmand-Ollivier, I.6
Filippi, C.7
Duchamp, C.8
Sibille, B.9
-
158
-
-
1642516133
-
Mouse reporter strain for noninvasive bioluminescent imaging of cells that have undergone Cre-mediated recombination
-
Safran M, Kim WY, Kung AL, Horner JW, DePinho RA, Kaelin WG Jr. Mouse reporter strain for noninvasive bioluminescent imaging of cells that have undergone Cre-mediated recombination. Mol Imaging 2: 297-302, 2003.
-
(2003)
Mol Imaging
, vol.2
, pp. 297-302
-
-
Safran, M.1
Kim, W.Y.2
Kung, A.L.3
Horner, J.W.4
DePinho, R.A.5
Kaelin Jr., W.G.6
-
159
-
-
7044241291
-
Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: Role of short-form leptin receptors and osteopontin
-
Sahai A, Malladi P, Pan X, Paul R, Melin-Aldana H, Green RM, Whitington PF. Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin. Am J Physiol Gastrointest Liver Physiol 287: G1035-G1043, 2004.
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.287
-
-
Sahai, A.1
Malladi, P.2
Pan, X.3
Paul, R.4
Melin-Aldana, H.5
Green, R.M.6
Whitington, P.F.7
-
160
-
-
43049094474
-
Ae2a, b-deficient mice develop antimitochondrial antibodies and other features resembling primary biliary cirrhosis
-
Salas JT, Banales JM, Sarvide S, Recalde S, Ferrer A, Uriarte I, Oude Elferink RP, Prieto J, Medina JF. Ae2a, b-deficient mice develop antimitochondrial antibodies and other features resembling primary biliary cirrhosis. Gastroenterology 134: 1482-1493, 2008.
-
(2008)
Gastroenterology
, vol.134
, pp. 1482-1493
-
-
Salas, J.T.1
Banales, J.M.2
Sarvide, S.3
Recalde, S.4
Ferrer, A.5
Uriarte, I.6
Oude Elferink, R.P.7
Prieto, J.8
Medina, J.F.9
-
161
-
-
54949116520
-
Activation of hepatic stellate cells is associated with cytokine expression in thioacetamide-induced hepatic fibrosis in mice
-
Salguero Palacios R, Roderfeld M, Hemmann S, Rath T, Atanasova S, Tschuschner A, Gressner OA, Weiskirchen R, Graf J, Roeb E. Activation of hepatic stellate cells is associated with cytokine expression in thioacetamide-induced hepatic fibrosis in mice. Lab Invest 88: 1192-1203, 2008.
-
(2008)
Lab Invest
, vol.88
, pp. 1192-1203
-
-
Salguero Palacios, R.1
Roderfeld, M.2
Hemmann, S.3
Rath, T.4
Atanasova, S.5
Tschuschner, A.6
Gressner, O.A.7
Weiskirchen, R.8
Graf, J.9
Roeb, E.10
-
162
-
-
0025781894
-
Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene
-
Sandgren EP, Palmiter RD, Heckel JL, Daugherty CC, Brinster RL, Degen JL. Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene. Cell 66: 245-256, 1991.
-
(1991)
Cell
, vol.66
, pp. 245-256
-
-
Sandgren, E.P.1
Palmiter, R.D.2
Heckel, J.L.3
Daugherty, C.C.4
Brinster, R.L.5
Degen, J.L.6
-
163
-
-
77956572699
-
Natural killer cells target HCV core proteins during the innate immune response in HCV transgenic mice
-
Satoh K, Takahashi H, Matsuda C, Tanaka T, Miyasaka M, Zeniya M, Kohara M. Natural killer cells target HCV core proteins during the innate immune response in HCV transgenic mice. J Med Virol 82: 1545-1553, 2010.
-
(2010)
J Med Virol
, vol.82
, pp. 1545-1553
-
-
Satoh, K.1
Takahashi, H.2
Matsuda, C.3
Tanaka, T.4
Miyasaka, M.5
Zeniya, M.6
Kohara, M.7
-
164
-
-
77952562217
-
Animal models of non-alcoholic steatohepatitis: Of mice and man
-
Schattenberg JM, Galle PR. Animal models of non-alcoholic steatohepatitis: of mice and man. Dig Dis 28: 247-254, 2010.
-
(2010)
Dig Dis
, vol.28
, pp. 247-254
-
-
Schattenberg, J.M.1
Galle, P.R.2
-
165
-
-
19944432263
-
Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis
-
Schiffer E, Housset C, Cacheux W, Wendum D, Desbois-Mouthon C, Rey C, Clergue F, Poupon R, Barbu V, Rosmorduc O. Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis. Hepatology 41: 307-314, 2005.
-
(2005)
Hepatology
, vol.41
, pp. 307-314
-
-
Schiffer, E.1
Housset, C.2
Cacheux, W.3
Wendum, D.4
Desbois-Mouthon, C.5
Rey, C.6
Clergue, F.7
Poupon, R.8
Barbu, V.9
Rosmorduc, O.10
-
167
-
-
79958813517
-
Pathogenesis of alcohol-induced liver disease: Classical concepts and recent advances
-
Seth D, Haber PS, Syn WK, Diehl AM, Day CP. Pathogenesis of alcohol-induced liver disease: classical concepts and recent advances. J Gastroenterol Hepatol 26: 1089-1105, 2011.
-
(2011)
J Gastroenterol Hepatol
, vol.26
, pp. 1089-1105
-
-
Seth, D.1
Haber, P.S.2
Syn, W.K.3
Diehl, A.M.4
Day, C.P.5
-
168
-
-
33747875872
-
Hepatitis B virus infection: Epidemiology and vaccination
-
Shepard CW, Simard EP, Finelli L, Fiore AE, Bell BP. Hepatitis B virus infection: epidemiology and vaccination. Epidemiol Rev 28: 112-125, 2006.
-
(2006)
Epidemiol Rev
, vol.28
, pp. 112-125
-
-
Shepard, C.W.1
Simard, E.P.2
Finelli, L.3
Fiore, A.E.4
Bell, B.P.5
-
169
-
-
0026799402
-
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
-
Shull MM, Ormsby I, Kier AB, Pawlowski S, Diebold RJ, Yin M, Allen R, Sidman C, Proetzel G, Calvin D, Annunziata N, Doetschman T. Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 359: 693-699, 1992.
-
(1992)
Nature
, vol.359
, pp. 693-699
-
-
Shull, M.M.1
Ormsby, I.2
Kier, A.B.3
Pawlowski, S.4
Diebold, R.J.5
Yin, M.6
Allen, R.7
Sidman, C.8
Proetzel, G.9
Calvin, D.10
Annunziata, N.11
Doetschman, T.12
-
170
-
-
0027363563
-
Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
-
Smit JJ, Schinkel AH, Oude Elferink RP, Groen AK, Wagenaar E, van Deemter L, Mol CA, Ottenhoff R, van der Lugt NM, van Roon MA, van der Valk MA, Offerhaus GJ, Berns AJ, Borst P. Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease. Cell 75: 451-462, 1993.
-
(1993)
Cell
, vol.75
, pp. 451-462
-
-
Smit, J.J.1
Schinkel, A.H.2
Oude Elferink, R.P.3
Groen, A.K.4
Wagenaar, E.5
van Deemter, L.6
Mol, C.A.7
Ottenhoff, R.8
van der Lugt, N.M.9
van Roon, M.A.10
van der Valk, M.A.11
Offerhaus, G.J.12
Berns, A.J.13
Borst, P.14
-
171
-
-
0034864792
-
Long-term effects of alcohol drinking on cerebral glucose utilization in alcohol-preferring rats
-
Smith DG, Learn JE, McBride WJ, Lumeng L, Li TK, Murphy JM. Long-term effects of alcohol drinking on cerebral glucose utilization in alcohol-preferring rats. Pharmacol Biochem Behav 69: 543-553, 2001.
-
(2001)
Pharmacol Biochem Behav
, vol.69
, pp. 543-553
-
-
Smith, D.G.1
Learn, J.E.2
McBride, W.J.3
Lumeng, L.4
Li, T.K.5
Murphy, J.M.6
-
172
-
-
79957597421
-
Telaprevir: An NS3/4A protease inhibitor for the treatment of chronic hepatitis C
-
Smith LS, Nelson M, Naik S, Woten J. Telaprevir: an NS3/4A protease inhibitor for the treatment of chronic hepatitis C. Ann Pharmacother 45: 639-648, 2011.
-
(2011)
Ann Pharmacother
, vol.45
, pp. 639-648
-
-
Smith, L.S.1
Nelson, M.2
Naik, S.3
Woten, J.4
-
173
-
-
0035033218
-
Transfer of hepatitis B virus genome by adenovirus vectors into cultured cells and mice: Crossing the species barrier
-
Sprinzl MF, Oberwinkler H, Schaller H, Protzer U. Transfer of hepatitis B virus genome by adenovirus vectors into cultured cells and mice: crossing the species barrier. J Virol 75: 5108-5118, 2001.
-
(2001)
J Virol
, vol.75
, pp. 5108-5118
-
-
Sprinzl, M.F.1
Oberwinkler, H.2
Schaller, H.3
Protzer, U.4
-
174
-
-
70350075402
-
Toll-like receptor 4 is involved in the development of fructoseinduced hepatic steatosis in mice
-
Spruss A, Kanuri G, Wagnerberger S, Haub S, Bischoff SC, Bergheim I. Toll-like receptor 4 is involved in the development of fructoseinduced hepatic steatosis in mice. Hepatology 50: 1094-1104, 2009.
-
(2009)
Hepatology
, vol.50
, pp. 1094-1104
-
-
Spruss, A.1
Kanuri, G.2
Wagnerberger, S.3
Haub, S.4
Bischoff, S.C.5
Bergheim, I.6
-
176
-
-
79551600267
-
β-Adrenoceptor blockade in sclerosing cholangitis of Mdr2 knockout mice: Antifibrotic effects in a model of nonsinusoidal fibrosis
-
Strack I, Schulte S, Varnholt H, Schievenbusch S, Tox U, Wendland K, Steffen HM, Drebber U, Dienes HP, Odenthal M. β-Adrenoceptor blockade in sclerosing cholangitis of Mdr2 knockout mice: antifibrotic effects in a model of nonsinusoidal fibrosis. Lab Invest 91: 252-261, 2011.
-
(2011)
Lab Invest
, vol.91
, pp. 252-261
-
-
Strack, I.1
Schulte, S.2
Varnholt, H.3
Schievenbusch, S.4
Tox, U.5
Wendland, K.6
Steffen, H.M.7
Drebber, U.8
Dienes, H.P.9
Odenthal, M.10
-
177
-
-
19644375041
-
Steatohepatitis develops rapidly in transgenic mice overexpressing Abcb11 and fed a methioninecholine-deficient diet
-
Sundaram SS, Whitington PF, Green RM. Steatohepatitis develops rapidly in transgenic mice overexpressing Abcb11 and fed a methioninecholine-deficient diet. Am J Physiol Gastrointest Liver Physiol 288: G1321-G1327, 2005.
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.288
-
-
Sundaram, S.S.1
Whitington, P.F.2
Green, R.M.3
-
178
-
-
33748794808
-
A model of insulin resistance and nonalcoholic steatohepatitis in rats: Role of peroxisome proliferator-activated receptor-alpha and n-3 polyunsaturated fatty acid treatment on liver injury
-
Svegliati-Baroni G, Candelaresi C, Saccomanno S, Ferretti G, Bachetti T, Marzioni M, De Minicis S, Nobili L, Salzano R, Omenetti A, Pacetti D, Sigmund S, Benedetti A, Casini A. A model of insulin resistance and nonalcoholic steatohepatitis in rats: role of peroxisome proliferator-activated receptor-alpha and n-3 polyunsaturated fatty acid treatment on liver injury. Am J Pathol 169: 846-860, 2006.
-
(2006)
Am J Pathol
, vol.169
, pp. 846-860
-
-
Svegliati-Baroni, G.1
Candelaresi, C.2
Saccomanno, S.3
Ferretti, G.4
Bachetti, T.5
Marzioni, M.6
de Minicis, S.7
Nobili, L.8
Salzano, R.9
Omenetti, A.10
Pacetti, D.11
Sigmund, S.12
Benedetti, A.13
Casini, A.14
-
179
-
-
57349167340
-
Titration of hepatitis B virus infectivity in the sera of preacute and late acute phases of HBV infection: Transmission experiments to chimeric mice with human liver repopulated hepatocytes
-
Tabuchi A, Tanaka J, Katayama K, Mizui M, Matsukura H, Yugi H, Shimada T, Miyakawa Y, Yoshizawa H. Titration of hepatitis B virus infectivity in the sera of preacute and late acute phases of HBV infection: transmission experiments to chimeric mice with human liver repopulated hepatocytes. J Med Virol 80: 2064-2068, 2008.
-
(2008)
J Med Virol
, vol.80
, pp. 2064-2068
-
-
Tabuchi, A.1
Tanaka, J.2
Katayama, K.3
Mizui, M.4
Matsukura, H.5
Yugi, H.6
Shimada, T.7
Miyakawa, Y.8
Yoshizawa, H.9
-
180
-
-
0026333396
-
Effect of dietary fat on Ito cell activation by chronic ethanol intake. A long-term serial morphometric study on alcohol-fed and control rats
-
Takahashi H, Wong K, Jui L, Nanji AA, Mendenhall CS, French SW. Effect of dietary fat on Ito cell activation by chronic ethanol intake. A long-term serial morphometric study on alcohol-fed and control rats. Alcohol Clin Exp Res 15: 1060-1066, 1991.
-
(1991)
Alcohol Clin Exp Res
, vol.15
, pp. 1060-1066
-
-
Takahashi, H.1
Wong, K.2
Jui, L.3
Nanji, A.A.4
Mendenhall, C.S.5
French, S.W.6
-
181
-
-
84861738395
-
Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
-
Takahashi Y, Soejima Y, Fukusato T. Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. World J Gastroenterol 18: 2300-2308, 2012.
-
(2012)
World J Gastroenterol
, vol.18
, pp. 2300-2308
-
-
Takahashi, Y.1
Soejima, Y.2
Fukusato, T.3
-
182
-
-
5144232785
-
Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses
-
Takehara T, Tatsumi T, Suzuki T, Rucker EB 3rd, Hennighausen L, Jinushi M, Miyagi T, Kanazawa Y, Hayashi N. Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses. Gastroenterology 127: 1189-1197, 2004.
-
(2004)
Gastroenterology
, vol.127
, pp. 1189-1197
-
-
Takehara, T.1
Tatsumi, T.2
Suzuki, T.3
Rucker III, E.B.4
Hennighausen, L.5
Jinushi, M.6
Miyagi, T.7
Kanazawa, Y.8
Hayashi, N.9
-
183
-
-
44649156317
-
Characteristics of hepatitis B virus genotype G coinfected with genotype H in chimeric mice carrying human hepatocytes
-
Tanaka Y, Sanchez LV, Sugiyama M, Sakamoto T, Kurbanov F, Tatematsu K, Roman S, Takahashi S, Shirai T, Panduro A, Mizokami M. Characteristics of hepatitis B virus genotype G coinfected with genotype H in chimeric mice carrying human hepatocytes. Virology 376: 408-415, 2008.
-
(2008)
Virology
, vol.376
, pp. 408-415
-
-
Tanaka, Y.1
Sanchez, L.V.2
Sugiyama, M.3
Sakamoto, T.4
Kurbanov, F.5
Tatematsu, K.6
Roman, S.7
Takahashi, S.8
Shirai, T.9
Panduro, A.10
Mizokami, M.11
-
184
-
-
70349731726
-
A genetic variant of hepatitis B virus divergent from known human and ape genotypes isolated from a Japanese patient and provisionally assigned to new genotype J
-
Tatematsu K, Tanaka Y, Kurbanov F, Sugauchi F, Mano S, Maeshiro T, Nakayoshi T, Wakuta M, Miyakawa Y, Mizokami M. A genetic variant of hepatitis B virus divergent from known human and ape genotypes isolated from a Japanese patient and provisionally assigned to new genotype J. J Virol 83: 10538-10547, 2009.
-
(2009)
J Virol
, vol.83
, pp. 10538-10547
-
-
Tatematsu, K.1
Tanaka, Y.2
Kurbanov, F.3
Sugauchi, F.4
Mano, S.5
Maeshiro, T.6
Nakayoshi, T.7
Wakuta, M.8
Miyakawa, Y.9
Mizokami, M.10
-
185
-
-
4344574035
-
Near completely humanized liver in mice shows human-type metabolic responses to drugs
-
Tateno C, Yoshizane Y, Saito N, Kataoka M, Utoh R, Yamasaki C, Tachibana A, Soeno Y, Asahina K, Hino H, Asahara T, Yokoi T, Furukawa T, Yoshizato K. Near completely humanized liver in mice shows human-type metabolic responses to drugs. Am J Pathol 165: 901-912, 2004.
-
(2004)
Am J Pathol
, vol.165
, pp. 901-912
-
-
Tateno, C.1
Yoshizane, Y.2
Saito, N.3
Kataoka, M.4
Utoh, R.5
Yamasaki, C.6
Tachibana, A.7
Soeno, Y.8
Asahina, K.9
Hino, H.10
Asahara, T.11
Yokoi, T.12
Furukawa, T.13
Yoshizato, K.14
-
186
-
-
57349137214
-
Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent
-
Tetri LH, Basaranoglu M, Brunt EM, Yerian LM, Neuschwander-Tetri BA. Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent. Am J Physiol Gastrointest Liver Physiol 295: G987-G995, 2008.
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.295
-
-
Tetri, L.H.1
Basaranoglu, M.2
Brunt, E.M.3
Yerian, L.M.4
Neuschwander-Tetri, B.A.5
-
187
-
-
50549084857
-
Spontaneous hepatic fibrosis in transgenic mice overexpressing PDGF-A
-
Thieringer F, Maass T, Czochra P, Klopcic B, Conrad I, Friebe D, Schirmacher P, Lohse AW, Blessing M, Galle PR, Teufel A, Kanzler S. Spontaneous hepatic fibrosis in transgenic mice overexpressing PDGF-A. Gene 423: 23-28, 2008.
-
(2008)
Gene
, vol.423
, pp. 23-28
-
-
Thieringer, F.1
Maass, T.2
Czochra, P.3
Klopcic, B.4
Conrad, I.5
Friebe, D.6
Schirmacher, P.7
Lohse, A.W.8
Blessing, M.9
Galle, P.R.10
Teufel, A.11
Kanzler, S.12
-
188
-
-
0026643743
-
A T cell-dependent experimental liver injury in mice inducible by concanavalin A
-
Tiegs G, Hentschel J, Wendel A. A T cell-dependent experimental liver injury in mice inducible by concanavalin A. J Clin Invest 90: 196-203, 1992.
-
(1992)
J Clin Invest
, vol.90
, pp. 196-203
-
-
Tiegs, G.1
Hentschel, J.2
Wendel, A.3
-
189
-
-
55949085226
-
Lessons from the toxic bile concept for the pathogenesis and treatment of cholestatic liver diseases
-
Trauner M, Fickert P, Halilbasic E, Moustafa T. Lessons from the toxic bile concept for the pathogenesis and treatment of cholestatic liver diseases. Wien Med Wochenschr 158: 542-548, 2008.
-
(2008)
Wien Med Wochenschr
, vol.158
, pp. 542-548
-
-
Trauner, M.1
Fickert, P.2
Halilbasic, E.3
Moustafa, T.4
-
190
-
-
84859763033
-
Glucagon-like peptide-1 (GLP-1) receptor agonism improves metabolic, biochemical and histopathological indices of nonalcoholic steatohepatitis (NASH) in mice
-
Trevaskis JL, Griffin PS, Wittmer C, Neuschwander-Tetri BA, Brunt EM, Dolman CS, Erickson MR, Napora J, Parkes DG, Roth JD. Glucagon-like peptide-1 (GLP-1) receptor agonism improves metabolic, biochemical and histopathological indices of nonalcoholic steatohepatitis (NASH) in mice. Am J Physiol Gastrointest Liver Physiol 302: G762-G772, 2012.
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.302
-
-
Trevaskis, J.L.1
Griffin, P.S.2
Wittmer, C.3
Neuschwander-Tetri, B.A.4
Brunt, E.M.5
Dolman, C.S.6
Erickson, M.R.7
Napora, J.8
Parkes, D.G.9
Roth, J.D.10
-
191
-
-
30944468404
-
Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus
-
Tsuge M, Hiraga N, Takaishi H, Noguchi C, Oga H, Imamura M, Takahashi S, Iwao E, Fujimoto Y, Ochi H, Chayama K, Tateno C, Yoshizato K. Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus. Hepatology 42: 1046-1054, 2005.
-
(2005)
Hepatology
, vol.42
, pp. 1046-1054
-
-
Tsuge, M.1
Hiraga, N.2
Takaishi, H.3
Noguchi, C.4
Oga, H.5
Imamura, M.6
Takahashi, S.7
Iwao, E.8
Fujimoto, Y.9
Ochi, H.10
Chayama, K.11
Tateno, C.12
Yoshizato, K.13
-
192
-
-
0021923933
-
Severe and progressive steatosis and focal necrosis in rat liver induced by continuous intragastric infusion of ethanol and low fat diet
-
Tsukamoto H, French SW, Benson N, Delgado G, Rao GA, Larkin EC, Largman C. Severe and progressive steatosis and focal necrosis in rat liver induced by continuous intragastric infusion of ethanol and low fat diet. Hepatology 5: 224-232, 1985.
-
(1985)
Hepatology
, vol.5
, pp. 224-232
-
-
Tsukamoto, H.1
French, S.W.2
Benson, N.3
Delgado, G.4
Rao, G.A.5
Larkin, E.C.6
Largman, C.7
-
193
-
-
0025028967
-
Insights into the pathogenesis of alcoholic liver necrosis and fibrosis: Status report
-
Tsukamoto H, Gaal K, French SW. Insights into the pathogenesis of alcoholic liver necrosis and fibrosis: status report. Hepatology 12: 599-608, 1990.
-
(1990)
Hepatology
, vol.12
, pp. 599-608
-
-
Tsukamoto, H.1
Gaal, K.2
French, S.W.3
-
194
-
-
0029160569
-
Experimental liver cirrhosis induced by alcohol and iron
-
Tsukamoto H, Horne W, Kamimura S, Niemela O, Parkkila S, Yla-Herttuala S, Brittenham GM. Experimental liver cirrhosis induced by alcohol and iron. J Clin Invest 96: 620-630, 1995.
-
(1995)
J Clin Invest
, vol.96
, pp. 620-630
-
-
Tsukamoto, H.1
Horne, W.2
Kamimura, S.3
Niemela, O.4
Parkkila, S.5
Yla-Herttuala, S.6
Brittenham, G.M.7
-
197
-
-
0022510347
-
Ethanol-induced liver fibrosis in rats fed high fat diet
-
Tsukamoto H, Towner SJ, Ciofalo LM, French SW. Ethanol-induced liver fibrosis in rats fed high fat diet. Hepatology 6: 814-822, 1986.
-
(1986)
Hepatology
, vol.6
, pp. 814-822
-
-
Tsukamoto, H.1
Towner, S.J.2
Ciofalo, L.M.3
French, S.W.4
-
198
-
-
84867694043
-
Hepatitis C virus-related lymphomagenesis in a mouse model
-
Tsukiyama-Kohara K, Sekiguchi S, Kasama Y, Salem NE, Machida K, Kohara M. Hepatitis C virus-related lymphomagenesis in a mouse model. ISRN Hematol 2011: 167501, 2011.
-
(2011)
ISRN Hematol
, vol.2011
, pp. 167501
-
-
Tsukiyama-Kohara, K.1
Sekiguchi, S.2
Kasama, Y.3
Salem, N.E.4
McHida, K.5
Kohara, M.6
-
199
-
-
84874590808
-
Pathological features of new animal models for primary biliary cirrhosis
-
Tsuneyama K, Moritoki Y, Kikuchi K, Nakanuma Y. Pathological features of new animal models for primary biliary cirrhosis. Int J Hepatol 2012: 403954, 2011.
-
(2011)
Int J Hepatol
, vol.2012
, pp. 403954
-
-
Tsuneyama, K.1
Moritoki, Y.2
Kikuchi, K.3
Nakanuma, Y.4
-
200
-
-
33744533583
-
Development of humanized mice for the study of hepatitis C virus infection
-
Turrini P, Sasso R, Germoni S, Marcucci I, Celluci A, Di Marco A, Marra E, Paonessa G, Eutropi A, Laufer R, Migliaccio G, Padron J. Development of humanized mice for the study of hepatitis C virus infection. Transplant Proc 38: 1181-1184, 2006.
-
(2006)
Transplant Proc
, vol.38
, pp. 1181-1184
-
-
Turrini, P.1
Sasso, R.2
Germoni, S.3
Marcucci, I.4
Celluci, A.5
Di Marco, A.6
Marra, E.7
Paonessa, G.8
Eutropi, A.9
Laufer, R.10
Migliaccio, G.11
Padron, J.12
-
201
-
-
0038374866
-
Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis
-
Ueberham E, Low R, Ueberham U, Schonig K, Bujard H, Gebhardt R. Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis. Hepatology 37: 1067-1078, 2003.
-
(2003)
Hepatology
, vol.37
, pp. 1067-1078
-
-
Ueberham, E.1
Low, R.2
Ueberham, U.3
Schonig, K.4
Bujard, H.5
Gebhardt, R.6
-
202
-
-
84861777658
-
Mouse intragastric infusion (iG) model
-
Ueno A, Lazaro R, Wang PY, Higashiyama R, Machida K, Tsukamoto H. Mouse intragastric infusion (iG) model. Nat Protoc 7: 771-781, 2012.
-
(2012)
Nat Protoc
, vol.7
, pp. 771-781
-
-
Ueno, A.1
Lazaro, R.2
Wang, P.Y.3
Higashiyama, R.4
McHida, K.5
Tsukamoto, H.6
-
203
-
-
77951298649
-
Murine models of autoimmune cholangitis
-
Ueno Y, Ambrosini YM, Moritoki Y, Ridgway WM, Gershwin ME. Murine models of autoimmune cholangitis. Curr Opin Gastroenterol 26: 274-279, 2010.
-
(2010)
Curr Opin Gastroenterol
, vol.26
, pp. 274-279
-
-
Ueno, Y.1
Ambrosini, Y.M.2
Moritoki, Y.3
Ridgway, W.M.4
Gershwin, M.E.5
-
204
-
-
75349095571
-
The replication cycle of hepatitis B virus
-
Urban S, Schulze A, Dandri M, Petersen J. The replication cycle of hepatitis B virus. J Hepatol 52: 282-284, 2010.
-
(2010)
J Hepatol
, vol.52
, pp. 282-284
-
-
Urban, S.1
Schulze, A.2
Dandri, M.3
Petersen, J.4
-
205
-
-
0242290378
-
Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression
-
Vergnes L, Phan J, Strauss M, Tafuri S, Reue K. Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression. J Biol Chem 278: 42774-42784, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 42774-42784
-
-
Vergnes, L.1
Phan, J.2
Strauss, M.3
Tafuri, S.4
Reue, K.5
-
207
-
-
0034890409
-
Animal models for primary sclerosing cholangitis
-
Vierling JM. Animal models for primary sclerosing cholangitis. Best Pract Res Clin Gastroenterol 15: 591-610, 2001.
-
(2001)
Best Pract Res Clin Gastroenterol
, vol.15
, pp. 591-610
-
-
Vierling, J.M.1
-
208
-
-
84861716805
-
Strong antiviral activity of the new L-hydroxycytidine derivative, L-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice
-
Volz T, Lutgehetmann M, Allweiss L, Warlich M, Bierwolf J, Pollok JM, Petersen J, Matthes E, Dandri M. Strong antiviral activity of the new L-hydroxycytidine derivative, L-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice. Antivir Ther 17: 623-631, 2012.
-
(2012)
Antivir Ther
, vol.17
, pp. 623-631
-
-
Volz, T.1
Lutgehetmann, M.2
Allweiss, L.3
Warlich, M.4
Bierwolf, J.5
Pollok, J.M.6
Petersen, J.7
Matthes, E.8
Dandri, M.9
-
209
-
-
49649091998
-
Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease
-
Wakabayashi K, Lian ZX, Leung PS, Moritoki Y, Tsuneyama K, Kurth MJ, Lam KS, Yoshida K, Yang GX, Hibi T, Ansari AA, Ridgway WM, Coppel RL, Mackay IR, Gershwin ME. Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease. Hepatology 48: 531-540, 2008.
-
(2008)
Hepatology
, vol.48
, pp. 531-540
-
-
Wakabayashi, K.1
Lian, Z.X.2
Leung, P.S.3
Moritoki, Y.4
Tsuneyama, K.5
Kurth, M.J.6
Lam, K.S.7
Yoshida, K.8
Yang, G.X.9
Hibi, T.10
Ansari, A.A.11
Ridgway, W.M.12
Coppel, R.L.13
McKay, I.R.14
Gershwin, M.E.15
-
210
-
-
33751002069
-
-/-) mice and the development of primary biliary cirrhosis
-
-/-) mice and the development of primary biliary cirrhosis. Hepatology 44: 1240-1249, 2006.
-
(2006)
Hepatology
, vol.44
, pp. 1240-1249
-
-
Wakabayashi, K.1
Lian, Z.X.2
Moritoki, Y.3
Lan, R.Y.4
Tsuneyama, K.5
Chuang, Y.H.6
Yang, G.X.7
Ridgway, W.8
Ueno, Y.9
Ansari, A.A.10
Coppel, R.L.11
McKay, I.R.12
Gershwin, M.E.13
-
211
-
-
59249094523
-
Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization
-
Wakabayashi K, Yoshida K, Leung PS, Moritoki Y, Yang GX, Tsuneyama K, Lian ZX, Hibi T, Ansari AA, Wicker LS, Ridgway WM, Coppel RL, Mackay IR, Gershwin ME. Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization. Clin Exp Immunol 155: 577-586, 2009.
-
(2009)
Clin Exp Immunol
, vol.155
, pp. 577-586
-
-
Wakabayashi, K.1
Yoshida, K.2
Leung, P.S.3
Moritoki, Y.4
Yang, G.X.5
Tsuneyama, K.6
Lian, Z.X.7
Hibi, T.8
Ansari, A.A.9
Wicker, L.S.10
Ridgway, W.M.11
Coppel, R.L.12
McKay, I.R.13
Gershwin, M.E.14
-
212
-
-
0033799920
-
Possible role of cytotoxic T cells in acute liver injury in hepatitis C virus cDNA transgenic mice mediated by Cre/loxP system
-
Wakita T, Katsume A, Kato J, Taya C, Yonekawa H, Kanegae Y, Saito I, Hayashi Y, Koike M, Miyamoto M, Hiasa Y, Kohara M. Possible role of cytotoxic T cells in acute liver injury in hepatitis C virus cDNA transgenic mice mediated by Cre/loxP system. J Med Virol 62: 308-317, 2000.
-
(2000)
J Med Virol
, vol.62
, pp. 308-317
-
-
Wakita, T.1
Katsume, A.2
Kato, J.3
Taya, C.4
Yonekawa, H.5
Kanegae, Y.6
Saito, I.7
Hayashi, Y.8
Koike, M.9
Miyamoto, M.10
Hiasa, Y.11
Kohara, M.12
-
213
-
-
0032502731
-
Efficient conditional transgene expression in hepatitis C virus cDNA transgenic mice mediated by the Cre/loxP system
-
Wakita T, Taya C, Katsume A, Kato J, Yonekawa H, Kanegae Y, Saito I, Hayashi Y, Koike M, Kohara M. Efficient conditional transgene expression in hepatitis C virus cDNA transgenic mice mediated by the Cre/loxP system. J Biol Chem 273: 9001-9006, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 9001-9006
-
-
Wakita, T.1
Taya, C.2
Katsume, A.3
Kato, J.4
Yonekawa, H.5
Kanegae, Y.6
Saito, I.7
Hayashi, Y.8
Koike, M.9
Kohara, M.10
-
214
-
-
84862943893
-
Immune mechanisms of Concanavalin A model of autoimmune hepatitis
-
Wang HX, Liu M, Weng SY, Li JJ, Xie C, He HL, Guan W, Yuan YS, Gao J. Immune mechanisms of Concanavalin A model of autoimmune hepatitis. World J Gastroenterol 18: 119-125, 2012.
-
(2012)
World J Gastroenterol
, vol.18
, pp. 119-125
-
-
Wang, H.X.1
Liu, M.2
Weng, S.Y.3
Li, J.J.4
Xie, C.5
He, H.L.6
Guan, W.7
Yuan, Y.S.8
Gao, J.9
-
215
-
-
79953196869
-
A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease
-
Washburn ML, Bility MT, Zhang L, Kovalev GI, Buntzman A, Frelinger JA, Barry W, Ploss A, Rice CM, Su L. A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease. Gastroenterology 140: 1334-1344, 2011.
-
(2011)
Gastroenterology
, vol.140
, pp. 1334-1344
-
-
Washburn, M.L.1
Bility, M.T.2
Zhang, L.3
Kovalev, G.I.4
Buntzman, A.5
Frelinger, J.A.6
Barry, W.7
Ploss, A.8
Rice, C.M.9
Su, L.10
-
217
-
-
33947169352
-
Immunopathology of schistosomiasis
-
Wilson MS, Mentink-Kane MM, Pesce JT, Ramalingam TR, Thompson R, Wynn TA. Immunopathology of schistosomiasis. Immunol Cell Biol 85: 148-154, 2007.
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 148-154
-
-
Wilson, M.S.1
Mentink-Kane, M.M.2
Pesce, J.T.3
Ramalingam, T.R.4
Thompson, R.5
Wynn, T.A.6
-
218
-
-
49649110937
-
Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
-
Wouters K, van Gorp PJ, Bieghs V, Gijbels MJ, Duimel H, Lutjohann D, Kerksiek A, van Kruchten R, Maeda N, Staels B, van Bilsen M, Shiri-Sverdlov R, Hofker MH. Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis. Hepatology 48: 474-486, 2008.
-
(2008)
Hepatology
, vol.48
, pp. 474-486
-
-
Wouters, K.1
van Gorp, P.J.2
Bieghs, V.3
Gijbels, M.J.4
Duimel, H.5
Lutjohann, D.6
Kerksiek, A.7
van Kruchten, R.8
Maeda, N.9
Staels, B.10
van Bilsen, M.11
Shiri-Sverdlov, R.12
Hofker, M.H.13
-
219
-
-
19044395632
-
A novel immunocompetent rat model of HCV infection and hepatitis
-
Wu GY, Konishi M, Walton CM, Olive D, Hayashi K, Wu CH. A novel immunocompetent rat model of HCV infection and hepatitis. Gastroenterology 128: 1416-1423, 2005.
-
(2005)
Gastroenterology
, vol.128
, pp. 1416-1423
-
-
Wu, G.Y.1
Konishi, M.2
Walton, C.M.3
Olive, D.4
Hayashi, K.5
Wu, C.H.6
-
220
-
-
0029834440
-
Animal models of liver fibrosis
-
Wu J, Norton PA. Animal models of liver fibrosis. Scand J Gastroenterol 31: 1137-1143, 1996.
-
(1996)
Scand J Gastroenterol
, vol.31
, pp. 1137-1143
-
-
Wu, J.1
Norton, P.A.2
-
221
-
-
77950355485
-
Characterization of high-fat, diet-induced, non-alcoholic steatohepatitis with fibrosis in rats
-
Xu ZJ, Fan JG, Ding XD, Qiao L, Wang GL. Characterization of high-fat, diet-induced, non-alcoholic steatohepatitis with fibrosis in rats. Dig Dis Sci 55: 931-940, 2010.
-
(2010)
Dig Dis Sci
, vol.55
, pp. 931-940
-
-
Xu, Z.J.1
Fan, J.G.2
Ding, X.D.3
Qiao, L.4
Wang, G.L.5
-
222
-
-
0037108818
-
Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection
-
Yang PL, Althage A, Chung J, Chisari FV. Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection. Proc Natl Acad Sci USA 99: 13825-13830, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13825-13830
-
-
Yang, P.L.1
Althage, A.2
Chung, J.3
Chisari, F.V.4
-
223
-
-
84856449557
-
A novel murine model for non-alcoholic steatohepatitis developed by combination of a high-fat diet and oxidized low-density lipoprotein
-
Yimin, Furumaki H, Matsuoka S, Sakurai T, Kohanawa M, Zhao S, Kuge Y, Tamaki N, Chiba H. A novel murine model for non-alcoholic steatohepatitis developed by combination of a high-fat diet and oxidized low-density lipoprotein. Lab Invest 92: 265-281, 2011.
-
(2011)
Lab Invest
, vol.92
, pp. 265-281
-
-
Yimin1
Furumaki, H.2
Matsuoka, S.3
Sakurai, T.4
Kohanawa, M.5
Zhao, S.6
Kuge, Y.7
Tamaki, N.8
Chiba, H.9
-
224
-
-
0032835529
-
Essential role of tumor necrosis factor alpha in alcoholinduced liver injury in mice
-
Yin M, Wheeler MD, Kono H, Bradford BU, Gallucci RM, Luster MI, Thurman RG. Essential role of tumor necrosis factor alpha in alcoholinduced liver injury in mice. Gastroenterology 117: 942-952, 1999.
-
(1999)
Gastroenterology
, vol.117
, pp. 942-952
-
-
Yin, M.1
Wheeler, M.D.2
Kono, H.3
Bradford, B.U.4
Gallucci, R.M.5
Luster, M.I.6
Thurman, R.G.7
-
225
-
-
7944221186
-
The keratin cytoskeleton in liver diseases
-
Zatloukal K, Stumptner C, Fuchsbichler A, Fickert P, Lackner C, Trauner M, Denk H. The keratin cytoskeleton in liver diseases. J Pathol 204: 367-376, 2004.
-
(2004)
J Pathol
, vol.204
, pp. 367-376
-
-
Zatloukal, K.1
Stumptner, C.2
Fuchsbichler, A.3
Fickert, P.4
Lackner, C.5
Trauner, M.6
Denk, H.7
-
226
-
-
59149097207
-
Expert opinion on the treatment of patients with chronic hepatitis C
-
Zeuzem S, Berg T, Moeller B, Hinrichsen H, Mauss S, Wedemeyer H, Sarrazin C, Hueppe D, Zehnter E, Manns MP. Expert opinion on the treatment of patients with chronic hepatitis C. J Viral Hepat 16: 75-90, 2009.
-
(2009)
J Viral Hepat
, vol.16
, pp. 75-90
-
-
Zeuzem, S.1
Berg, T.2
Moeller, B.3
Hinrichsen, H.4
Mauss, S.5
Wedemeyer, H.6
Sarrazin, C.7
Hueppe, D.8
Zehnter, E.9
Manns, M.P.10
-
227
-
-
77955266159
-
Effects and regulation of autoreactive CD8+ T cells in a transgenic mouse model of autoimmune hepatitis
-
986.e1-3
-
Zierden M, Kuhnen E, Odenthal M, Dienes HP. Effects and regulation of autoreactive CD8+ T cells in a transgenic mouse model of autoimmune hepatitis. Gastroenterology 139: 975-986, 986. e1-3, 2010.
-
(2010)
Gastroenterology
, vol.139
, pp. 975-986
-
-
Zierden, M.1
Kuhnen, E.2
Odenthal, M.3
Dienes, H.P.4
-
228
-
-
0023616653
-
Biochemical and morphological studies on production and regression of experimental liver cirrhosis induced by thioacetamide in Uje:WIST rats
-
Zimmermann T, Müller A, Machnik G, Franke H, Schubert H, Dargel R. Biochemical and morphological studies on production and regression of experimental liver cirrhosis induced by thioacetamide in Uje:WIST rats. Z Versuchstierkd 30: 165-180, 1987.
-
(1987)
Z Versuchstierkd
, vol.30
, pp. 165-180
-
-
Zimmermann, T.1
Müller, A.2
McHnik, G.3
Franke, H.4
Schubert, H.5
Dargel, R.6
-
229
-
-
33746299139
-
High-fat emulsion-induced rat model of nonalcoholic steatohepatitis
-
Zou Y, Li J, Lu C, Wang J, Ge J, Huang Y, Zhang L, Wang Y. High-fat emulsion-induced rat model of nonalcoholic steatohepatitis. Life Sci 79: 1100-1107, 2006.
-
(2006)
Life Sci
, vol.79
, pp. 1100-1107
-
-
Zou, Y.1
Li, J.2
Lu, C.3
Wang, J.4
Ge, J.5
Huang, Y.6
Zhang, L.7
Wang, Y.8
|