Β-Adrenoceptor blockade in sclerosing cholangitis of Mdr2 knockout mice: Antifibrotic effects in a model of nonsinusoidal fibrosis

Laboratory Investigation

Volumn 91, Issue 2, 2011, Pages 252-261

  Strack, Ingo ^a   Schulte, Sigrid ^a   Varnholt, Heike ^a,b   Schievenbusch, Stephanie ^a   Töx, Ulrich ^a   Wendland, Katharina ^a   Steffen, Hans Michael ^a   Drebber, Uta ^a   Dienes, Hans Peter ^a   Odenthal, Margarete ^a  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Abcb4; fibroblasts; fibrosis; Mdr2; primary sclerosing cholangitis; propranolol; sympathetic nervous system

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; AMINOTRANSFERASE; ANTIFIBROTIC AGENT; BETA ADRENERGIC RECEPTOR; CONNECTIVE TISSUE GROWTH FACTOR; ENDOTHELIN 1; HYDROXYPROLINE; PROCOLLAGEN; PROCOLLAGEN 1A1; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG ACTIVITY; DRUG EFFECT; FIBROSIS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; NONSINUSOIDAL FIBROSIS; PRIORITY JOURNAL; SCLEROSING CHOLANGITIS;

EID: 79551600267     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2010.162     Document Type: Article

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