NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis

Journal of Experimental Medicine

Volumn 203, Issue 5, 2006, Pages 1209-1219

  Irie, Junichiro ^a   Wu, Yuehong ^a   Wicker, Linda S ^b   Rainbow, Daniel ^b   Nalesnik, Michael A ^a   Hirsch, Raphael ^c   Peterson, Laurence B ^d   Leung, Patrick S C ^e   Cheng, Chunmei ^e   Mackay, Ian R ^f   Gershwin, M Eric ^e   Ridgway, William M ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; BILIARY TRACT DISEASE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CELL TRANSFER; CHOLANGITIS; CHROMOSOME 4; CONGENIC STRAIN; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; EOSINOPHIL; GRANULOMA; LIVER HISTOLOGY; MOUSE; MOUSE STRAIN; NONHUMAN; PATHOGENESIS; PATHOGENICITY; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; SEROLOGY; SPLEEN CELL;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD3; AUTOANTIBODIES; AUTOIMMUNE DISEASES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHOLANGITIS; CHROMOSOME MAPPING; DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE; DISEASE MODELS, ANIMAL; GRANULOMA; HUMANS; INFLAMMATION; LIVER CIRRHOSIS, BILIARY; LIVER CIRRHOSIS, EXPERIMENTAL; MICE; MICE, CONGENIC; MICE, INBRED NOD; MICE, SCID; MICE, TRANSGENIC; MITOCHONDRIAL PROTEINS; PROTEIN STRUCTURE, TERTIARY; QUANTITATIVE TRAIT LOCI;

EID: 33646673596     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20051911     Document Type: Article

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