-
1
-
-
4744352571
-
Role of NK and NKT cells in the immunopathogenesis of HCV-induced hepatitis
-
Ahmad A, Alvarez F. 2004. Role of NK and NKT cells in the immunopathogenesis of HCV-induced hepatitis. J Leukoc Biol 76:743-759.
-
(2004)
J Leukoc Biol
, vol.76
, pp. 743-759
-
-
Ahmad, A.1
Alvarez, F.2
-
2
-
-
0034948009
-
DNA microarray analysis of chimpanzee liver during acute resolving hepatitis C virus infection
-
Bigger CB, Brasky KM, Lanford RE. 2001. DNA microarray analysis of chimpanzee liver during acute resolving hepatitis C virus infection. J Virol 75:7059-7066.
-
(2001)
J Virol
, vol.75
, pp. 7059-7066
-
-
Bigger, C.B.1
Brasky, K.M.2
Lanford, R.E.3
-
3
-
-
0034623816
-
Efficient initiation of HCV RNA replication in cell culture
-
Blight KJ, Kolykhalov AA, Rice CM. 2000. Efficient initiation of HCV RNA replication in cell culture. Science 290:1972-1974.
-
(2000)
Science
, vol.290
, pp. 1972-1974
-
-
Blight, K.J.1
Kolykhalov, A.A.2
Rice, C.M.3
-
4
-
-
0030973604
-
Transgenic mice expressing IFN-gamma in the epidermis have eczema, hair hypopigmentation, and hair loss
-
Carroll JM, Crompton T, Seery JP, Watt FM. 1997. Transgenic mice expressing IFN-gamma in the epidermis have eczema, hair hypopigmentation, and hair loss. J Invest Dermatol 108:412-422.
-
(1997)
J Invest Dermatol
, vol.108
, pp. 412-422
-
-
Carroll, J.M.1
Crompton, T.2
Seery, J.P.3
Watt, F.M.4
-
5
-
-
0037033359
-
Inhibition of natural killer cells through engagement of CD81 by the major hepatitis C virus envelope protein
-
Crotta S, Stilla A, Wack A, D'Andrea A, Nuti S, D'Oro U, Mosca M, Filliponi F, Brunetto RM, Bonino F, Abrignani S, Valiante NM. 2002. Inhibition of natural killer cells through engagement of CD81 by the major hepatitis C virus envelope protein. J Exp Med 195:35-41.
-
(2002)
J Exp Med
, vol.195
, pp. 35-41
-
-
Crotta, S.1
Stilla, A.2
Wack, A.3
D'Andrea, A.4
Nuti, S.5
D'Oro, U.6
Mosca, M.7
Filliponi, F.8
Brunetto, R.M.9
Bonino, F.10
Abrignani, S.11
Valiante, N.M.12
-
6
-
-
10744232784
-
Impaired clearance of virus-infected hepatocytes in transgenic mice expressing the hepatitis C virus polyprotein
-
Disson O, Haouzi D, Desagher S, Loesch K, Hahne M, Kremer EJ, Jacquet C, Lemon SM, Hibner U, Lerat H. Impaired clearance of virus-infected hepatocytes in transgenic mice expressing the hepatitis C virus polyprotein. Gastroenterology 2004. 126:859-872.
-
(2004)
Gastroenterology
, vol.126
, pp. 859-872
-
-
Disson, O.1
Haouzi, D.2
Desagher, S.3
Loesch, K.4
Hahne, M.5
Kremer, E.J.6
Jacquet, C.7
Lemon, S.M.8
Hibner, U.9
Lerat, H.10
-
7
-
-
7644226241
-
Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation
-
Dolganiuc A, Oak S, Kodys K, Golenbock DT, Finberg RW, Kurt-Jones E, Szabo G. 2004. Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation. Gastroenterology 127:1513-1524.
-
(2004)
Gastroenterology
, vol.127
, pp. 1513-1524
-
-
Dolganiuc, A.1
Oak, S.2
Kodys, K.3
Golenbock, D.T.4
Finberg, R.W.5
Kurt-Jones, E.6
Szabo, G.7
-
8
-
-
0029805028
-
The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo
-
Duncan GS, Mittrucker HW, Kagi D, Matsuyama T, Mak TW. 1996. The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo. J Exp Med 184:2043-2048.
-
(1996)
J Exp Med
, vol.184
, pp. 2043-2048
-
-
Duncan, G.S.1
Mittrucker, H.W.2
Kagi, D.3
Matsuyama, T.4
Mak, T.W.5
-
9
-
-
47149116458
-
Hepatitis C virus-infected hepatocytes extrinsically modulate dendritic cell maturation to activate T cells and natural killer cells
-
Ebihara T, Shingai M, Matsumoto M, Wakita T, Seya T. 2008. Hepatitis C virus-infected hepatocytes extrinsically modulate dendritic cell maturation to activate T cells and natural killer cells. Hepatology 48:48-58.
-
(2008)
Hepatology
, vol.48
, pp. 48-58
-
-
Ebihara, T.1
Shingai, M.2
Matsumoto, M.3
Wakita, T.4
Seya, T.5
-
10
-
-
0037290831
-
Natural killer cells and viral infections
-
French AR, Yokoyama WM. 2003. Natural killer cells and viral infections. Curr Opin Immunol 15:45-51.
-
(2003)
Curr Opin Immunol
, vol.15
, pp. 45-51
-
-
French, A.R.1
Yokoyama, W.M.2
-
11
-
-
0036191172
-
Interferon-gamma inhibits replication of subgenomic and genomic hepatitis C virus RNAs
-
Frese M, Schwarzle V, Barth K, Krieger N, Lohmann V, Mihm S, Haller O, Bartenschlager R. 2002. Interferon-gamma inhibits replication of subgenomic and genomic hepatitis C virus RNAs. Hepatology 35:694-703.
-
(2002)
Hepatology
, vol.35
, pp. 694-703
-
-
Frese, M.1
Schwarzle, V.2
Barth, K.3
Krieger, N.4
Lohmann, V.5
Mihm, S.6
Haller, O.7
Bartenschlager, R.8
-
12
-
-
0038575483
-
Acute hepatitis C: High rate of both spontaneous and treatment-induced viral clearance
-
Gerlach JT, Diepolder HM, Zachoval R, Gruener NH, Jung MC, Ulsenheimer A, Schraut WW, Schrirren CA, Waechtler M, Backmund M, Pape GR. 2003. Acute hepatitis C: High rate of both spontaneous and treatment-induced viral clearance. Gastroenterology 125:80-88.
-
(2003)
Gastroenterology
, vol.125
, pp. 80-88
-
-
Gerlach, J.T.1
Diepolder, H.M.2
Zachoval, R.3
Gruener, N.H.4
Jung, M.C.5
Ulsenheimer, A.6
Schraut, W.W.7
Schrirren, C.A.8
Waechtler, M.9
Backmund, M.10
Pape, G.R.11
-
13
-
-
48249137638
-
Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure
-
Golden-Mason L, Madrigal-Estebas L, McGrath E, Conroy MJ, Ryan EJ, Hegarty JE, O'Farrelly C, Doherty DG. 2008. Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure. Gut 57:1121-1128.
-
(2008)
Gut
, vol.57
, pp. 1121-1128
-
-
Golden-Mason, L.1
Madrigal-Estebas, L.2
McGrath, E.3
Conroy, M.J.4
Ryan, E.J.5
Hegarty, J.E.6
O'Farrelly, C.7
Doherty, D.G.8
-
14
-
-
33645297935
-
Natural killer cells: Primary target for hepatitis C virus immune evasion strategies?
-
Golden-Mason L, Rosen HR. 2006. Natural killer cells: Primary target for hepatitis C virus immune evasion strategies? Liver Transpl 12:363-372.
-
(2006)
Liver Transpl
, vol.12
, pp. 363-372
-
-
Golden-Mason, L.1
Rosen, H.R.2
-
15
-
-
57449102983
-
Hepatitis C virus (HCV): A review of immunological aspects
-
Irshad M, Khushboo I, Singh S, Singh S. 2008. Hepatitis C virus (HCV): A review of immunological aspects. Int Rev Immunol 27:497-517.
-
(2008)
Int Rev Immunol
, vol.27
, pp. 497-517
-
-
Irshad, M.1
Khushboo, I.2
Singh, S.3
Singh, S.4
-
16
-
-
17644439750
-
Detection of hepatitis C virus specific core protein in serum of patients by a sensitive fluorescence enzyme immunoassay (FEIA)
-
Kashiwakuma T, Hasegawa A, Kajita T, Takata A, Mori H, Ohta Y, Tanaka E, Kiyosawa K, Tanaka T, Tanaka S, Hattori N, Kohara M. 1996. Detection of hepatitis C virus specific core protein in serum of patients by a sensitive fluorescence enzyme immunoassay (FEIA). J Immunol Methods 190:79-89.
-
(1996)
J Immunol Methods
, vol.190
, pp. 79-89
-
-
Kashiwakuma, T.1
Hasegawa, A.2
Kajita, T.3
Takata, A.4
Mori, H.5
Ohta, Y.6
Tanaka, E.7
Kiyosawa, K.8
Tanaka, T.9
Tanaka, S.10
Hattori, N.11
Kohara, M.12
-
17
-
-
77955471594
-
Consistent beneficial effects of killer cell immunoglobulin-like receptor 2DL3 and group 1 human leukocyte antigen-C following exposure to hepatitis C virus
-
Knapp S, Warshow U, Hegazy D, Brackbury L, Guha IN, Fowell A, Little AM, Alexander GJ, Rosenberg WM, Cramp ME, Khakoo SI. 2009. Consistent beneficial effects of killer cell immunoglobulin-like receptor 2DL3 and group 1 human leukocyte antigen-C following exposure to hepatitis C virus. Hepatology 51:1-8.
-
(2009)
Hepatology
, vol.51
, pp. 1-8
-
-
Knapp, S.1
Warshow, U.2
Hegazy, D.3
Brackbury, L.4
Guha, I.N.5
Fowell, A.6
Little, A.M.7
Alexander, G.J.8
Rosenberg, W.M.9
Cramp, M.E.10
Khakoo, S.I.11
-
18
-
-
0037228023
-
Antiviral effect and virus-host interactions in response to alpha interferon, gamma interferon, poly(i)-poly(c), tumor necrosis factor alpha, and ribavirin in hepatitis C virus subgenomic replicons
-
Lanford RE, Guerra B, Lee H, Averett DR, Pfeiffer B, Chavez D, Notvall L, Bigger C. 2003. Antiviral effect and virus-host interactions in response to alpha interferon, gamma interferon, poly(i)-poly(c), tumor necrosis factor alpha, and ribavirin in hepatitis C virus subgenomic replicons. J Virol 77:1092-1104.
-
(2003)
J Virol
, vol.77
, pp. 1092-1104
-
-
Lanford, R.E.1
Guerra, B.2
Lee, H.3
Averett, D.R.4
Pfeiffer, B.5
Chavez, D.6
Notvall, L.7
Bigger, C.8
-
19
-
-
0032805251
-
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
-
Liu F, Song Y, Liu D. 1999. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther 6:1258-1266.
-
(1999)
Gene Ther
, vol.6
, pp. 1258-1266
-
-
Liu, F.1
Song, Y.2
Liu, D.3
-
20
-
-
0345188811
-
Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line
-
Lohmann V, Korner F, Koch J, Herian U, Theilmann L, Bartenschlager R. 1999. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 285:110-113.
-
(1999)
Science
, vol.285
, pp. 110-113
-
-
Lohmann, V.1
Korner, F.2
Koch, J.3
Herian, U.4
Theilmann, L.5
Bartenschlager, R.6
-
21
-
-
0035853773
-
Inhibition of cytochrome c release in Fas-mediated signaling pathway in transgenic mice induced to express hepatitis C viral proteins
-
Machida K, Tsukiyama-Kohara K, Seike E, Tone S, Shibasaki F, Shimizu M, Takahashi H, Funata N, Taya C, Yonekawa H, Kohara M. 2001. Inhibition of cytochrome c release in Fas-mediated signaling pathway in transgenic mice induced to express hepatitis C viral proteins. J Biol Chem 276:12140-12146.
-
(2001)
J Biol Chem
, vol.276
, pp. 12140-12146
-
-
Machida, K.1
Tsukiyama-Kohara, K.2
Seike, E.3
Tone, S.4
Shibasaki, F.5
Shimizu, M.6
Takahashi, H.7
Funata, N.8
Taya, C.9
Yonekawa, H.10
Kohara, M.11
-
22
-
-
0036284899
-
Previously infected and recovered chimpanzees exhibit rapid responses that control hepatitis C virus replication upon rechallenge
-
Major ME, Mihalik K, Puig M, Rehermann B, Nascimbeni M, Rice CM, Feinstone SM. 2002. Previously infected and recovered chimpanzees exhibit rapid responses that control hepatitis C virus replication upon rechallenge. J Virol 76:6586-6595.
-
(2002)
J Virol
, vol.76
, pp. 6586-6595
-
-
Major, M.E.1
Mihalik, K.2
Puig, M.3
Rehermann, B.4
Nascimbeni, M.5
Rice, C.M.6
Feinstone, S.M.7
-
23
-
-
0027361463
-
Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development
-
Matsuyama T, Kimura T, Kitagawa M, Pfeffer K, Kawakami T, Watanabe N, Kundig TM, Amakawa R, Kishihara K, Wakeham A. 1993. Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Cell 75:83-97.
-
(1993)
Cell
, vol.75
, pp. 83-97
-
-
Matsuyama, T.1
Kimura, T.2
Kitagawa, M.3
Pfeffer, K.4
Kawakami, T.5
Watanabe, N.6
Kundig, T.M.7
Amakawa, R.8
Kishihara, K.9
Wakeham, A.10
-
24
-
-
3242733298
-
Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo
-
Minakuchi Y, Takeshita F, Kosaka N, Sasaki H, Yamamoto Y, Kouno M, Honma K, Nagahara S, Hanai K, Sano A, Kato T, Terada M, Ochiya T. 2004. Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo. Nucleic Acids Res 32:e109.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Minakuchi, Y.1
Takeshita, F.2
Kosaka, N.3
Sasaki, H.4
Yamamoto, Y.5
Kouno, M.6
Honma, K.7
Nagahara, S.8
Hanai, K.9
Sano, A.10
Kato, T.11
Terada, M.12
Ochiya, T.13
-
25
-
-
0035342311
-
Biomaterials for gene delivery: Atelocollagen-mediated controlled release of molecular medicines
-
Ochiya T, Nagahara S, Sano A, Itoh H, Terada M. 2001. Biomaterials for gene delivery: Atelocollagen-mediated controlled release of molecular medicines. Curr Gene Ther 1:31-52.
-
(2001)
Curr Gene Ther
, vol.1
, pp. 31-52
-
-
Ochiya, T.1
Nagahara, S.2
Sano, A.3
Itoh, H.4
Terada, M.5
-
26
-
-
0032536787
-
The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cells
-
Ohteki T, Yoshida H, Matsuyama T, Duncan GS, Mak TW, Ohashi PS. 1998. The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cells. J Exp Med 187:967-972.
-
(1998)
J Exp Med
, vol.187
, pp. 967-972
-
-
Ohteki, T.1
Yoshida, H.2
Matsuyama, T.3
Duncan, G.S.4
Mak, T.W.5
Ohashi, P.S.6
-
27
-
-
0037180553
-
Genomic analysis of the host response to hepatitis C virus infection
-
Su AI, Pezacki JP, Wodicka L, Brideau AD, Supekova L, Thimme R, Wieland S, Jens B, Purcell RH, Schultz PG, Chisari FV. 2002. Genomic analysis of the host response to hepatitis C virus infection. Proc Natl Acad Sci USA 99:15669-15674.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15669-15674
-
-
Su, A.I.1
Pezacki, J.P.2
Wodicka, L.3
Brideau, A.D.4
Supekova, L.5
Thimme, R.6
Wieland, S.7
Jens, B.8
Purcell, R.H.9
Schultz, P.G.10
Chisari, F.V.11
-
28
-
-
0037423722
-
Induction of hepatic injury by hepatitis C virus-specific CD8+ murine cytotoxic T lymphocytes in transgenic mice expressing the viral structural genes
-
Takaku S, Nakagawa Y, Shimizu M, Norose Y, Maruyama I, Wakita T, Takano T, Kohara M, Takahashi H. 2003. Induction of hepatic injury by hepatitis C virus-specific CD8+ murine cytotoxic T lymphocytes in transgenic mice expressing the viral structural genes. Biochem Biophys Res Commun 301:330-337.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 330-337
-
-
Takaku, S.1
Nakagawa, Y.2
Shimizu, M.3
Norose, Y.4
Maruyama, I.5
Wakita, T.6
Takano, T.7
Kohara, M.8
Takahashi, H.9
-
29
-
-
0027237666
-
Selective long-term elimination of natural killer cells in vivo by an anti-interleukin 2 receptor beta chain monoclonal antibody in mice
-
Tanaka T, Kitamura F, Nagasaka Y, Kuida K, Suwa H, Miyasaka M. 1993. Selective long-term elimination of natural killer cells in vivo by an anti-interleukin 2 receptor beta chain monoclonal antibody in mice. J Exp Med 178:1103-1107.
-
(1993)
J Exp Med
, vol.178
, pp. 1103-1107
-
-
Tanaka, T.1
Kitamura, F.2
Nagasaka, Y.3
Kuida, K.4
Suwa, H.5
Miyasaka, M.6
-
30
-
-
0035914925
-
Determinants of viral clearance and persistence during acute hepatitis C virus infection
-
Thimme R, Oldach D, Chang KM, Steiger C, Ray SC, Chisari FV. 2001. Determinants of viral clearance and persistence during acute hepatitis C virus infection. J Exp Med 194:1395-1406.
-
(2001)
J Exp Med
, vol.194
, pp. 1395-1406
-
-
Thimme, R.1
Oldach, D.2
Chang, K.M.3
Steiger, C.4
Ray, S.C.5
Chisari, F.V.6
-
31
-
-
0037180506
-
Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease
-
Thimme R, Bukh J, Spangenberg HC, Wieland S, Pemberton J, Steiger C, Govindarajan S, Purcell RH, Chisari FV. 2002. Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease. Proc Natl Acad Sci USA 99:15661-15668.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15661-15668
-
-
Thimme, R.1
Bukh, J.2
Spangenberg, H.C.3
Wieland, S.4
Pemberton, J.5
Steiger, C.6
Govindarajan, S.7
Purcell, R.H.8
Chisari, F.V.9
-
32
-
-
0037033363
-
Binding of the hepatitis C virus envelope protein E2 to CD81 inhibits natural killer cell functions
-
Tseng CT, Klimpel GR. 2002. Binding of the hepatitis C virus envelope protein E2 to CD81 inhibits natural killer cell functions. J Exp Med 195:43-49.
-
(2002)
J Exp Med
, vol.195
, pp. 43-49
-
-
Tseng, C.T.1
Klimpel, G.R.2
-
33
-
-
2442514139
-
Activation of the CKI-CDK-Rb-E2F pathway in full genome hepatitis C virus-expressing cells
-
Tsukiyama-Kohara K, Tone S, Maruyama I, Inoue K, Katsume A, Nuriya H, Ohmori H, Ohkawa J, Taira K, Hoshikawa Y, Shibasaki F, Reth M, Minatogawa Y, Kohara M. 2004. Activation of the CKI-CDK-Rb-E2F pathway in full genome hepatitis C virus-expressing cells. J Biol Chem 279:14531-14541.
-
(2004)
J Biol Chem
, vol.279
, pp. 14531-14541
-
-
Tsukiyama-Kohara, K.1
Tone, S.2
Maruyama, I.3
Inoue, K.4
Katsume, A.5
Nuriya, H.6
Ohmori, H.7
Ohkawa, J.8
Taira, K.9
Hoshikawa, Y.10
Shibasaki, F.11
Reth, M.12
Minatogawa, Y.13
Kohara, M.14
-
34
-
-
72849120234
-
Effect of killer immunogloblin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection
-
Vidal-Castineira JR, Lopez ZA, Diaz PR, Alonso AR, Martinez BJ, Perez R, Fernandez SJ, Melon S, Prieto J, Rodrigo L, López LC. 2010. Effect of killer immunogloblin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection. J Virol 84: 475-481.
-
(2010)
J Virol
, vol.84
, pp. 475-481
-
-
Vidal-Castineira, J.R.1
Lopez, Z.A.2
Diaz, P.R.3
Alonso, A.R.4
Martinez, B.J.5
Perez, R.6
Fernandez, S.J.7
Melon, S.8
Prieto, J.9
Rodrigo, L.10
López, L.C.11
-
35
-
-
33845775795
-
The protein kinase IKKepsilon can inhibit HCV expression independently of IFN and its own expression is downregulated in HCV-infected livers
-
Vilasco M, Larrea E, Vitour D, Dabo S, Breiman A, Reqnault B, Riezu JI, Eid P, Prieto J, Meurs EF. 2006. The protein kinase IKKepsilon can inhibit HCV expression independently of IFN and its own expression is downregulated in HCV-infected livers. Hepatology 44:1635-1647.
-
(2006)
Hepatology
, vol.44
, pp. 1635-1647
-
-
Vilasco, M.1
Larrea, E.2
Vitour, D.3
Dabo, S.4
Breiman, A.5
Reqnault, B.6
Riezu, J.I.7
Eid, P.8
Prieto, J.9
Meurs, E.F.10
-
36
-
-
0032502731
-
Efficient conditional transgene expression in hepatitis C virus cDNA transgenic mice mediated by the Cre/loxP system
-
Wakita T, Taya C, Katsume A, Kato J, Yonekawa H, Kanegae Y, Saito I, Hayashi Y, Koike M, Kohara M. 1998. Efficient conditional transgene expression in hepatitis C virus cDNA transgenic mice mediated by the Cre/loxP system. J Biol Chem 273:9001-9006.
-
(1998)
J Biol Chem
, vol.273
, pp. 9001-9006
-
-
Wakita, T.1
Taya, C.2
Katsume, A.3
Kato, J.4
Yonekawa, H.5
Kanegae, Y.6
Saito, I.7
Hayashi, Y.8
Koike, M.9
Kohara, M.10
-
37
-
-
58949091314
-
Natural killer cell function is intact after direct exposure to infectious hepatitis C virions
-
Yoon JC, Shiina M, Ahlenstiel G, Rehermann B. 2008. Natural killer cell function is intact after direct exposure to infectious hepatitis C virions. Hepatology 49:12-21.
-
(2008)
Hepatology
, vol.49
, pp. 12-21
-
-
Yoon, J.C.1
Shiina, M.2
Ahlenstiel, G.3
Rehermann, B.4
|