Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection

Journal of Experimental Medicine

Volumn 205, Issue 6, 2008, Pages 1409-1422

  Holdener, Martin ^a   Hintermann, Edith ^a   Bayer, Monika ^a   Rhode, Antje ^b   Rodrigo, Evelyn ^b   Hintereder, Gudrun ^a   Johnson, Eric F ^c   Gonzalez, Frank J ^d   Pfeilschifter, Josef ^a   Manns, Michael P ^e   Herrath, Matthias Von G ^b   Christen, Urs ^a  

^a GOETHE UNIVERSITY   (Germany)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CYTOCHROME P450 2D6; EPITOPE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE HEPATITIS; CELL INFILTRATION; CONTROLLED STUDY; HUMAN ADENOVIRUS 5; IMMUNOLOGICAL TOLERANCE; LIVER FIBROSIS; LIVER INJURY; LIVER NECROSIS; MOUSE; NONHUMAN; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; VIRUS INFECTION; WILD TYPE;

ADENOVIRIDAE; ADENOVIRIDAE INFECTIONS; ANIMALS; AUTOANTIGENS; CYTOCHROME P-450 CYP2D6; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNE TOLERANCE; LIVER; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC;

EID: 45149109642     PISSN: 00221007     EISSN: 00221007     Source Type: Journal    
DOI: 10.1084/jem.20071859     Document Type: Article

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