-
1
-
-
0035082455
-
Peroxisomal β-oxidation and steatohepatitis
-
Rao MS, Reddy JK. Peroxisomal β-oxidation and steatohepatitis. Sem Liver Dis 2001;21:43-54.
-
(2001)
Sem Liver Dis
, vol.21
, pp. 43-54
-
-
Rao, M.S.1
Reddy, J.K.2
-
2
-
-
0032489437
-
Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor α (PPARα)
-
Aoyama T, Peters JM, Iritani N, et al. Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor α (PPARα). J Biol Chem 1998;273:5678-84.
-
(1998)
J Biol Chem
, vol.273
, pp. 5678-5684
-
-
Aoyama, T.1
Peters, J.M.2
Iritani, N.3
-
3
-
-
0034678013
-
Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis
-
Yeldandi AV, Rao MS, Reddy JK. Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis. Mut Res 2000;448:159-77.
-
(2000)
Mut Res
, vol.448
, pp. 159-177
-
-
Yeldandi, A.V.1
Rao, M.S.2
Reddy, J.K.3
-
4
-
-
0028355391
-
Peroxisome proliferator-activated receptors. Finding the orphan a home
-
Green S, Wahli W. Peroxisome proliferator-activated receptors. Finding the orphan a home. Mol Cell Endocrinol 1994;100:149-53.
-
(1994)
Mol Cell Endocrinol
, vol.100
, pp. 149-153
-
-
Green, S.1
Wahli, W.2
-
5
-
-
8044260810
-
PPAR tissue distribution and interactions with other hormone-signaling pathways
-
Lemberger T, Braissant O, Juge-Aubry C, et al. PPAR tissue distribution and interactions with other hormone-signaling pathways. Ann NY Acad Sci 1996:231-51.
-
(1996)
Ann NY Acad Sci
, pp. 231-251
-
-
Lemberger, T.1
Braissant, O.2
Juge-Aubry, C.3
-
6
-
-
0021051308
-
Carcinogenesis by hepatic peroxisome proliferators: Evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans
-
Reddy JK, Lalwani ND. Carcinogenesis by hepatic peroxisome proliferators: evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans. CRC Crit Rev Toxicol 1983;12:1-58.
-
(1983)
CRC Crit Rev Toxicol
, vol.12
, pp. 1-58
-
-
Reddy, J.K.1
Lalwani, N.D.2
-
7
-
-
0019824670
-
Review of the hepatic response to hypolipidemic drugs in rodents and assessment of its toxicological significance to man
-
Cohen AJ, Grasso P. Review of the hepatic response to hypolipidemic drugs in rodents and assessment of its toxicological significance to man. Fd Cosmet Toxicol 1981;19:585-605.
-
(1981)
Fd Cosmet Toxicol
, vol.19
, pp. 585-605
-
-
Cohen, A.J.1
Grasso, P.2
-
8
-
-
0141828972
-
Peroxisome proliferator-activated receptors, fatty acid oxidation, steatohepatitis and hepatocarcinogenesis
-
Yu S, Rao MS, Reddy JK. Peroxisome proliferator-activated receptors, fatty acid oxidation, steatohepatitis and hepatocarcinogenesis. Cur Mol Med 2003;3:561-72.
-
(2003)
Cur Mol Med
, vol.3
, pp. 561-572
-
-
Yu, S.1
Rao, M.S.2
Reddy, J.K.3
-
9
-
-
0028997684
-
Targeted disruption of the α isoform of the peroxisome proliferation-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
-
Lee SS, Pineau T, Drago J, et al. Targeted disruption of the α isoform of the peroxisome proliferation-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol 1995;15:3012-22.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3012-3022
-
-
Lee, S.S.1
Pineau, T.2
Drago, J.3
-
10
-
-
0034666132
-
Defect in peroxisome proliferator-activated receptor α-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting
-
Hashimoto T, Cook WS, Qi C, Yeldandi AV, Reddy JK, Rao MS. Defect in peroxisome proliferator-activated receptor α-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting. J Biol Chem 2000;275:28918-28.
-
(2000)
J Biol Chem
, vol.275
, pp. 28918-28928
-
-
Hashimoto, T.1
Cook, W.S.2
Qi, C.3
Yeldandi, A.V.4
Reddy, J.K.5
Rao, M.S.6
-
11
-
-
0032699670
-
Peroxisome proliferator-activated receptor α mediates the adaptive response to fasting
-
Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli W. Peroxisome proliferator-activated receptor α mediates the adaptive response to fasting. J Clin Invest 1999;103:1489-98.
-
(1999)
J Clin Invest
, vol.103
, pp. 1489-1498
-
-
Kersten, S.1
Seydoux, J.2
Peters, J.M.3
Gonzalez, F.J.4
Desvergne, B.5
Wahli, W.6
-
12
-
-
0031418657
-
Role of PPARα in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14, 643
-
Peters JM, Cattley RC, Gonzalez FJ. Role of PPARα in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14, 643. Carcinogenesis 1997;18:2029-33.
-
(1997)
Carcinogenesis
, vol.18
, pp. 2029-2033
-
-
Peters, J.M.1
Cattley, R.C.2
Gonzalez, F.J.3
-
13
-
-
0003101832
-
Biochemical aspects of fatty liver
-
Meeks RG, Harrison SD, Bull RJ, editors. Boca Raton: CRC Press
-
Dianzani MU. Biochemical aspects of fatty liver. In: Meeks RG, Harrison SD, Bull RJ, editors. Hepatotoxicology. Boca Raton: CRC Press; 1991. p. 327-99.
-
(1991)
Hepatotoxicology
, pp. 327-399
-
-
Dianzani, M.U.1
-
14
-
-
0031799747
-
Hepatic steatosis: Innocent bystander or guilty party?
-
Day CP, James OFW. Hepatic steatosis: innocent bystander or guilty party? Hepatology 1998;27:1463-5.
-
(1998)
Hepatology
, vol.27
, pp. 1463-1465
-
-
Day, C.P.1
James, O.F.W.2
-
15
-
-
0031761559
-
Diagnosis and interpretation of steatosis and steatohepatitis
-
Burt AD, Mutton A, Day CP. Diagnosis and interpretation of steatosis and steatohepatitis. Sem Diag Pathol 1998;15:246-58.
-
(1998)
Sem Diag Pathol
, vol.15
, pp. 246-258
-
-
Burt, A.D.1
Mutton, A.2
Day, C.P.3
-
16
-
-
0036829092
-
AGA technical review on nonalcoholic fatty liver disease
-
Sanyal AJ. AGA technical review on nonalcoholic fatty liver disease. Gastroenterology 2002;123:1705-25.
-
(2002)
Gastroenterology
, vol.123
, pp. 1705-1725
-
-
Sanyal, A.J.1
-
17
-
-
0027534980
-
Choline deficiency, lipotrope deficiency and the development of liver disease including liver cancer: A new perspective
-
Ghoshal AK, Farber E. Choline deficiency, lipotrope deficiency and the development of liver disease including liver cancer: a new perspective. Lab Invest 1993;68:255-60.
-
(1993)
Lab Invest
, vol.68
, pp. 255-260
-
-
Ghoshal, A.K.1
Farber, E.2
-
18
-
-
0035984958
-
Prevention/reversal of choline deficiency-induced steatohepatitis by a peroxisome proliferator activated receptor α ligand in rats
-
Rao MS, Kashireddy P, Musunuri S, Okonkwo A. Prevention/reversal of choline deficiency-induced steatohepatitis by a peroxisome proliferator activated receptor α ligand in rats. In Vivo 2002;16:145-52.
-
(2002)
In Vivo
, vol.16
, pp. 145-152
-
-
Rao, M.S.1
Kashireddy, P.2
Musunuri, S.3
Okonkwo, A.4
-
19
-
-
0034092716
-
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
-
Leclercq IA, Farrell GC, Field J, Bell DR, Gonzalez FJ, Robertson GR. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. J Clin Invest 2000;105:1067-75.
-
(2000)
J Clin Invest
, vol.105
, pp. 1067-1075
-
-
Leclercq, I.A.1
Farrell, G.C.2
Field, J.3
Bell, D.R.4
Gonzalez, F.J.5
Robertson, G.R.6
-
20
-
-
0742305244
-
Sex differences in choline deficient diet-induced steatohepatitis in mice
-
Kashireddy PV, Rao MS. Sex differences in choline deficient diet-induced steatohepatitis in mice. Exp Biol Med 2004;229:158-62.
-
(2004)
Exp Biol Med
, vol.229
, pp. 158-162
-
-
Kashireddy, P.V.1
Rao, M.S.2
-
21
-
-
0034102291
-
Alcoholic liver disease: New insights in pathogenesis lead to new treatments
-
Leiber C. Alcoholic liver disease: new insights in pathogenesis lead to new treatments. J Hepatol 2000;32(Suppl 1):113-28.
-
(2000)
J Hepatol
, vol.32
, Issue.SUPPL. 1
, pp. 113-128
-
-
Leiber, C.1
-
22
-
-
0035078484
-
Etiopathogenesis of nonalcoholic steatohepatitis
-
Chitturi S, Farrell GC. Etiopathogenesis of nonalcoholic steatohepatitis. Sem Liver Dis 2001;21:27-41.
-
(2001)
Sem Liver Dis
, vol.21
, pp. 27-41
-
-
Chitturi, S.1
Farrell, G.C.2
-
23
-
-
0036652185
-
Oxidative stress in the pathogenesis of nonalcoholic fatty liver disease, in rats fed a choline deficient diet
-
Olivera CP, da costa Gayotto LC, Tatai C, et al. Oxidative stress in the pathogenesis of nonalcoholic fatty liver disease, in rats fed a choline deficient diet. J Cell Mol Med 2002;6:399-406.
-
(2002)
J Cell Mol Med
, vol.6
, pp. 399-406
-
-
Olivera, C.P.1
Da Costa Gayotto, L.C.2
Tatai, C.3
-
24
-
-
0020035184
-
Stimulation of DNA synthesis and cell proliferation in the liver of rats fed a choline-devoid diet and their suppression by Phenobarbital
-
Abanobi SE, Lombardi B, Shinozuka H. Stimulation of DNA synthesis and cell proliferation in the liver of rats fed a choline-devoid diet and their suppression by Phenobarbital. Cancer Res 1982;42:412-5.
-
(1982)
Cancer Res
, vol.42
, pp. 412-415
-
-
Abanobi, S.E.1
Lombardi, B.2
Shinozuka, H.3
-
26
-
-
0033200054
-
Nonalcoholic steatohepatitis: A proposal for grading and staging the histological lesions
-
Brunt EM, Janney CG, Di Bisceglie AM, et al. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol 1999;94:2467-74.
-
(1999)
Am J Gastroenterol
, vol.94
, pp. 2467-2474
-
-
Brunt, E.M.1
Janney, C.G.2
Di Bisceglie, A.M.3
-
27
-
-
0344862102
-
Evaluation of cell proliferation in rat tissues with BrdU, PCNA Ki-67 (MIB-5) immunohistochemistry and in situ hybridization for histone mRNA
-
Muskhelishvili L, Latendresse JR, Kodell RL, Henderson EB. Evaluation of cell proliferation in rat tissues with BrdU, PCNA Ki-67 (MIB-5) immunohistochemistry and in situ hybridization for histone mRNA. J Histochem Cytochem 2003;51: 1681-8.
-
(2003)
J Histochem Cytochem
, vol.51
, pp. 1681-1688
-
-
Muskhelishvili, L.1
Latendresse, J.R.2
Kodell, R.L.3
Henderson, E.B.4
-
28
-
-
0034928367
-
Peroxisome proliferator-activated receptor-α-/- Mice show enhanced hepatocyte proliferation in response to the hepatomitogen 1,4-bis[2-(3,5- dichloropyridoxy)] benzene, a ligand of constitutive androstane receptor
-
Columbano A, Ledda-Columbano GM, Pibiri M, et al. Peroxisome proliferator-activated receptor-α-/- mice show enhanced hepatocyte proliferation in response to the hepatomitogen 1,4-bis[2-(3,5-dichloropyridoxy)] benzene, a ligand of constitutive androstane receptor. Hepatology 2001;34:262-6.
-
(2001)
Hepatology
, vol.34
, pp. 262-266
-
-
Columbano, A.1
Ledda-Columbano, G.M.2
Pibiri, M.3
-
29
-
-
0038643427
-
Central role of PPARα-dependent hepatic lipid turnover in dietary steatohepatitis in mice
-
Ip E, Farrell GC, Robertson G, Hall P, Kirsch R, Leclercq I. Central role of PPARα-dependent hepatic lipid turnover in dietary steatohepatitis in mice. Hepatology 2003;38:123-32.
-
(2003)
Hepatology
, vol.38
, pp. 123-132
-
-
Ip, E.1
Farrell, G.C.2
Robertson, G.3
Hall, P.4
Kirsch, R.5
Leclercq, I.6
-
30
-
-
0033976960
-
Estrogen is involved in early alcohol-induced liver injury in a rat enteral feeding model
-
Yin M, Ikejima K, Wheeler MD, et al. Estrogen is involved in early alcohol-induced liver injury in a rat enteral feeding model. Hepatology 2000;31:117-23.
-
(2000)
Hepatology
, vol.31
, pp. 117-123
-
-
Yin, M.1
Ikejima, K.2
Wheeler, M.D.3
-
31
-
-
0034235208
-
Metabolic and nutritional considerations in nonalcoholic fatty liver
-
Fong DG, Nehra V, Lindor KD, Buchman AL. Metabolic and nutritional considerations in nonalcoholic fatty liver. Hepatology 2000;32:3-10.
-
(2000)
Hepatology
, vol.32
, pp. 3-10
-
-
Fong, D.G.1
Nehra, V.2
Lindor, K.D.3
Buchman, A.L.4
-
32
-
-
0033516569
-
Peroxisomal and mitochondrial fatty acid β-oxidation in mice nullizygous for both peroxisome proliferator-activated receptor α and peroxisomal fatty acyl-CoA oxidase
-
Hashimoto T, Fujita T, Usuda N, et al. Peroxisomal and mitochondrial fatty acid β-oxidation in mice nullizygous for both peroxisome proliferator-activated receptor α and peroxisomal fatty acyl-CoA oxidase. J Biol Chem 1999;274:19228-36.
-
(1999)
J Biol Chem
, vol.274
, pp. 19228-19236
-
-
Hashimoto, T.1
Fujita, T.2
Usuda, N.3
-
33
-
-
0035078599
-
Animal models of steatosis
-
Koteish A, Diehl AM. Animal models of steatosis. Sem Liver Dis 2001;21:89-104.
-
(2001)
Sem Liver Dis
, vol.21
, pp. 89-104
-
-
Koteish, A.1
Diehl, A.M.2
-
34
-
-
0033562693
-
Non-alcoholic steatohepatitis: Another disease of affluence
-
James O, Day C. Non-alcoholic steatohepatitis: another disease of affluence. Lancet 1999:1634-6.
-
(1999)
Lancet
, pp. 1634-1636
-
-
James, O.1
Day, C.2
-
35
-
-
1042277044
-
Nonalcoholic fatty liver disease: An emerging pathophysiological spectrum
-
Zafrani ES. Nonalcoholic fatty liver disease: an emerging pathophysiological spectrum. Virch Arch 2004;444:3-12.
-
(2004)
Virch Arch
, vol.444
, pp. 3-12
-
-
Zafrani, E.S.1
-
36
-
-
0034676629
-
Cytokines in alcoholic and nonalcoholic steatohepatitis
-
Tilg H, Diehl AM. Cytokines in alcoholic and nonalcoholic steatohepatitis. N Engl J Med 2000;343:1467-76.
-
(2000)
N Engl J Med
, vol.343
, pp. 1467-1476
-
-
Tilg, H.1
Diehl, A.M.2
-
37
-
-
0029845271
-
Liver regeneration versus direct hyperplasia
-
Columbano A, Shinozuka H. Liver regeneration versus direct hyperplasia. FASEB J 1996;10:1118-28.
-
(1996)
FASEB J
, vol.10
, pp. 1118-1128
-
-
Columbano, A.1
Shinozuka, H.2
-
38
-
-
0036120125
-
Hepatic regeneration in peroxisome proliferator-activated receptor α-null mice after partial hepatectomy
-
Rao MS, Peters JM, Gonzalez FK, Reddy JK. Hepatic regeneration in peroxisome proliferator-activated receptor α-null mice after partial hepatectomy. Hep Res 2002;22:52-7.
-
(2002)
Hep Res
, vol.22
, pp. 52-57
-
-
Rao, M.S.1
Peters, J.M.2
Gonzalez, F.K.3
Reddy, J.K.4
-
39
-
-
0021025039
-
The rapid induction of liver cell death in rats fed a choline-deficient methionine-low diet
-
Goshal AK, Ahluwalia M, Farber E. The rapid induction of liver cell death in rats fed a choline-deficient methionine-low diet. Am J Pathol 1983;113:309-14.
-
(1983)
Am J Pathol
, vol.113
, pp. 309-314
-
-
Goshal, A.K.1
Ahluwalia, M.2
Farber, E.3
-
40
-
-
0027818830
-
Proliferating cell nuclear antigen: A marker for hepatocellular proliferation in rodents
-
Eldridge SR, Butterworth BE, Goldsworthy TL. Proliferating cell nuclear antigen: a marker for hepatocellular proliferation in rodents. Environ Health Perspect 1993;101(sup.5):211-8.
-
(1993)
Environ Health Perspect
, vol.101
, Issue.SUPPL. 5
, pp. 211-218
-
-
Eldridge, S.R.1
Butterworth, B.E.2
Goldsworthy, T.L.3
|