Dysregulation of hypoxia-inducible factor by presenilin/γ-secretase loss-of-function mutations

Journal of Neuroscience

Volumn 33, Issue 5, 2013, Pages 1915-1926

  Kaufmann, Muriel R ^a   Barth, Sandra ^a,d   Konietzko, Uwe ^a   Wu, Bei ^b   Egger, Sascha ^a   Kunze, Reiner ^c   Marti, Hugo H ^c   Hick, Meike ^c   Müller, Ulrike ^c   Camenisch, Gieri ^a   Wenger, Roland H ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d YES Pharmaceutical Development Services GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; CARBONATE DEHYDRATASE; FK 506 BINDING PROTEIN; GAMMA SECRETASE; HYPOXIA INDUCIBLE FACTOR; MESSENGER RNA; MYC PROTEIN; PRESENILIN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEIN BNIP3; TEBUFENOZIDE; VASCULOTROPIN A;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; FIBROBLAST; GENE INACTIVATION; GENETIC TRANSFECTION; HYPOXIA; IMMUNOBLOTTING; LOSS OF FUNCTION MUTATION; MALE; MOUSE; NONHUMAN; OXYGEN SENSING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANOXIA; CEREBRAL CORTEX; FIBROBLASTS; HYPOXIA-INDUCIBLE FACTOR 1; MICE; MUTATION; NEURONS; PRESENILIN-1; TRANSCRIPTIONAL ACTIVATION;

EID: 84873044282     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3402-12.2013     Document Type: Article

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