메뉴 건너뛰기




Volumn 7, Issue 10, 2009, Pages 1663-1671

Notch signal activates hypoxia pathway through HES1-dependent SRC/signal transducers and activators of transcription 3 pathway

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; NOTCH RECEPTOR; PROTEIN TYROSINE KINASE; STAT3 PROTEIN; TRANSCRIPTION FACTOR HES 1; TRICHOSTATIN A;

EID: 72449173021     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-09-0191     Document Type: Article
Times cited : (39)

References (48)
  • 1
    • 0033920919 scopus 로고    scopus 로고
    • Notch signal transduction: A real Rip and more
    • DOI 10.1016/S0959-437X(00)00097-6
    • Weinmaster G. Notch signal transduction: a real rip and more. Curr Opin Genet Dev 2000;10:363-369 (Pubitemid 30450038)
    • (2000) Current Opinion in Genetics and Development , vol.10 , Issue.4 , pp. 363-369
    • Weinmaster, G.1
  • 2
    • 0037363922 scopus 로고    scopus 로고
    • HES and HERP families: Multiple effectors of the Notch signaling pathway
    • DOI 10.1002/jcp.10208
    • Iso T, Kedes L, Hamamori Y. HES and HERP families: multiple effectors of the Notch signaling pathway. J Cell Physiol 2003;194:237-255 (Pubitemid 36176887)
    • (2003) Journal of Cellular Physiology , vol.194 , Issue.3 , pp. 237-255
    • Iso, T.1    Kedes, L.2    Hamamori, Y.3
  • 5
    • 0033233243 scopus 로고    scopus 로고
    • Regulation of mammalian O2 homeostasis by hypoxiainducible factor 1
    • Semenza GL. Regulation of mammalian O2 homeostasis by hypoxiainducible factor 1. Annu Rev Cell Dev Biol 1999;15:551-578
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 8
    • 0037033095 scopus 로고    scopus 로고
    • Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes
    • DOI 10.1074/jbc.M204938200
    • Miyazaki K, Kawamoto T, Tanimoto K, Nishiyama M, Honda H, Kato Y Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes. J Biol Chem 2002;277:47014-47021 (Pubitemid 36159208)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.49 , pp. 47014-47021
    • Miyazaki, K.1    Kawamoto, T.2    Tanimoto, K.3    Nishiyama, M.4    Honda, H.5    Kato, Y.6
  • 9
    • 0242330181 scopus 로고    scopus 로고
    • Oxygen sensing in the hypoxic response pathway: Regulation of the hypoxia-inducible transcription factor
    • Bruick RK. Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor. Genes Dev 2003;17:2614-2623
    • (2003) Genes Dev , vol.17 , pp. 2614-2623
    • Bruick, R.K.1
  • 11
    • 0026075610 scopus 로고
    • Hypoxia-inducible nuclear factors bind to an enhancer element located 3́ to the human erythropoietin gene
    • Semenza GL, Nejfelt MK, Chi SM, Antonarakis SE. Hypoxia-inducible nuclear factors bind to an enhancer element located 3́ to the human erythropoietin gene. Proc Natl Acad Sci U S A 1991;88:5680-5684
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 5680-5684
    • Semenza, G.L.1    Nejfelt, M.K.2    Chi, S.M.3    Antonarakis, S.E.4
  • 12
    • 25444506836 scopus 로고    scopus 로고
    • Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function
    • DOI 10.1158/0008-5472.CAN-05-1208
    • Patel NS, Li JL, Generali D, Poulsom R, Cranston DW, Harris AL. Upregulation of δ-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function. Cancer Res 2005;65:8690-8697 (Pubitemid 41377356)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8690-8697
    • Patel, N.S.1    Li, J.-L.2    Generali, D.3    Poulsom, R.4    Cranston, D.W.5    Harris, A.L.6
  • 13
    • 0035753241 scopus 로고    scopus 로고
    • Delta4, an endothelial specific Notch ligand expressed at sites of physiological and tumor angiogenesis
    • Mailhos C, Modlich U, Lewis J, Harris A, Bicknell R, Ish-Horowicz D. Δ4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis. Differentiation 2001;69:135-144 (Pubitemid 33755062)
    • (2001) Differentiation , vol.69 , Issue.2-3 , pp. 135-144
    • Mailhos, C.1    Modlich, U.2    Lewis, J.3    Harris, A.4    Bicknell, R.5    Ish-Horowicz, D.6
  • 15
    • 33745092023 scopus 로고    scopus 로고
    • Notch signaling in the regulation of tumor angiogenesis
    • DOI 10.1016/j.tcb.2006.04.003, PII S0962892406001164
    • Rehman AO, Wang CY. Notch signaling in the regulation of tumor angiogenesis. Trends Cell Biol 2006;16:293-300. (Pubitemid 43884979)
    • (2006) Trends in Cell Biology , vol.16 , Issue.6 , pp. 293-300
    • Rehman, A.O.1    Wang, C.-Y.2
  • 17
    • 23444449093 scopus 로고    scopus 로고
    • STAT3 is a potential modulator of HIF-1- Mediated VEGF expression in human renal carcinoma cells
    • Jung JE, Lee HG, Cho IH, et al. STAT3 is a potential modulator of HIF-1- mediated VEGF expression in human renal carcinoma cells. FASEB J 2005;19: 1296-1298
    • (2005) FASEB J , vol.19 , pp. 1296-1298
    • Jung, J.E.1    Lee, H.G.2    Cho, I.H.3
  • 18
    • 18844444774 scopus 로고    scopus 로고
    • HIF-1α, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
    • DOI 10.1038/sj.onc.1208513
    • Gray MJ, Zhang J, Ellis LM, et al. HIF-1α, STAT3, CBP/p300 and Ref-1/ APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas. Oncogene 2005;24:3110-3120 (Pubitemid 40695080)
    • (2005) Oncogene , vol.24 , Issue.19 , pp. 3110-3120
    • Gray, M.J.1    Zhang, J.2    Ellis, L.M.3    Semenza, G.L.4    Evans, D.B.5    Watowich, S.S.6    Gallick, G.E.7
  • 19
    • 2942709503 scopus 로고    scopus 로고
    • Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling
    • DOI 10.1038/ncb1138
    • Kamakura S, Oishi K, Yoshimatsu T, Nakafuku M, Masuyama N, Gotoh Y. Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling. Nat Cell Biol 2004;6:547-554 (Pubitemid 38786598)
    • (2004) Nature Cell Biology , vol.6 , Issue.6 , pp. 547-554
    • Kamakura, S.1    Oishi, K.2    Yoshimatsu, T.3    Nakafuku, M.4    Masuyama, N.5    Gotoh, Y.6
  • 20
    • 34347335705 scopus 로고    scopus 로고
    • Cross talk between Notch and growth factor/cytokine signaling pathways in neural stem cells
    • DOI 10.1128/MCB.00170-07
    • Nagao M, Sugimori M, Nakafuku M. Cross talk between notch and growth factor/cytokine signaling pathways in neural stem cells. Mol Cell Biol 2007;27: 3982-3994 (Pubitemid 47010996)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.11 , pp. 3982-3994
    • Nagao, M.1    Sugimori, M.2    Nakafuku, M.3
  • 21
    • 0028349735 scopus 로고
    • Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
    • Zhong Z, Wen Z, Darnell JE, Jr. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin- 6. Science 1994;264:95-98 (Pubitemid 24144493)
    • (1994) Science , vol.264 , Issue.5155 , pp. 95-98
    • Zhong, Z.1    Wen, Z.2    Darnell Jr., J.E.3
  • 22
    • 0028117163 scopus 로고
    • Cytokine signal transduction
    • Kishimoto T, Taga T, Akira S. Cytokine signal transduction. Cell 1994;76: 253-262
    • (1994) Cell , vol.76 , pp. 253-262
    • Kishimoto, T.1    Taga, T.2    Akira, S.3
  • 23
    • 0029069145 scopus 로고
    • Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
    • Schindler C, Darnell JE, Jr. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu Rev Biochem 1995;64:621-651
    • (1995) Annu Rev Biochem , vol.64 , pp. 621-651
    • Schindler, C.1    Darnell Jr., J.E.2
  • 24
    • 33845865825 scopus 로고    scopus 로고
    • Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment
    • Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol 2007; 7:41-51.
    • (2007) Nat Rev Immunol , vol.7 , pp. 41-51
    • Yu, H.1    Kortylewski, M.2    Pardoll, D.3
  • 25
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell JE, Jr. STATs and gene regulation. Science 1997;277:1630-1635
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell Jr., J.E.1
  • 26
    • 0029960028 scopus 로고    scopus 로고
    • Dominant negative Stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction
    • DOI 10.1074/jbc.271.11.5961
    • Kaptein A, Paillard V, Saunders M. Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction. J Biol Chem 1996;271: 5961-5964 (Pubitemid 26095392)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.11 , pp. 5961-5964
    • Kaptein, A.1    Paillard, V.2    Saunders, M.3
  • 27
    • 0028786276 scopus 로고
    • The Janus protein tyrosine kinase family and its role in cytokine signaling
    • Ihle JN. The Janus protein tyrosine kinase family and its role in cytokine signaling. Adv Immunol 1995;60:1-35.
    • (1995) Adv Immunol , vol.60 , pp. 1-35
    • Ihle, J.N.1
  • 30
    • 33746897689 scopus 로고    scopus 로고
    • Identification of STAT3 as a specific substrate of breast tumor kinase
    • DOI 10.1038/sj.onc.1209501, PII 1209501
    • Liu L, Gao Y, Qiu H, Miller WT, Poli V, Reich NC. Identification of STAT3 as a specific substrate of breast tumor kinase. Oncogene 2006;25:4904-4912 (Pubitemid 44201181)
    • (2006) Oncogene , vol.25 , Issue.35 , pp. 4904-4912
    • Liu, L.1    Gao, Y.2    Qiu, H.3    Miller, W.T.4    Poli, V.5    Reich, N.C.6
  • 31
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxiainducible factor 1
    • Wang GL, Semenza GL. Purification and characterization of hypoxiainducible factor 1. J Biol Chem 1995;270:1230-1237
    • (1995) J Biol Chem , vol.270 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 32
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell PH, Wiesener MS, Chang GW, et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 1999;399:271-275
    • (1999) Nature , vol.399 , pp. 271-275
    • Maxwell, P.H.1    Wiesener, M.S.2    Chang, G.W.3
  • 36
    • 27544504795 scopus 로고    scopus 로고
    • The hairy and enhancer of split 1 is a negative regulator of the repressor element silencer transcription factor
    • DOI 10.1016/j.febslet.2005.09.093, PII S001457930501238X
    • Abderrahmani A, Niederhauser G, Lenain V, Regazzi R, Waeber G. The hairy and enhancer of split 1 is a negative regulator of the repressor element silencer transcription factor. FEBS Lett 2005;579:6199-6204 (Pubitemid 41546268)
    • (2005) FEBS Letters , vol.579 , Issue.27 , pp. 6199-6204
    • Abderrahmani, A.1    Niederhauser, G.2    Lenain, V.3    Regazzi, R.4    Waeber, G.5
  • 38
    • 20444399897 scopus 로고    scopus 로고
    • The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation
    • DOI 10.1016/j.str.2005.03.012, PII S096921260500136X
    • Cowan-Jacob SW, Fendrich G, Manley PW, et al. The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation. Structure 2005;13:861-871 (Pubitemid 40804389)
    • (2005) Structure , vol.13 , Issue.6 , pp. 861-871
    • Cowan-Jacob, S.W.1    Fendrich, G.2    Manley, P.W.3    Jahnke, W.4    Fabbro, D.5    Liebetanz, J.6    Meyer, T.7
  • 39
    • 21244439543 scopus 로고    scopus 로고
    • Down-regulation of the tumor suppressor gene COOH-terminal Src kinase: An early event during premalignant colonic epithelial hyperproliferation
    • Kunte DP, Wali RK, Koetsier JL, et al. Down-regulation of the tumor suppressor gene COOH-terminal Src kinase: an early event during premalignant colonic epithelial hyperproliferation. FEBS Lett 2005;579:3497-3502
    • (2005) FEBS Lett , vol.579 , pp. 3497-3502
    • Kunte, D.P.1    Wali, R.K.2    Koetsier, J.L.3
  • 40
    • 45549107045 scopus 로고    scopus 로고
    • Lack of nuclear expression of hairy and enhancer of split-1 (HES1) in pancreatic endocrine tumors
    • DOI 10.1055/s-2008-1076695, Endocrine-related Tumors
    • Johansson T, Lejonklou MH, Ekeblad S, Stalberg P, Skogseid B. Lack of nuclear expression of hairy and enhancer of split-1 (HES1) in pancreatic endocrine tumors. Horm Metab Res 2008;40:354-359 (Pubitemid 351859448)
    • (2008) Hormone and Metabolic Research , vol.40 , Issue.5 , pp. 354-359
    • Johansson, T.1    Lejonklou, M.H.2    Ekeblad, S.3    Stalberg, P.4    Skogseid, B.5
  • 41
    • 66349100751 scopus 로고    scopus 로고
    • Combined in silico and in vivo analyses reveal role of Hes1 in taste cell differentiation
    • Ota MS, Kaneko Y, Kondo K, et al. Combined in silico and in vivo analyses reveal role of Hes1 in taste cell differentiation. PLoS Genet 2009;5: e1000443.
    • (2009) PLoS Genet , vol.5
    • Ota, M.S.1    Kaneko, Y.2    Kondo, K.3
  • 42
    • 34547922380 scopus 로고    scopus 로고
    • Delta-Notch-and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors
    • DOI 10.1093/nar/gkm477
    • Fischer A, Gessler M. Δ3B-Notch-and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors. Nucleic Acids Res 2007;35: 4583-4596 (Pubitemid 47250333)
    • (2007) Nucleic Acids Research , vol.35 , Issue.14 , pp. 4583-4596
    • Fischer, A.1    Gessler, M.2
  • 45
    • 10044271901 scopus 로고    scopus 로고
    • HES-1 inhibits 17β-estradiol and heregulin-β1-mediated upregulation of E2F-1
    • DOI 10.1038/sj.onc.1208139
    • Hartman J, Muller P, Foster JS, Wimalasena J, Gustafsson JA, Strom A. HES-1 inhibits 17β-estradiol and heregulin-β1-mediated upregulation of E2F-1. Oncogene 2004;23:8826-8833 (Pubitemid 39610444)
    • (2004) Oncogene , vol.23 , Issue.54 , pp. 8826-8833
    • Hartman, J.1    Muller, P.2    Foster, J.S.3    Wimalasena, J.4    Gustafsson, J.-A.5    Strom, A.6
  • 46
    • 0035958877 scopus 로고    scopus 로고
    • Activation of NF-κB via the IκB Kinase Complex is Both Essential and Sufficient for Proinflammatory Gene Expression in Primary Endothelial Cells
    • DOI 10.1074/jbc.M102698200
    • Denk A, Goebeler M, Schmid S, et al. Activation of NF-κ B via the Iκ B kinase complex is both essential and sufficient for proinflammatory gene expression in primary endothelial cells. J Biol Chem 2001;276:28451-28458 (Pubitemid 37391556)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.30 , pp. 28451-28458
    • Denk, A.1    Goebeler, M.2    Schmid, S.3    Berberich, I.4    Ritz, O.5    Lindemann, D.6    Ludwig, S.7    Wirth, T.8
  • 48
    • 12244251445 scopus 로고    scopus 로고
    • Stat3 dimerization regulated by reversible acetylation of a single lysine residue
    • DOI 10.1126/science.1105166
    • Yuan ZL, Guan YJ, Chatterjee D, Chin YE. Stat3 dimerization regulated by reversible acetylation of a single lysine residue. Science 2005;307:269-273 (Pubitemid 40116244)
    • (2005) Science , vol.307 , Issue.5707 , pp. 269-273
    • Yuan, Z.-L.1    Guan, Y.-J.2    Chatterjee, D.3    Chin, Y.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.