Alleles at the Nicastrin locus modify presenilin 1-deficiency phenotype

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 22, 2002, Pages 14452-14457

  Rozmahel, Richard ^a,b,e   Mount, Howard T J ^a,c   Chen, Fusheng ^a   Nguyen, Van ^a,b   Huang, Jean ^a,b   Erdebil, Serap ^a   Liauw, Jennifer ^a   Yu, Gang ^a   Hasegawa, Hiroshe ^a   Gu, Yongjun ^a   Song, You Qiang ^a   Schmidt, Stephen D ^d   Nixon, Ralph A ^a,c   Mathews, Paul M ^d   Bergeron, Catherine ^a,c   Fraser, Paul ^a   Westaway, David ^a   St George Hyslop, Peter ^a,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c University Health Network   (United States)

^d NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NICASTRIN; NOTCH RECEPTOR; PRESENILIN 1;

ALLELISM; ALZHEIMER DISEASE; ANIMAL MODEL; ARTICLE; CHROMOSOME 1; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION; GENE LOCUS; GENETIC ANALYSIS; GENOTYPE; MISSENSE MUTATION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ALLELES; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BINDING SITES; BREEDING; CHROMOSOME MAPPING; ENDOPEPTIDASES; FEMALE; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PEPTIDE FRAGMENTS; PHENOTYPE; PRESENILIN-1; RECEPTORS, NOTCH; SPINE;

ANIMALIA; VERTEBRATA;

EID: 0037195102     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.222413999     Document Type: Article

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