Interaction of presenilins with FKBP38 promotes apoptosis by reducing mitochondrial Bcl-2

Human Molecular Genetics

Volumn 14, Issue 13, 2005, Pages 1889-1902

  Wang, Hua Qin ^a,d   Nakaya, Yoshifumi ^a,d   Du, Zhenyu ^a   Yamane, Takuya ^a   Shirane, Michiko ^b   Kudo, Takashi ^c   Takeda, Masatoshi ^c   Takebayashi, Koichi ^a   Noda, Yoichi ^a   Nakayama, Keiichi I ^b   Nishimura, Masaki ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 38; GAMMA SECRETASE; IMMUNOPHILIN; MEMBRANE PROTEIN; MITOCHONDRIAL PROTEIN; PRESENILIN 1; PRESENILIN 2; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPETITION; COMPLEX FORMATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; FAMILIAL DISEASE; GENE DELETION; GOLGI COMPLEX; MACROMOLECULE; MITOCHONDRIAL MEMBRANE; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY MECHANISM;

ALZHEIMER DISEASE; ANIMALS; APOPTOSIS; HUMANS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; PRESENILIN-1; PRESENILIN-2; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-BCL-2; TACROLIMUS BINDING PROTEINS;

EID: 25844499702     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddi195     Document Type: Article

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