Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels: Evidence for an autoregulatory oxygen-sensing system

Journal of Biological Chemistry

Volumn 281, Issue 33, 2006, Pages 23482-23491

  Stiehl, Daniel P ^a   Wirthner, Renato ^a   Köditz, Jens ^a   Spielmann, Patrick ^b   Camenisch, Gieri ^a   Wenger, Roland H ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; HYDROXYLATION; OXYGEN; OXYGEN SENSORS; TISSUE;

DOWN-REGULATION; OXYGEN CO-SUBSTRATES; OXYGEN-SENSING SYSTEMS; RE-OXYGENATION;

PROTEINS;

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; OXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLYL 4 HYDROXYLASE 2; PROLYL 4 HYDROXYLASE 3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOREGULATION; CONTROLLED STUDY; ENZYME INDUCTION; GENE EXPRESSION; HYDROXYLATION; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OXYGEN SENSING; OXYGEN TISSUE LEVEL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; REPORTER GENE; TISSUE OXYGENATION; TISSUE SPECIFICITY; UPREGULATION;

ANIMALS; CELL HYPOXIA; CELL LINE, TUMOR; CELLS, CULTURED; ENZYME INDUCTION; HOMEOSTASIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISOENZYMES; MICE; OXYGEN; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEIN STRUCTURE, TERTIARY; RNA, MESSENGER; UP-REGULATION;

EID: 33747660292     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M601719200     Document Type: Article

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