-
1
-
-
33646190173
-
Gene silencing through RNA interference (RNAi) in vivo: Strategies based on the direct application of siRNAs
-
16413079 1:CAS:528:DC%2BD28Xltl2isL8%3D
-
Aigner A. Gene silencing through RNA interference (RNAi) in vivo: strategies based on the direct application of siRNAs. J Biotechnol. 2006;124:12-25.
-
(2006)
J Biotechnol
, vol.124
, pp. 12-25
-
-
Aigner, A.1
-
2
-
-
0036892681
-
RNA silencing of dengue virus type 2 replication in transformed C6/36 mosquito cells transcribing an inverted-repeat RNA derived from the virus genome
-
Aldeman ZN, Sanchez-Vargas I, Travanty EA, Carlson JO, Beaty BJ, Blair CD, Olsen KE. RNA silencing of dengue virus type 2 replication in transformed C6/36 mosquito cells transcribing an inverted-repeat RNA derived from the virus genome. J Virol. 2002;76:12925-33.
-
(2002)
J Virol
, vol.76
, pp. 12925-12933
-
-
Aldeman, Z.N.1
Sanchez-Vargas, I.2
Travanty, E.A.3
Carlson, J.O.4
Beaty, B.J.5
Blair, C.D.6
Olsen, K.E.7
-
3
-
-
0037273564
-
Gene silencing in Caenorhabditis elegans by transitive RNA interference
-
12554873 1:CAS:528:DC%2BD3sXhtFahs74%3D
-
Alder MN, Dames S, Gaudet J, Mango SE. Gene silencing in Caenorhabditis elegans by transitive RNA interference. RNA. 2003;9:25-32.
-
(2003)
RNA
, vol.9
, pp. 25-32
-
-
Alder, M.N.1
Dames, S.2
Gaudet, J.3
Mango, S.E.4
-
4
-
-
58049196894
-
RNA-based viral immunity initiated by the Dicer family of host immune receptors
-
Aliyari R, Ding SW. RNA-based viral immunity initiated by the Dicer family of host immune receptors. Immunol Rev. 2009;176-188.
-
(2009)
Immunol Rev.
, pp. 176-188
-
-
Aliyari, R.1
Ding, S.W.2
-
5
-
-
44349138378
-
Identification of innate immunity genes and pathways using a comparative genomics approach
-
18463287 1:CAS:528:DC%2BD1cXmt1Ghsbw%3D
-
Alper S, Laws R, Lackford B, Boyd WA, Dunlap P, Freedman JH, Schwartz DA. Identification of innate immunity genes and pathways using a comparative genomics approach. Proc Natl Acad Sci USA. 2008;105:7016-21.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 7016-7021
-
-
Alper, S.1
Laws, R.2
Lackford, B.3
Boyd, W.A.4
Dunlap, P.5
Freedman, J.H.6
Schwartz, D.A.7
-
6
-
-
26944498261
-
Approaches for chemically synthesized siRNA and vector-mediated RNAi
-
16199038 1:CAS:528:DC%2BD2MXhtFKmtbnK
-
Amarzguioui M, Rossi JJ, Kim D. Approaches for chemically synthesized siRNA and vector-mediated RNAi. FEBS Lett. 2005;579:5974-81.
-
(2005)
FEBS Lett
, vol.579
, pp. 5974-5981
-
-
Amarzguioui, M.1
Rossi, J.J.2
Kim, D.3
-
7
-
-
0037737975
-
MicroRNAs and other tiny endogenous RNAs in C. elegans
-
Ambrose V, Lee RC, Lavanway A, Williams PT, Jewell D. MicroRNAs and other tiny endogenous RNAs in C. elegans. Curr Biol. 2003;13:807-18.
-
(2003)
Curr Biol
, vol.13
, pp. 807-818
-
-
Ambrose, V.1
Lee, R.C.2
Lavanway, A.3
Williams, P.T.4
Jewell, D.5
-
8
-
-
0032573210
-
A viral suppressor of gene silencing in plants
-
9789044 1:CAS:528:DyaK1cXntFWkurk%3D
-
Anandalakshmi R, Pruss GJ, Ge X, Marathe R, Mallory AC, Smith TH, Vance VB. A viral suppressor of gene silencing in plants. Proc Natl Acad Sci USA. 1998;95:13079-84.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13079-13084
-
-
Anandalakshmi, R.1
Pruss, G.J.2
Ge, X.3
Marathe, R.4
Mallory, A.C.5
Smith, T.H.6
Vance, V.B.7
-
9
-
-
0035838369
-
Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germ line
-
11470406 1:CAS:528:DC%2BD3MXltlOgs7s%3D
-
Aravin AA, Naumova NM, Tulin AT, Vagin VV, Rozovsky YM, Gvozdev VA. Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germ line. Curr Biol. 2001;11:1017-27.
-
(2001)
Curr Biol
, vol.11
, pp. 1017-1027
-
-
Aravin, A.A.1
Naumova, N.M.2
Tulin, A.T.3
Vagin, V.V.4
Rozovsky, Y.M.5
Gvozdev, V.A.6
-
10
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartell DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116:281-97.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartell, D.P.1
-
12
-
-
4644242349
-
RNA silencing in plants
-
15372043 1:CAS:528:DC%2BD2cXnsFaiu7c%3D
-
Baulcombe D. RNA silencing in plants. Nature. 2004;431:356-63.
-
(2004)
Nature
, vol.431
, pp. 356-363
-
-
Baulcombe, D.1
-
13
-
-
20444379611
-
RNA silencing
-
15950871 1:CAS:528:DC%2BD2MXltFCks74%3D
-
Baulcombe D. RNA silencing. Trends Biochem Sci. 2005;30:290-3.
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 290-293
-
-
Baulcombe, D.1
-
14
-
-
0032567413
-
Infection of tobacco or Arabidopsis plants by CMV counteracts systemic post-transcriptional silencing of nonviral (trans) genes
-
9878609 1:CAS:528:DyaK1MXjtFequg%3D%3D
-
Beclin C, Berthome R, Palaqui JC, Tepfer M, Vaucheret H. Infection of tobacco or Arabidopsis plants by CMV counteracts systemic post-transcriptional silencing of nonviral (trans) genes. Virology. 1998;252:313-7.
-
(1998)
Virology
, vol.252
, pp. 313-317
-
-
Beclin, C.1
Berthome, R.2
Palaqui, J.C.3
Tepfer, M.4
Vaucheret, H.5
-
15
-
-
41949113026
-
Expression, function and regulation of Brachyenteron in the short germband insect Tribolium castaneum
-
18392878 1:CAS:528:DC%2BD1cXksVKlsbY%3D
-
Berns N, Kusch T, Schroder R, Reuter R. Expression, function and regulation of Brachyenteron in the short germband insect Tribolium castaneum. Dev Genes Evol. 2008;218:169-79.
-
(2008)
Dev Genes Evol
, vol.218
, pp. 169-179
-
-
Berns, N.1
Kusch, T.2
Schroder, R.3
Reuter, R.4
-
16
-
-
0242266620
-
Dicer is essential for mouse development
-
14528307 1:CAS:528:DC%2BD3sXosFWrtrs%3D
-
Bernstein E, Kim SY, Carmell MA, Murchinson EP, Alcorn H, Li MZ, Mills AA, Elledge SJ, Anderson KV, Hannon GJ. Dicer is essential for mouse development. Nature Genet. 2003;35:215-7.
-
(2003)
Nature Genet
, vol.35
, pp. 215-217
-
-
Bernstein, E.1
Kim, S.Y.2
Carmell, M.A.3
Murchinson, E.P.4
Alcorn, H.5
Li, M.Z.6
Mills, A.A.7
Elledge, S.J.8
Anderson, K.V.9
Hannon, G.J.10
-
17
-
-
0036898747
-
Specific developmental gene silencing in the honey bee using a homeobox motif
-
12421410 1:CAS:528:DC%2BD38XptlKisr8%3D
-
Beye M, Hartel S, Hagen A, Hasselmann M, Omholt SW. Specific developmental gene silencing in the honey bee using a homeobox motif. Insect Mol Biol. 2002;11:527-32.
-
(2002)
Insect Mol Biol
, vol.11
, pp. 527-532
-
-
Beye, M.1
Hartel, S.2
Hagen, A.3
Hasselmann, M.4
Omholt, S.W.5
-
18
-
-
0035813684
-
Chitosans for gene delivery
-
11718938 1:CAS:528:DC%2BD3MXosFKltbY%3D
-
Borchard G. Chitosans for gene delivery. Adv Drug Deliv Rev. 2001;52:145-50.
-
(2001)
Adv Drug Deliv Rev
, vol.52
, pp. 145-150
-
-
Borchard, G.1
-
19
-
-
0029160083
-
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
-
7638184 1:CAS:528:DyaK2MXntlKmt7s%3D
-
Boussif O, Lezoulach F, Zanta MA, Mergny MD, Scherman D, Demeneix B, Bher JP. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci USA. 1995;92:7297-301.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7297-7301
-
-
Boussif, O.1
Lezoulach, F.2
Zanta, M.A.3
Mergny, M.D.4
Scherman, D.5
Demeneix, B.6
Bher, J.P.7
-
20
-
-
0036675642
-
Specific degradation of 3′ regions of GUS mRNA in posttranscriptionally silenced tobacco lines may be related to 5′-3′ spreading of silencing
-
12212847 1:CAS:528:DC%2BD38XmsFamsbs%3D
-
Braunstein TH, Moury B, Johannessen M, Albreshtsen M. Specific degradation of 3′ regions of GUS mRNA in posttranscriptionally silenced tobacco lines may be related to 5′-3′ spreading of silencing. RNA. 2002;8:1034-44.
-
(2002)
RNA
, vol.8
, pp. 1034-1044
-
-
Braunstein, T.H.1
Moury, B.2
Johannessen, M.3
Albreshtsen, M.4
-
21
-
-
0032538794
-
Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana
-
9822616 1:CAS:528:DyaK1cXnvF2jtLw%3D
-
Brigneti G, Voinnet O, Li WX, Ji LH, Ding SW, Baulcombe DC. Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana. EMBO J. 1998;17:6739-46.
-
(1998)
EMBO J
, vol.17
, pp. 6739-6746
-
-
Brigneti, G.1
Voinnet, O.2
Li, W.X.3
Ji, L.H.4
Ding, S.W.5
Baulcombe, D.C.6
-
22
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
11910072 1:CAS:528:DC%2BD38XjtFCjtrk%3D
-
Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science. 2002;296:550-3.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
23
-
-
33751099034
-
RNAi therapeutics: A potential new class of pharmaceutical drugs
-
17108989 1:CAS:528:DC%2BD28Xht1SrtLfO
-
Bumcrot D, Manoharan M, Koteliansky V, Sah DW. RNAi therapeutics: a potential new class of pharmaceutical drugs. Nat Chem Biol. 2006;2:711-9.
-
(2006)
Nat Chem Biol
, vol.2
, pp. 711-719
-
-
Bumcrot, D.1
Manoharan, M.2
Koteliansky, V.3
Sah, D.W.4
-
24
-
-
33646188259
-
3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets
-
Burmingham A, Anderson EM, Reynolds A, Ilsley-Tyree D, Leake D, Fedorov Y, Baskerville S, Maksimova E, Robinson K, Karpilow J, Marshall WS, Khvorova A. 3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets. Nat Methods. 2006;3:199-204.
-
(2006)
Nat Methods
, vol.3
, pp. 199-204
-
-
Burmingham, A.1
Anderson, E.M.2
Reynolds, A.3
Ilsley-Tyree, D.4
Leake, D.5
Fedorov, Y.6
Baskerville, S.7
Maksimova, E.8
Robinson, K.9
Karpilow, J.10
Marshall, W.S.11
Khvorova, A.12
-
25
-
-
0035859929
-
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
-
11481446 1:CAS:528:DC%2BD3MXmtlCmsrY%3D
-
Caplen NJ, Parrish S, Imani F, Fire A, Morgan RA. Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc Natl Acad Sci USA. 2001;98:9742-7.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9742-9747
-
-
Caplen, N.J.1
Parrish, S.2
Imani, F.3
Fire, A.4
Morgan, R.A.5
-
26
-
-
0036664838
-
Inhibition of viral gene expression and replication in mosquito cells by dsRNA-triggered RNA interference
-
12161191 1:CAS:528:DC%2BD38XmtFaqs70%3D
-
Caplen NJ, Zheng Z, Falgout B, Morgan RA. Inhibition of viral gene expression and replication in mosquito cells by dsRNA-triggered RNA interference. Mol Ther. 2002;6:243-51.
-
(2002)
Mol Ther
, vol.6
, pp. 243-251
-
-
Caplen, N.J.1
Zheng, Z.2
Falgout, B.3
Morgan, R.A.4
-
27
-
-
0037232973
-
Silence of the strands: RNA interference in eukaryotic pathogens
-
12526853 1:CAS:528:DC%2BD3sXjtFygtw%3D%3D
-
Cottrell TR, Doering TL. Silence of the strands: RNA interference in eukaryotic pathogens. Trends Microbiol. 2003;11:37-43.
-
(2003)
Trends Microbiol
, vol.11
, pp. 37-43
-
-
Cottrell, T.R.1
Doering, T.L.2
-
28
-
-
0025949812
-
Adenovirus enhancement of transferrin-polysine-mediated gene delivery
-
1681545 1:CAS:528:DyaK38XhtlOn
-
Curiel DT, Agarwal S, Wagner E, Cotten M. Adenovirus enhancement of transferrin-polysine-mediated gene delivery. Proc Natl Acad Sci USA. 1991;88:8850-4.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 8850-8854
-
-
Curiel, D.T.1
Agarwal, S.2
Wagner, E.3
Cotten, M.4
-
29
-
-
38149045135
-
Inhibition of red seabream iridovirus (RSIV) replication by small interfering RNA (siRNA) in a cell culture system
-
18037509 1:CAS:528:DC%2BD1cXotlOltw%3D%3D
-
Dang LT, Kondo H, Hirono I, Aoki T. Inhibition of red seabream iridovirus (RSIV) replication by small interfering RNA (siRNA) in a cell culture system. Antiviral Res. 2008;77:142-9.
-
(2008)
Antiviral Res
, vol.77
, pp. 142-149
-
-
Dang, L.T.1
Kondo, H.2
Hirono, I.3
Aoki, T.4
-
30
-
-
39549117983
-
Delivery vehicles for small interfering RNA in vivo
-
18257677
-
de Fougerolles AR. Delivery vehicles for small interfering RNA in vivo. Hum Gene Ther. 2008;19:125-32.
-
(2008)
Hum Gene Ther
, vol.19
, pp. 125-132
-
-
De Fougerolles, A.R.1
-
31
-
-
11844251207
-
RNA interference in vivo: Toward synthetic small inhibitory RNA-based therapeutics
-
15644187
-
de Fougerolles AR, Manoharan M, Meyers R, Vornlocher HP. RNA interference in vivo: toward synthetic small inhibitory RNA-based therapeutics. Methods Enzymol. 2005;392:278-96.
-
(2005)
Methods Enzymol
, vol.392
, pp. 278-296
-
-
De Fougerolles, A.R.1
Manoharan, M.2
Meyers, R.3
Vornlocher, H.P.4
-
32
-
-
0038652203
-
The specifics of small interfering RNA specificity
-
Dillon A. The specifics of small interfering RNA specificity. Proc Natl Acad Sci USA. 2003;100:6289-91.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 6289-6291
-
-
Dillon, A.1
-
33
-
-
0037443089
-
SiRNAs can function as miRNAs
-
12600936 1:CAS:528:DC%2BD3sXhslCqtbo%3D
-
Doench JG, Petersen CP, Sharp PA. siRNAs can function as miRNAs. Genes Dev. 2003;17:438-42.
-
(2003)
Genes Dev
, vol.17
, pp. 438-442
-
-
Doench, J.G.1
Petersen, C.P.2
Sharp, P.A.3
-
34
-
-
0012756249
-
RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase
-
12000851
-
Donze O, Picard D. RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res. 2002;30:e46.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 46
-
-
Donze, O.1
Picard, D.2
-
35
-
-
2442669339
-
RNA interference
-
1:CAS:528:DC%2BD2cXntV2rtL0%3D
-
Downward J. RNA interference. Clin Rev. 2004;328:1245-8.
-
(2004)
Clin Rev
, vol.328
, pp. 1245-1248
-
-
Downward, J.1
-
36
-
-
1642400103
-
RNA interference: A practical approach
-
15047140 1:CAS:528:DC%2BD2cXisVSmur4%3D
-
Duxbury MS, Whang EE. RNA interference: a practical approach. J Surg Res. 2004;117:339-44.
-
(2004)
J Surg Res
, vol.117
, pp. 339-344
-
-
Duxbury, M.S.1
Whang, E.E.2
-
37
-
-
0037686295
-
Killing the messenger: Short RNAs that silence gene expression
-
1:CAS:528:DC%2BD3sXktFOns74%3D
-
Dykxhoorn DM, Novina CD, Sharp PA. Killing the messenger: short RNAs that silence gene expression. Nat Rev. 2003;4:457-67.
-
(2003)
Nat Rev
, vol.4
, pp. 457-467
-
-
Dykxhoorn, D.M.1
Novina, C.D.2
Sharp, P.A.3
-
38
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
11373684 1:CAS:528:DC%2BD3MXkt1ejt7Y%3D
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 2001;411:494-8.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
39
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
11157775 1:CAS:528:DC%2BD3MXhvVOjtbg%3D
-
Elbashir SM, Lendeckel W, Tuschi T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 2001;15:188-200.
-
(2001)
Genes Dev
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschi, T.3
-
40
-
-
0035803583
-
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
-
11726523 1:CAS:528:DC%2BD3MXptVaqurw%3D
-
Elbashir SM, Martinez J, Patkaniowska A, Lendeckel W, Tuschi T. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J. 2001;20:6877-88.
-
(2001)
EMBO J
, vol.20
, pp. 6877-6888
-
-
Elbashir, S.M.1
Martinez, J.2
Patkaniowska, A.3
Lendeckel, W.4
Tuschi, T.5
-
41
-
-
0036351317
-
Analysis of gene function in somatic mammalian cells using small interfering RNAs
-
12054897 1:CAS:528:DC%2BD38Xks1GhtLw%3D
-
Elbashir SM, Harborth J, Weber K, Tuschl T. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods. 2002;26:199-213.
-
(2002)
Methods
, vol.26
, pp. 199-213
-
-
Elbashir, S.M.1
Harborth, J.2
Weber, K.3
Tuschl, T.4
-
42
-
-
33646474112
-
Gene therapeutic approaches-transfer in vivo
-
16563557 1:CAS:528:DC%2BD28XksVaju7w%3D
-
Evans CH, Gouze E, Gouze JN, Robbins PD, Ghivizzani SC. Gene therapeutic approaches-transfer in vivo. Adv Drug Deliv Rev. 2006;58:243-58.
-
(2006)
Adv Drug Deliv Rev
, vol.58
, pp. 243-258
-
-
Evans, C.H.1
Gouze, E.2
Gouze, J.N.3
Robbins, P.D.4
Ghivizzani, S.C.5
-
43
-
-
0034485171
-
(Trans) gene silencing in plants: How many mechanisms?
-
1:CAS:528:DC%2BD3cXlsVymtrs%3D
-
Fagard M, Vaucheret H. (Trans) gene silencing in plants: How many mechanisms? Ann Rev Plant Physiol Plant Mol Biol. 2000;51:167-94.
-
(2000)
Ann Rev Plant Physiol Plant Mol Biol
, vol.51
, pp. 167-194
-
-
Fagard, M.1
Vaucheret, H.2
-
44
-
-
0029923638
-
Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors
-
8627803 1:CAS:528:DyaK28Xit1Ogsrk%3D
-
Ferrari FK, Samulski T, Shenk T, Samulski RJ. Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors. J Virol. 1996;70:3227-34.
-
(1996)
J Virol
, vol.70
, pp. 3227-3234
-
-
Ferrari, F.K.1
Samulski, T.2
Shenk, T.3
Samulski, R.J.4
-
45
-
-
0032545933
-
Potent of specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
9486653 1:CAS:528:DyaK1cXhtlCju74%3D
-
Fire A, Xu SQ, Montgomery MK, Kostas MK, Driver SE, Mello CC. Potent of specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 1998;391:806-11.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.Q.2
Montgomery, M.K.3
Kostas, M.K.4
Driver, S.E.5
Mello, C.C.6
-
46
-
-
0035964457
-
Cationized human serum albumin as a non-viral vector system for gene delivery? Characterization of complex formation with plasmid DNA and transfection efficiency
-
11489558 1:CAS:528:DC%2BD3MXlslant7c%3D
-
Fischer D, Bieber T, Brusselbach S, Elsasser HP, Kissel T. Cationized human serum albumin as a non-viral vector system for gene delivery? Characterization of complex formation with plasmid DNA and transfection efficiency. Int J Pharm. 2001;225:97-111.
-
(2001)
Int J Pharm
, vol.225
, pp. 97-111
-
-
Fischer, D.1
Bieber, T.2
Brusselbach, S.3
Elsasser, H.P.4
Kissel, T.5
-
47
-
-
0029558004
-
Cationic liposome-mediated gene transfer
-
8750010 1:CAS:528:DyaK2MXhtVSktr3J
-
Gao X, Huang L. Cationic liposome-mediated gene transfer. Gene Ther. 1995;2:710-22.
-
(1995)
Gene Ther
, vol.2
, pp. 710-722
-
-
Gao, X.1
Huang, L.2
-
48
-
-
0037418322
-
RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription
-
12594334 1:CAS:528:DC%2BD3sXitVait74%3D
-
Ge Q, McManus MT, Nguyen T, Shen CH, Sharp PA, Eisen HN, Chen J. RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci USA. 2003;100:2718-23.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2718-2723
-
-
Ge, Q.1
McManus, M.T.2
Nguyen, T.3
Shen, C.H.4
Sharp, P.A.5
Eisen, H.N.6
Chen, J.7
-
49
-
-
0035975647
-
Generation of a high capacity hybrid vector: Packaging of recombinant adenoassociated virus replicative intermediates in adenovirus capsids overcomes the limited cloning capacity of adenoassociated virus vectors
-
11601895 1:CAS:528:DC%2BD3MXnsFGjtLk%3D
-
Goncalves MAFV, Pau MG, de Vries AAF, Valerio D. Generation of a high capacity hybrid vector: packaging of recombinant adenoassociated virus replicative intermediates in adenovirus capsids overcomes the limited cloning capacity of adenoassociated virus vectors. Virology. 2001;288:236-46.
-
(2001)
Virology
, vol.288
, pp. 236-246
-
-
Goncalves, M.1
Pau, M.G.2
De Vries, A.A.F.3
Valerio, D.4
-
50
-
-
0036838585
-
Efficient generation and amplification of high-capacity adeno-associated virus/adenovirus hybrid vectors
-
12368316 1:CAS:528:DC%2BD38XnvFKjsr4%3D
-
Goncalves MAFV, van der Velde I, Janssen JM, Maassen BTH, Heemskerk EH, Opstelten DJE, Knaan-Shanzer S, Valerio D, de Vries AAF. Efficient generation and amplification of high-capacity adeno-associated virus/adenovirus hybrid vectors. J Virol. 2002;76:10734-74.
-
(2002)
J Virol
, vol.76
, pp. 10734-10774
-
-
Goncalves, M.1
Van Der Velde, I.2
Janssen, J.M.3
Maassen, B.T.H.4
Heemskerk, E.H.5
Opstelten, D.J.E.6
Knaan-Shanzer, S.7
Valerio, D.8
De Vries, A.A.F.9
-
51
-
-
0029315806
-
Methods for construction of adenovirus vectors
-
7552690 1:CAS:528:DyaK2MXntFSjsb0%3D
-
Graham FL, Prevec L. Methods for construction of adenovirus vectors. Mol Biotechnol. 1995;3:207-20.
-
(1995)
Mol Biotechnol
, vol.3
, pp. 207-220
-
-
Graham, F.L.1
Prevec, L.2
-
52
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
16724069 1:CAS:528:DC%2BD28XkvVyku7g%3D
-
Grimm D, Streetz KL, Jopling CL, Storm TA, Pandey K, Davis CR, Marion PL, Salazar FH, Kay MA. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature. 2006;441:537-41.
-
(2006)
Nature
, vol.441
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
Storm, T.A.4
Pandey, K.5
Davis, C.R.6
Marion, P.L.7
Salazar, F.H.8
Kay, M.A.9
-
53
-
-
33749873618
-
Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenes
-
16810314 1:CAS:528:DC%2BD28XhtVGktbrI
-
Gu W, Putral L, Hengst K, Minto K, Saunders NA, Leggatt G, McMillan NA. Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenes. Cancer Gene Ther. 2006;13:1023-32.
-
(2006)
Cancer Gene Ther
, vol.13
, pp. 1023-1032
-
-
Gu, W.1
Putral, L.2
Hengst, K.3
Minto, K.4
Saunders, N.A.5
Leggatt, G.6
McMillan, N.A.7
-
54
-
-
84934444079
-
SiRNA and shRNA as anticancer agents in a cervical cancer model
-
1:CAS:528:DC%2BD1cXls1KgsLo%3D
-
Gu W, Putral L, McMillan N. siRNA and shRNA as anticancer agents in a cervical cancer model. Methods in Mol Biol. 2008;442:159-72.
-
(2008)
Methods in Mol Biol
, vol.442
, pp. 159-172
-
-
Gu, W.1
Putral, L.2
McMillan, N.3
-
55
-
-
0033615491
-
A species of small antisense RNA in posttranscriptional gene silencing in plants
-
10542148 1:CAS:528:DyaK1MXntFaktbY%3D
-
Hamilton AJ, Baulcombe DC. A species of small antisense RNA in posttranscriptional gene silencing in plants. Science. 1999;286:950-2.
-
(1999)
Science
, vol.286
, pp. 950-952
-
-
Hamilton, A.J.1
Baulcombe, D.C.2
-
56
-
-
26944441255
-
Dicing and slicing: The core machinery of the RNA interference pathway
-
16214139 1:CAS:528:DC%2BD2MXhtFKmtbvF
-
Hammond SM. Dicing and slicing: the core machinery of the RNA interference pathway. FEBS Lett. 2005;579:5822-9.
-
(2005)
FEBS Lett
, vol.579
, pp. 5822-5829
-
-
Hammond, S.M.1
-
57
-
-
0036320633
-
The influence of inverted repeats on the production of small antisense RNAs involved in gene silencing
-
12172802 1:CAS:528:DC%2BD38XntFaksLw%3D
-
Han Y, Grierson D. The influence of inverted repeats on the production of small antisense RNAs involved in gene silencing. Mol Genet Genomics. 2002;267:629-35.
-
(2002)
Mol Genet Genomics
, vol.267
, pp. 629-635
-
-
Han, Y.1
Grierson, D.2
-
58
-
-
0037062951
-
RNA interference
-
12110901 1:CAS:528:DC%2BD38XltFGmu7Y%3D
-
Hannon GJ. RNA interference. Nature. 2002;418:244-51.
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
59
-
-
4644350944
-
Unlocking the potential of the human genome with RNA interference
-
15372045 1:CAS:528:DC%2BD2cXnsFaiu7s%3D
-
Hannon GJ, Rossi JJ. Unlocking the potential of the human genome with RNA interference. Nature. 2004;431:371-8.
-
(2004)
Nature
, vol.431
, pp. 371-378
-
-
Hannon, G.J.1
Rossi, J.J.2
-
60
-
-
0037021437
-
Small interfering RNA and gene silencing in transgenic mice and rats
-
12459495 1:CAS:528:DC%2BD38XovFGkt7Y%3D
-
Hasuwa H, Kaseda K, Einarsdottir T, Okabe M. Small interfering RNA and gene silencing in transgenic mice and rats. FEBS Lett. 2002;532:227-30.
-
(2002)
FEBS Lett
, vol.532
, pp. 227-230
-
-
Hasuwa, H.1
Kaseda, K.2
Einarsdottir, T.3
Okabe, M.4
-
61
-
-
84655167614
-
B2 or not B2: RNA interference reduces Macrobrachium rosenbergii nodavirus replication in redclaw crayfish (Cherax quadricarinatus)
-
Hayakijkosol O, Owens L. B2 or not B2: RNA interference reduces Macrobrachium rosenbergii nodavirus replication in redclaw crayfish (Cherax quadricarinatus). Aquaculture. 2012;326-329:40-5.
-
(2012)
Aquaculture
, vol.326-329
, pp. 40-45
-
-
Hayakijkosol, O.1
Owens, L.2
-
62
-
-
67649199387
-
Viral ubiquitin ligase WSSV222 is required for efficient white spot syndrome virus replication in shrimp
-
19264591 1:CAS:528:DC%2BD1MXmvFClsb0%3D
-
He F, Syed SM, Hameed ASS, Kwang J. Viral ubiquitin ligase WSSV222 is required for efficient white spot syndrome virus replication in shrimp. J Gen Virol. 2009;90:1483-90.
-
(2009)
J Gen Virol
, vol.90
, pp. 1483-1490
-
-
He, F.1
Syed, S.M.2
Hameed, A.S.S.3
Kwang, J.4
-
63
-
-
34347272315
-
Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA
-
17379663 1:CAS:528:DC%2BD2sXkt1KgsLY%3D
-
Heidel JD, Yu Z, Liu JY, Rele SM, Liang Y, Zeidan RK, Kornbrust DJ, Davis ME. Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA. Proc Natl Acad Sci USA. 2007;104:5715-21.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5715-5721
-
-
Heidel, J.D.1
Yu, Z.2
Liu, J.Y.3
Rele, S.M.4
Liang, Y.5
Zeidan, R.K.6
Kornbrust, D.J.7
Davis, M.E.8
-
64
-
-
0037348748
-
Progress and prospects: Naked DNA gene transfer and therapy
-
12621449 1:CAS:528:DC%2BD3sXhs1yhtrk%3D
-
Herweijer H, Wolff JA. Progress and prospects: naked DNA gene transfer and therapy. Gene Ther. 2003;10:453-8.
-
(2003)
Gene Ther
, vol.10
, pp. 453-458
-
-
Herweijer, H.1
Wolff, J.A.2
-
65
-
-
0041738964
-
Characterization of RNA interference in an Anopheles gambiae cell line
-
12915186 1:CAS:528:DC%2BD3sXmt1Wrs7o%3D
-
Hoa NT, Keene KM, Olsen KE, Zheng L. Characterization of RNA interference in an Anopheles gambiae cell line. Insect Biochem Mol Biol. 2003;33:949-57.
-
(2003)
Insect Biochem Mol Biol
, vol.33
, pp. 949-957
-
-
Hoa, N.T.1
Keene, K.M.2
Olsen, K.E.3
Zheng, L.4
-
66
-
-
0037089135
-
Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor
-
11937629 1:CAS:528:DC%2BD38Xjt1Ghsbk%3D
-
Holen T, Amarzguioui M, Wiiger MT, Babaie E, Prydz H. Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor. Nucleic Acids Res. 2002;30:1757-66.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 1757-1766
-
-
Holen, T.1
Amarzguioui, M.2
Wiiger, M.T.3
Babaie, E.4
Prydz, H.5
-
67
-
-
0021083306
-
Nucleotide sequence of the polyhedrin gene of Autographa californica nuclear polyhedrosis virus
-
18639177 1:CAS:528:DyaL2cXpslClsw%3D%3D
-
Hooft van Iddekinge BJL, Smith GE, Summers MD. Nucleotide sequence of the polyhedrin gene of Autographa californica nuclear polyhedrosis virus. Virology. 1983;131:561-5.
-
(1983)
Virology
, vol.131
, pp. 561-565
-
-
Hooft Van Iddekinge, B.J.L.1
Smith, G.E.2
Summers, M.D.3
-
68
-
-
7344259640
-
High efficiency gene transfer to the central nervous system of rodents and primates using herpes virus vectors lacking functional ICP27 and ICP34.5
-
10326038 1:CAS:528:DyaK1cXltFOgsbo%3D
-
Howard MK, Kershaw T, Gibb B, Storey N, MacLean AR, Zeng BY, Tel BC, Jenne P, Brown SM, Woolf CJ, Anderson PN, Coffin RS, Latchman DS. High efficiency gene transfer to the central nervous system of rodents and primates using herpes virus vectors lacking functional ICP27 and ICP34.5. Gene Ther. 1998;5:1137-47.
-
(1998)
Gene Ther
, vol.5
, pp. 1137-1147
-
-
Howard, M.K.1
Kershaw, T.2
Gibb, B.3
Storey, N.4
Maclean, A.R.5
Zeng, B.Y.6
Tel, B.C.7
Jenne, P.8
Brown, S.M.9
Woolf, C.J.10
Anderson, P.N.11
Coffin, R.S.12
Latchman, D.S.13
-
69
-
-
33748054817
-
RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system
-
16829204 1:CAS:528:DC%2BD28XptFCgsb8%3D
-
Howard KA, Rahbek UL, Liu X, Damgaard MB, Glud SZ, Andersen MO, Hovgaard MB, Schmitz A, Nyengaard JR, Besenbacher F, Kjems J. RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system. Mol Ther. 2006;14:476-84.
-
(2006)
Mol Ther
, vol.14
, pp. 476-484
-
-
Howard, K.A.1
Rahbek, U.L.2
Liu, X.3
Damgaard, M.B.4
Glud, S.Z.5
Andersen, M.O.6
Hovgaard, M.B.7
Schmitz, A.8
Nyengaard, J.R.9
Besenbacher, F.10
Kjems, J.11
-
70
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
12154197 1:CAS:528:DC%2BD38Xnt1ansLs%3D
-
Hutvagner G, Zamore PD. A microRNA in a multiple-turnover RNAi enzyme complex. Science. 2002;297:2056-60.
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvagner, G.1
Zamore, P.D.2
-
71
-
-
4744373229
-
Noise amidst the silence: Off-target effects of siRNAs?
-
15475108 1:CAS:528:DC%2BD2cXotlajs7s%3D
-
Jackson AL, Linsley PS. Noise amidst the silence: Off-target effects of siRNAs? Trends Genet. 2004;20:521-4.
-
(2004)
Trends Genet
, vol.20
, pp. 521-524
-
-
Jackson, A.L.1
Linsley, P.S.2
-
72
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
12754523 1:CAS:528:DC%2BD3sXktFSlu7c%3D
-
Jackson AL, Bartz SR, Schelter J, Kobayashi SV, Burchard J, Mao M, Li B, Cavet G, Linsley PS. Expression profiling reveals off-target gene regulation by RNAi. Nat Biotechnol. 2003;21:635-7.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 635-637
-
-
Jackson, A.L.1
Bartz, S.R.2
Schelter, J.3
Kobayashi, S.V.4
Burchard, J.5
Mao, M.6
Li, B.7
Cavet, G.8
Linsley, P.S.9
-
73
-
-
33745612464
-
Widespread siRNA 'off-target' transcript silencing mediated by seed region sequence complementarity
-
16682560 1:CAS:528:DC%2BD28Xms1Cqurw%3D
-
Jackson AL, Burchard J, Schelter J, Chau BN, Cleary M, Lim L, Linsley PS. Widespread siRNA 'off-target' transcript silencing mediated by seed region sequence complementarity. RNA. 2006;12:1179-87.
-
(2006)
RNA
, vol.12
, pp. 1179-1187
-
-
Jackson, A.L.1
Burchard, J.2
Schelter, J.3
Chau, B.N.4
Cleary, M.5
Lim, L.6
Linsley, P.S.7
-
74
-
-
35148845281
-
Effective RNAi-mediated gene silencing without interruption of the edogenous microRNA pathway
-
17898712 1:CAS:528:DC%2BD2sXhtFChurfL
-
John M, Constien R, Akinc A, Goldberg M, Moon YA, Spranger M, Hadwiger P, Soutschek J, Vorn-Locher HP, Manorharan M, Stoffel M, Langer R, Anderson DG, Horton JD, Koteliansky V, Bumcrot D. Effective RNAi-mediated gene silencing without interruption of the edogenous microRNA pathway. Nature. 2007;449:745-7.
-
(2007)
Nature
, vol.449
, pp. 745-747
-
-
John, M.1
Constien, R.2
Akinc, A.3
Goldberg, M.4
Moon, Y.A.5
Spranger, M.6
Hadwiger, P.7
Soutschek, J.8
Vorn-Locher, H.P.9
Manorharan, M.10
Stoffel, M.11
Langer, R.12
Anderson, D.G.13
Horton, J.D.14
Koteliansky, V.15
Bumcrot, D.16
-
75
-
-
22344454846
-
Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
-
1:CAS:528:DC%2BD2MXivFOhtLk%3D
-
Judge AD, Sood V, Shaw JR, Fang D, McClintock K, MacLachlan I. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nature Biotechnol. 2005;23:457-62.
-
(2005)
Nature Biotechnol
, vol.23
, pp. 457-462
-
-
Judge, A.D.1
Sood, V.2
Shaw, J.R.3
Fang, D.4
McClintock, K.5
Maclachlan, I.6
-
76
-
-
0037448540
-
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
-
Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, Gotta M, Kanapin A, Le Bot N, Moreno S, Sohrmann M, Welchman DP, Zipperlen P, Ahringer J. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature. 2003;421:237-321.
-
(2003)
Nature
, vol.421
, pp. 237-321
-
-
Kamath, R.S.1
Fraser, A.G.2
Dong, Y.3
Poulin, G.4
Durbin, R.5
Gotta, M.6
Kanapin, A.7
Le Bot, N.8
Moreno, S.9
Sohrmann, M.10
Welchman, D.P.11
Zipperlen, P.12
Ahringer, J.13
-
78
-
-
0037327444
-
SiRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells
-
12560494 1:CAS:528:DC%2BD3sXit1aqt7k%3D
-
Kawasaki H, Suyama E, Iyo M, Taira K. siRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells. Nucleic Acids Res. 2003;31:981-7.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 981-987
-
-
Kawasaki, H.1
Suyama, E.2
Iyo, M.3
Taira, K.4
-
79
-
-
0035135747
-
Viral vectors for gene therapy: The art of turning infectious agents into vehicles of therapeutics
-
11135613 1:CAS:528:DC%2BD3MXmvV2nsw%3D%3D
-
Kay MA, Glorioso JC, Naldini L. Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics. Nat Med. 2001;7:33-40.
-
(2001)
Nat Med
, vol.7
, pp. 33-40
-
-
Kay, M.A.1
Glorioso, J.C.2
Naldini, L.3
-
80
-
-
0032443021
-
Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway
-
9875855 1:CAS:528:DyaK1MXjslyktw%3D%3D
-
Kennerdell JR, Carthew RW. Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell. 1998;95:1017-26.
-
(1998)
Cell
, vol.95
, pp. 1017-1026
-
-
Kennerdell, J.R.1
Carthew, R.W.2
-
81
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
-
11641272 1:CAS:528:DC%2BD3MXnvVWksLY%3D
-
Ketting RF, Fischer SEJ, Bernstein E, Sijen T, Hannon GJ, Plasterk RHA. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 2001;15:2654-9.
-
(2001)
Genes Dev
, vol.15
, pp. 2654-2659
-
-
Ketting, R.F.1
Fischer, S.E.J.2
Bernstein, E.3
Sijen, T.4
Hannon, G.J.5
Plasterk, R.H.A.6
-
82
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
14567918 1:CAS:528:DC%2BD3sXosFCqsLs%3D
-
Khvorova A, Reynolds A, Jayasena SD. Functional siRNAs and miRNAs exhibit strand bias. Cell. 2003;115:209-16.
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
83
-
-
13844281898
-
Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
-
15619617
-
Kim DH, Behlke MA, Rose SD, Chang MS, Choi S, Rossi JJ. Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy. Nat Biotechnol. 2004;23:222-6.
-
(2004)
Nat Biotechnol
, vol.23
, pp. 222-226
-
-
Kim, D.H.1
Behlke, M.A.2
Rose, S.D.3
Chang, M.S.4
Choi, S.5
Rossi, J.J.6
-
84
-
-
1542306855
-
Interferon induction by siRNAs and ssRNAs synthesised by phage polymerase
-
14990954 1:CAS:528:DC%2BD2cXhs1Wms7k%3D
-
Kim DH, Longo M, Han Y, Lundberg P, Cantin E, Rossi JJ. Interferon induction by siRNAs and ssRNAs synthesised by phage polymerase. Nat Biotechnol. 2004;22:321-5.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 321-325
-
-
Kim, D.H.1
Longo, M.2
Han, Y.3
Lundberg, P.4
Cantin, E.5
Rossi, J.J.6
-
85
-
-
0031019819
-
Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors
-
9037069 1:CAS:528:DyaK2sXhtlOit7g%3D
-
Koeberl DD, Alexander IE, Halbert CL, Russell DW, Miller AD. Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors. Proc Natl Acad Sci USA. 1997;94:1426-31.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1426-1431
-
-
Koeberl, D.D.1
Alexander, I.E.2
Halbert, C.L.3
Russell, D.W.4
Miller, A.D.5
-
86
-
-
12144289381
-
Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs
-
15016866
-
Kronke J, Kittler R, Buchholz F, Windisch MP, Pietschmann T, Bartenschlager R, Frese M. Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs. J Virol. 2004;78:3436-46.
-
(2004)
J Virol
, vol.78
, pp. 3436-3446
-
-
Kronke, J.1
Kittler, R.2
Buchholz, F.3
Windisch, M.P.4
Pietschmann, T.5
Bartenschlager, R.6
Frese, M.7
-
87
-
-
0029616020
-
Development of cell lines capable of complementing E1, E4, and protein IX defective adenovirus type 5 mutants
-
8664382 1:CAS:528:DyaK28XptlSqtA%3D%3D
-
Krougliak V, Graham FL. Development of cell lines capable of complementing E1, E4, and protein IX defective adenovirus type 5 mutants. Hum Gene Ther. 1995;6:1575-86.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 1575-1586
-
-
Krougliak, V.1
Graham, F.L.2
-
88
-
-
0037370612
-
A new hybrid system capable of efficient lentiviral vector production and stable gene transfer mediated by a single helper-dependent adenoviral vector
-
Kubo S, Mitani K. A new hybrid system capable of efficient lentiviral vector production and stable gene transfer mediated by a single helper-dependent adenoviral vector. J Virol. 2003;77:2694-971.
-
(2003)
J Virol
, vol.77
, pp. 2694-2971
-
-
Kubo, S.1
Mitani, K.2
-
89
-
-
0033951293
-
Gene expression after intrarenal injection of plasmid DNA in the rat
-
10684368 1:STN:280:DC%2BD3c7kvVCisw%3D%3D
-
Kuemmerle NB, Lin PS, Krieg RJ, Lin KC, Ward KP, Chan JCM. Gene expression after intrarenal injection of plasmid DNA in the rat. Pediatr Nephrol. 2000;14:152-7.
-
(2000)
Pediatr Nephrol
, vol.14
, pp. 152-157
-
-
Kuemmerle, N.B.1
Lin, P.S.2
Krieg, R.J.3
Lin, K.C.4
Ward, K.P.5
Chan, J.C.M.6
-
90
-
-
34447114618
-
Transvascular delivery of small interfering RNA to the central nervous system
-
Kumar P, Wu H, McBride JL, Jung KE, Kim MH, Davidson BL, Lee SK, Shankar P, Manjunath N. Transvascular delivery of small interfering RNA to the central nervous system. Nature. 2007;448:505-14.
-
(2007)
Nature
, vol.448
, pp. 505-514
-
-
Kumar, P.1
Wu, H.2
McBride, J.L.3
Jung, K.E.4
Kim, M.H.5
Davidson, B.L.6
Lee, S.K.7
Shankar, P.8
Manjunath, N.9
-
91
-
-
0021682191
-
Nucleotide sequence of the p10 polypeptide gene of Autographa californica nuclear polyhedrosis virus
-
18639833 1:CAS:528:DyaL2MXptVKntg%3D%3D
-
Kuzio J, Rohel DZ, Curry CJ, Krebs A, Carstens EB, Faulkner P. Nucleotide sequence of the p10 polypeptide gene of Autographa californica nuclear polyhedrosis virus. Virology. 1984;139:414-8.
-
(1984)
Virology
, vol.139
, pp. 414-418
-
-
Kuzio, J.1
Rohel, D.Z.2
Curry, C.J.3
Krebs, A.4
Carstens, E.B.5
Faulkner, P.6
-
92
-
-
42649085361
-
The use of insects as a bioassay for Penaeus merguiensis densovirus (PmergDNV)
-
La Fauce KA, Owens L. The use of insects as a bioassay for Penaeus merguiensis densovirus (PmergDNV). J Invert Pathol. 2008;98:1-6.
-
(2008)
J Invert Pathol
, vol.98
, pp. 1-6
-
-
La Fauce, K.A.1
Owens, L.2
-
93
-
-
58649123583
-
RNA interference reduces PmergDNV expression and replication in an in vivo cricket model
-
La Fauce KA, Owens L. RNA interference reduces PmergDNV expression and replication in an in vivo cricket model. J Invert Pathol. 2009;100:111-5.
-
(2009)
J Invert Pathol
, vol.100
, pp. 111-115
-
-
La Fauce, K.A.1
Owens, L.2
-
94
-
-
0033768371
-
Double-stranded RNA interference in Trypanosoma burcei using head-to-head promoters
-
11087917 1:CAS:528:DC%2BD3cXot12qtr0%3D
-
LaCount D, Bruse S, Hill KL, Donelson JE. Double-stranded RNA interference in Trypanosoma burcei using head-to-head promoters. Mol Biochem Parasitol. 2000;111:67-76.
-
(2000)
Mol Biochem Parasitol
, vol.111
, pp. 67-76
-
-
Lacount, D.1
Bruse, S.2
Hill, K.L.3
Donelson, J.E.4
-
95
-
-
14744297069
-
Intracellular routing of plasmid DNA during non-viral gene transfer
-
15757759 1:CAS:528:DC%2BD2MXitFertbk%3D
-
Lechardeur D, Verkman AS, Lukacs GL. Intracellular routing of plasmid DNA during non-viral gene transfer. Adv Drug Deliv Rev. 2005;57:755-67.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 755-767
-
-
Lechardeur, D.1
Verkman, A.S.2
Lukacs, G.L.3
-
96
-
-
33644840901
-
SiRNA-getting the message out
-
16442784 1:CAS:528:DC%2BD28Xit1Chtrk%3D
-
Lee SH, Shinko PJ. siRNA-getting the message out. Eur J Pharm Sci. 2006;27:401-10.
-
(2006)
Eur J Pharm Sci
, vol.27
, pp. 401-410
-
-
Lee, S.H.1
Shinko, P.J.2
-
97
-
-
0034467912
-
A baculovirus superinfection system: Efficient vehicle for gene transfer into Drosophila S2 cells
-
11090187 1:STN:280:DC%2BD3M%2FotlSnug%3D%3D
-
Lee DF, Chen CC, Hsu TA, Juang JL. A baculovirus superinfection system: efficient vehicle for gene transfer into Drosophila S2 cells. J Virol. 2000;74:11873-80.
-
(2000)
J Virol
, vol.74
, pp. 11873-11880
-
-
Lee, D.F.1
Chen, C.C.2
Hsu, T.A.3
Juang, J.L.4
-
98
-
-
17144401470
-
Novel molecular approaches to cystic fibrosis gene therapy
-
15656784 1:CAS:528:DC%2BD2MXisFWgsbc%3D
-
Lee TWR, Matthews DA, Blair GE. Novel molecular approaches to cystic fibrosis gene therapy. Biochem J. 2005;387:1-15.
-
(2005)
Biochem J
, vol.387
, pp. 1-15
-
-
Lee, T.W.R.1
Matthews, D.A.2
Blair, G.E.3
-
99
-
-
0033533669
-
Virus treatment questioned after gene therapy death
-
10524611 1:CAS:528:DyaK1MXmvFCns7k%3D
-
Lehrman S. Virus treatment questioned after gene therapy death. Nature. 1999;401:517-8.
-
(1999)
Nature
, vol.401
, pp. 517-518
-
-
Lehrman, S.1
-
100
-
-
0022530761
-
Nucleotide sequencing and transcriptional mapping of the Orgyia pseudotsugata multicapsid nuclear polyhedrosis virus p10 gene
-
3526709 1:CAS:528:DyaL28Xls1Gqtbo%3D
-
Leisy DJ, Rohrmann GF, Nesson M, Beaudreau GS. Nucleotide sequencing and transcriptional mapping of the Orgyia pseudotsugata multicapsid nuclear polyhedrosis virus p10 gene. Virology. 1986;153:157-67.
-
(1986)
Virology
, vol.153
, pp. 157-167
-
-
Leisy, D.J.1
Rohrmann, G.F.2
Nesson, M.3
Beaudreau, G.S.4
-
101
-
-
0026654682
-
Human immunodeficiency virus infection of cells arrested in the cell cycle
-
1322294 1:CAS:528:DyaK38XlsV2it70%3D
-
Lewis P, Hensel M, Emerman M. Human immunodeficiency virus infection of cells arrested in the cell cycle. EMBO J. 1992;11:3053-8.
-
(1992)
EMBO J
, vol.11
, pp. 3053-3058
-
-
Lewis, P.1
Hensel, M.2
Emerman, M.3
-
102
-
-
0035313137
-
Viral suppressors of RNA silencing
-
11287229 1:CAS:528:DC%2BD3MXjt1Olu7w%3D
-
Li WX, Ding SW. Viral suppressors of RNA silencing. Curr Opin Biotechnol. 2001;12:150-4.
-
(2001)
Curr Opin Biotechnol
, vol.12
, pp. 150-154
-
-
Li, W.X.1
Ding, S.W.2
-
103
-
-
0037123630
-
Induction and suppression of RNA silencing by an animal virus
-
12016316 1:CAS:528:DC%2BD38Xjsl2qurg%3D
-
Li HW, Li WX, Ding SW. Induction and suppression of RNA silencing by an animal virus. Science. 2002;296:1319-21.
-
(2002)
Science
, vol.296
, pp. 1319-1321
-
-
Li, H.W.1
Li, W.X.2
Ding, S.W.3
-
104
-
-
0036096778
-
B56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster
-
11997504 1:CAS:528:DC%2BD38XjslWlsbc%3D
-
Li X, Scuderi A, Letsou A, Virshup DM. B56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster. Mol Cell Biol. 2002;22:3674-84.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3674-3684
-
-
Li, X.1
Scuderi, A.2
Letsou, A.3
Virshup, D.M.4
-
105
-
-
0035043465
-
Multiple immediate-early gene deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system
-
11287583 1:CAS:528:DC%2BD3MXivFOktLc%3D
-
Lilley CE, Groutsi F, Han Z, Palmer JA, Anderson PN, Latchman DS, Coffin RS. Multiple immediate-early gene deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system. J Virol. 2001;75:4343-56.
-
(2001)
J Virol
, vol.75
, pp. 4343-4356
-
-
Lilley, C.E.1
Groutsi, F.2
Han, Z.3
Palmer, J.A.4
Anderson, P.N.5
Latchman, D.S.6
Coffin, R.S.7
-
106
-
-
13944282215
-
Microarray analysis shows that some microRNAs do downregulate large numbers of target mRNAs
-
15685193 1:CAS:528:DC%2BD2MXhtleqsLs%3D
-
Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM. Microarray analysis shows that some microRNAs do downregulate large numbers of target mRNAs. Nature. 2005;433:769-73.
-
(2005)
Nature
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
Grimson, A.4
Schelter, J.M.5
Castle, J.6
Bartel, D.P.7
Linsley, P.S.8
Johnson, J.M.9
-
107
-
-
23344438420
-
SiRNA-mediated off-target gene silencing triggered by a 7 nt complementation
-
16091630 1:CAS:528:DC%2BD2MXovVKqt7s%3D
-
Lin X, Ruan X, Anderson MG, McDowell JA, Kroeger PE, Fesik SW, Shen Y. siRNA-mediated off-target gene silencing triggered by a 7 nt complementation. Nucleic Acids Res. 2005;33:4527-35.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 4527-4535
-
-
Lin, X.1
Ruan, X.2
Anderson, M.G.3
McDowell, J.A.4
Kroeger, P.E.5
Fesik, S.W.6
Shen, Y.7
-
108
-
-
33645285291
-
Stable RNA interference in Spodoptera frugiperda cells by a DNA vector-based method
-
16555012 1:CAS:528:DC%2BD28XislCqur8%3D
-
Lin CC, Hsu JTA, Huang KL, Tang HK, Lai YL. Stable RNA interference in Spodoptera frugiperda cells by a DNA vector-based method. Biotechnol Lett. 2006;28:271-7.
-
(2006)
Biotechnol Lett
, vol.28
, pp. 271-277
-
-
Lin, C.C.1
Hsu, J.T.A.2
Huang, K.L.3
Tang, H.K.4
Lai, Y.L.5
-
109
-
-
0035798399
-
RNAi as random degradative PCR: SiRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs
-
11701121 1:CAS:528:DC%2BD3MXosVKhsLY%3D
-
Lipardi C, Wei Q, Paterson BM. RNAi as random degradative PCR: siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs. Cell. 2001;107:297-307.
-
(2001)
Cell
, vol.107
, pp. 297-307
-
-
Lipardi, C.1
Wei, Q.2
Paterson, B.M.3
-
110
-
-
0037122695
-
Development of non-viral vectors for systemic gene delivery
-
11772466 1:CAS:528:DC%2BD3MXptlait7w%3D
-
Liu F, Huang L. Development of non-viral vectors for systemic gene delivery. J Control Release. 2002;78:259-66.
-
(2002)
J Control Release
, vol.78
, pp. 259-266
-
-
Liu, F.1
Huang, L.2
-
111
-
-
0037790710
-
Molecular basis of the inflammatory response to adenovirus vectors
-
12756413 1:CAS:528:DC%2BD3sXjvVagt74%3D
-
Liu Q, Muruve DA. Molecular basis of the inflammatory response to adenovirus vectors. Gene Ther. 2003;10:935-40.
-
(2003)
Gene Ther
, vol.10
, pp. 935-940
-
-
Liu, Q.1
Muruve, D.A.2
-
112
-
-
33750306792
-
Antilipopolysaccharide factor interferes with white spot syndrome virus replication in vitro and in vivo in the crayfish Pacifastacus leniusculus
-
17041217 1:CAS:528:DC%2BD28XhtFygsLnJ
-
Liu H, Jiravanichpaisal P, Soderhall I, Cerenius L, Soderhall K. Antilipopolysaccharide factor interferes with white spot syndrome virus replication in vitro and in vivo in the crayfish Pacifastacus leniusculus. J Virol. 2006;80:10365-71.
-
(2006)
J Virol
, vol.80
, pp. 10365-10371
-
-
Liu, H.1
Jiravanichpaisal, P.2
Soderhall, I.3
Cerenius, L.4
Soderhall, K.5
-
114
-
-
79952737207
-
Interaction between white spot syndrome virus VP26 and hemocyte membrane of shrimp Fenneropenaeus chinensis
-
Liu B, Tang X, Zhan W. Interaction between white spot syndrome virus VP26 and hemocyte membrane of shrimp Fenneropenaeus chinensis. Aquaculture. 2011;314:13-7.
-
(2011)
Aquaculture
, vol.314
, pp. 13-17
-
-
Liu, B.1
Tang, X.2
Zhan, W.3
-
115
-
-
0036468677
-
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
-
11786607 1:CAS:528:DC%2BD38XhtFemt70%3D
-
Lois C, Hong EJ, Pease S, Brown EJ, Baltimore D. Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science. 2002;295:868-72.
-
(2002)
Science
, vol.295
, pp. 868-872
-
-
Lois, C.1
Hong, E.J.2
Pease, S.3
Brown, E.J.4
Baltimore, D.5
-
116
-
-
2442679207
-
Structural basis for overhang-specific small-interfering RNA recognition by the PAZ domain
-
15152257 1:CAS:528:DC%2BD2cXktVOqtb8%3D
-
Ma JB, Ye K, Patel DJ. Structural basis for overhang-specific small-interfering RNA recognition by the PAZ domain. Nature. 2004;429:318-22.
-
(2004)
Nature
, vol.429
, pp. 318-322
-
-
Ma, J.B.1
Ye, K.2
Patel, D.J.3
-
117
-
-
0024488843
-
Expression of foreign genes in insects using baculovirus vectors
-
2648970 1:CAS:528:DyaL1MXht12gtr4%3D
-
Maeda S. Expression of foreign genes in insects using baculovirus vectors. Annu Rev Entomol. 1989;34:351-72.
-
(1989)
Annu Rev Entomol
, vol.34
, pp. 351-372
-
-
Maeda, S.1
-
118
-
-
0036049784
-
Double-stranded RNA-mediated gene silencing of cysteine proteases (falcipain-1 and -2) of Plasmodium falciparum
-
12207693 1:CAS:528:DC%2BD38XntFGktLk%3D
-
Malhotra P, Dasaradhi PVN, Kumar A, Mohammed A, Agrawal N, Bhatnager RK, Chauhan VS. Double-stranded RNA-mediated gene silencing of cysteine proteases (falcipain-1 and -2) of Plasmodium falciparum. Mol Microbiol. 2002;45:1245-54.
-
(2002)
Mol Microbiol
, vol.45
, pp. 1245-1254
-
-
Malhotra, P.1
Dasaradhi, P.V.N.2
Kumar, A.3
Mohammed, A.4
Agrawal, N.5
Bhatnager, R.K.6
Chauhan, V.S.7
-
119
-
-
0033579358
-
Gene therapy death prompts review of adenovirus vector
-
10636774 1:CAS:528:DC%2BD3cXjs1Sq
-
Marshall E. Gene therapy death prompts review of adenovirus vector. Science. 1999;286:2244-5.
-
(1999)
Science
, vol.286
, pp. 2244-2245
-
-
Marshall, E.1
-
120
-
-
0000213492
-
Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants
-
16453872 1:CAS:528:DyaL1MXhvVOhtrc%3D
-
Matzke MA, Primig M, Trnovsky J, Matzke AJ. Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants. EMBO J. 1989;8:643-9.
-
(1989)
EMBO J
, vol.8
, pp. 643-649
-
-
Matzke, M.A.1
Primig, M.2
Trnovsky, J.3
Matzke, A.J.4
-
121
-
-
0038023197
-
Inhibition of hepatitis B virus in mice by RNA interference
-
12740585 1:CAS:528:DC%2BD3sXktFSlu7w%3D
-
McCaffrey AP, Nakai H, Pandey K, Huang Z, Salazar FH, Xu H, Weiland SF, Marion PL, Kay MA. Inhibition of hepatitis B virus in mice by RNA interference. Nat Biotechnol. 2003;21:639-44.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 639-644
-
-
McCaffrey, A.P.1
Nakai, H.2
Pandey, K.3
Huang, Z.4
Salazar, F.H.5
Xu, H.6
Weiland, S.F.7
Marion, P.L.8
Kay, M.A.9
-
122
-
-
41149161324
-
A potential treatment for pandemic influenza using siRNAs targeting conserved regions of influenza A
-
18294101 1:CAS:528:DC%2BD1cXitlems7s%3D
-
McSwiggen JA, Seth S. A potential treatment for pandemic influenza using siRNAs targeting conserved regions of influenza A. Expert Opin Biol Ther. 2008;8:299-313.
-
(2008)
Expert Opin Biol Ther
, vol.8
, pp. 299-313
-
-
McSwiggen, J.A.1
Seth, S.2
-
123
-
-
14744290978
-
Physical methods for gene transfer: Improving the kinetics of gene delivery into cells
-
15757758 1:CAS:528:DC%2BD2MXitFertbg%3D
-
Mehier-Humbert S, Guy RH. Physical methods for gene transfer: improving the kinetics of gene delivery into cells. Adv Drug Deliv Rev. 2005;57:733-53.
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 733-753
-
-
Mehier-Humbert, S.1
Guy, R.H.2
-
124
-
-
30344485789
-
RNA silencing of single and multiple members in a gene family of rice
-
16172097 1:CAS:528:DC%2BD2MXps12lsrg%3D
-
Miki D, Itoh R, Shimamoto K. RNA silencing of single and multiple members in a gene family of rice. Plant Physiol. 2005;138:1903-13.
-
(2005)
Plant Physiol
, vol.138
, pp. 1903-1913
-
-
Miki, D.1
Itoh, R.2
Shimamoto, K.3
-
125
-
-
0024152865
-
Baculoviruss as gene expression vectors
-
1:CAS:528:DyaL1cXmt1entrc%3D
-
Miller LK. Baculoviruss as gene expression vectors. Ann Rev Microbiol. 1988;42:177-99.
-
(1988)
Ann Rev Microbiol
, vol.42
, pp. 177-199
-
-
Miller, L.K.1
-
126
-
-
1942499451
-
Improving the efficiency of RNA interference in mammals
-
15143318 1:CAS:528:DC%2BD2cXjsl2iu70%3D
-
Mittal V. Improving the efficiency of RNA interference in mammals. Nat Rev Genet. 2004;5:355-65.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 355-365
-
-
Mittal, V.1
-
127
-
-
0036210482
-
Novel integrating adenoviral/retroviral hybrid vector for gene therapy
-
11936973 1:CAS:528:DC%2BD38Xjt1Grsrg%3D
-
Murphy SJ, Chong H, Bell S, Diaz RM, Vile RG. Novel integrating adenoviral/retroviral hybrid vector for gene therapy. Hum Gene Ther. 2002;13:745-60.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 745-760
-
-
Murphy, S.J.1
Chong, H.2
Bell, S.3
Diaz, R.M.4
Vile, R.G.5
-
128
-
-
0029993858
-
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
-
8876144 1:CAS:528:DyaK28Xmtlags7c%3D
-
Naldini L, Blomer U, Gage FH, Trono D, Verma IM. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci USA. 1996;93:11382-8.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11382-11388
-
-
Naldini, L.1
Blomer, U.2
Gage, F.H.3
Trono, D.4
Verma, I.M.5
-
129
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
8602510 1:CAS:528:DyaK28Xit1KqsLw%3D
-
Naldini L, Blomer U, Gallay P, Ory D, Mulligan R, Gage FH, Verma IM, Trono D. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science. 1996;272:263-7.
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
Blomer, U.2
Gallay, P.3
Ory, D.4
Mulligan, R.5
Gage, F.H.6
Verma, I.M.7
Trono, D.8
-
130
-
-
0001359591
-
Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans
-
12354959 1:CAS:528:DyaK3cXkvFalu7c%3D
-
Napoli C, Lemieux C, Jorgensen R. Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans. Plant Cell. 1990;2:279-89.
-
(1990)
Plant Cell
, vol.2
, pp. 279-289
-
-
Napoli, C.1
Lemieux, C.2
Jorgensen, R.3
-
131
-
-
0033780376
-
Effective targeted gene 'knockdown' in zebrafish
-
Nasevicuis A, Ekker SC. Effective targeted gene 'knockdown' in zebrafish. Nat Genet. 2000;26:216-20.
-
(2000)
Nat Genet
, vol.26
, pp. 216-220
-
-
Nasevicuis, A.1
Ekker, S.C.2
-
132
-
-
73349101856
-
Dynamic evolution of immune system regulators: The history of the interferon regulatory factor family
-
19638535 1:CAS:528:DC%2BD1MXht1Oqs7fJ
-
Nehyba J, Hrdlickova R, Bose HR. Dynamic evolution of immune system regulators: the history of the interferon regulatory factor family. Mol Biol Evol. 2009;26:2539-50.
-
(2009)
Mol Biol Evol
, vol.26
, pp. 2539-2550
-
-
Nehyba, J.1
Hrdlickova, R.2
Bose, H.R.3
-
133
-
-
3142615372
-
The RNAi revolution
-
15241403 1:CAS:528:DC%2BD2cXlsVCqu7s%3D
-
Novina CD, Sharp PA. The RNAi revolution. Nature. 2004;430:161-4.
-
(2004)
Nature
, vol.430
, pp. 161-164
-
-
Novina, C.D.1
Sharp, P.A.2
-
134
-
-
0035798415
-
ATP requirements and small interfering RNA structure in the RNA interference pathway
-
11701122 1:CAS:528:DC%2BD3MXosVKhsLc%3D
-
Nykanen A, Haley B, Zamore PD. ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell. 2001;107:309-21.
-
(2001)
Cell
, vol.107
, pp. 309-321
-
-
Nykanen, A.1
Haley, B.2
Zamore, P.D.3
-
135
-
-
79959586413
-
Inhibition of Taura syndrome virus replication in Litopenaeus vannamei through silencing the LvRab7 gene using double-stranded RNA
-
21347841 1:CAS:528:DC%2BC3MXotVaqs70%3D
-
Ongvarrasopone C, Saejia P, Chanasakulniyom M, Panyim S. Inhibition of Taura syndrome virus replication in Litopenaeus vannamei through silencing the LvRab7 gene using double-stranded RNA. Arch Virol. 2011;156:1117-23.
-
(2011)
Arch Virol
, vol.156
, pp. 1117-1123
-
-
Ongvarrasopone, C.1
Saejia, P.2
Chanasakulniyom, M.3
Panyim, S.4
-
136
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
11959843 1:CAS:528:DC%2BD38Xjt1Gktbs%3D
-
Paddison PJ, Caudy AA, Bernstein E, Hannon GJ, Conklin DS. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 2002;16:948-58.
-
(2002)
Genes Dev
, vol.16
, pp. 948-958
-
-
Paddison, P.J.1
Caudy, A.A.2
Bernstein, E.3
Hannon, G.J.4
Conklin, D.S.5
-
137
-
-
0037022382
-
Stable suppression of gene expression by RNAi in mammalian cells
-
11818553 1:CAS:528:DC%2BD38Xht1ClsLo%3D
-
Paddison PJ, Caudy AA, Hannon GJ. Stable suppression of gene expression by RNAi in mammalian cells. Proc Natl Acad Sci USA. 2002;99:1443-8.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 1443-1448
-
-
Paddison, P.J.1
Caudy, A.A.2
Hannon, G.J.3
-
138
-
-
0031903006
-
Site-specific integration in mammalian cells mediated by a new hybrid baculovirus- adeno-associated virus vector
-
9573272 1:CAS:528:DyaK1cXjtVeiurY%3D
-
Palombo F, Monciotti A, Recchia A, Cortese R, Ciliberto G, La Monica N. Site-specific integration in mammalian cells mediated by a new hybrid baculovirus- adeno-associated virus vector. J Virol. 1998;72:5025-34.
-
(1998)
J Virol
, vol.72
, pp. 5025-5034
-
-
Palombo, F.1
Monciotti, A.2
Recchia, A.3
Cortese, R.4
Ciliberto, G.5
La Monica, N.6
-
139
-
-
0034757613
-
Distinct roles for RDE-1 and RDE-4 during RNA interference in Caenorhabditis elegans
-
11680844 1:CAS:528:DC%2BD3MXnvFSkurs%3D
-
Parrish S, Fire A. Distinct roles for RDE-1 and RDE-4 during RNA interference in Caenorhabditis elegans. RNA. 2001;7:1397-402.
-
(2001)
RNA
, vol.7
, pp. 1397-1402
-
-
Parrish, S.1
Fire, A.2
-
140
-
-
23744499649
-
Evidence implying only unprimed RdRP activity during transitive gene silencing in plants
-
16021340 1:CAS:528:DC%2BD2MXmt1Wnsrk%3D
-
Petersen BO, Albrechtsen M. Evidence implying only unprimed RdRP activity during transitive gene silencing in plants. Plant Mol Biol. 2005;58:575-83.
-
(2005)
Plant Mol Biol
, vol.58
, pp. 575-583
-
-
Petersen, B.O.1
Albrechtsen, M.2
-
141
-
-
0035778751
-
Gene therapy: Promises and problems
-
11701648 1:CAS:528:DC%2BD3MXos1antb0%3D
-
Pfeifer A, Verma IM. Gene therapy: promises and problems. Annu Rev Genomics Hum Genet. 2001;2:177-211.
-
(2001)
Annu Rev Genomics Hum Genet
, vol.2
, pp. 177-211
-
-
Pfeifer, A.1
Verma, I.M.2
-
142
-
-
33846169452
-
Intravenous delivery of anti-RhoA small interfering RNA (siRNA) loaded in nanoparticles of chitosan in mice: Safety and efficacy in xenografted aggressive breast cancer
-
17007568 1:CAS:528:DC%2BD28XhtVGgsr%2FL
-
Pille JY, Li H, Blot E, Bertrand JR, Pritchard LL, Opolan P, Makisemnko A, Lu H, Vannier JP, Soria J, Malvy C, Soria C. Intravenous delivery of anti-RhoA small interfering RNA (siRNA) loaded in nanoparticles of chitosan in mice: safety and efficacy in xenografted aggressive breast cancer. Hum Gene Ther. 2006;17:1019-26.
-
(2006)
Hum Gene Ther
, vol.17
, pp. 1019-1026
-
-
Pille, J.Y.1
Li, H.2
Blot, E.3
Bertrand, J.R.4
Pritchard, L.L.5
Opolan, P.6
Makisemnko, A.7
Lu, H.8
Vannier, J.P.9
Soria, J.10
Malvy, C.11
Soria, C.12
-
143
-
-
79952737589
-
Improved preventative and curative effects of YHV infection in Penaeus monodon by a combination of two double stranded RNAs
-
1:CAS:528:DC%2BC3MXjs1yqtLw%3D
-
Posiri P, Ongvarrasopone C, Panyim S. Improved preventative and curative effects of YHV infection in Penaeus monodon by a combination of two double stranded RNAs. Aquaculture. 2011;314:34-8.
-
(2011)
Aquaculture
, vol.314
, pp. 34-38
-
-
Posiri, P.1
Ongvarrasopone, C.2
Panyim, S.3
-
144
-
-
0032580453
-
Polycation-DNA complexes for gene delivery: A comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids
-
9741937 1:CAS:528:DyaK1cXitVCjsLY%3D
-
Pouton CW, Lucas P, Thomas BJ, Uduehi AN, Milroy DA, Moss SH. Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids. J Control Release. 1998;53:289-99.
-
(1998)
J Control Release
, vol.53
, pp. 289-299
-
-
Pouton, C.W.1
Lucas, P.2
Thomas, B.J.3
Uduehi, A.N.4
Milroy, D.A.5
Moss, S.H.6
-
145
-
-
0034650936
-
Delivery of DNA to early embryos of the Kuruma prawn Penaeus japonicas
-
1:CAS:528:DC%2BD3cXns1On
-
Preston NP, Baule VJ, Leopold R, Henderling J, Atkinson S, Whyard S. Delivery of DNA to early embryos of the Kuruma prawn Penaeus japonicas. Aquaculture. 2000;181:225-34.
-
(2000)
Aquaculture
, vol.181
, pp. 225-234
-
-
Preston, N.P.1
Baule, V.J.2
Leopold, R.3
Henderling, J.4
Atkinson, S.5
Whyard, S.6
-
146
-
-
26944443659
-
Suppressors of RNA silencing encoded by plant viruses and their role in viral infection
-
16162340 1:CAS:528:DC%2BD2MXhtFKmtbnI
-
Qu F, Morris TJ. Suppressors of RNA silencing encoded by plant viruses and their role in viral infection. FEBS Lett. 2005;579:5958-64.
-
(2005)
FEBS Lett
, vol.579
, pp. 5958-5964
-
-
Qu, F.1
Morris, T.J.2
-
147
-
-
54049130781
-
Maintaining the silence: Reflections on long-term RNAi
-
18620073 1:CAS:528:DC%2BD1cXht12rs7%2FE
-
Raemdonck K, Vandenbroucke RE, Demeester J, Sanders NN, De Smedt SC. Maintaining the silence: reflections on long-term RNAi. Drug Discov Today. 2008;13:917-31.
-
(2008)
Drug Discov Today
, vol.13
, pp. 917-931
-
-
Raemdonck, K.1
Vandenbroucke, R.E.2
Demeester, J.3
Sanders, N.N.4
De Smedt, S.C.5
-
148
-
-
62749166288
-
Oral delivery of DNA construct using chitosan nanoparticles to protect the shrimp from white spot syndrome virus (WSSV)
-
19141321 1:CAS:528:DC%2BD1MXjvVaisb0%3D
-
Rajeshkumar S, Venkatsean C, Sarathi M, Sarathbabu V, Thomas J, Anver Basha K, Sahul Hameed AS. Oral delivery of DNA construct using chitosan nanoparticles to protect the shrimp from white spot syndrome virus (WSSV). Fish Shellfish Immunol. 2009;26:429-37.
-
(2009)
Fish Shellfish Immunol
, vol.26
, pp. 429-437
-
-
Rajeshkumar, S.1
Venkatsean, C.2
Sarathi, M.3
Sarathbabu, V.4
Thomas, J.5
Anver Basha, K.6
Sahul Hameed, A.S.7
-
149
-
-
18044364215
-
Molecular mechanisms of RNAi: Implications for development and disease
-
1:CAS:528:DC%2BD2MXktFSltbw%3D
-
Rao M, Sockanathan S. Molecular mechanisms of RNAi: implications for development and disease. Birth Defects Res C. 2005;75:28-42.
-
(2005)
Birth Defects Res C
, vol.75
, pp. 28-42
-
-
Rao, M.1
Sockanathan, S.2
-
150
-
-
6944232298
-
In vivo comparative study of RNAi methodologies by in ovo electroporation in the chick embryo
-
15376322 1:CAS:528:DC%2BD2cXhtVSgsrjK
-
Rao M, Baraban JH, Rajaii F, Sockanathan S. In vivo comparative study of RNAi methodologies by in ovo electroporation in the chick embryo. Dev Dyn. 2004;231:592-600.
-
(2004)
Dev Dyn
, vol.231
, pp. 592-600
-
-
Rao, M.1
Baraban, J.H.2
Rajaii, F.3
Sockanathan, S.4
-
151
-
-
0042161861
-
Double-stranded RNA-mediated gene silencing in fission yeast
-
Raoni M, Arndt GM. Double-stranded RNA-mediated gene silencing in fission yeast. Nucleic Acids Res. 2003;31:4481-9.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 4481-4489
-
-
Raoni, M.1
Arndt, G.M.2
-
152
-
-
13244255256
-
Heterologous expression of plant virus genes that suppress post-transcriptional gene silencing results in suppression of RNA interference in Drosophila cells
-
15331016
-
Reavy B, Dawson S, Canto T, MacFarlane SA. Heterologous expression of plant virus genes that suppress post-transcriptional gene silencing results in suppression of RNA interference in Drosophila cells. BMC Biotechnol. 2004;4:18.
-
(2004)
BMC Biotechnol
, vol.4
, pp. 18
-
-
Reavy, B.1
Dawson, S.2
Canto, T.3
Macfarlane, S.A.4
-
153
-
-
0037072660
-
Small RNAs correspond to centromere heterochromatic repeats
-
12193644 1:CAS:528:DC%2BD38Xnt1Shsr8%3D
-
Reinhart BJ, Bartel DP. Small RNAs correspond to centromere heterochromatic repeats. Science. 2002;297:1831.
-
(2002)
Science
, vol.297
, pp. 1831
-
-
Reinhart, B.J.1
Bartel, D.P.2
-
154
-
-
27144463588
-
Double-stranded RNA induces sequence-specific antiviral silencing in addition to nonspecific immunity in a marine shrimp: Convergence of RNA interference and innate immunity in the invertebrate antiviral response?
-
16227276 1:CAS:528:DC%2BD2MXhtFKjtr%2FN
-
Robalino J, Bartlett T, Shepard E, Prior S, Jaramillo G, Scura E, Chapman RW, Gross PS, Browdy CL, Warr GW. Double-stranded RNA induces sequence-specific antiviral silencing in addition to nonspecific immunity in a marine shrimp: convergence of RNA interference and innate immunity in the invertebrate antiviral response? J Virol. 2005;79:13561-71.
-
(2005)
J Virol
, vol.79
, pp. 13561-13571
-
-
Robalino, J.1
Bartlett, T.2
Shepard, E.3
Prior, S.4
Jaramillo, G.5
Scura, E.6
Chapman, R.W.7
Gross, P.S.8
Browdy, C.L.9
Warr, G.W.10
-
155
-
-
33846368080
-
Double-stranded RNA and antiviral immunity in marine shrimp: Inducible host mechanisms and evidence for the evolution of viral counter-responses
-
17109960 1:CAS:528:DC%2BD2sXntlCiug%3D%3D
-
Robalino J, Bartlett TC, Chapman RW, Gross PS, Browdy CL, Warr GW. Double-stranded RNA and antiviral immunity in marine shrimp: inducible host mechanisms and evidence for the evolution of viral counter-responses. Dev Comp Immunol. 2007;31:539-47.
-
(2007)
Dev Comp Immunol
, vol.31
, pp. 539-547
-
-
Robalino, J.1
Bartlett, T.C.2
Chapman, R.W.3
Gross, P.S.4
Browdy, C.L.5
Warr, G.W.6
-
156
-
-
0031770243
-
Viral vectors for gene therapy
-
9804053 1:CAS:528:DyaK1cXmtFyisb0%3D
-
Robbins PD, Ghivizzani SC. Viral vectors for gene therapy. Pharmacol Ther. 1998;80:35-47.
-
(1998)
Pharmacol Ther
, vol.80
, pp. 35-47
-
-
Robbins, P.D.1
Ghivizzani, S.C.2
-
157
-
-
0037373298
-
Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila
-
12592004 1:CAS:528:DC%2BD3sXhslWjurk%3D
-
Roignant JY, Carre C, Mugat B, Szymczak D, Lepesant JA, Antoliewski C. Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila. RNA. 2003;9:299-308.
-
(2003)
RNA
, vol.9
, pp. 299-308
-
-
Roignant, J.Y.1
Carre, C.2
Mugat, B.3
Szymczak, D.4
Lepesant, J.A.5
Antoliewski, C.6
-
158
-
-
0029242185
-
AAV as a viral vector for human gene therapy. Generation of recombinant virus
-
7606507 1:CAS:528:DyaK2MXkvVGjsro%3D
-
Rolling F, Samulski RJ. AAV as a viral vector for human gene therapy. Generation of recombinant virus. Mol Biotechnol. 1995;3:9-15.
-
(1995)
Mol Biotechnol
, vol.3
, pp. 9-15
-
-
Rolling, F.1
Samulski, R.J.2
-
159
-
-
34548735210
-
Dynamic polyconjugates for targeted in vivo delivery of siRNA to hepatocytes
-
Rosema DB, Lewis DL, Wakefield DH, Wong SC, Klein JJ, Roesch PL, Bertin SL, Reppin TW, Chu Q, Blokhin AV, Hagstrom JE, Wolff JA. Dynamic polyconjugates for targeted in vivo delivery of siRNA to hepatocytes. Proc Natl Acad Sci USA. 2007;104:12982-7.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12982-12987
-
-
Rosema, D.B.1
Lewis, D.L.2
Wakefield, D.H.3
Wong, S.C.4
Klein, J.J.5
Roesch, P.L.6
Bertin, S.L.7
Reppin, T.W.8
Chu, Q.9
Blokhin, A.V.10
Hagstrom, J.E.11
Wolff, J.A.12
-
160
-
-
11144352102
-
Baculovirus solves a complex problem
-
15583659 1:CAS:528:DC%2BD2cXhtVCku7zP
-
Roy P. Baculovirus solves a complex problem. Nat Biotechnol. 2004;22:1527-8.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1527-1528
-
-
Roy, P.1
-
161
-
-
0029047860
-
DNA synthesis and topoisomerase inhibitors increase transduction by adeno-associated virus vectors
-
7777575 1:CAS:528:DyaK2MXmtFOgtL4%3D
-
Russell DW, Alexander IE, Millar D. DNA synthesis and topoisomerase inhibitors increase transduction by adeno-associated virus vectors. Proc Natl Acad Sci USA. 1995;92:5719-23.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5719-5723
-
-
Russell, D.W.1
Alexander, I.E.2
Millar, D.3
-
162
-
-
0142173075
-
Small RNAs with imperfect match to endogenous mRNA repress translation
-
Saxena S, Jonsson ZO, Dutta A. Small RNAs with imperfect match to endogenous mRNA repress translation. J Biol Chem. 2003;278:44312-44319.
-
(2003)
J Biol Chem.
, vol.278
, pp. 44312-44319
-
-
Saxena, S.1
Jonsson, Z.O.2
Dutta, A.3
-
163
-
-
10744219688
-
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells
-
14769924 1:CAS:528:DC%2BD2cXhs1Sktbw%3D
-
Scacheri PC, Rozenblatt-Rosen O, Caplen NJ, Wolfsberg TG, Umayam L, Lee JC, Hughes CM, Shanmugam KS, Bhattacharjee A, Meyerson M, Collins FS. Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc Natl Acad Sci USA. 2004;101:1892-7.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 1892-1897
-
-
Scacheri, P.C.1
Rozenblatt-Rosen, O.2
Caplen, N.J.3
Wolfsberg, T.G.4
Umayam, L.5
Lee, J.C.6
Hughes, C.M.7
Shanmugam, K.S.8
Bhattacharjee, A.9
Meyerson, M.10
Collins, F.S.11
-
164
-
-
0037294039
-
Non-viral and hybrid vectors in human gene therapy: An update
-
12615040 1:CAS:528:DC%2BD3sXhsVWqsrc%3D
-
Schmidt-Wolf GD, Schmidt-Wolf IGH. Non-viral and hybrid vectors in human gene therapy: an update. Trends Mol Med. 2003;9:67-72.
-
(2003)
Trends Mol Med
, vol.9
, pp. 67-72
-
-
Schmidt-Wolf, G.D.1
Schmidt-Wolf, I.G.H.2
-
165
-
-
0036752955
-
Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways
-
12408822 1:CAS:528:DC%2BD38XnvFSlt7g%3D
-
Schwarz DS, Hutvagner G, Haley B, Zamore PD. Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Mol Cell. 2002;10:537-48.
-
(2002)
Mol Cell
, vol.10
, pp. 537-548
-
-
Schwarz, D.S.1
Hutvagner, G.2
Haley, B.3
Zamore, P.D.4
-
166
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
14567917 1:CAS:528:DC%2BD3sXosFCqsLo%3D
-
Schwarz DS, Hutvagner G, Du T, Xu Z, Aronin N, Zamore PD. Asymmetry in the assembly of the RNAi enzyme complex. Cell. 2003;115:199-208.
-
(2003)
Cell
, vol.115
, pp. 199-208
-
-
Schwarz, D.S.1
Hutvagner, G.2
Du, T.3
Xu, Z.4
Aronin, N.5
Zamore, P.D.6
-
167
-
-
14844303966
-
The prospect of silencing disease using RNA interference
-
Shanker P, Manjunath N, Lieberman J. The prospect of silencing disease using RNA interference. J Am Med Assoc. 2005;293:1367-73.
-
(2005)
J Am Med Assoc
, vol.293
, pp. 1367-1373
-
-
Shanker, P.1
Manjunath, N.2
Lieberman, J.3
-
168
-
-
0035900651
-
On the role of RNA amplification in dsRNA-triggered gene silencing
-
11719187 1:CAS:528:DC%2BD3MXovVCns7k%3D
-
Sijen T, Fleenor J, Simmer F, Thijssen KL, Parrish S, Timmons L, Plasterk RHA, Fire A. On the role of RNA amplification in dsRNA-triggered gene silencing. Cell. 2001;107:465-76.
-
(2001)
Cell
, vol.107
, pp. 465-476
-
-
Sijen, T.1
Fleenor, J.2
Simmer, F.3
Thijssen, K.L.4
Parrish, S.5
Timmons, L.6
Plasterk, R.H.A.7
Fire, A.8
-
169
-
-
0037124354
-
A viral protein suppresses RNA silencing and binds silencing-generated, 21-25-nucleotide double-standed RNAs
-
12065420 1:CAS:528:DC%2BD38XlsVSltbk%3D
-
Silhavy D, Molnar A, Lucioli A, Szittya G, Hornyik C, Tavazza M, Burgyan J. A viral protein suppresses RNA silencing and binds silencing-generated, 21-25-nucleotide double-standed RNAs. EMBO J. 2002;21:3070-80.
-
(2002)
EMBO J
, vol.21
, pp. 3070-3080
-
-
Silhavy, D.1
Molnar, A.2
Lucioli, A.3
Szittya, G.4
Hornyik, C.5
Tavazza, M.6
Burgyan, J.7
-
170
-
-
42149187167
-
RNA interference and its therapeutic potential against HIV infection
-
18352849 1:CAS:528:DC%2BD1cXjsFWktbg%3D
-
Singh SK. RNA interference and its therapeutic potential against HIV infection. Expert Opin Biol Ther. 2008;8:449-61.
-
(2008)
Expert Opin Biol Ther
, vol.8
, pp. 449-461
-
-
Singh, S.K.1
-
171
-
-
0021010433
-
Production of human beta interferon in insect cells with a baculovirus expression vector
-
6318086 1:CAS:528:DyaL2cXhvVOntw%3D%3D
-
Smith GE, Summers MD, Fraser MJ. Production of human beta interferon in insect cells with a baculovirus expression vector. Mol Cell Biol. 1983;3:2156-65.
-
(1983)
Mol Cell Biol
, vol.3
, pp. 2156-2165
-
-
Smith, G.E.1
Summers, M.D.2
Fraser, M.J.3
-
172
-
-
0033122032
-
Adeno-associated virus-mediated gene delivery
-
Snyder RO. Adeno-associated virus-mediated gene delivery. J Gene Med. 1999;1:166.
-
(1999)
J Gene Med.
, vol.1
, pp. 166
-
-
Snyder, R.O.1
-
173
-
-
0037391391
-
A simple and cost-effective method for producing small interfering RNAs with high efficacy
-
Sohail M, Doran G, Riedemann J, Macaulay V, Southern EM. A simple and cost-effective method for producing small interfering RNAs with high efficacy. Nucleic Acids Res. 2003;30:e46.
-
(2003)
Nucleic Acids Res
, vol.30
, pp. 46
-
-
Sohail, M.1
Doran, G.2
Riedemann, J.3
Macaulay, V.4
Southern, E.M.5
-
174
-
-
23844474160
-
Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
-
15908939 1:CAS:528:DC%2BD2MXkvVShs70%3D
-
Song E, Zhu P, Lee SK, Chowdhury D, Kussman S, Dykxhoorn DM, Feng Y, Palliser D, Weiner DB, Shanker P, Marasco WA, Lieberman J. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nat Biotechnol. 2005;23:709-17.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 709-717
-
-
Song, E.1
Zhu, P.2
Lee, S.K.3
Chowdhury, D.4
Kussman, S.5
Dykxhoorn, D.M.6
Feng, Y.7
Palliser, D.8
Weiner, D.B.9
Shanker, P.10
Marasco, W.A.11
Lieberman, J.12
-
175
-
-
26944475149
-
Active RNA silencing at low temperature indicates distinct pathways for antisense-mediated gene-silencing in potato
-
16244909 1:CAS:528:DC%2BD2MXhtFersL%2FK
-
Sos-Hegedus A, Lovas A, Kondrak M, Kovacs G, Banfalvi Z. Active RNA silencing at low temperature indicates distinct pathways for antisense-mediated gene-silencing in potato. Plant Mol Biol. 2005;59:595-602.
-
(2005)
Plant Mol Biol
, vol.59
, pp. 595-602
-
-
Sos-Hegedus, A.1
Lovas, A.2
Kondrak, M.3
Kovacs, G.4
Banfalvi, Z.5
-
176
-
-
38349035712
-
A key gene of the RNA interference pathway in the black tiger shrimp, Penaeus monodon: Identification and functional characterisation of Dicer-1
-
Su J, Oanh DTH, Lyons RE, Leeton L, van Hulten MCW, Tan SH, Song L, Rajendran KV, Walker PJ. A key gene of the RNA interference pathway in the black tiger shrimp, Penaeus monodon: identification and functional characterisation of Dicer-1. Fish Shell Immunol. 2008;24:223-33.
-
(2008)
Fish Shell Immunol
, vol.24
, pp. 223-233
-
-
Su, J.1
Oanh, D.T.H.2
Lyons, R.E.3
Leeton, L.4
Van Hulten, M.C.W.5
Tan, S.H.6
Song, L.7
Rajendran, K.V.8
Walker, P.J.9
-
177
-
-
0037117550
-
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
-
11960009 1:CAS:528:DC%2BD38XjtFKltrg%3D
-
Sui G, Soohoo C, Affar EB, Gay F, Shi Y, Forrester WC, Shi Y. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA. 2002;99:5515-20.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 5515-5520
-
-
Sui, G.1
Soohoo, C.2
Affar, E.B.3
Gay, F.4
Shi, Y.5
Forrester, W.C.6
Shi, Y.7
-
178
-
-
0038805301
-
Immune responses to adeno-associated virus and its recombinant vectors
-
12756417 1:CAS:528:DC%2BD3sXjvVagt70%3D
-
Sun JY, Anand-Jawa V, Chatterjee S, Wong KK. Immune responses to adeno-associated virus and its recombinant vectors. Gene Ther. 2003;10:964-76.
-
(2003)
Gene Ther
, vol.10
, pp. 964-976
-
-
Sun, J.Y.1
Anand-Jawa, V.2
Chatterjee, S.3
Wong, K.K.4
-
179
-
-
0032717319
-
The rde-1 gene, RNA interference and transposon silencing in C. elegans
-
Tabara H, Sarkissian M, Kelly WG, Fleenor J, Grishok A, Timmons L, Fire A, Mello CC. The rde-1 gene, RNA interference and transposon silencing in C. elegans. Cell 1999;99.
-
(1999)
Cell
, pp. 99
-
-
Tabara, H.1
Sarkissian, M.2
Kelly, W.G.3
Fleenor, J.4
Grishok, A.5
Timmons, L.6
Fire, A.7
Mello, C.C.8
-
180
-
-
0037188904
-
The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-Box helicase to direct RNAi in C. elegans
-
Tabara H, Yigit E, Siomi H, Mello CC. The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-Box helicase to direct RNAi in C. elegans. Cell. 2003;109:861-71.
-
(2003)
Cell
, vol.109
, pp. 861-871
-
-
Tabara, H.1
Yigit, E.2
Siomi, H.3
Mello, C.C.4
-
181
-
-
2442668068
-
A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics
-
15150085 1:CAS:528:DC%2BD2cXktVWhsrc%3D
-
Takei Y, Kadmoatsu K, Yuzawa Y, Matsuo S, Muramatsu T. A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics. Cancer Res. 2004;64:3365-70.
-
(2004)
Cancer Res
, vol.64
, pp. 3365-3370
-
-
Takei, Y.1
Kadmoatsu, K.2
Yuzawa, Y.3
Matsuo, S.4
Muramatsu, T.5
-
182
-
-
1842478940
-
RNA interference as a new biotechnological tool for the control of virus diseases in plants
-
Tenllado F, Llave C, Diaz-Ruiz JR. RNA interference as a new biotechnological tool for the control of virus diseases in plants. Virus Res. 2001;102:85-96.
-
(2001)
Virus Res
, vol.102
, pp. 85-96
-
-
Tenllado, F.1
Llave, C.2
Diaz-Ruiz, J.R.3
-
183
-
-
0038574350
-
Non-viral gene therapy: Polycation-mediated DNA delivery
-
12719940 1:CAS:528:DC%2BD3sXltVWgsrg%3D
-
Thomas M, Klibanov AM. Non-viral gene therapy: polycation-mediated DNA delivery. Appl Microbiol Biotechnol. 2003;62:27-34.
-
(2003)
Appl Microbiol Biotechnol
, vol.62
, pp. 27-34
-
-
Thomas, M.1
Klibanov, A.M.2
-
184
-
-
0035941485
-
Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans
-
11223248 1:CAS:528:DC%2BD3MXht1Oku70%3D
-
Timmons L, Court DL, Fire A. Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene. 2001;263:103-12.
-
(2001)
Gene
, vol.263
, pp. 103-112
-
-
Timmons, L.1
Court, D.L.2
Fire, A.3
-
185
-
-
3142518230
-
Using RNA interference to develop dengue virus resistance in genetically modified Aedes aegypti
-
15242701 1:CAS:528:DC%2BD2cXls1WmtLg%3D
-
Travanty EA, Adelman ZN, Franz AW, Keene KM, Beaty BJ, Blair CD, James AA, Olson KE. Using RNA interference to develop dengue virus resistance in genetically modified Aedes aegypti. Insect Biochem Mol Biol. 2004;34:607-13.
-
(2004)
Insect Biochem Mol Biol
, vol.34
, pp. 607-613
-
-
Travanty, E.A.1
Adelman, Z.N.2
Franz, A.W.3
Keene, K.M.4
Beaty, B.J.5
Blair, C.D.6
James, A.A.7
Olson, K.E.8
-
186
-
-
44349134976
-
Muscle cell migrations of C. elegans are mediated by the alpha-integrin INA-1, Eph receptor VAB-1, and a novel peptidase homologue MNP-1
-
18452914 1:CAS:528:DC%2BD1cXmsFKrtrs%3D
-
Tucker M, Han M. Muscle cell migrations of C. elegans are mediated by the alpha-integrin INA-1, Eph receptor VAB-1, and a novel peptidase homologue MNP-1. Dev Biol. 2008;318:215-23.
-
(2008)
Dev Biol
, vol.318
, pp. 215-223
-
-
Tucker, M.1
Han, M.2
-
187
-
-
0035999373
-
Spreading of RNA targeting and DNA methylation in RNA silencing requires transcription of the target gene and a putative RNA-dependent RNA polymerase
-
11971140 1:CAS:528:DC%2BD38XjsFWktr8%3D
-
Vaistij FE, Jones L, Baulcombe D. Spreading of RNA targeting and DNA methylation in RNA silencing requires transcription of the target gene and a putative RNA-dependent RNA polymerase. Plant Cell. 2002;14:857-67.
-
(2002)
Plant Cell
, vol.14
, pp. 857-867
-
-
Vaistij, F.E.1
Jones, L.2
Baulcombe, D.3
-
188
-
-
0025405838
-
Flavonoid genes in petunia: Addition of a limited number of gene copies may lead to a suppression of gene expression
-
2152117
-
Van der Krol AR, Mur LA, Beld M, Mol JNM, Stuitje AR. Flavonoid genes in petunia: addition of a limited number of gene copies may lead to a suppression of gene expression. Plant Cell. 1990;2:291-9.
-
(1990)
Plant Cell
, vol.2
, pp. 291-299
-
-
Van Der Krol, A.R.1
Mur, L.A.2
Beld, M.3
Mol, J.N.M.4
Stuitje, A.R.5
-
189
-
-
0037253319
-
RNA target sequences promote spreading of RNA silencing
-
12529532
-
Van Houdt H, Bleys A, Depicker A. RNA target sequences promote spreading of RNA silencing. Plant Physiol. 2003;131:245-53.
-
(2003)
Plant Physiol
, vol.131
, pp. 245-253
-
-
Van Houdt, H.1
Bleys, A.2
Depicker, A.3
-
190
-
-
0042924332
-
Short interfering RNA-mediated interference of gene expression and viral DNA accumulation in cultured plant cells
-
12886005 1:CAS:528:DC%2BD3sXmtlyrs74%3D
-
Vanitharani R, Chellappan P, Fauquet CM. Short interfering RNA-mediated interference of gene expression and viral DNA accumulation in cultured plant cells. Proc Natl Acad Sci USA. 2003;100:9632-6.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9632-9636
-
-
Vanitharani, R.1
Chellappan, P.2
Fauquet, C.M.3
-
191
-
-
0034320366
-
A tumultuous year for gene therapy
-
11082313 1:CAS:528:DC%2BD38XhvFKisb4%3D
-
Verma M. A tumultuous year for gene therapy. Mol Ther. 2000;2:415-6.
-
(2000)
Mol Ther
, vol.2
, pp. 415-416
-
-
Verma, M.1
-
192
-
-
0030928619
-
Gene therapy- promises, problems and prospects
-
9305836 1:CAS:528:DyaK2sXmtFGjt74%3D
-
Verma IM, Somia N. Gene therapy- promises, problems and prospects. Nature. 1997;389:239-42.
-
(1997)
Nature
, vol.389
, pp. 239-242
-
-
Verma, I.M.1
Somia, N.2
-
193
-
-
0033598840
-
Suppression of gene silencing: A general strategy used by diverse DNA and RNA viruses of plants
-
10570213 1:CAS:528:DyaK1MXns1yjs7o%3D
-
Voinnet O, Pinto YM, Baulcombe D. Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants. Proc Natl Acad Sci USA. 1999;96:14147-52.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14147-14152
-
-
Voinnet, O.1
Pinto, Y.M.2
Baulcombe, D.3
-
194
-
-
0030161017
-
Second-generation adenovirus vectors
-
8640568 1:CAS:528:DyaK28XjsVSjurY%3D
-
Wang Q, Finer MH. Second-generation adenovirus vectors. Nat Med. 1996;2:714-6.
-
(1996)
Nat Med
, vol.2
, pp. 714-716
-
-
Wang, Q.1
Finer, M.H.2
-
195
-
-
41649105281
-
Inhibiting colorectal carcinoma growth and metastasis by blocking the expression of VEGF using RNA interference
-
18392139 1:CAS:528:DC%2BD1cXltleiu7o%3D
-
Wang S, Liu H, Ren L, Pan Y, Zhang Y. Inhibiting colorectal carcinoma growth and metastasis by blocking the expression of VEGF using RNA interference. Neoplasia. 2008;10:399-407.
-
(2008)
Neoplasia
, vol.10
, pp. 399-407
-
-
Wang, S.1
Liu, H.2
Ren, L.3
Pan, Y.4
Zhang, Y.5
-
196
-
-
0032506226
-
Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA
-
9811908 1:CAS:528:DyaK1cXnsVGhurk%3D
-
Waterhouse PM, Graham MW, Wang MB. Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA. Proc Natl Acad Sci USA. 1998;95:13959-64.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13959-13964
-
-
Waterhouse, P.M.1
Graham, M.W.2
Wang, M.B.3
-
197
-
-
27744573296
-
SiRNA injection induces sequence-independent protection in Penaeus monodon against white spot syndrome virus
-
16043253 1:CAS:528:DC%2BD2MXht1WjtLbN
-
Westenberg M, Heinhuis B, Zuidema D, Vlak JM. siRNA injection induces sequence-independent protection in Penaeus monodon against white spot syndrome virus. Virus Res. 2005;114:133-9.
-
(2005)
Virus Res
, vol.114
, pp. 133-139
-
-
Westenberg, M.1
Heinhuis, B.2
Zuidema, D.3
Vlak, J.M.4
-
198
-
-
0033789992
-
Specific interference with gene function by double-stranded RNA in early mouse development
-
10655585 1:CAS:528:DC%2BD3cXhtVyltL8%3D
-
Wianny F, Zernicka-Goetz M. Specific interference with gene function by double-stranded RNA in early mouse development. Nat Cell Biol. 2000;2:70-5.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 70-75
-
-
Wianny, F.1
Zernicka-Goetz, M.2
-
199
-
-
0029586317
-
Targeting of adenovirus penton base to new receptors through replacement of its RGD motif with other receptor-specific peptide motifs
-
8750015 1:CAS:528:DyaK2MXhtVSktrrM
-
Wickham TJ, Carrion ME, Kovesdi I. Targeting of adenovirus penton base to new receptors through replacement of its RGD motif with other receptor-specific peptide motifs. Gene Ther. 1995;2:750-6.
-
(1995)
Gene Ther
, vol.2
, pp. 750-756
-
-
Wickham, T.J.1
Carrion, M.E.2
Kovesdi, I.3
-
200
-
-
0029794681
-
Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies
-
8794324 1:CAS:528:DyaK28XlslSqu78%3D
-
Wickham TJ, Segal DM, Roelvink PW, Carrion ME, Lizonova A, Lee GM, Kovesdi I. Targeted adenovirus gene transfer to endothelial and smooth muscle cells by using bispecific antibodies. J Virol. 1996;70:6831-8.
-
(1996)
J Virol
, vol.70
, pp. 6831-6838
-
-
Wickham, T.J.1
Segal, D.M.2
Roelvink, P.W.3
Carrion, M.E.4
Lizonova, A.5
Lee, G.M.6
Kovesdi, I.7
-
201
-
-
0037076320
-
ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos
-
12011447 1:CAS:528:DC%2BD38XjvFCru7k%3D
-
Williams RW, Rubin GM. ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos. Proc Natl Acad Sci USA. 2002;99:6889-94.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6889-6894
-
-
Williams, R.W.1
Rubin, G.M.2
-
202
-
-
0034634360
-
Transgene and transposon silencing in Chlamydomonas reinhardtii by a DEAH-box RNA helicase
-
11073454 1:CAS:528:DC%2BD3cXotVChsbg%3D
-
Wu-Scharf D, Jeong B, Chang C, Cerutti H. Transgene and transposon silencing in Chlamydomonas reinhardtii by a DEAH-box RNA helicase. Science. 2000;290:1159-62.
-
(2000)
Science
, vol.290
, pp. 1159-1162
-
-
Wu-Scharf, D.1
Jeong, B.2
Chang, C.3
Cerutti, H.4
-
203
-
-
0029028989
-
Clearance of adenovirus-infected hepatocytes by MHC class I-restricted CD4+CTLs in vivo
-
7650386 1:CAS:528:DyaK2MXnsFygu7Y%3D
-
Yang Y, Wilson JM. Clearance of adenovirus-infected hepatocytes by MHC class I-restricted CD4+CTLs in vivo. J Immunol. 1995;155:2564-70.
-
(1995)
J Immunol
, vol.155
, pp. 2564-2570
-
-
Yang, Y.1
Wilson, J.M.2
-
204
-
-
0029836503
-
Role of viral antigens in destructive cellular immune responses to adenovirus vector-transduced cells in mouse lungs
-
8794368 1:CAS:528:DyaK28XlslWjsbs%3D
-
Yang Y, Su Q, Wilson JM. Role of viral antigens in destructive cellular immune responses to adenovirus vector-transduced cells in mouse lungs. J Virol. 1996;70:7209-12.
-
(1996)
J Virol
, vol.70
, pp. 7209-7212
-
-
Yang, Y.1
Su, Q.2
Wilson, J.M.3
-
205
-
-
0034609759
-
Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos
-
11050387 1:CAS:528:DC%2BD3cXotVSrtLo%3D
-
Yang D, Lu H, Erickson JW. Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos. Curr Biol. 2000;10:1191-200.
-
(2000)
Curr Biol
, vol.10
, pp. 1191-1200
-
-
Yang, D.1
Lu, H.2
Erickson, J.W.3
-
206
-
-
0037162522
-
Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
-
12096193 1:CAS:528:DC%2BD38XlslKgtr4%3D
-
Yang D, Buchholz F, Huang Z, Goga A, Chen CY, Brodsky FM, Bishop JM. Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells. Proc Natl Acad Sci USA. 2002;99:9942-7.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 9942-9947
-
-
Yang, D.1
Buchholz, F.2
Huang, Z.3
Goga, A.4
Chen, C.Y.5
Brodsky, F.M.6
Bishop, J.M.7
-
207
-
-
31444450486
-
YHV-protease dsRNA inhibits YHV replication in Penaeus monodon and prevents mortality
-
16426575 1:CAS:528:DC%2BD28XhtFaks78%3D
-
Yodmuang S, Tirasophon W, Roshorm Y, Chinnirunvong W, Panyim S. YHV-protease dsRNA inhibits YHV replication in Penaeus monodon and prevents mortality. Biochem Biophys Res Commun. 2006;341:351-6.
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 351-356
-
-
Yodmuang, S.1
Tirasophon, W.2
Roshorm, Y.3
Chinnirunvong, W.4
Panyim, S.5
-
208
-
-
0031575841
-
VSV-G-pseudotyped retroviral packaging through adenovirus-mediated inducible gene expression
-
9125185 1:CAS:528:DyaK2sXhvF2jsrc%3D
-
Yoshida Y, Emi N, Hamada H. VSV-G-pseudotyped retroviral packaging through adenovirus-mediated inducible gene expression. Biochem Biophys Res Commun. 1997;232:379-82.
-
(1997)
Biochem Biophys Res Commun
, vol.232
, pp. 379-382
-
-
Yoshida, Y.1
Emi, N.2
Hamada, H.3
-
209
-
-
33645537549
-
RNAi is an antiviral immune response against a dsRNA virus in Drosophila melanogaster
-
16611236 1:CAS:528:DC%2BD28XkvVWnsrw%3D
-
Zambon RA, Vakharia VN, Wu LP. RNAi is an antiviral immune response against a dsRNA virus in Drosophila melanogaster. Cell Microbiol. 2006;8:880-9.
-
(2006)
Cell Microbiol
, vol.8
, pp. 880-889
-
-
Zambon, R.A.1
Vakharia, V.N.2
Wu, L.P.3
-
210
-
-
0034737298
-
RNAi: Double-Stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
-
10778853 1:CAS:528:DC%2BD3cXisVaitbo%3D
-
Zamore PD, Tuschi T, Sharp PA, Bartel DP. RNAi: double-Stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell. 2000;101:25-33.
-
(2000)
Cell
, vol.101
, pp. 25-33
-
-
Zamore, P.D.1
Tuschi, T.2
Sharp, P.A.3
Bartel, D.P.4
-
211
-
-
33644822016
-
Transiently expressed short hairpin RNA targeting 126 kDa protein of tobacco mosaic virus interferes with virus infection
-
Zao MM, An DR, Zhao J, Huang GH, He ZH, Chen JY. Transiently expressed short hairpin RNA targeting 126 kDa protein of tobacco mosaic virus interferes with virus infection. Acta Biochim Biophys Sin. 2006;38:22-8.
-
(2006)
Acta Biochim Biophys Sin
, vol.38
, pp. 22-28
-
-
Zao, M.M.1
An, D.R.2
Zhao, J.3
Huang, G.H.4
He, Z.H.5
Chen, J.Y.6
-
212
-
-
0036074161
-
RNA interference in human cells is restricted to the cytoplasm
-
12166640 1:CAS:528:DC%2BD38Xls1Ohs7w%3D
-
Zeng Y, Cullen BR. RNA interference in human cells is restricted to the cytoplasm. RNA. 2002;8:855-60.
-
(2002)
RNA
, vol.8
, pp. 855-860
-
-
Zeng, Y.1
Cullen, B.R.2
-
213
-
-
44349193870
-
Functional specialization among insect chitinase family genes revealed by RNA interference
-
18436642 1:CAS:528:DC%2BD1cXmtVOmu7w%3D
-
Zhu Q, Arakane Y, Beeman RW, Kramer KJ, Muthukrishnan S. Functional specialization among insect chitinase family genes revealed by RNA interference. Proc Natl Acad Sci USA. 2008;105:6650-65.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 6650-6665
-
-
Zhu, Q.1
Arakane, Y.2
Beeman, R.W.3
Kramer, K.J.4
Muthukrishnan, S.5
|