Silence of the strands: RNA interference in eukaryotic pathogens

Trends in Microbiology

Volumn 11, Issue 1, 2003, Pages 37-43

  Cottrell, Tricia R ^a   Doering, Tamara L ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DOUBLE STRANDED RNA; MESSENGER RNA; RNA;

ASPERGILLUS FUMIGATUS; CAENORHABDITIS ELEGANS; CANDIDA ALBICANS; CRYPTOCOCCUS NEOFORMANS; DROSOPHILA; EUKARYOTE; FUNGUS; GENE EXPRESSION; GENE SEQUENCE; GENE SILENCING; GENETIC MANIPULATION; GENOME ANALYSIS; HISTOPLASMA CAPSULATUM; HUMAN; LEISHMANIA MAJOR; NEUROSPORA; NONHUMAN; PLANT; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTOZOON; REVIEW; RNA DEGRADATION; RNA SEQUENCE; TECHNIQUE; TOXOPLASMA GONDII; TRYPANOSOMA BRUCEI;

ANIMALS; EUKARYOTIC CELLS; FUNGI; HUMANS; MODELS, GENETIC; PROTOZOA; RNA INTERFERENCE; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, DOUBLE-STRANDED; RNA, FUNGAL; RNA, PROTOZOAN;

AJELLOMYCES; AJELLOMYCES CAPSULATUS; ASPERGILLUS; ASPERGILLUS FUMIGATUS; CAENORHABDITIS; CAENORHABDITIS ELEGANS; CANDIDA; CANDIDA ALBICANS; EUKARYOTA; FILOBASIDIELLA NEOFORMANS; FUNGI; LEISHMANIA MAJOR; NEUROSPORA; PLASMODIUM FALCIPARUM; PROTOZOA; TOXOPLASMA GONDII; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

EID: 0037232973     PISSN: 0966842X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0966-842X(02)00004-5     Document Type: Review

References (49)

1. Bernstein E., et al. The rest is silence. RNA. 7:2001;1509-1521.
2. Zamore P.D. Ancient pathways programmed by small RNAs. Science. 296:2002;1265-1269.
3. Hutvagner G., Zamore P.D. A microRNA in a multiple-turnover RNAi enzyme complex. Science. 297:2002;2056-2060.
4. Plasterk R.H.A. RNA silencing: the genome's immune system. Science. 296:2002;1263-1265.
5. Nishikura K. A short primer on RNAi: RNA-directed RNA polymerase acts as a key catalyst. Cell. 107:2001;415-418.
6. Zamore P.D. RNA interference: listening to the sound of silence. Nat. Struc. Biol. 8:2001;746-750.
7. Djikeng A., et al. RNA interference in Trypanosoma brucei: cloning of small interfering RNAs provides evidence for retrotransposon-derived 24-26-nucleotide RNAs. RNA. 7:2001;1522-1530.
8. Moss E.G. RNA interference: It's a small RNA world. Curr. Biol. 11:2001;R772-R775.
9. Hannon G.J. RNA interference. Nature. 418:2002;244-251.
10. Volpe T., et al. Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science. 2002;. DOI: 10.1126/science.1074973.
11. Zoraghi R., Seebeck T. The cAMP-specific phosphodiesterase TbPDE2C is an essential enzyme in bloodstream form Trypanosoma brucei. Proc. Natl Acad. Sci. USA. 99:2002;4343-4348.
12. Schmid A., et al. Combinatorial RNAi: a method for evaluating the functions of gene families in Drosophila. Trends Neurosci. 25:2002;71-74.
13. Celotto A.M., Graveley B.R. Exon-specific RNAi: a tool for dissecting the functional relevance of alternative splicing. RNA. 8:2002;718-724.
14. Fraser A.G., et al. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature. 408:2000;325-330.
15. Ullu E., et al. RNA interference: advances and questions. Phil. Trans. R. Soc. Lond. B. 357:2002;65-70.
16. Morris J.C., et al. Inhibition of bloodstream form Trypanosoma brucei gene expression by RNA interference using the pZJM dual TT7 vector. Mol. Biochem. Parasitol. 117:2001;111-113.
17. Ngo H., et al. Double stranded RNA induces mRNA degradation in Trypanosoma brucei. Proc. Natl Acad. Sci. USA. 95:1998;15502-15507.
18. Wirtz E., et al. Regulated processive transcription of chromatin by T7 RNA polymerase in Trypanosoma brucei. Nucleic Acids Res. 26:1998;4626-4634.
19. Wang Z., et al. Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promoters. J. Biol. Chem. 275:2000;40174-40179.
20. LaCount D.J., et al. Double-stranded RNA interference in Trypanosoma brucei using head-to-head promoters. Mol. Biochem. Parasitol. 111:2000;67-76.
21. Ullu E., Tschudi C. RNAi - applications in parasitology. Parasitol. Today. 2000:2000;43-46.
22. Bastin P., et al. Flagellum ontogeny in trypanosomes studied via an inherited and regulated RNA interference system. J. Cell Sci. 113:2000;3321-3328.
23. Grams J., et al. A trypanosome mitochondrial RNA polymerase is required for transcription and replication. J. Biol. Chem. 277:2002;16952-16959.
24. Guerra-Giraldez C., et al. Compartmentation of enzymes in a microbody, the glycosome, is essential in Trypanosoma brucei. J. Cell Sci. 115:2002;2651-2658.
25. Wang Z., Englund P.T. RNA interference of a trypanosome topoisomerase II causes progressive loss of mitochondrial DNA. EMBO J. 20:2001;4674-4682.
26. LaCount D.J., et al. Trypanosoma brucei FLA1 is required for flagellum attachment and cytokinesis. J. Biol. Chem. 277:2002;17580-17588.
27. Morris J.C., et al. Glycolysis modulates trypanosome glycoprotein expression as revealed by an RNAi library. EMBO J. 21:2002;4429-4438.
28. Kumar R., et al. Characterization and expression of a PPI serine/threonine protein phosphatase (PfPPI) from the malaria parasite, Plasmodium falciparum: demonstration of its essential role using RNA interference. Malaria J. 1:2002;5-16.
29. McRobert L., McConkey G.A. RNA interference (RNAi) inhibits growth of Plasmodium falciparum. Mol. Biochem. Parasitol. 119:2002;273-278.
30. Malhotra P., et al. Double-stranded RNA-mediated gene silencing of cysteine proteases (falcipain-1 and -2) of Plasmodium falciparum. Mol. Microbiol. 45:2002;1245-1254.
31. Cogoni C. Homology-dependent gene silencing mechanisms in fungi. Annu. Rev. Microbiol. 55:2001;381-406.
32. Tentler S., et al. Inhibition of Neurospora crassa growth by a glucan synthase-1 antisense construct. Curr. Microbiol. 34:1997;303-308.
33. Gorlach J.M., et al. Antisense repression in Cryptococcus neoformans as a laboratory tool and potential antifungal strategy. Microbiology. 148:2002;213-219.
34. De Backer M.D., et al. An antisense-based functional genomics approach for indentification of genes critical for growth of Candida albicans. Nat. Biotechnol. 19:2001;235-241.
35. Liu H., et al. RNA interference in the pathogenic fungus Cryptococcus neoformans. Genetics. 160:2002;463-470.
36. Donzé O., Picard D. RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res. 30:(10):2002;e46.
37. Kuwabara E., Coulson A. RNAi - prospects for a general technique for determining gene function. Parasitol. Today. 16:2000;347-349.
38. Elbashir S., et al. Duplexes of 21-nucleotide RNAs mediate interference in cultured mammalian cells. Nature. 411:2001;494-498.
39. Drozdz M., et al. RNA interference in trypanosomes transfected with sense and antisense plasmids. Mol. Biochem. Parasitol. 121:2002;149-152.
40. Williams B.R. PKR; a sentinel kinase for cellular stress. Oncogene. 18:1999;6112-6120.
41. Elbashir S.M., et al. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods. 26:2002;199-213.
42. Sijen T., et al. On the role of RNA amplification in dsRNA-triggered gene silencing. Cell. 107:2001;465-476.
43. Brummelkamp T.R., et al. A system for stable expression of short interfering RNAs in mammalian cells. Science. 296:2002;550-553.
44. McManus M.T., et al. Gene silencing using micro-RNA designed hairpins. RNA. 8:2002;842-850.
45. Carmichael G.G. Silencing viruses with RNA. Nature. 418:2002;379-380.
46. Novina C.D., et al. siRNA-directed inhibition of HIV-1 infection. Nat. Med. 8:2002;681-686.
47. Jacque J.M., et al. Modulation of HIV-1 replication by RNA interference. Nature. 418:2002;379-380.
48. Gitlin L., et al. Short interfering RNA confers intracellular antiviral immunity in human cells. Nature. 418:2002;430-434.
49. Ahlquist P. RNA-dependent RNA polymerases, viruses, and RNA silencing. Science. 296:2002;1270-1273.