Non-viral and hybrid vectors in human gene therapy: An update

Trends in Molecular Medicine

Volumn 9, Issue 2, 2003, Pages 67-72

  Schmidt Wolf, Gabriele D ^a   Schmidt Wolf, Ingo G H ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG CARRIER; HLA B7 ANTIGEN; LIPID; LIPOSOME; NAKED DNA; NANOPARTICLE; PEPTIDE; PLASMID DNA; POLYAMIDOAMINE; POLYETHYLENEIMINE; POLYLYSINE; POLYMETHACRYLIC ACID; UNCLASSIFIED DRUG;

CLINICAL TRIAL; COST; DNA TRANSFER; DNA VECTOR; ELECTROPORATION; GENE GUN; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; INJECTION; JET INJECTION; NONVIRAL GENE DELIVERY SYSTEM; PLASMID; REVIEW; SAFETY; ULTRASOUND; VIRUS CAPSID;

MIRIDAE;

EID: 0037294039     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4914(03)00005-4     Document Type: Review

References (50)

1. Verma, I.M. (2000) A tumultous year for gene therapy. Mol. Ther. 2, 415-416
2. Lollo, C.P. et al. (2000) Obstacles and advances in non-viral gene delivery. Curr. Opin. Mol. Ther. 2, 136-142
3. Felgner, P.L. et al. (1997) Nomenclature for synthetic gene delivery systems. Hum. Gene Ther. 8, 511-512
4. Zauner, W. et al. (1998) Polylysine-based transfection systems utilizing receptor-mediated delivery. Adv. Drug Deliv. Rev. 30, 97-113
5. Ledley, F.D. (1995) Nonviral gene therapy: the promise of genes as pharmaceutical products. Hum. Gene Ther. 6, 1129-1144
6. Huang, C.H. et al. (1999) Nonviral Vectors for Gene Therapy, Academic Press
7. Rolland, A.P. (1998) From genes to gene medicines: recent advances in nonviral gene delivery. Crit. Rev. Ther. Drug Carrier Syst. 15, 143-198
8. Audouy, S.A. et al. (2002) In vivo characteristics of cationic liposomes as delivery vectors for gene therapy. Pharm. Res. 19, 1599-1605
9. Vogel, J.C. (2000) Nonviral skin therapy. Hum. Gene Ther. 11, 2253-2259
10. Horn, N. et al. (1995) Cancer gene therapy using plasmid DNA: purification of DNA for human clinical trials. Hum. Gene Ther. 6, 565-573
11. Hartikka, J. et al. (1996) An improved plasmid DNA expression vector for direct injection into skeletal muscle. Hum. Gene Ther. 7, 1205-1217
12. Lui, V.W.Y. et al. (2001) Systemic production of IL-12 by naked DNA mediated gene transfer: toxicity and attenuation of transgene expression in vivo. J. Gene Med. 3, 384-393
13. Schultz, J. et al. (1999) Long-lasting anti-metastatic efficiency of interleukin-12-encoding plasmid DNA. Hum. Gene Ther. 10, 407-417
14. Blezinger, P. et al. (1999) Systemic inhibition of tumor growth and tumor metastases by intramuscular administration of the endostatin gene. Nat. Biotechnol. 17, 343-348
15. Canatella, P.J. and Prausnitz, M.R. (2001) Prediction and optimization of gene transfection and drug delivery by electroporation. Gene Ther. 8, 1464-1469
16. Buttgereit, P. and Schmidt-Wolf, I.G.H. (2002) Gene therapy of lymphoma. J. Hematother. Stem Cell Res. 11, 457-467
17. Somiari, S. et al. (2000) Theory and in vivo application of electroporative gene delivery. Mol. Ther. 2, 178-187
18. Satkauskas, S. et al. (2002) Mechanisms of in vivo DNA electrotransfer: respective contributions of cell electropermeabilization and DNA electrophoresis. Mol. Ther. 5, 133-140
19. Vilquin, J.T. et al. (2001) Electrotransfer of naked DNA in the skeletal muscles of animal models of muscular dystrophies. Gene Ther. 8, 1097-1107
20. Bachy, M. et al. (2001) Electric pulses increase the immunogenicity of an influenza DNA vaccine injected intramuscularly in the mouse. Vaccine 19, 1688-1693
21. Yang, N.S. et al. (1990) In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment. Proc. Natl. Acad. Sci. U. S. A. 87, 9568-9572
22. Wittig, B. et al. (2001) Therapeutic vaccination against metastatic carcinoma by expression-modulated and immunomodified autologous tumor cells: a first clinical phase I/II trial. Hum. Gene Ther. 12, 267-278
23. Sawamura, D. et al. (1999) In vivo gene introduction into keratinocytes using jet injection. Gene Ther. 6, 1785-1787
24. Taniyama, Y. et al. (2002) Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle. Gene Ther. 9, 372-380
25. Endoh, M. et al. (2002) Fetal gene transfer by intrauterine injection with microbubble enhanced ultrasound. Mol. Ther. 5, 501-508
26. Price, R.J. and Kaul, S. (2002) Contrast ultrasound targeted drug and gene delivery an update on a new therapeutic modality. J. Cardiovasc. Pharmacol. Ther. 7, 171-180
27. Fenske, D.B. et al. (2002) Stabilized plasmid-lipid particles: A systemic gene therapy vector. Methods Enzymol. 346, 36-71
28. Tam, P. et al. (2000) Stabilized plasmid-lipid particles for systemic gene therapy. Gene Ther. 7, 1867-1874
29. Nabel, G.J. et al. (1996) Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes. Proc. Natl. Acad. Sci. U. S. A. 93, 15388-15393
30. Stopeck, A.T. et al. (1997) Phase I study of direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7, in patients with metastatic melanoma. J. Clin. Oncol. 15, 341-349
31. Galanis, E. et al. (1999) Immunotherapy of advanced malignancy by direct gene transfer of an IL-2 DNA/DMRIE/DOPE lipid complex (Leuvectin): phase I/II experience. J. Clin. Oncol. 17, 3313-3323
32. Han, S-O. et al. (2000) Development of biomaterials for gene therapy. Mol. Ther. 2, 302-317
33. Luo, D. and Saltzman, W.M. (2000) Synthetic DNA delivery systems. Nat. Biotechnol. 18, 33-37
34. Gijsens, A. et al. (2002) Targeting of the photocytotoxic compound A1PcS4 to Hela cells by transferrin conjugated PEG-liposomes. Int. J. Cancer 101, 78-85
35. Kullberg, E. et al. (2002) Development of EGF-conjugated liposomes for targeted delivery of boronated DNA-binding agents. Bioconjug. Chem. 13, 737-743
36. Hofland, H.E. et al. (2002) Folate-targeted gene transfer in vivo. Mol. Ther. 5, 739-744
37. Reddy, J.A. et al. (2002) Folate-targeted, cationic liposome-mediated gene transfer into disseminated peritoneal tumors. Gene Ther. 9, 1542-1550
38. Carlisle, R.C. et al. (2001) Adenovirus hexon protein enhances nuclear delivery and increases transgene expression of polyethylenimine/plasmid DNA vectors. Mol. Ther. 4, 473-483
39. Curiel, D.T. et al. (1991) Adenovirus enhancement of transferrinpolylysine-mediated gene delivery. Proc. Natl. Acad. Sci. U. S. A. 88, 8850-8854
40. Kaneda, Y. et al. (1989) Increased expression of DNA cointroduced with nuclear protein in adult rat liver. Science 243, 375-378
41. Schuster, M.J. et al. (1999) Multicomponent DNA carrier with a vesicular stomatitis virus G-peptide greatly enhances liver-targeted gene expression in mice. Bioconjug. Chem. 10, 1075-1083
42. Niidome, T. et al. (2000) Gene transfer into hepatoma cells mediated by galactose-modified α-helical peptides. Biomaterials 21, 1811-1819
43. Mahato, R.I. (1999) Non-viral peptide-based approaches to gene delivery. J. Drug Target. 7, 249-268
44. Lunsford, L. et al. (2000) Tissue distribution and persistence in mice of plasmid DNA encapsulated in a PLGA-based microsphere delivery vehicle. J. Drug Target. 8, 39-50
45. Hood, J.D. et al. (2002) Tumor regression by targeted gene delivery to the neovasculature. Science 296, 2404-2407
46. Scherer, F. et al. (2002) Magnetofection: enhancing and targeting gene delivery by magnetic force in vitro and in vivo. Gene Ther. 9, 102-109
47. Ponimaskin, E. et al. (2000) Sendai virosomes revisited: reconstitution with exogenous lipids leads to potent vehicles for gene transfer. Virology 269, 391-403
48. Veelken, H. and Rosenthal, F.M. (2002) Somatische gentherapie. In Das Rote Buch (Berger, D.P. et al., eds), Ecomed Verlagsgesellschaft
49. Günzburg, W.H. and Salmons, B. (1997) Physikalische gentransfermethoden. In Gentransfer in Säugetierzellen, pp. 19-32, Spektrum Akademischer Verlag
50. Schatzlein, A.G. (2001) Non-viral vectors in cancer gene therapy: principles and progress. Anticancer Drugs 12, 275-304