Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

Genes and Development

Volumn 16, Issue 8, 2002, Pages 948-958

  Paddison, Patrick J ^a   Caudy, Amy A ^b   Bernstein, Emily ^c   Hannon, Gregory J ^c   Conklin, Douglas S ^b  

^a WATSON SCHOOL OF BIOLOGICAL SCIENCES   (United States)

^b Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^c STONY BROOK UNIVERSITY   (United States)

Author keywords

Gene silencing; miRNA; RNAi; shRNA; siRNA

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; DOUBLE STRANDED RNA; MESSENGER RNA; RNA; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CAENORHABDITIS ELEGANS; CELL LINE; DNA SEQUENCE; DROSOPHILA; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC ENGINEERING; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; RNA TRANSCRIPTION; TRANSGENIC ANIMAL;

3T3 CELLS; ANIMALS; CELL LINE; CONSERVED SEQUENCE; COS CELLS; DROSOPHILA; ENDORIBONUCLEASES; GENE EXPRESSION; GENE SILENCING; HUMANS; MICE; RIBONUCLEASE III; RNA; RNA POLYMERASE III; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; SUBSTRATE SPECIFICITY; TRANSFECTION;

ANIMALIA; CAENORHABDITIS; CAENORHABDITIS ELEGANS; EUKARYOTA; INVERTEBRATA; MAMMALIA;

EID: 0037089589     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.981002     Document Type: Article

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