High efficiency gene transfer to the central nervous system of rodents and primates using herpes virus vectors lacking functional ICP27 and ICP34.5

Gene Therapy

Volumn 5, Issue 8, 1998, Pages 1137-1147

  Howard, M K ^a   Kershaw, T ^a   Gibb, B ^a   Storey, N ^a,b   MacLean, A R ^c   Zeng, B Y ^d   Tel, B C ^d   Jenner, P ^d   Brown, S M ^c   Woolf, C J ^a   Anderson, P N ^a   Coffin, R S ^a   Latchman, D S ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b Novartis Inst for Medical Research   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Central nervous system; Gene delivery; Herpes vector; Primate brain; Rat brain

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; EXPRESSION VECTOR; FEMALE; GENE TARGETING; HERPES VIRUS; MALE; MARKER GENE; NONHUMAN; PRIORITY JOURNAL; RAT; VIRUS GENE; VIRUS MUTANT;

ANIMALIA; HERPES; HERPESVIRIDAE; PRIMATES; RODENTIA; SIMPLEXVIRUS;

EID: 7344259640     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300700     Document Type: Article

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