Multiple immediate-early gene-deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system in vivo

Journal of Virology

Volumn 75, Issue 9, 2001, Pages 4343-4356

  Lilley, C E ^a   Groutsi, F ^a   Han, Z ^a   Palmer, J A ^a   Anderson, P N ^a   Latchman, D S ^a   Coffin, R S ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ETOPOSIDE; VIRUS VECTOR;

ANIMAL CELL; ARTICLE; BRAIN STEM; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CORPUS STRIATUM; GENE ACTIVATION; GENE EXPRESSION; GENE INACTIVATION; GENE MUTATION; GENE TARGETING; HERPES SIMPLEX VIRUS 1; IMMEDIATE EARLY GENE; IN VIVO STUDY; NERVE CELL CULTURE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; RETINA GANGLION CELL; SPINAL GANGLION; SUBSTANTIA NIGRA; SUPERIOR COLLICULUS; THALAMUS; TRANSGENE; VIRUS INFECTION;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CELL LINE; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CERCOPITHECUS AETHIOPS; CRICETINAE; DEFECTIVE VIRUSES; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENES, IMMEDIATE-EARLY; GENES, REPORTER; GENES, VIRAL; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HERPES SIMPLEX VIRUS PROTEIN VMW65; HERPESVIRUS 1, HUMAN; HUMANS; IMMEDIATE-EARLY PROTEINS; INJECTIONS; LAC OPERON; LUMINESCENT PROTEINS; MALE; MUTAGENESIS, INSERTIONAL; NEURONS; PROMOTER REGIONS (GENETICS); RATS; RATS, INBRED LEW; TRANSGENES; UBIQUITIN-PROTEIN LIGASES; VERO CELLS; VIRAL PROTEINS;

EID: 0035043465     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.9.4343-4356.2001     Document Type: Article

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